Abstract:
:There are several pathologies whose study and diagnosis is impaired by a relatively small number of documented cases. A practical approach to overcome this obstacle and advance the research in this area consists in employing computer simulations to perform controlled in silico experiments. The results of these experiments, in turn, may be incorporated in the design of differential protocols for these pathologies. Accordingly, in this paper, we investigate the spectral responses of human skin affected by the presence of abnormal amounts of two dysfunctional hemoglobins, methemoglobin and sulfhemoglobin, which are associated with two life-threatening medical conditions, methemoglobinemia and sulfhemoglobinemia, respectively. We analyze the results of our in silico experiments and discuss their potential applications to the development of more effective noninvasive monitoring and differentiation procedures for these medical conditions.
journal_name
J Biomed Optjournal_title
Journal of biomedical opticsauthors
Baranoski GV,Chen TF,Kimmel BW,Miranda E,Yim Ddoi
10.1117/1.JBO.17.9.097005subject
Has Abstractpub_date
2012-09-01 00:00:00pages
97005issue
9eissn
1083-3668issn
1560-2281pii
1358106journal_volume
17pub_type
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