Antioxidant enzymes--superoxide dismutase and glutathione peroxidase--in haemodialyzed patients.

Abstract:

:The biological effect of oxygen-reactive species controlled by antioxidant mechanisms are exerted on the basis of antioxidant enzymes and substrates. In this study, the activities of antioxidant enzymes-superoxide dismutase (SOD) and glutathione peroxidase (GPx)-were determined in the erythrocytes of patients on regular haemodialysis treatment. The SOD activity was significantly lower (1,810.38 +/- 609.85 vs. 2,347.13 +/- 502.51 U/g haemoglobin, p < 0.05, or 70.71 +/- 11.50 vs. 100.13 +/- 24.28 mU/10(6) erythrocytes, p < 0.0001), as was the GPx activity (18.80 +/- 4.22 vs. 23.26 +/- 3.61 U/g haemoglobin, p < 0.01), when compared with the control group. A positive correlation between GPx activity and number of haemodialysis sessions was found (p = 0.0038), but no correlation between SOD activity and number of HD sessions. An inpaired antioxidant enzyme defence system, here represented by SOD and GPx levels, can potentiate injury caused by free radicals in haemodialysis patients.

journal_name

Blood Purif

journal_title

Blood purification

authors

Zima T,Stípek S,Crkovská J,Nĕmecek K,Pláteník J,Bártová V,Tesar V

doi

10.1159/000170269

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

257-61

issue

3

eissn

0253-5068

issn

1421-9735

journal_volume

14

pub_type

杂志文章
  • Effect of Early Cannulation with Plastic Cannula on Arteriovenous Fistula Patency in Hemodialysis Patients.

    abstract:INTRODUCTION:Plastic cannulas have been used to cannulate arteriovenous fistulas (AVFs) for hemodialysis (HD) in Japan for many years. However, the effect of early cannulation with plastic cannulas on AVF patency is not known. OBJECTIVE:We analyzed the relationship between first cannulation time (FCT) and patency rate...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000503678

    authors: Shi K,Jiang H,Wakabayashi M

    更新日期:2020-01-01 00:00:00

  • Improving Erythropoiesis Stimulating Agent Hyporesponsiveness in Hemodialysis Patients: The Role of Hepcidin and Hemodiafiltration Online.

    abstract::Hyporesponsiveness to erythropoietin stimulating agents (ESAs) is a condition associated with increased mortality. Even after identifying the condition, the causes are difficult to treat and only partially reversible in end-stage renal disease patients. Thus, the role of more recent hemodialysis (HD) techniques in imp...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000485314

    authors: Rosati A,Ravaglia F,Panichi V

    更新日期:2018-01-01 00:00:00

  • Intestinal-renal syndrome: mirage or reality?

    abstract::The recent interest in the role of the intestine in the cardiovascular stability of uremic patients, specifically on dialysis, but potentially also in chronic kidney disease, must be seen against the background of the recent great interest in the role of the gut in chronic heart failure [Curr Opin Clin Nutr Metab Care...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000321848

    authors: Ritz E

    更新日期:2011-01-01 00:00:00

  • Comparison of bioimpedance and clinical methods for dry weight prediction in maintenance hemodialysis patients.

    abstract:BACKGROUND:Bioelectrical impedance analysis (BIA) is a promising technique to evaluate dry weight. We compared the dry weight calculated by the three BIA equations Carlo Basile (CB) , Yanna Dou (YD) and the body composition spectroscopy (BCS) with clinical evaluation in maintenance hemodialysis (MHD) patients. METHODS...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章

    doi:10.1159/000362109

    authors: Jian Y,Li X,Cheng X,Chen Y,Liu L,Tao Z,Zuo L

    更新日期:2014-01-01 00:00:00

  • Biocompatibility of hemodialysis membranes: a study in healthy subjects.

    abstract::The effect of blood-membrane interaction on several biocompatibility parameters has been investigated. Four groups of healthy subjects underwent sham hemodialysis, i.e. the establishment of blood-dialysis membrane contact, but without circulating dialysate, using cellulose-based membranes (regenerated cellulose and ce...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000170153

    authors: Gutierrez A,Alvestrand A,Bergström J,Beving H,Lantz B,Henderson LW

    更新日期:1994-01-01 00:00:00

  • Sodium Intake and Blood Pressure in Patients with Chronic Kidney Disease: A Salty Relationship.

    abstract:BACKGROUND:Hypertension affects almost all chronic kidney disease patients and is related to poor outcomes. Sodium intake is closely related to blood pressure (BP) levels in this population and decreasing its intake consistently improves the BP control particularly in short-term controlled trials. However, most patient...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000485154

    authors: Nerbass FB,Calice-Silva V,Pecoits-Filho R

    更新日期:2018-01-01 00:00:00

  • Dialyzer reprocessing using heat. Scientific and technical considerations.

    abstract::Reprocessing of used dialyzers with chemical disinfectants is practiced commonly in the United States and in some areas of Western Europe. Concern over residual toxic or allergenic agents has encouraged the search for other practical methods to disinfect or sterilize used hemodialyzers. The use of moist heat has been ...

    journal_title:Blood purification

    pub_type:

    doi:10.1159/000170132

    authors: Holmes CJ

    更新日期:1993-01-01 00:00:00

  • Implementation of a Simplified Regional Citrate Anticoagulation Protocol for Post-Dilution Continuous Hemofiltration Using a Bicarbonate Buffered, Calcium Containing Replacement Solution.

    abstract:BACKGROUND/AIMS:Recent updates to the Nikkiso Aquarius continuous renal replacement therapy (CRRT) platform allowed us to develop a post-dilution protocol for regional citrate anticoagulation (RCA) using standard bicarbonate buffered, calcium containing replacement solution with acid citrate dextrose formula-A as a cit...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000452755

    authors: Kirwan CJ,Hutchison R,Ghabina S,Schwarze S,Beane A,Ramsay S,Thompson E,Prowle JR

    更新日期:2016-01-01 00:00:00

  • Leveraging Big Data and Electronic Health Records to Enhance Novel Approaches to Acute Kidney Injury Research and Care.

    abstract::While acute kidney injury (AKI) has been poorly defined historically, a decade of effort has culminated in a standardized, consensus definition. In parallel, electronic health records (EHRs) have been adopted with greater regularity, clinical informatics approaches have been refined, and the field of EHR-enabled care ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000458751

    authors: Sutherland SM,Goldstein SL,Bagshaw SM

    更新日期:2017-01-01 00:00:00

  • Development of intermittent infusion hemodiafiltration using ultrapure dialysis fluid with an automated dialysis machine.

    abstract::To reduce the potential occurrence of hypotension during a dialysis treatment, intermittent infusion hemodiafiltration (I-HDF) using back filtration with an ultrapure dialysis fluid was developed. Under typical I-HDF treatment conditions, some 200-300 ml of ultrapure dialysis fluid was infused into the blood component...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1159/000346371

    authors: Mineshima M,Eguchi K

    更新日期:2013-01-01 00:00:00

  • Failure of naloxone in reversal hemodialysis-induced hypotension.

    abstract::In 5 uremic patients the role of opioid peptides in dialysis-induced hypotension was investigated through the administration of naloxone. An intravenous bolus injection of 1 mg of naloxone was administered immediately before starting a routine hemodialysis session and was repeated when the patients' systolic arterial ...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000169411

    authors: Sturani A,Degli Esposti E,Chiarini C,Spongano M,Santoro A,Zucchelli P

    更新日期:1985-01-01 00:00:00

  • Diffusion kinetics in blood during haemodialysis and in vivo clearance of inorganic phosphate.

    abstract::Contradictory data are reported in the literature concerning the diffusion kinetics of inorganic phosphates (iPh) between red blood cells and plasma during haemodialysis. Accordingly, we performed mass balance and equilibration studies to analyze the diffusion kinetics of iPh in vivo and in vitro. Mass balance analysi...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000014470

    authors: Descombes E,Jutzet A,Perriard F,Fellay G

    更新日期:2001-01-01 00:00:00

  • Regulation of the response to bacterial lipopolysaccharide by endogenous and exogenous lipopolysaccharide binding proteins.

    abstract::Bactericidal/permeability-increasing protein (BPI) is a natural constituent of human neutrophils. Recombinant BPI has been shown to bind to bacterial lipopolysaccharide (LPS), and to neutralize the ability of LPS to stimulate inflammatory cells in vitro and in vivo. BPI shares sequence homology and immunocrossreactivi...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000170107

    authors: Marra MN,Thornton MB,Snable JL,Leong S,Lane J,Wilde CG,Scott RW

    更新日期:1993-01-01 00:00:00

  • Standardized Protocol for Hemodialysis Vascular Access Assessment: The Role of Ultrasound and ColorDoppler.

    abstract:INTRODUCTION:Ultrasound and colorDoppler technique, which is relatively inexpensive, rapid, non-invasive and repeatable is a powerful tool used for early diagnosis of vascular access (VA) complications in hemodialysis patients. To date a standard and widely comprehensible echocolorDoppler (ECD) protocol is not availabl...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000485590

    authors: Nalesso F,Garzotto F,Petrucci I,Samoni S,Virzì GM,Gregori D,Meola M,Ronco C

    更新日期:2018-01-01 00:00:00

  • Haemodialysis fluid: composition and clinical importance.

    abstract::Dialysis fluid is produced by the blending of treated water with electrolytes at the patients bed side. Its preparation and composition are important elements of treatment optimisation since many of the constituents play a role in patient well-being. Ideally the composition of the dialysis fluid should match that of p...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000096400

    authors: Hoenich NA,Ronco C

    更新日期:2007-01-01 00:00:00

  • Dietary and pharmacological control of calcium and phosphate metabolism in dialysis patients.

    abstract::Chronic kidney disease-mineral and bone disorder is a new term defining a complex syndrome which underlines the need of a systemic approach to disturbances of calcium and phosphate metabolism in patients with renal failure. In recent years, the availability of new phosphorus binders and the appearance of new selective...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000209250

    authors: Bover J,Andrés E,Lloret MJ,Aguilar A,Ballarín J

    更新日期:2009-01-01 00:00:00

  • Nocturnal Hemodialysis Compared with Conventional Dialysis for End-Stage Renal Disease Treatment in Polycystic Kidney Disease Patients.

    abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary cause of end-stage renal disease (ESRD). Little is known about outcomes after in-center nocturnal hemodialysis (NHD) treatment in ADPKD patients with ESRD. OBJECTIVES:This study aimed to evaluate the effects of in-center NHD ...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000503679

    authors: Xue C,Sun B,Ye X,Zhou C,Yang B,Zhang L,Yu S

    更新日期:2020-01-01 00:00:00

  • Are both psychological and physical dimensions in health-related quality of life associated with mortality in hemodialysis patients: a 7-year Taiwan cohort study.

    abstract:BACKGROUND:Psychological depression and physical disability are closely correlated in hemodialysis patients. A retrospective cohort study was conducted to examine the independent association of physical and psychological functioning with mortality in a hemodialysis cohort in Taiwan. METHODS:A total of 888 stable hemod...

    journal_title:Blood purification

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000319002

    authors: Peng YS,Chiang CK,Hung KY,Chang CH,Lin CY,Yang CS,Chen TW,Hsia CC,Chen DL,Hsu WD,Chang CF,Wu KD,Lin RP,Tsai TJ,Chen WY

    更新日期:2010-01-01 00:00:00

  • Why assistive technology is needed for probing of dry weight.

    abstract::Despite advancements in dialysis therapy, the subjective clinical examination still remains the standard of care in managing volume removal in chronic dialysis. While there is no definitive trial establishing that dry weight management guided by an assistive technology is superior to the clinical method, there is ampl...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000321840

    authors: Sinha AD

    更新日期:2011-01-01 00:00:00

  • Serum levels of 5-s-cysteinyldopa are correlated with skin colors in hemodialysis patients but not in peritoneal dialysis patients.

    abstract:BACKGROUND:Diffuse hyperpigmentation is common in patients with chronic renal failure undergoing hemodialysis (HD) or peritoneal dialysis (PD). We previously reported that serum levels of 5-S-cysteinyldopa (5SCD, a pheomelanin precursor) and pheomelanin were significantly elevated in HD patients. METHODS:Skin color wa...

    journal_title:Blood purification

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000230812

    authors: Murakami K,Nakanishi Y,Wakamatsu K,Yamamoto K,Kohriyama N,Hasegawa M,Tomita M,Nabeshima K,Hiki Y,Asano S,Kawashima S,Ito Y,Fujita Y,Asada H,Nakai S,Sugiyama S,Ito S

    更新日期:2009-01-01 00:00:00

  • Effects of calcitriol on type 5b tartrate-resistant acid phosphatase and interleukin-6 in secondary hyperparathyroidism.

    abstract:BACKGROUND/AIMS:Secondary hyperparathyroidism (SHP) is characterized by high bone turnover and elevated serum bone remodeling markers. Elevation of serum interleukin-6 (IL-6) levels is also characteristic of end-stage renal disease. This study investigates the effects of intravenous calcitriol on serum bone resorptive ...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1159/000094899

    authors: Lu KC,Tseng CF,Wu CC,Yeung LK,Chen JS,Chao TY,Janckila AJ,Yam LT,Chu P

    更新日期:2006-01-01 00:00:00

  • Amino acids and keto acids in the treatment of chronic renal failure.

    abstract::Clinical trials using very low protein supply supplemented with amino acid or keto acid preparations have shown the possibility of slowing the rate of decline of renal function in patients with advanced chronic renal failure together with preservation of nutritional status. The possible mechanisms by which this effect...

    journal_title:Blood purification

    pub_type: 临床试验,杂志文章,评审

    doi:10.1159/000169557

    authors: Jungers P,Chauveau P

    更新日期:1988-01-01 00:00:00

  • C-reactive protein in end-stage renal disease: are there reasons to measure it?

    abstract::Cardiovascular disease (CVD) remains the major cause of morbidity and mortality in end-stage renal disease (ESRD) patients. As traditional risk factors cannot alone explain the unacceptable high prevalence and incidence of CVD in this population, inflammation (a common phenomenon in ESRD), and other non-traditional ri...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000082014

    authors: Stenvinkel P,Lindholm B

    更新日期:2005-01-01 00:00:00

  • Enhanced functional performance characteristics of a new polysulfone membrane for high-flux hemodialysis.

    abstract::Elimination of uremic solutes with molecular weights up to 60 kD, without significant loss of albumin is an important therapeutic goal to optimize outcomes in chronic hemodialysis patients. To characterize a newly developed polysulfone dialyzer (APS-650) a comparative analysis was performed with a highly advanced poly...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000063099

    authors: Klingel R,Ahrenholz P,Schwarting A,Röckel A

    更新日期:2002-01-01 00:00:00

  • When should renal replacement therapy for acute kidney injury be initiated and discontinued?

    abstract:BACKGROUND:Critically ill patients with acute kidney injury (AKI) are at high risk for death and frequently require initiation of renal replacement therapy (RRT). There is wide variation in clinical practice on the indications for and timing of initiation and discontinuation of RRT. Numerous clinical and biochemical fa...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000157325

    authors: Gibney RT,Bagshaw SM,Kutsogiannis DJ,Johnston C

    更新日期:2008-01-01 00:00:00

  • Homocysteine-lowering vitamin B treatment decreases cardiovascular events in hemodialysis patients.

    abstract:BACKGROUND:Dialysis patients have higher cardiovascular events rate than patients with normal renal function. Hyperhomocysteinemia, a risk factor for cardiovascular disease, is frequently detected in dialysis patients. Vitamin B supplementation lowers hyperhomocysteinemia, but it is unknown whether it reduces cardiovas...

    journal_title:Blood purification

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000093680

    authors: Righetti M,Serbelloni P,Milani S,Ferrario G

    更新日期:2006-01-01 00:00:00

  • Intradialytic changes of plasma amino acid levels: effect of hemodiafiltration with endogenous reinfusion versus acetate-free biofiltration.

    abstract::During hemodialysis, amino acids (AA) are lost in the ultrafiltrate with consequent modification of their plasma profile. The aim of this cross-sectional study was to evaluate intradialytic changes of plasma AA levels during a single session of hemodiafiltration with endogenous reinfusion (HFR) versus acetate-free bio...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000320133

    authors: Borrelli S,Minutolo R,De Nicola L,Zamboli P,Iodice C,De Paola A,De Simone E,Zito B,Guastaferro P,Nigro F,Apperti V,Iulianiello G,Credendino O,Iacono G,Di Serafino A,D'Apice L,Saviano C,Sarti A,Capuano M,Genualdo R,

    更新日期:2010-01-01 00:00:00

  • Peritoneal dialysis in Europe: an analysis of its rise and fall.

    abstract::There is a wide variability in the utilization of peritoneal dialysis throughout Europe that cannot be explained by differences in medical factors alone. Over the last years, the utilization of peritoneal dialysis has even changed in individual countries. The main factors of this variation are not medical, but rather ...

    journal_title:Blood purification

    pub_type: 杂志文章,评审

    doi:10.1159/000089446

    authors: Lameire N,Peeters P,Vanholder R,Van Biesen W

    更新日期:2006-01-01 00:00:00

  • Epidemiology of acute renal failure in ICUs: a multi-center prospective study.

    abstract:BACKGROUND AND AIM:Acute kidney injury (AKI) is a common complication in intensive care units (ICUs). However, its incidence and outcome vary in several studies depending on definitions used or even the geographic origin of the study. We aimed to evaluate the epidemiology of AKI in ICUs in Greece. METHOD:Prospective m...

    journal_title:Blood purification

    pub_type: 杂志文章,多中心研究

    doi:10.1159/000231986

    authors: Andrikos E,Tseke P,Balafa O,Cruz DN,Tsinta A,Androulaki M,Pappas M,Ronco C

    更新日期:2009-01-01 00:00:00

  • Entropy of uremia and dialysis technology.

    abstract::The second law of thermodynamics applies with local exceptions to patient history and therapy interventions. Living things preserve their low level of entropy throughout time because they receive energy from their surroundings in the form of food. They gain their order at the expense of disordering the nutrients they ...

    journal_title:Blood purification

    pub_type: 杂志文章

    doi:10.1159/000345755

    authors: Ronco C

    更新日期:2013-01-01 00:00:00