Improvements in technology: a path to safer and more effective hemodialysis.

abstract：:Reprocessing of used dialyzers with chemical disinfectants is practiced commonly in the United States and in some areas of Western Europe. Concern over residual toxic or allergenic agents has encouraged the search for other practical methods to disinfect or sterilize used hemodialyzers. The use of moist heat has been ...

journal_title：Blood purification

authors： Holmes CJ

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The number of patients receiving renal replacement therapy (RRT) increases annually and worldwide. Differences in the RRT incidence, prevalence, and modality vary between regions and countries for reasons yet to be clarified. AIMS:Gain a better understanding of the association between hemodialysis (HD)-rela...

journal_title：Blood purification

authors： Calice-Silva V,Hussein R,Yousif D,Zhang H,Usvyat L,Campos LG,von Gersdorff G,Schaller M,Marcelli D,Grassman A,Etter M,Xu X,Kotanko P,Pecoits-Filho R

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Anemia is a major complication of end-stage renal disease. Hemodialysis itself is regarded as a stimulus activating inflammation. Pro-inflammatory cytokines are able to suppress erythropoiesis. In this pilot study, we analyzed the changes in methylation status of promoters of immune response genes in cell-fr...

journal_title：Blood purification

authors： Korabecna M,Pazourkova E,Horinek A,Mokrejsova M,Tesar V

更新日期：2013-01-01 00:00:00

abstract：:Issues in biocompatibility have traditionally focused on the interaction of membranes or materials with the activation of complement, red blood cell destruction, clotting dysfunctions, and platelet activation. Other studies are concerned with the replacement fluid formulations and host responses. Recent attention has ...

journal_title：Blood purification

authors： Dinarello CA

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND/AIMS:Peritonitis remains a significant problem for patients on peritoneal dialysis (PD). There is a certain amount of controversy as to whether peritoneal modality is itself a risk factor for peritonitis, with one modality higher than another. METHODS:A literature review was done (August 2009) searching und...

journal_title：Blood purification

authors： Piraino B,Sheth H

更新日期：2010-01-01 00:00:00

abstract：:In hemodialysis patients, C-reactive protein (CRP), an acute-phase reactant, is a sensitive and independent marker of malnutrition, anemia, and amyloidosis. The aim of the present studies was to evaluate CRP and interleukin 6 levels in plasma samples from long-term hemodialysis patients on different extracorporeal mod...

journal_title：Blood purification

authors： Panichi V,Migliori M,De Pietro S,Metelli MR,Taccola D,Perez R,Palla R,Rindi P,Cristofani R,Tetta C

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:We proposed a new method to estimate dry weight (DW) using single frequency bioimpedance. METHODS:We hypothesized that the change in whole body resistance at 50 kHz (R(50)) was proportional to the ultrafiltration volume (UFV) during a hemodialysis (HD) session. When the targeted resistance estimated in heal...

journal_title：Blood purification

authors： Dou Y,Cheng X,Liu L,Bai X,Wu L,Guo W,Zhao X,Wang F,Cao L,Zuo L

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:There is a clear association between one allele of the interleukin-1 receptor-antagonist gene (IL-1RN) and inflammatory diseases in which IL-1 is implicated. We evaluated patient survival and technique survival of peritoneal dialysis (PD) patients, while analyzing independent risk factors, in a PD progr...

journal_title：Blood purification

authors： Uchiyama K,Naito K,Tsuchida M,Takai K,Okayama N,Fujimura K,Hinoda Y

更新日期：2005-01-01 00:00:00

abstract：:In patients with chronic kidney disease (CKD), peptides and proteins circulate at altered concentrations versus in healthy individuals. We have characterized proteome samples from 7 pooled CKD stage 5 patients not yet on dialysis and with no known co-morbidities. We also analyzed pooled plasma samples from 7 healthy a...

journal_title：Blood purification

authors： Naseeb U,Shafqat J,Jägerbrink T,Zarina S,Alvestrand A,Jörnvall H,Axelsson J

更新日期：2008-01-01 00:00:00

abstract：:Clinical trials using very low protein supply supplemented with amino acid or keto acid preparations have shown the possibility of slowing the rate of decline of renal function in patients with advanced chronic renal failure together with preservation of nutritional status. The possible mechanisms by which this effect...

journal_title：Blood purification

authors： Jungers P,Chauveau P

更新日期：1988-01-01 00:00:00

abstract：:The effects of pulsatile perfusion on microcirculation and renal function in high-risk patients were evaluated in this study. Pulsatile roller pumps with a pulsatile control module and membrane oxygenator were used in a clinical setting. 40 patients undergoing elective cardiac surgery with a high risk of either having...

journal_title：Blood purification

authors： Kocakulak M,Aşkin G,Kuçukaksu S,Tarcan O,Pişkin E

更新日期：2005-01-01 00:00:00

abstract：:A review is given of the conditions associated with peritoneal membrane failure, and the possible causes. Ultrafiltration failure is the most important manifestation. It is mostly associated with high transport rates of low molecular weight solutes suggesting the presence of a large vascular surface area. Enlargement ...

journal_title：Blood purification

authors： Krediet RT,Van Esch S,Smit W,Michels WM,Zweers MM,Ho-Dac-Pannekeet MM,Struijk DG

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Removal of protein-bound uremic toxins by dialysis therapy is limited. The effect of oral adsorbent AST-120 in chronic dialysis patients has rarely been investigated. METHODS:AST-120 was administered 6.0 g/day for 3 months in 69 chronic dialysis patients. The blood concentrations of indoxyl sulfate, p-creso...

journal_title：Blood purification

authors： Lee CT,Hsu CY,Tain YL,Ng HY,Cheng BC,Yang CC,Wu CH,Chiou TT,Lee YT,Liao SC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Secondary hyperparathyroidism (SHP) is characterized by high bone turnover and elevated serum bone remodeling markers. Elevation of serum interleukin-6 (IL-6) levels is also characteristic of end-stage renal disease. This study investigates the effects of intravenous calcitriol on serum bone resorptive ...

journal_title：Blood purification

authors： Lu KC,Tseng CF,Wu CC,Yeung LK,Chen JS,Chao TY,Janckila AJ,Yam LT,Chu P

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) levels are increased in hemodialysis (HD) patients. Reports on the effect of various dialysis strategies on ADMA, symmetric dimethylarginine (SDMA) and L-arginine levels are inconclusive. PATIENTS/METHODS:In this randomized crossover study, 15 patients were dialyzed for 4 ...

journal_title：Blood purification

authors： Grooteman MP,Wauters IM,Teerlink T,Twisk JW,Nubé MJ

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Hypomagnesaemia is a cardiovascular (CV) risk factor in the general population. The aim of this study was to evaluate the relationship between pre-dialysis magnesium (Mg) and CV risk markers, [including pulse pressure (PP), left ventricular mass index (LVMI) and vascular calcifications (VC)], and mortality i...

journal_title：Blood purification

authors： João Matias P,Azevedo A,Laranjinha I,Navarro D,Mendes M,Ferreira C,Amaral T,Jorge C,Aires I,Gil C,Ferreira A

更新日期：2014-01-01 00:00:00

abstract：:In the last years, publications have questioned the classical dose of 35 ml/kg, but are those studies strong enough in terms of scientific power in order to change our practice? We will try to settle some recommendations for clinicians. Manipulation of dose, porosity, and combinations have yielded promising findings. ...

journal_title：Blood purification

authors： Honoré PM,Joannes-Boyau O,Collin V,Boer W,Jennes S

更新日期：2009-01-01 00:00:00

abstract：:Bactericidal/permeability-increasing protein (BPI) is a natural constituent of human neutrophils. Recombinant BPI has been shown to bind to bacterial lipopolysaccharide (LPS), and to neutralize the ability of LPS to stimulate inflammatory cells in vitro and in vivo. BPI shares sequence homology and immunocrossreactivi...

journal_title：Blood purification

authors： Marra MN,Thornton MB,Snable JL,Leong S,Lane J,Wilde CG,Scott RW

更新日期：1993-01-01 00:00:00

abstract：:We have investigated the effect of the direction of the dialysate flow during continuous arteriovenous haemodialysis. Under similar conditions countercurrent flow was more efficient than concurrent flow in terms of both urea clearance (mean +/- SEM), 23.5 +/- 0.5 compared to 18.4 +/- 0.4 ml/min (p less than 0.001) and...

journal_title：Blood purification

authors： Davenport A,Will EJ,Davison AM

更新日期：1990-01-01 00:00:00

abstract：AIMS:To study incidence, clinical features, and outcome of critically ill patients with end-stage renal failure (ESRF) requiring renal replacement therapy (RRT) in the intensive care unit (ICU) and to test the validity of severity scoring systems for these patients. METHODS:Data for ESRF patients treated with RRT were...

journal_title：Blood purification

authors： Uchino S,Morimatsu H,Bellomo R,Silvester W,Cole L

更新日期：2003-01-01 00:00:00

abstract：:Haemodialysis is associated with increased oxidant stress. This appears to be due to (1) an increased production of free radicals during haemodialysis, (2) a net reduction of many antioxidants and (3) factors intrinsic to the uremic state. These alterations can lead to cardiovascular disease and many of the pathologie...

journal_title：Blood purification

authors： Wratten ML,Navino C,Tetta C,Verzetti G

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIMS:Carpal tunnel syndrome (CTS) is a common clinical presentation of dialysis-related amyloidosis. It was determined whether β(2)-microglobulin (β2M) and advanced glycation end products in serum are predictors of CTS in dialysis patients. METHODS:A total of 385 hemodialysis patients were screened for CTS....

journal_title：Blood purification

authors： Busch M,Schwenzky A,Franke S,Stein G,Wolf G

更新日期：2012-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) is associated with multiple detrimental consequences to the cardiovascular and musculoskeletal systems. The effects of CKD are even more significant when they begin in childhood as they affect growth and (neuro-) development as well. The division into stages of CKD serves as a guideline fo...

journal_title：Blood purification

authors： Goilav B,Kaskel FJ

更新日期：2011-01-01 00:00:00

abstract：:The recent interest in the role of the intestine in the cardiovascular stability of uremic patients, specifically on dialysis, but potentially also in chronic kidney disease, must be seen against the background of the recent great interest in the role of the gut in chronic heart failure [Curr Opin Clin Nutr Metab Care...

journal_title：Blood purification

authors： Ritz E

更新日期：2011-01-01 00:00:00

abstract：:Cardiovascular disease (CVD) remains the major cause of morbidity and mortality in end-stage renal disease (ESRD) patients. As traditional risk factors cannot alone explain the unacceptable high prevalence and incidence of CVD in this population, inflammation (a common phenomenon in ESRD), and other non-traditional ri...

journal_title：Blood purification

authors： Stenvinkel P,Lindholm B

更新日期：2005-01-01 00:00:00

abstract：:The evidence concerning online hemodiafiltration (HDF) includes the following: (1) the increase of removal of uremic toxin, (2) the prevention of dialysis rerated hypotension, (3) the recovery of survival, and (4) the recovery of dialysis related uncertain symptoms. Although clinical evidence has been noted, the hypot...

journal_title：Blood purification

authors： Kawanishi H

更新日期：2018-01-01 00:00:00

abstract：:Hyporesponsiveness to erythropoietin stimulating agents (ESAs) is a condition associated with increased mortality. Even after identifying the condition, the causes are difficult to treat and only partially reversible in end-stage renal disease patients. Thus, the role of more recent hemodialysis (HD) techniques in imp...

journal_title：Blood purification

authors： Rosati A,Ravaglia F,Panichi V

更新日期：2018-01-01 00:00:00

abstract：:The central dialysis fluid delivery system (CDDS) has been working exclusively in Japan since 1970, a fact which proves that CDDS is useful in the multi-patient treatment with in-center regular hemodialysis. It is a cost-effective, labor-saving and time-tested system with 40 years of experience. Microbial safety is im...

journal_title：Blood purification

authors： Koda Y,Mineshima M

更新日期：2009-01-01 00:00:00

abstract：:Plasma exchange (PE) is an effective therapeutic method used in patients with myasthenia gravis (MG) refractory to common therapy and/or with life-threatening respiratory complications. Except for acetylcholine receptor antibodies (AChRAbs), some other inflammatory mediators possibly activated in MG may also be remove...

journal_title：Blood purification

authors： Tesar V,Jelínková E,Jirsa M Jr,Bakosová M,Pitha P,Chábová V

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:Oxidative stress has been considered a nontraditional risk factor for cardiovascular disease in the chronic kidney disease (CKD) population, possibly triggered by uremic toxicity. METHODS:A chromatographic method with coulometric detection was adapted to directly and simultaneously determine cysteine (...

journal_title：Blood purification

authors： Rodrigues SD,Batista GB,Ingberman M,Pecoits-Filho R,Nakao LS

更新日期：2012-01-01 00:00:00