Correlation between pulse wave velocity and fluid distribution in hemodialysis patients.

Abstract:

BACKGROUND:In this study, we focused on whether volume overload plays a role in the development of arterial stiffness. METHODS:Seventy-three prevalent hemodialysis patients were enrolled in a cross-sectional study. Arterial stiffness was assessed by carotid-femoral pulse wave velocity (PWV), and volume overload was assessed by bioimpedance analysis. RESULTS:Patients were divided into a high PWV group and a low PWV group based on the median of PWV. Age, systolic blood pressure, pulse pressure (PP), extracellular water/total body water ratio (ECW/TBW), diabetic status (all p < 0.01), and history of cardiac events (p < 0.05) were significantly higher in the high PWV group (n = 37) than in the low PWV group. In the correlation analysis, PWV was positively associated with PP, systolic blood pressure, ECW/TBW, age, history of cardiac events, and diabetes (all p < 0.01). Multiple regression analysis showed that PWV was independently related to PP and ECW/TBW (p < 0.01). CONCLUSION:Volume overload plays an important role in the development of arterial stiffness in hemodialysis patients.

journal_name

Blood Purif

journal_title

Blood purification

authors

Zheng D,Cheng LT,Zhuang Z,Gu Y,Tang LJ,Wang T

doi

10.1159/000199432

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

248-52

issue

3

eissn

0253-5068

issn

1421-9735

pii

000199432

journal_volume

27

pub_type

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