Peritoneal membrane evaluation in routine clinical practice.

Abstract:

BACKGROUND/AIMS:Establishment of reference values for small solute transport, sodium sieving and effluent CA125 with 3.86% (4 h) peritoneal equilibration test (PET), and comparison with fast-fast PET with regard to small solute transport categories. METHODS:Cross-sectional study; 69 prevalent patients. Sodium sieving corrected for sodium diffusion with a formula applicable to the PET. CA125 appearance rate (AR) was measured. Expected and observed 60 min D/P(creatinine) were compared by Bland and Altman. RESULTS:Means (95% CI): D/P(creatinine) 0.73 (0.70-0.76), MTAC(creatinine) 9.6 (8.4-10.9) ml/min, D/D0 glucose 0.30 (0.28-0.31), corrected dip 0.17 (0.15-0.18), CA125 150 (125-176) U/min. Both corrected and uncorrected sodium sieving were informative. Peritoneal transport was faster at 60 min dwell. UFF patients presented very low corrected dip and CA125 AR. CONCLUSION:3.86% (4 h) PET provided results similar to those from SPA. Correction for diffusion of sodium sieving is dispensable for simple clinical evaluations. D/P(creatinine) at 60 min overestimated small solute transport rate. Effluent CA125 was consistently lower in UFF patients.

journal_name

Blood Purif

journal_title

Blood purification

authors

Rodrigues AS,Silva S,Bravo F,Oliveira JC,Fonseca I,Cabrita A,Krediet RT

doi

10.1159/000113009

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

497-504

issue

5-6

eissn

0253-5068

issn

1421-9735

pii

000113009

journal_volume

25

pub_type

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