Cell migration and activated PI3K/AKT-directed elongation in the developing rat Müllerian duct.

abstract：:A fundamental feature of cartilage differentiation in the developing limb is the formation of a prechondrogenic cell condensation. An apparently similar process of prechondrogenic cell aggregation occurs in micromass cultures of limb bud mesenchyme with the formation of cellular aggregates which often differentiate in...

journal_title：Developmental biology

authors： Cottrill CP,Archer CW,Wolpert L

更新日期：1987-08-01 00:00:00

abstract：:Carbohydrate chains on the t12 mutant embryos were analyzed. No abnormalities of the synthesis of the carbohydrate chains were observed in the t12 homozygotes until the late morula stage, when radiolabeled carbohydrate chains were analyzed by Sephadex G-50 column chromatography. Furthermore, polarization of the Con A ...

journal_title：Developmental biology

authors： Iwakura Y,Nozaki M

更新日期：1988-08-01 00:00:00

abstract：:Metamorphosis involves the destruction of larval, the formation of adult and the transformation of larval into adult tissues. In this study, we demonstrate the role of the Drosophila nuclear proteins EAST and Chromator in tissue destruction and remodeling. To better understand the function of east, we performed a yeas...

journal_title：Developmental biology

authors： Wasser M,Bte Osman Z,Chia W

更新日期：2007-07-15 00:00:00

abstract：:Elastic fibers are produced during fetal and neonatal periods, and by maturity elastin expression has ceased. Fetal bovine hyaline chondrocytes acquired an elastogenic phenotype within 24 hr after isolation from the tissue, even though the tissue does not produce elastic fibers or tropoelastin mRNA in vivo. By multipl...

journal_title：Developmental biology

authors： Lee KA,Pierce RA,Davis EC,Mecham RP,Parks WC

更新日期：1994-05-01 00:00:00

abstract：:Embryonic organizers are signaling centers that coordinate developmental events within an embryo. Localized to either an individual cell or group of cells, embryonic organizing activity induces the specification of other cells in the embryo and can influence formation of body axes. In the spiralian Capitella teleta, p...

journal_title：Developmental biology

authors： Lanza AR,Seaver EC

更新日期：2018-03-01 00:00:00

abstract：:During the process of gastrulation in the sea urchin embryo, the vegetal plate invaginates to form the archenteron, a long narrow tube that extends across the blastocoel. Rearrangement of cells within the archenteron is thought to be a key component of the process of archenteron elongation. While these cell rearrangem...

journal_title：Developmental biology

authors： Ingersoll EP,Ettensohn CA

更新日期：1994-06-01 00:00:00

abstract：:This paper reports a preliminary in silico analysis of the sea urchin kinome. The predicted protein kinases in the sea urchin genome were identified, annotated and classified, according to both function and kinase domain taxonomy. The results show that the sea urchin kinome, consisting of 353 protein kinases, is close...

journal_title：Developmental biology

authors： Bradham CA,Foltz KR,Beane WS,Arnone MI,Rizzo F,Coffman JA,Mushegian A,Goel M,Morales J,Geneviere AM,Lapraz F,Robertson AJ,Kelkar H,Loza-Coll M,Townley IK,Raisch M,Roux MM,Lepage T,Gache C,McClay DR,Manning G

更新日期：2006-12-01 00:00:00

abstract：:The notochord is the defining characteristic of the chordate embryo and plays critical roles as a signaling center and as the primitive skeleton. In this study we show that early notochord development in Xenopus embryos is regulated by apoptosis. We find apoptotic cells in the notochord beginning at the neural groove ...

journal_title：Developmental biology

authors： Malikova MA,Van Stry M,Symes K

更新日期：2007-11-15 00:00:00

abstract：:Mutations in the NF1 gene may cause developmental abnormalities and the formation of a variety of tumors of neural crest origin in humans. The NF1 gene codes for a large protein, neurofibromin (nf), which is structurally and functionally related to yeast and human ras-GTPase-activating proteins (ras-GAPs). Recently, t...

journal_title：Developmental biology

authors： Huynh DP,Nechiporuk T,Pulst SM

更新日期：1994-02-01 00:00:00

abstract：:The categorical data set is an important data class in experimental biology and contains data separable into several mutually exclusive categories. Unlike measurement of a continuous variable, categorical data cannot be analyzed with methods such as the Student's t-test. Thus, these data require a different method of ...

journal_title：Developmental biology

authors： Xu B,Feng X,Burdine RD

更新日期：2010-12-01 00:00:00

abstract：:Pericytes heterogeneity is based on their morphology, distribution, and markers. It is well known that pericytes from different organs may have distinct embryonic sources. Yamazaki et al. (2017) using several transgenic mouse model reveal by cell-lineage tracing that pericytes are even more heterogeneous than previous...

journal_title：Developmental biology

authors： Dias Moura Prazeres PH,Sena IFG,Borges IDT,de Azevedo PO,Andreotti JP,de Paiva AE,de Almeida VM,de Paula Guerra DA,Pinheiro Dos Santos GS,Mintz A,Delbono O,Birbrair A

更新日期：2017-07-01 00:00:00

abstract：:We have cloned a member of the fork head/HNF-3 family of transcription factors from the nematode Caenorhabditis elegans. Within the predicted DNA binding domain, this gene, called Ce-fkh-1, is 75-78% identical to the Drosophila fork head and rat liver HNF-3 alpha, beta, and gamma genes. Ce-fkh-1 mRNA is highly enriche...

journal_title：Developmental biology

authors： Azzaria M,Goszczynski B,Chung MA,Kalb JM,McGhee JD

更新日期：1996-09-15 00:00:00

abstract：:Oligodendrocytes are produced from the same region of the ventral spinal cord that earlier generated motor neurons in bird and rodent embryos. Motor neuron and oligodendrocyte precursor cells express Olig genes, which encode basic helix-loop-helix transcription factors that play important roles in the development of b...

journal_title：Developmental biology

authors： Park HC,Mehta A,Richardson JS,Appel B

更新日期：2002-08-15 00:00:00

abstract：:The axonal functions that act in the formation of the neuronal network have been shown to occur in close interdependence with the tissue that surrounds the growing axons. However, little is known about the molecular building blocks underlying axonal functions, although more than 400 axonal proteins have been identifie...

journal_title：Developmental biology

authors： Sonderegger P,Lemkin PF,Lipkin LE,Nelson PG

更新日期：1986-11-01 00:00:00

abstract：:In this paper I sought to determine how the expression of differentiated traits of chick retinal pigmented epithelial (RPE) cells in vitro can be modulated by varying both the biochemical and the spatial complexity, and the mechanical properties, of the growth substratum. I have used glass derivatized with proteins of...

journal_title：Developmental biology

authors： Opas M

更新日期：1989-02-01 00:00:00

abstract：:Two populations of blastomeres become positionally distinct during fourth cleavage in the mouse embryo; the inner cells become enclosed within the embryo and the outer cells form the enclosing layer. The segregation of these two cell populations is important for later development, because it represents the initial ste...

journal_title：Developmental biology

authors： Sutherland AE,Speed TP,Calarco PG

更新日期：1990-01-01 00:00:00

abstract：:A simple assay has been developed to measure cGMP-specific phosphodiesterase (cGPD) activity in crude soluble extracts of amoebae of Dictyostelium discoideum. When amoebae of different wild-type strains were starved on buffered agar, all strains exhibited an 8- to 12-fold increase in cGMP-specific hydrolyzing activity...

journal_title：Developmental biology

authors： Coukell MB,Cameron AM,Pitre CM,Mee JD

更新日期：1984-05-01 00:00:00

abstract：:Completion of cytokinesis, abscission, has been studied little despite the intensive studies of the onset and contractile mechanism of the earlier phases of division. It has been well documented that microtubule (MT) disruption before furrow stimulation prevents furrowing, while MT disruption after furrow stimulation ...

journal_title：Developmental biology

authors： Larkin K,Danilchik MV

更新日期：1999-10-01 00:00:00

abstract：:P19 embryonal carcinoma cells are multipotential stem cells that differentiate into striated muscle as well as some other cell types when aggregated and exposed to dimethyl sulfoxide (DMSO). Immunofluorescence experiments using monospecific antibodies indicated that the majority of muscle cells were mononucleate and c...

journal_title：Developmental biology

authors： Rudnicki MA,Jackowski G,Saggin L,McBurney MW

更新日期：1990-04-01 00:00:00

abstract：:It has been posited that animal development evolved from pre-existing mechanisms for regulating cell differentiation in the single celled and colonial ancestors of animals. Although the progenitors of animals cannot be studied directly, insights into their cell biology may be gleaned from comparisons between animals a...

journal_title：Developmental biology

authors： Dayel MJ,Alegado RA,Fairclough SR,Levin TC,Nichols SA,McDonald K,King N

更新日期：2011-09-01 00:00:00

abstract：:The mammalian kidney consists of an array of tubules connected to a ductal system that collectively function to control water/salt balance and to remove waste from the organisms' circulatory system. During mammalian embryogenesis, three kidney structures form within the intermediate mesoderm. The two most anterior str...

journal_title：Developmental biology

authors： Mugford JW,Sipilä P,Kobayashi A,Behringer RR,McMahon AP

更新日期：2008-07-15 00:00:00

abstract：:The chicken retina is capable of limited regeneration. In response to injury, some Müller glia proliferate and de-differentiate into progenitor cells. However, most of these progenitors fail to differentiate into neurons. The Notch pathway is upregulated during retinal regeneration in both fish and amphibians. Since t...

journal_title：Developmental biology

authors： Hayes S,Nelson BR,Buckingham B,Reh TA

更新日期：2007-12-01 00:00:00

abstract：:The eukaryotic initiation translation factor eIF6 is a highly conserved, essential protein implicated in translation. eIF6 is regulated in vivo by extracellular signals, such as IGF signaling (for a review see Miluzio et al., 2009). In Xenopus, eif6 over-expression causes a delay in eye development (De Marco et al., 2...

journal_title：Developmental biology

authors： De Marco N,Tussellino M,Carotenuto R,Ronca R,Rizzolio S,Biffo S,Campanella C

更新日期：2017-07-01 00:00:00

abstract：:The patterns of myosin heavy chain (MyHC) isoform expression in the embryo and in the adult mouse are reasonably well characterized and quite distinct. However, little is known about the transition between these two states, which involves major decreases and increases in the expression of several MyHC genes. In the pr...

journal_title：Developmental biology

authors： Allen DL,Leinwand LA

更新日期：2001-01-15 00:00:00

abstract：:The developmental events of sporulation and fruiting body formation in the prokaryote Myxococcus xanthus are preceded by a stage of massive cell death. Two phenotypically complementable strains of M. xanthus defective in developmental lysis were identified from a group of conditional sporulation mutants. Mixture of th...

journal_title：Developmental biology

authors： Janssen GR,Dworkin M

更新日期：1985-11-01 00:00:00

abstract：:Activins are members of the TGF-ss superfamily of secreted growth factors that control a diverse array of processes in vertebrates including endocrine function, cell proliferation, differentiation, immune response and wound repair. In Drosophila, the Activin ligand Dawdle (Daw) has been shown to regulate several aspec...

journal_title：Developmental biology

authors： Ellis JE,Parker L,Cho J,Arora K

更新日期：2010-06-15 00:00:00

abstract：:The engrailed gene is well known from its role in segmentation and central nervous system development in a variety of species. In molluscs, however, engrailed is involved in shell formation. So far, it seemed that engrailed had been co-opted uniquely for this particular process in molluscs. Here, we show that, in the ...

journal_title：Developmental biology

authors： Nederbragt AJ,van Loon AE,Dictus WJ

更新日期：2002-06-15 00:00:00

abstract：:We have investigated the regulation of DNA synthesis in the heterokaryons of HL60 human myelomonocytic leukemia cells and NIH3T3 mouse fibroblasts to examine if the differentiated leukemia cells contained a replication inhibiting activity. Cell fusions were performed either by exposing a suspension of mixed cells to a...

journal_title：Developmental biology

authors： Prudovsky IA,Tsong TY

更新日期：1991-04-01 00:00:00

abstract：:Mammalian eggs remain arrested at metaphase of the second meiotic division (metII) for an indeterminate time before fertilization. During this period, which can last several hours, the continued attachment of sister chromatids is thought to be achieved by inhibition of the protease separase. Separase is known to be in...

journal_title：Developmental biology

authors： Nabti I,Reis A,Levasseur M,Stemmann O,Jones KT

更新日期：2008-09-15 00:00:00

abstract：:The hox genes play a central role in organogenesis and are implicated in the formation of hematopoietic stem cells (HSCs). The cdx genes encode homeodomain transcription factors that act as master regulators of the hox genes. In zebrafish, mutations in cdx4 cause a severe, but not complete, deficit in embryonic blood ...

journal_title：Developmental biology

authors： Davidson AJ,Zon LI

更新日期：2006-04-15 00:00:00