Combining casein phosphopeptide-amorphous calcium phosphate with fluoride: synergistic remineralization potential of artificially demineralized enamel or not?

abstract：:We explore the use of Monte-Carlo-model-based approaches for the analysis of fluorescence and diffuse reflectance spectra measured ex vivo from breast tissues. These models are used to extract the absorption, scattering, and fluorescence properties of malignant and nonmalignant tissues and to diagnose breast cancer ba...

journal_title：Journal of biomedical optics

authors： Zhu C,Palmer GM,Breslin TM,Harter J,Ramanujam N

更新日期：2008-05-01 00:00:00

abstract：:This study introduces a single-channel optical video stereomicroscope based on a transparent rotating deflector (TRD) for high-resolution and high-magnification stereomicroscopy. The existing stereomicroscopes have some limitations, such as limited resolution and magnification, fixed optical channel, and the necessity...

journal_title：Journal of biomedical optics

authors： Radfar E,Park J,Jung B

更新日期：2016-12-01 00:00:00

abstract：:Focusing light inside highly scattering media is a challenging task in biomedical optical imaging, manipulation, and therapy. A recent invention has overcome this challenge by time reversing ultrasonically encoded diffuse light to an ultrasound-modulated volume inside a turbid medium. In this technique, a photorefract...

journal_title：Journal of biomedical optics

authors： Yang Q,Xu X,Lai P,Xu D,Wang LV

更新日期：2013-11-01 00:00:00

abstract：:Malaria parasites induce morphological, biochemical, and mechanical changes in red blood cells (RBCs). Mechanical variations are closely related to the deformability of individual RBCs. The deformation of various RBCs, including healthy and malaria-infected RBCs (iRBCs), can be directly observed through quantitative p...

journal_title：Journal of biomedical optics

authors： Byeon H,Ha YR,Lee SJ

更新日期：2015-11-01 00:00:00

abstract：:In order to monitor dynamic physiological events in near-real time, a variety of photoacoustic computed tomography (PACT) systems have been developed that can rapidly acquire data. Previously reported studies of dynamic PACT have employed conventional static methods to reconstruct a temporally ordered sequence of imag...

journal_title：Journal of biomedical optics

authors： Wang K,Xia J,Li C,Wang LV,Anastasio MA

更新日期：2014-05-01 00:00:00

abstract：:There are several pathologies whose study and diagnosis is impaired by a relatively small number of documented cases. A practical approach to overcome this obstacle and advance the research in this area consists in employing computer simulations to perform controlled in silico experiments. The results of these experim...

journal_title：Journal of biomedical optics

authors： Baranoski GV,Chen TF,Kimmel BW,Miranda E,Yim D

更新日期：2012-09-01 00:00:00

abstract：:We present the light scattering properties of individual human red blood cells (RBCs). We show that both the RBC static and dynamic scattering signals are altered by adenosine 5'-triphosphate (ATP)-driven membrane metabolic remodeling. To measure the light scattering signal from individual RBCs, we use diffraction pha...

journal_title：Journal of biomedical optics

authors： Park Y,Best-Popescu CA,Dasari RR,Popescu G

更新日期：2011-01-01 00:00:00

abstract：:A Monte-Carlo-based model of fluorescence is developed that is capable of extracting the intrinsic fluorescence properties of tissue, which are independent of the absorption and scattering properties of tissue. This model is flexible in its applicability to different illumination-collection geometries and is also vali...

journal_title：Journal of biomedical optics

authors： Palmer GM,Ramanujam N

更新日期：2008-03-01 00:00:00

abstract：:The absorption coefficient mu(a), scattering coefficient mu(s), and anisotropy factor g of diluted and undiluted human blood (hematocrit 0.84 and 42.1%) are determined under flow conditions in the wavelength range 250 to 1100 nm, covering the absorption bands of hemoglobin. These values are obtained by high precision ...

journal_title：Journal of biomedical optics

authors： Friebel M,Roggan A,Müller G,Meinke M

更新日期：2006-05-01 00:00:00

abstract：SIGNIFICANCE:Visible light optical coherence tomography (OCT) is emerging for spectroscopic and ultrahigh resolution imaging, but challenges remain. Depth-dependent dispersion limits retinal image quality and current correction approaches are cumbersome. Inconsistent group refractive indices during image reconstruction...

journal_title：Journal of biomedical optics

authors： Zhang T,Kho AM,Srinivasan VJ

更新日期：2020-09-01 00:00:00

abstract：:Predicting the distribution of light inside any turbid media, such as biological tissue, requires detailed information about the optical properties of the medium, including the absorption and scattering coefficients and the anisotropy factor. Particularly, in biophotonic applications where photons directly interact wi...

journal_title：Journal of biomedical optics

authors： Azimipour M,Baumgartner R,Liu Y,Jacques SL,Eliceiri K,Pashaie R

更新日期：2014-01-01 00:00:00

abstract：:Optical spectroscopy has shown potential as a real-time, in vivo, diagnostic tool for identifying neoplasia during endoscopy. We present the development of a diagnostic algorithm to classify elastic-scattering spectroscopy (ESS) spectra as either neoplastic or non-neoplastic. The algorithm is based on pattern recognit...

journal_title：Journal of biomedical optics

authors： Rodriguez-Diaz E,Castanon DA,Singh SK,Bigio IJ

更新日期：2011-06-01 00:00:00

abstract：:Optical coherence tomography (OCT) is a potential clinical tool for enamel lesion monitoring. Swept-source OCT findings were compared with cross-sectional nanohardness findings of enamel. Subsurface bovine enamel lesions in three groups were subjected to (1) deionized water (control), (2) phosphoryl oligosaccharide of...

journal_title：Journal of biomedical optics

authors： Mandurah MM,Sadr A,Shimada Y,Kitasako Y,Nakashima S,Bakhsh TA,Tagami J,Sumi Y

更新日期：2013-04-01 00:00:00

abstract：:An adaptive pulse shaper controlled by multiphoton intrapulse interference phase scanning (MIIPS) was used, together with a prism-pair, to measure and cancel high-order phase distortions introduced by a high-numerical-aperture objective and other dispersive elements of a two-photon laser-scanning microscope. The deliv...

journal_title：Journal of biomedical optics

authors： Xi P,Andegeko Y,Pestov D,Lovozoy VV,Dantus M

更新日期：2009-01-01 00:00:00

abstract：:Dispersion encoded full-range (DEFR) frequency-domain optical coherence tomography (FD-OCT) and its enhanced version, fast DEFR, utilize dispersion mismatch between sample and reference arm to eliminate the ambiguity in OCT signals caused by non-complex valued spectral measurement, thereby numerically doubling the usa...

journal_title：Journal of biomedical optics

authors： Wang L,Hofer B,Guggenheim JA,Povazay B

更新日期：2012-07-01 00:00:00

abstract：:The morphogenetic relationship between early patterning and polarity formation is of fundamental interest and remains a controversial issue in preimplantation embryonic development. We use a label-free three-dimensional (3-D) imaging technique of full-field optical coherence tomography (FF-OCT) successfully for the fi...

journal_title：Journal of biomedical optics

authors： Zheng JG,Huo T,Chen T,Wang C,Zhang N,Tian N,Zhao F,Lu D,Chen D,Ma W,Sun JL,Xue P

更新日期：2013-01-01 00:00:00

abstract：:Fourier domain (FD) techniques have increasingly gained attention in optical coherence tomography (OCT). This is primarily due to their demonstrated sensitivity of two to three orders of magnitude over conventional time-domain techniques. FDOCT images are subject to two primary sources of artifacts. First, a complex c...

journal_title：Journal of biomedical optics

authors： Davis AM,Choma MA,Izatt JA

更新日期：2005-11-01 00:00:00

abstract：:Frequency domain optical coherence tomography (FD-OCT), based on an all-reflective high-speed InGaAs spectrometer, operating in the 1050 nm wavelength region for retinal diagnostics, enables high-speed, volumetric imaging of retinal pathologies with greater penetration into choroidal tissue is compared to conventional...

journal_title：Journal of biomedical optics

authors： Povazay B,Hermann B,Unterhuber A,Hofer B,Sattmann H,Zeiler F,Morgan JE,Falkner-Radler C,Glittenberg C,Blinder S,Drexler W

更新日期：2007-07-01 00:00:00

abstract：:Surgical excision of the whole prostate through a radical prostatectomy procedure is part of the standard of care for prostate cancer. Positive surgical margins (cancer cells having spread into surrounding nonresected tissue) occur in as many as 1 in 5 cases and strongly correlate with disease recurrence and the requi...

journal_title：Journal of biomedical optics

authors： Pinto M,Zorn KC,Tremblay JP,Desroches J,Dallaire F,Aubertin K,Marple E,Kent C,Leblond F,Trudel D,Lesage F

更新日期：2019-02-01 00:00:00

abstract：:Polarized Raman spectroscopy allows measurement of molecular orientation and composition and is widely used in the study of polymer systems. Here, we extend the technique to the extraction of quantitative orientation information from bone tissue, which is optically thick and highly turbid. We discuss multiple scatteri...

journal_title：Journal of biomedical optics

authors： Raghavan M,Sahar ND,Wilson RH,Mycek MA,Pleshko N,Kohn DH,Morris MD

更新日期：2010-05-01 00:00:00

abstract：:The present work describes the fabrication and characterization of an optical fiber pH sensor using a sol–gel technique. The sensing head configuration is incorporated using a short section of no-core fiber, coated with tetraethyl orthosilicate and spliced at the end of a single mode fiber with a bulge. Different type...

journal_title：Journal of biomedical optics

authors： Bhardwaj V,Pathak AK,Singh VK

更新日期：2017-05-01 00:00:00

abstract：:Ex vivo human skin has been used extensively for cosmeceutical and drug delivery studies, transplantable skin allografts, or skin flaps. However, it has a half-life of a few days due to ischemic necrosis. Traditional methods of assessing viability can be time-consuming and provide limited metabolic information. Using ...

journal_title：Journal of biomedical optics

authors： Sanchez WY,Prow TW,Sanchez WH,Grice JE,Roberts MS

更新日期：2010-07-01 00:00:00

abstract：:Time-deconvolution of the instrument response from fluorescence lifetime imaging microscopy (FLIM) data is usually necessary for accurate fluorescence lifetime estimation. In many applications, however, the instrument response is not available. In such cases, a blind deconvolution approach is required. An iterative me...

journal_title：Journal of biomedical optics

authors： Campos-Delgado DU,Gutierrez-Navarro O,Arce-Santana ER,Skala MC,Walsh AJ,Jo JA

更新日期：2015-07-01 00:00:00

abstract：:Oxygen plays a very important role in living cells. The intracellular level of oxygen is under tight control, as even a small deviation from normal oxygen level affects major cellular metabolic processes and is likely to result in cellular damage or cell death. This paper describes the use of the oxygen sensitive fluo...

journal_title：Journal of biomedical optics

authors： Asiedu JK,Ji J,Nguyen M,Rosenzweig N,Rosenzweig Z

更新日期：2001-04-01 00:00:00

abstract：:The effect of sampling region size and tissue heterogeneity is examined using fluorescence histogram assessment in a rat prostate tumor model with benzoporphyrin derivative fluorophore. Spatial heterogeneity in the fluorescence signal occurs on both macroscopic and microscopic scales. The periphery of the tumor is mor...

journal_title：Journal of biomedical optics

authors： Pogue BW,Chen B,Zhou X,Hoopes PJ

更新日期：2005-07-01 00:00:00

abstract：:Reduction of optical scattering in turbid biological tissues using nonreactive chemical agents has potential applications for light-based diagnostics and therapeutics. Optical clearing effects by exogenous chemical agents, in particular sugars and sugar alcohols, have been found to be temporary with tissue rehydration...

journal_title：Journal of biomedical optics

authors： Yeh AT,Hirshburg J

更新日期：2006-01-01 00:00:00

abstract：:Fluorescence-guided diagnosis of tumor tissue is in many cases insufficient, because false positive results interfere with the outcome. Improvement through observation of cell metabolism might offer the solution, but needs a detailed understanding of the origin of autofluorescence. With respect to this, spectrally res...

journal_title：Journal of biomedical optics

authors： Rück A,Hauser C,Mosch S,Kalinina S

更新日期：2014-09-01 00:00:00

abstract：:Optical coherence tomography (OCT) can provide new insight into disease progression and therapy by enabling nondestructive, serial imaging of in vivo cancer models. In previous studies, we have shown the utility of endoscopic OCT for identifying adenomas in the azoxymethane-treated mouse model of colorectal cancer and...

journal_title：Journal of biomedical optics

authors： Winkler AM,Rice PF,Drezek RA,Barton JK

更新日期：2010-07-01 00:00:00

abstract：SIGNIFICANCE:The retina is critical for vision, and several diseases may alter its biomechanical properties. However, assessing the biomechanical properties of the retina nondestructively is a challenge due to its fragile nature and location within the eye globe. Advancements in Brillouin spectroscopy have provided the...

journal_title：Journal of biomedical optics

authors： Ambekar YS,Singh M,Scarcelli G,Rueda EM,Hall BM,Poché RA,Larin KV

更新日期：2020-09-01 00:00:00

abstract：:Multiphoton microscopy has evolved into a powerful bioimaging tool in three dimensions. However, the ability to image biological specimens in-depth can be hindered by sample spherical aberration and scattering. These two phenomena can result in the degradation of image resolution and the loss of detected multiphoton s...

journal_title：Journal of biomedical optics

authors： Lo W,Sun Y,Lin SJ,Jee SH,Dong CY

更新日期：2005-05-01 00:00:00