Quantitative assessment of radiation-induced changes of bladder and rectum collagen structure using optical methods.

abstract：:We present the light scattering properties of individual human red blood cells (RBCs). We show that both the RBC static and dynamic scattering signals are altered by adenosine 5'-triphosphate (ATP)-driven membrane metabolic remodeling. To measure the light scattering signal from individual RBCs, we use diffraction pha...

journal_title：Journal of biomedical optics

authors： Park Y,Best-Popescu CA,Dasari RR,Popescu G

更新日期：2011-01-01 00:00:00

abstract：:Fluorescent proteins and dyes are routine tools for biological research to describe the behavior of genes, proteins, and cells, as well as more complex physiological dynamics such as vessel permeability and pharmacokinetics. The use of these probes in whole body in vivo imaging would allow extending the range and scop...

journal_title：Journal of biomedical optics

authors： Favicchio R,Psycharakis S,Schönig K,Bartsch D,Mamalaki C,Papamatheakis J,Ripoll J,Zacharakis G

更新日期：2016-02-01 00:00:00

abstract：:Optical clearing is a well-known phenomenon. It is based on the matching of refractive indices of a bulk material and scattering particles. The same principle is also used in scattering-based optical measurements of different constituents, such as glucose. By registering changes in scattering, it is possible to evalua...

journal_title：Journal of biomedical optics

authors： Kinnunen M,Myllylä R,Vainio S

更新日期：2008-03-01 00:00:00

abstract：:Since 1978 in vitro fertilization (IVF) procedures have resulted in the birth of over 3 million babies. Yet in 2005, IVF procedures had a live birth rate of only 34%, with 32% of these births resulting in multiple pregnancies. These multiple pregnancies were directly attributed to the transfer of multiple embryos to i...

journal_title：Journal of biomedical optics

authors： Warger WC 2nd,Newmark JA,Warner CM,DiMarzio CA

更新日期：2008-05-01 00:00:00

abstract：:The intracellular refractive index is an important parameter that describes the optical density of the cytoplasm and the concentration of the intracellular solutes. The refractive index of adherently grown cells is difficult to access. We present a method in which silica microspheres in living cells are used to determ...

journal_title：Journal of biomedical optics

authors： Przibilla S,Dartmann S,Vollmer A,Ketelhut S,Greve B,von Bally G,Kemper B

更新日期：2012-09-01 00:00:00

abstract：:Traditional white-light and fluorescent imaging techniques provide powerful methods to extract high-resolution information from two-dimensional (2-D) sections, but to retrieve information from a three-dimensional (3-D) volume they require relatively slow scanning methods that result in increased acquisition time. Usin...

journal_title：Journal of biomedical optics

authors： Duocastella M,Sun B,Arnold CB

更新日期：2012-05-01 00:00:00

abstract：:We describe a systematic approach to image, track, and quantify the movements of HIV viruses embedded in human cervical mucus. The underlying motivation for this study is that, in HIV-infected adults, women account for more than half of all new cases and most of these women acquire the infection through heterosexual c...

journal_title：Journal of biomedical optics

authors： Boukari F,Makrogiannis S,Nossal R,Boukari H

更新日期：2016-09-01 00:00:00

abstract：:A compact handpiece combining high resolution fluorescence (HRF) imaging with optical coherence tomography (OCT) was developed to provide real-time assessment of oral lesions. This multimodal imaging device simultaneously captures coregistered en face images with subcellular detail alongside cross-sectional images of ...

journal_title：Journal of biomedical optics

authors： Higgins LM,Pierce MC

更新日期：2014-08-01 00:00:00

abstract：:Noninvasive diagnostic tools, such as Trichoscan®, reflectance confocal microscopy (RCM), and optical coherence tomography (OCT), are efficient methods of hair shaft and growth evaluation. The aim of this study was to carry out a comparative assessment of these three medical procedures by measuring the hair shaft and ...

journal_title：Journal of biomedical optics

authors： Kuck M,Schanzer S,Ulrich M,Garcia Bartels N,Meinke MC,Fluhr J,Krah M,Blume-Peytavi U,Stockfleth E,Lademann J

更新日期：2012-10-01 00:00:00

abstract：:We investigate the relationship between the laser beam at the retina (spot size) and the extent of retinal injury from single ultrashort laser pulses. From previous studies it is believed that the retinal effect of single 3-ps laser pulses should vary in extent and location, depending on the occurrence of laser-induce...

journal_title：Journal of biomedical optics

authors： Roach WP,Cain CP,Narayan DG,Noojin GD,Boppart SA,Birngruber R,Fujimoto JG,Toth CA

更新日期：2004-11-01 00:00:00

abstract：:An evolving area of biomedical research is related to the creation of implantable units that provide various possibilities for imaging, measurement, and the monitoring of a wide range of diseases and intrabody phototherapy. The units can be autonomic or built-in in some kind of clinically applicable implants. Because ...

journal_title：Journal of biomedical optics

authors： Sheinman V,Rudnitsky A,Toichuev R,Eshiev A,Abdullaeva S,Egemkulov T,Zalevsky Z

更新日期：2014-01-01 00:00:00

abstract：:The results of an experimental study of the possibilities of monitoring erbium yttrium aluminum garnet laser-mediated ablation of human epidermis with the use of Fourier transform infrared (FTIR) spectroscopy and spectral polarization techniques are presented. The attenuated total reflection (ATR) method was used for ...

journal_title：Journal of biomedical optics

authors： Sviridov AP,Zimnyakov DA,Sinichkin YP,Butvina LN,Omelchenko AJ,Shakh GS,Bagratashvili VN

更新日期：2004-07-01 00:00:00

abstract：:In near-infrared spectroscopy, concentration changes in oxygenated and deoxygenated hemoglobin are calculated from the changes in the attenuation of the measurement light. This is done by solving a linear equation based on the modified Lambert-Beer law. To solve this equation, we need to know the partial optical pathl...

journal_title：Journal of biomedical optics

authors： Umeyama S,Yamada T

更新日期：2009-05-01 00:00:00

abstract：:Optical coherence tomography (OCT) provides more parameters than pure morphology does. In a recent paper [A. Knuettel and M. Boehlau-Godau, J. Biomed. Opt. 5(1) 83-92 (2000)] we have shown that the refractive index (RI) can be evaluated in a localized manner in skin tissue under in vivo conditions. Based on a theory, ...

journal_title：Journal of biomedical optics

authors： Knüttel A,Bonev S,Knaak W

更新日期：2004-03-01 00:00:00

abstract：:Breast cancer is one of the most common cancers in females. To monitor chemotherapeutic efficacy for breast cancer, medical imaging systems such as x-ray mammography, computed tomography, magnetic resonance imaging, and ultrasound imaging have been used. Currently, it can take up to 3 to 6 weeks to see the tumor respo...

journal_title：Journal of biomedical optics

authors： Lee S,Jeong H,Seong M,Kim JG

更新日期：2017-12-01 00:00:00

abstract：:Sugar-rich diets and poor dental hygiene promote the formation of a biofilm (plaque) that strongly adheres to the dental enamel surface and fosters the evolution of aciduric bacteria. The acid contributes to demineralization of the exterior tooth enamel, which accelerates after the pH drops below a critical value (∼5....

journal_title：Journal of biomedical optics

authors： Sharma M,Graham JY,Walczak PA,Nguyen R,Lee LK,Carson MD,Nelson LY,Patel SN,Xu Z,Seibel EJ

更新日期：2019-01-01 00:00:00

abstract：:Intrauterine photoacoustic and ultrasound imaging are probe-based imaging modalities with translational potential for use in detecting endometrial diseases. This deep-tissue imaging probe design allows for the retrofitting of commercially available endometrial sampling curettes. The imaging probe presented here has a ...

journal_title：Journal of biomedical optics

authors： Miranda C,Barkley J,Smith B

更新日期：2018-04-01 00:00:00

abstract：:Real-time medical imaging systems such as reflectance confocal microscopes and optical coherence microscopes are being tested in multiple-patient and multiple-center clinical trials. The modulation transfer function (MTF) of these systems at any given time influences the image information content and can affect the in...

journal_title：Journal of biomedical optics

authors： Wang Z,Glazowski CE,Zavislan JM

更新日期：2007-09-01 00:00:00

abstract：:Imaging technologies working in the spatial frequency domain are becoming increasingly popular for generating wide-field maps of optical properties, enabling rapid analysis of tissue parameters. While acquisition methods have become faster and are now performing in real-time, processing methods remain slow, precluding...

journal_title：Journal of biomedical optics

authors： Angelo J,Vargas CR,Lee BT,Bigio IJ,Gioux S

更新日期：2016-11-01 00:00:00

abstract：:We report noninvasive, in vivo optical imaging deep within a mouse brain by swept-source optical coherence tomography (SS-OCT), enabled by a 1.3-μm vertical cavity surface emitting laser (VCSEL). VCSEL SS-OCT offers a constant signal sensitivity of 105 dB throughout an entire depth of 4.25 mm in air, ensuring an exten...

journal_title：Journal of biomedical optics

authors： Choi WJ,Wang RK

更新日期：2015-10-01 00:00:00

abstract：:Deep anterior lamellar keratoplasty (DALK) is an emerging surgical technique for the restoration of corneal clarity and vision acuity. The big-bubble technique in DALK surgery is the most essential procedure that includes the air injection through a thin syringe needle to separate the dysfunctional region of the corne...

journal_title：Journal of biomedical optics

authors： Shin S,Bae JK,Ahn Y,Kim H,Choi G,Yoo YS,Joo CK,Moon S,Jung W

更新日期：2017-12-01 00:00:00

abstract：:Optical spectroscopy, imaging, and therapy tissue phantoms must have the scattering and absorption properties that are characteristic of human tissues, and over the past few decades, many useful models have been created. In this work, an overview of their composition and properties is outlined, by separating matrix, s...

journal_title：Journal of biomedical optics

authors： Pogue BW,Patterson MS

更新日期：2006-07-01 00:00:00

abstract：SIGNIFICANCE:Photothermal optical coherence tomography (PT-OCT) has the promise to offer structural images coregistered with chemical composition information, which can offer a significant impact in early detection of diseases such as atherosclerosis. AIM:We take the first step in understanding the relation between PT...

journal_title：Journal of biomedical optics

authors： Salimi M,Villiger M,Tabatabaei N

更新日期：2020-12-01 00:00:00

abstract：:Spectral resolved tissue imaging has a broad range of biomedical applications such as the minimally invasive diagnosis of diseases and the study of wound healing and tissue engineering processes. Two-photon microscopy imaging of endogenous fluorescence has been shown to be a powerful method for the quantification of t...

journal_title：Journal of biomedical optics

authors： Laiho LH,Pelet S,Hancewicz TM,Kaplan PD,So PT

更新日期：2005-03-01 00:00:00

abstract：:Intracellular oxygen concentration is of primary importance in determining numerous physiological and pathological processes in biological systems. In this paper, we describe the application of the oxygen sensing indicator, ruthenium dibipyridine 4-(1"-pyrenyl)-2,2'-bipyridine chloride [Ru(bpy-pyr)(bpy)(2)], for molec...

journal_title：Journal of biomedical optics

authors： Ji J,Rosenzweig N,Jones I,Rosenzweig Z

更新日期：2002-07-01 00:00:00

abstract：:Animal models are widely used to investigate the pathological mechanisms of spinal cord injury (SCI), most commonly in rats. It is well known that compromised blood flow caused by mechanical disruption of the vasculature can produce irreversible damage and cell death in hypoperfused tissue regions and spinal cord tiss...

journal_title：Journal of biomedical optics

authors： Phillips JP,Cibert-Goton V,Langford RM,Shortland PJ

更新日期：2013-03-01 00:00:00

abstract：:Pelvic organ prolapse (POP) occurs when changes to the pelvic organ support structures cause descent or herniation of the pelvic organs into the vagina. Clinical evaluation of POP is a series of manual measurements known as the pelvic organ prolapse quantification (POP-Q) score. However, it fails to identify the mecha...

journal_title：Journal of biomedical optics

authors： Parkinson LA,Gargett CE,Young N,Rosamilia A,Vashi AV,Werkmeister JA,Papageorgiou AW,Arkwright JW

更新日期：2016-12-01 00:00:00

abstract：:We present a simple wide-field imaging technique, called HiLo microscopy, that is capable of producing optically sectioned images in real time, comparable in quality to confocal laser scanning microscopy. The technique is based on the fusion of two raw images, one acquired with speckle illumination and another with st...

journal_title：Journal of biomedical optics

authors： Lim D,Ford TN,Chu KK,Mertz J

更新日期：2011-01-01 00:00:00

abstract：:Fourier transform infrared (FTIR) microspectroscopy has been used to estimate the spatial proteoglycan (PG) and collagen contents in articular cartilage (AC). However, it is not clear whether the results of FTIR analyses are consistent between different species. Our aim was to clarify how three different FTIR PG param...

journal_title：Journal of biomedical optics

authors： Rieppo L,Närhi T,Helminen HJ,Jurvelin JS,Saarakkala S,Rieppo J

更新日期：2013-09-01 00:00:00

abstract：SIGNIFICANCE:In multiphoton microscopy, two-photon excited fluorescence (TPEF) spectra carry valuable information on morphological and functional biological features. For measuring these biomarkers, separation of different parts of the fluorescence spectrum into channels is typically achieved by the use of optical band...

journal_title：Journal of biomedical optics

authors： Meyer BO,Stella MPJ,Holst B,Nielsen BS,Holmstrøm K,Andersen PE,Marti D

更新日期：2020-07-01 00:00:00