Pulsatile flow improves renal function in high-risk cardiac operations.

Abstract:

:The effects of pulsatile perfusion on microcirculation and renal function in high-risk patients were evaluated in this study. Pulsatile roller pumps with a pulsatile control module and membrane oxygenator were used in a clinical setting. 40 patients undergoing elective cardiac surgery with a high risk of either having chronically obstructive pulmonary disease or chronic renal failure were randomly included in the study to be perfused using pulsatile or continuous flows. Blood samples were collected at induction of anesthesia, at the time of aortic clamping and declamping and 1 and 24 h following cessation of the bypass. Urea and creatinine concentrations in blood were measured and systemic vascular resistance was calculated. Urine output, crystalloid and colloid infusions were recorded. We observed that pulsatile roller pump perfusion and the extracorporeal circuit used in the clinical study improved microcirculation and renal function in high-risk patients undergoing cardiopulmonary bypass.

journal_name

Blood Purif

journal_title

Blood purification

authors

Kocakulak M,Aşkin G,Kuçukaksu S,Tarcan O,Pişkin E

doi

10.1159/000085174

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

263-7

issue

4

eissn

0253-5068

issn

1421-9735

pii

85174

journal_volume

23

pub_type

临床试验,杂志文章,随机对照试验
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    pub_type: 临床试验,杂志文章,多中心研究

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    pub_type: 临床试验,杂志文章

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    pub_type: 杂志文章,评审

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    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

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