Abstract:
:We propose that clusters of closely linked markers, which segregate as stable haplotypes, provide a high potential to solve complex kinship cases. It is known that the X-chromosomal centromere region shows an extremely low degree of recombination. Hence, we focused our interest on the region between 56 and 64 Mb distant from the Xp telomere and considered 6 STRs which are now registered in the Genome Data Base as DXS10161, DXS10159, DXS10162, DXS10163, DXS10164, and DXS10165. All of these markers show a tetranucleotide or pentanucleotide structure and exhibit high or medium polymorphic information content. As a peculiarity, DXS10163 is a combination of a pentanucleotide STR and an 18 bp INDEL polymorphism. We report here the primer sequences, the repeat structures, the allele distributions and parameters of forensic interest for a German population sample.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Edelmann J,Hering S,Augustin C,Kalis S,Szibor Rdoi
10.1007/s00414-009-0328-9subject
Has Abstractpub_date
2010-01-01 00:00:00pages
83-7issue
1eissn
0937-9827issn
1437-1596journal_volume
124pub_type
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-012-0705-7
更新日期:2012-07-01 00:00:00
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pub_type: 杂志文章,实务指引
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更新日期:2019-01-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-018-1863-z
更新日期:2019-07-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
doi:10.1007/s00414-007-0171-9
更新日期:2007-11-01 00:00:00
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更新日期:2013-05-01 00:00:00
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更新日期:2017-03-01 00:00:00
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journal_title:International journal of legal medicine
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journal_title:International journal of legal medicine
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pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00
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journal_title:International journal of legal medicine
pub_type: 杂志文章
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更新日期:2021-01-23 00:00:00
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更新日期:2021-01-01 00:00:00