Peritoneal membrane evaluation in routine clinical practice.


BACKGROUND/AIMS:Establishment of reference values for small solute transport, sodium sieving and effluent CA125 with 3.86% (4 h) peritoneal equilibration test (PET), and comparison with fast-fast PET with regard to small solute transport categories. METHODS:Cross-sectional study; 69 prevalent patients. Sodium sieving corrected for sodium diffusion with a formula applicable to the PET. CA125 appearance rate (AR) was measured. Expected and observed 60 min D/P(creatinine) were compared by Bland and Altman. RESULTS:Means (95% CI): D/P(creatinine) 0.73 (0.70-0.76), MTAC(creatinine) 9.6 (8.4-10.9) ml/min, D/D0 glucose 0.30 (0.28-0.31), corrected dip 0.17 (0.15-0.18), CA125 150 (125-176) U/min. Both corrected and uncorrected sodium sieving were informative. Peritoneal transport was faster at 60 min dwell. UFF patients presented very low corrected dip and CA125 AR. CONCLUSION:3.86% (4 h) PET provided results similar to those from SPA. Correction for diffusion of sodium sieving is dispensable for simple clinical evaluations. D/P(creatinine) at 60 min overestimated small solute transport rate. Effluent CA125 was consistently lower in UFF patients.


Blood Purif


Blood purification


Rodrigues AS,Silva S,Bravo F,Oliveira JC,Fonseca I,Cabrita A,Krediet RT




Has Abstract


2007-01-01 00:00:00














  • Enhanced functional performance characteristics of a new polysulfone membrane for high-flux hemodialysis.

    abstract::Elimination of uremic solutes with molecular weights up to 60 kD, without significant loss of albumin is an important therapeutic goal to optimize outcomes in chronic hemodialysis patients. To characterize a newly developed polysulfone dialyzer (APS-650) a comparative analysis was performed with a highly advanced poly...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Klingel R,Ahrenholz P,Schwarting A,Röckel A

    更新日期:2002-01-01 00:00:00

  • Determinants of N-terminal pro-brain natriuretic peptide variation in hemodialysis patients and prediction of survival.

    abstract:BACKGROUND/AIMS:N-Terminal pro-brain natriuretic peptide (NT-proBNP) is a predictor of cardiac events and death in the general population and in chronic kidney disease. There is limited information on how natriuretic peptides vary in dialysis patients. The aim of this study was to analyze NT-proBNP variability, factors...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Snaedal S,Qureshi AR,Carrero JJ,Heimbürger O,Stenvinkel P,Bárány P

    更新日期:2014-01-01 00:00:00

  • Ischemic Heart Disease in Patients with End-Stage Kidney Disease.

    abstract:BACKGROUND:It was recently reported that the severity of coronary and carotid atherosclerosis in patients with end-stage kidney disease (ESKD) has improved over the last two decades. However, the frequency of coronary artery events observed at the initiation of dialysis remains high. SUMMARY:Recently, 5 different clin...

    journal_title:Blood purification

    pub_type: 评论,杂志文章


    authors: Tanaka Y,Joki N,Hase H

    更新日期:2015-01-01 00:00:00

  • What can we expect from on-line hemodiafiltration?

    abstract::On-line hemodiafiltration (ol-HDF) may improve clinical outcome in ESRD. The supposed mechanism is the improved clearance of uremic toxins by convective transport which is added to the diffusion transport. However, recent marked improvement in the performance of dialyzers has allowed higher removal rate of middle to l...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Kawanishi H

    更新日期:2013-01-01 00:00:00

  • Management of acute decompensated heart failure: renal implications.

    abstract::Heart failure (HF) is a chronic disease process associated with significant morbidity and mortality. Hospitalizations for acute decompensation may be frequent and herald a downward trajectory for the underlying disease state and overall poor prognosis for the patient. While significant advances have been made in the r...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Virani SA

    更新日期:2008-01-01 00:00:00

  • Amino acids and keto acids in the treatment of chronic renal failure.

    abstract::Clinical trials using very low protein supply supplemented with amino acid or keto acid preparations have shown the possibility of slowing the rate of decline of renal function in patients with advanced chronic renal failure together with preservation of nutritional status. The possible mechanisms by which this effect...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章,评审


    authors: Jungers P,Chauveau P

    更新日期:1988-01-01 00:00:00

  • Entropy of uremia and dialysis technology.

    abstract::The second law of thermodynamics applies with local exceptions to patient history and therapy interventions. Living things preserve their low level of entropy throughout time because they receive energy from their surroundings in the form of food. They gain their order at the expense of disordering the nutrients they ...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Ronco C

    更新日期:2013-01-01 00:00:00

  • Bioartificial kidney alters cytokine response and hemodynamics in endotoxin-challenged uremic animals.

    abstract::The mortality from sepsis complicated by renal failure remains extremely high despite the application of modern renal replacement therapy. This study investigated whether treatment with a bioartificial kidney consisting of a hemofilter in a continuous venovenous hemofiltration circuit (CVVH) with a cartridge containin...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Fissell WH,Dyke DB,Weitzel WF,Buffington DA,Westover AJ,MacKay SM,Gutierrez JM,Humes HD

    更新日期:2002-01-01 00:00:00

  • Extracorporeal Blood Purification and Organ Support in the Critically Ill Patient during COVID-19 Pandemic: Expert Review and Recommendation.

    abstract::Critically ill COVID-19 patients are generally admitted to the ICU for respiratory insufficiency which can evolve into a multiple-organ dysfunction syndrome requiring extracorporeal organ support. Ongoing advances in technology and science and progress in information technology support the development of integrated mu...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Ronco C,Bagshaw SM,Bellomo R,Clark WR,Husain-Syed F,Kellum JA,Ricci Z,Rimmelé T,Reis T,Ostermann M

    更新日期:2021-01-01 00:00:00

  • Natural killer cell dysfunction in uremia: the role of oxidative stress and the effects of dialysis.

    abstract::Immune deficiency is one of the numerous consequences of chronic renal failure. We can hypothesize that an abnormal natural killer (NK) cell response is present in patients with end-stage renal disease (ESRD). To characterize the immune defect in ESRD patients, we performed a NK cell subset analysis in 66 patients wit...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Peraldi MN,Berrou J,Métivier F,Toubert A

    更新日期:2013-01-01 00:00:00

  • Diffusion kinetics in blood during haemodialysis and in vivo clearance of inorganic phosphate.

    abstract::Contradictory data are reported in the literature concerning the diffusion kinetics of inorganic phosphates (iPh) between red blood cells and plasma during haemodialysis. Accordingly, we performed mass balance and equilibration studies to analyze the diffusion kinetics of iPh in vivo and in vitro. Mass balance analysi...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Descombes E,Jutzet A,Perriard F,Fellay G

    更新日期:2001-01-01 00:00:00

  • Improvements in technology: a path to safer and more effective hemodialysis.

    abstract::Effective dialysis therapy is now understood to encompass both small and large solute removal, using approaches that minimize intradialytic symptoms and maximize patient safety. Achieving the goal of providing effective dialysis for an expanding population of patients with increasingly complex medical problems at a ti...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Ward RA,Ronco C

    更新日期:2009-01-01 00:00:00

  • Are both psychological and physical dimensions in health-related quality of life associated with mortality in hemodialysis patients: a 7-year Taiwan cohort study.

    abstract:BACKGROUND:Psychological depression and physical disability are closely correlated in hemodialysis patients. A retrospective cohort study was conducted to examine the independent association of physical and psychological functioning with mortality in a hemodialysis cohort in Taiwan. METHODS:A total of 888 stable hemod...

    journal_title:Blood purification

    pub_type: 杂志文章,多中心研究


    authors: Peng YS,Chiang CK,Hung KY,Chang CH,Lin CY,Yang CS,Chen TW,Hsia CC,Chen DL,Hsu WD,Chang CF,Wu KD,Lin RP,Tsai TJ,Chen WY

    更新日期:2010-01-01 00:00:00

  • Prevention of Intradialytic Hypotension with Intermittent Back-Filtrate Infusion Haemodiafiltration: Insights into the Underlying Mechanism.

    abstract:BACKGROUND:Intradialytic hypotension (IDH) is a major challenge to safely performing haemodialysis. Blood volume depletion due to fluid removal is a major cause of hypotension, so more emphasis should be placed on finding alternative modalities to traditional constant rate ultrafiltration. SUMMARY:Intermittent back-fi...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Koda Y,Aoike I

    更新日期:2019-01-01 00:00:00

  • Homocysteine-lowering vitamin B treatment decreases cardiovascular events in hemodialysis patients.

    abstract:BACKGROUND:Dialysis patients have higher cardiovascular events rate than patients with normal renal function. Hyperhomocysteinemia, a risk factor for cardiovascular disease, is frequently detected in dialysis patients. Vitamin B supplementation lowers hyperhomocysteinemia, but it is unknown whether it reduces cardiovas...

    journal_title:Blood purification

    pub_type: 杂志文章,随机对照试验


    authors: Righetti M,Serbelloni P,Milani S,Ferrario G

    更新日期:2006-01-01 00:00:00

  • Improving Erythropoiesis Stimulating Agent Hyporesponsiveness in Hemodialysis Patients: The Role of Hepcidin and Hemodiafiltration Online.

    abstract::Hyporesponsiveness to erythropoietin stimulating agents (ESAs) is a condition associated with increased mortality. Even after identifying the condition, the causes are difficult to treat and only partially reversible in end-stage renal disease patients. Thus, the role of more recent hemodialysis (HD) techniques in imp...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Rosati A,Ravaglia F,Panichi V

    更新日期:2018-01-01 00:00:00

  • Continuous hemofiltration in 2009: what is new for clinicians regarding pathophysiology, preferred technique and recommended dose?

    abstract::In the last years, publications have questioned the classical dose of 35 ml/kg, but are those studies strong enough in terms of scientific power in order to change our practice? We will try to settle some recommendations for clinicians. Manipulation of dose, porosity, and combinations have yielded promising findings. ...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Honoré PM,Joannes-Boyau O,Collin V,Boer W,Jennes S

    更新日期:2009-01-01 00:00:00

  • Plasma dimethylarginine levels in chronic hemodialysis patients are independent of the type of dialyzer applied.

    abstract:BACKGROUND:Asymmetric dimethylarginine (ADMA) levels are increased in hemodialysis (HD) patients. Reports on the effect of various dialysis strategies on ADMA, symmetric dimethylarginine (SDMA) and L-arginine levels are inconclusive. PATIENTS/METHODS:In this randomized crossover study, 15 patients were dialyzed for 4 ...

    journal_title:Blood purification

    pub_type: 杂志文章,随机对照试验


    authors: Grooteman MP,Wauters IM,Teerlink T,Twisk JW,Nubé MJ

    更新日期:2007-01-01 00:00:00

  • High Ferritin Level and Malnutrition Predict High Risk of Infection-Related Hospitalization in Incident Dialysis Patients: A Japanese Prospective Cohort Study.

    abstract:AIMS:The aim of the study was to clarify the relationship between serum ferritin and infectious risks. METHODS:We evaluated all hospital admissions due to infections, clinical biomarkers and nutrition status in 129 incident Japanese dialysis patients during a median follow-up of 38 months. RESULTS:Kaplan-Meier analys...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Kato S,Lindholm B,Yuzawa Y,Tsuruta Y,Nakauchi K,Yasuda K,Sugiura S,Morozumi K,Tsuboi N,Maruyama S

    更新日期:2016-01-01 00:00:00

  • Kidney transplantation improves sleep-related breathing in hemodialysis patients.

    abstract:AIMS:To assess whether kidney transplantation improves sleep-related breathing disorders associated with hemodialysis. METHODS:A prospective study was carried out using full-night polysomnography. Nine hemodialysis patients (7 men and 2 women, aged 42 +/- 16.2 years, BMI 26 +/- 3.7) who later received a successful kid...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章


    authors: Jurado-Gámez B,Martin-Malo A,Rodriguez-Benot A,Muñoz-Cabrera L,Cosano Povedano A,Aljama P

    更新日期:2008-01-01 00:00:00

  • Assessment of inflow of endotoxin and its fragments in patients on maintenance hemodialysis.

    abstract:BACKGROUND:We estimated the flow of endotoxins (ET) from dialysates into the blood of patients on hemodialysis (HD) using limulus amebocyte lysate (LAL) assays and endotoxin activity (EA) determined by neutrophil respiratory burst activity. METHODS:A cross-sectional study compared groups given ultrapure bicarbonate (n...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Suzuki H,Honda H,Kato N,Michihata T,Takahashi K,Shishido K,Akizawa T

    更新日期:2011-01-01 00:00:00

  • Regulation of the response to bacterial lipopolysaccharide by endogenous and exogenous lipopolysaccharide binding proteins.

    abstract::Bactericidal/permeability-increasing protein (BPI) is a natural constituent of human neutrophils. Recombinant BPI has been shown to bind to bacterial lipopolysaccharide (LPS), and to neutralize the ability of LPS to stimulate inflammatory cells in vitro and in vivo. BPI shares sequence homology and immunocrossreactivi...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Marra MN,Thornton MB,Snable JL,Leong S,Lane J,Wilde CG,Scott RW

    更新日期:1993-01-01 00:00:00

  • Peritoneal Dialysis Treatment Modality Option in Acute Kidney Injury.

    abstract:BACKGROUND:Peritoneal dialysis (PD) may be a feasible and safe alternative to haemodialysis not only in the chronic but also in the acute setting. It was previously widely accepted as a modality for acute kidney injury (AKI) treatment, but its practice declined in favor of other types of extracorporeal therapies. SUMM...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Ponce D,Gobo-Oliveira M,Balbi AL

    更新日期:2017-01-01 00:00:00

  • Reduction of free immunoglobulin light chains using adsorption properties of hemodiafiltration with endogenous reinfusion.

    abstract::In this work we investigated the acute effects of hemodiafiltration with endogenous reinfusion (HFR therapy) on the removal of free immunoglobulin light chains (FIgLCs), which may be considered members of the family of uremic toxins. In two groups of patients - group 1 (polyclonal FIgLCs production) and group 2 (monoc...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Testa A,Dejoie T,Lecarrer D,Wratten M,Sereni L,Renaux JL

    更新日期:2010-01-01 00:00:00

  • Microcirculation: Physiology, Pathophysiology, and Clinical Application.

    abstract::This paper briefly reviews the physiological components of the microcirculation, focusing on its function in homeostasis and its central function in the realization of oxygen transport to tissue cells. Its pivotal role in the understanding of circulatory compromise in states of shock and renal compromise is discussed....

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Guven G,Hilty MP,Ince C

    更新日期:2020-01-01 00:00:00

  • Antibodies to periodontal organisms are associated with decreased kidney function. The Dental Atherosclerosis Risk In Communities study.

    abstract:BACKGROUND/AIMS:Increasing evidence suggests that clinical signs of periodontal disease are independently associated with renal impairment. However, no studies have examined the possible linkage of kidney disease with serum antibody to oral pathogens. METHODS:The periodontal disease status was assessed in an older com...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Kshirsagar AV,Offenbacher S,Moss KL,Barros SP,Beck JD

    更新日期:2007-01-01 00:00:00

  • Benefit of glucose-free dialysis solutions on glucose and lipid metabolism in peritoneal dialysis patients.

    abstract:BACKGROUND:Glucose absorbed from conventional peritoneal dialysis (PD) solutions contributes to unfavorable metabolic effects. Its replacement with a glucose-free osmotic agent such as icodextrin (ID) or amino acids (AA) may have some benefit on glucose and lipid metabolism. METHODS:Serum lipids, insulin sensitivity a...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Martikainen T,Teppo AM,Gronhagen-Riska C,Ekstrand A

    更新日期:2005-01-01 00:00:00

  • Two-compartment model of cholesterol kinetics for establishment of treatment strategy of LDL apheresis in nephrotic hypercholesterolemia.

    abstract::Cholesterol kinetics in the time course after LDL apheresis using a dextran sulfate cellulose column was analyzed by adapting a two-compartment cholesterol kinetic model. Fifteen sets of serial serum cholesterol concentrations after LDL apheresis from 4 patients with drug-resistant nephrotic hypercholesterolemia due t...

    journal_title:Blood purification

    pub_type: 杂志文章


    authors: Yashiro M,Muso E,Matsushima M,Nagura R,Sawanishi K,Sasayama S

    更新日期:1994-01-01 00:00:00

  • ADEMEX and HEMO trials: where are we going?

    abstract::Doubt has remained as to whether or not the K/DOQI recommended targets for adequacy of dialysis for peritoneal dialysis patients is appropriate (weekly Kt/V 2 + creatinine clearance 50-60 l/1.73 m(2)). The ADEMEX trial can be interpreted as indicating that lower targets might be acceptable. The HEMO trial, not yet pub...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章


    authors: Prichard S

    更新日期:2003-01-01 00:00:00

  • Hemodynamic stability during different forms of dialysis therapy: a pathogenetic analysis.

    abstract::Pathophysiological aspects of plasma volume preservation and cardiovascular reactivity are reviewed, comparing combined ultrafiltration-hemodialysis with isolated ultrafiltration and hemofiltration. The role of different factors in the disparity in cardiovascular reactivity between these treatments is discussed. ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审


    authors: Hendrikus W,van Kuijk M,Leunissen KM

    更新日期:1996-01-01 00:00:00