DNA microarray technology in dermatology.

abstract：:Safety remains paramount to the clinical utility of a therapy. Evaluation of safety is an ongoing process that does not end when a therapy becomes commercially available. This article reviews recent data pertaining to the safety profile of two therapeutic classes widely used in the treatment of psoriasis: inhibitors o...

journal_title：Seminars in cutaneous medicine and surgery

authors： Leonardi CL

更新日期：2014-06-01 00:00:00

abstract：:The techniques of noninvasive facial rejuvenation are forever being redefined and improved. This article will review historical as well as present approaches to resurfacing, discussing the nonablative tools that can complement resurfacing procedures. Current thoughts on the pre- and postoperative care of resurfacing p...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kleinerman R,Eisen DB,Kilmer SL,Ibrahimi OA

更新日期：2013-03-01 00:00:00

abstract：:The history of burn scars can best be found in military medical history. The care of wounded soldiers documented in the Illiad reflected the trauma of the weapons of war, arrow, spear, sword, and ax. The introduction of gunpowder in the 14th century, increasingly sophisticated explosives, and in modern times, petroleu...

journal_title：Seminars in cutaneous medicine and surgery

authors： Petro JA

更新日期：2015-03-01 00:00:00

abstract：:Ustekinumab is an interleukin-12/23 inhibitor used for the treatment of moderate-to-severe psoriasis. Here, we review new evidence since ustekinumab was licensed for relative efficacy in comparison with other biologic therapies from head-to-head randomized controlled trials and network meta-analyses for the treatment ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Yiu ZZ,Warren RB

更新日期：2018-09-01 00:00:00

abstract：:Perioral dermatitis is a unique skin disorder of childhood. Its exact origin is unknown; it is probably an idiosyncratic response to exogenous factors such as the use of a topical fluorinated corticosteroid or other substances on the face. It is uncommon but not rare. The age of affected children has ranged from 7 mon...

journal_title：Seminars in cutaneous medicine and surgery

authors： Laude TA,Salvemini JN

更新日期：1999-09-01 00:00:00

abstract：:Mycosis fungoides is a peripheral non-Hodgkin's T-cell neoplastic process, representing the most common type of primary cutaneous malignant lymphoma. Neoplastic lesions classically show skin predilection and characteristic clinical and histologic features in patch, plaque, and tumor stages. In addition, several clinic...

journal_title：Seminars in cutaneous medicine and surgery

authors： Howard MS,Smoller BR

更新日期：2000-06-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a complex dermatological disease characterized by recurrent painful nodules and suppuration in areas such as the axilla and groin. The disease is poorly understood and treatment is not satisfactory. In October 2016, the Canadian and United States Hidradenitis Suppurativa Foundations or...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hoffman LK,Ghias MH,Garg A,Hamzavi IH,Alavi A,Lowes MA

更新日期：2017-06-01 00:00:00

abstract：:Psoriasis is now recognized as an immunologically mediated systemic disease that may be expressed in cutaneous and joint symptoms. Medications that were once thought to control psoriasis by reducing keratinocyte proliferation are now known to act on immunologic pathways. In recent years, the emerging understanding of ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Gordon KB,Strober BE

更新日期：2014-03-01 00:00:00

abstract：:Dermatologic manifestations are among the most common signs of systemic lupus erythematosus (SLE). The Hopkins Lupus Cohort study is a prospective study in which patients with SLE are seen on a quarterly basis for measurement of disease activity, laboratory tests, and assessment of morbidity and quality of life. This ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Petri M

更新日期：1998-09-01 00:00:00

abstract：:Soft tissue augmentation has become increasingly important as more individuals seek aesthetic improvement without major surgical procedures. The choice of an appropriate subcutaneous implant, whether solid or injectable, requires a thorough understanding of the materials available. This review of the literature addres...

journal_title：Seminars in cutaneous medicine and surgery

authors： Krauss MC

更新日期：1999-06-01 00:00:00

abstract：:Among the newer medications for treating psoriasis are the interleukin-17A inhibitor secukinumab and the phosphodiesterase 4 inhibitor apremilast. Secukinumab offers a level of efficacy greater than that of the tumor necrosis factor-α inhibitor adalimumab. Apremilast is associated with lower levels of efficacy than th...

journal_title：Seminars in cutaneous medicine and surgery

authors： Strober BE

更新日期：2016-06-01 00:00:00

abstract：:This review highlights important considerations in obtaining good skin biopsy specimens to optimize results of direct immunofluorescence (IF) studies and also summarizes the various patterns of cutaneous IF deposition and their associated diagnoses. IF findings of immunobullous diseases, lupus erythematosus, vasculiti...

journal_title：Seminars in cutaneous medicine and surgery

authors： Morrison LH

更新日期：1999-03-01 00:00:00

abstract：:The last decade has witnessed a significant advance in the management of refractory moderate-to-severe psoriasis. This advance is the introduction of biological therapies to clinical practice. Three classes of biological therapies have been used. Of the first 2 classes to be introduced, the T-cell inhibitors and tumor...

journal_title：Seminars in cutaneous medicine and surgery

authors： Warren RB,Griffiths CE

更新日期：2010-03-01 00:00:00

abstract：:Electronic billing systems make dermatology practices more efficient and productive. The decision to purchase and install such a system, however, involves a significant amount of time and is often accompanied by many mistakes. This article presents errors commonly made in the evaluation and purchase process and offers...

journal_title：Seminars in cutaneous medicine and surgery

authors： Dinehart S

更新日期：2000-09-01 00:00:00

abstract：:This review highlights melanoma trends observed among African-, Asian-, Latino- and Native-American populations. Melanoma is the most lethal form of skin cancer, accounting for about 75% of all skin cancer deaths. Generally, incidence rates increase with age, peak after age 40, and are greater in men than women. Howev...

journal_title：Seminars in cutaneous medicine and surgery

authors： Shoo BA,Kashani-Sabet M

更新日期：2009-06-01 00:00:00

abstract：:The influences of information technology have touched almost all aspects of our lives, and health care delivery has been no exception. Law, policy, and regulation have driven the adoption of electronic medical records, particularly over the past decade, driving fundamental changes to the practice of medicine in genera...

journal_title：Seminars in cutaneous medicine and surgery

authors： Park AJ,Maruther MK,Swerlick RA

更新日期：2019-03-01 00:00:00

abstract：:Stromal relationships are crucial to metastatic spread of solid malignancies. Some aspects of this stroma interaction are obviously associated with particular morphological features, which may carry prognostic significance. In cutaneous melanoma, level of invasion, arrangement of cells (horizontal or vertical growth p...

journal_title：Seminars in cutaneous medicine and surgery

authors： Smolle J,Hofmann-Wellenhof R,Fink-Puches R

更新日期：1996-12-01 00:00:00

abstract：:Deep morphea encompasses a variety of clinical entities in which inflammation and sclerosis are found in the deep dermis, panniculus, fascia, or superficial muscle. Morphea profunda, eosinophilic fasciitis, and disabling pansclerotic morphea of children are included in this group, but overlapping of the extent and dep...

journal_title：Seminars in cutaneous medicine and surgery

authors： Bielsa I,Ariza A

更新日期：2007-06-01 00:00:00

abstract：:"Venous disease consists of a spectrum with significant medical and economic morbidities. For lack of exposure, however, it is a poorly understood subject. The evaluation and approach to diagnosing venous disease requires a firm understanding of venous anatomy and pathophysiology. With a targeted history and physical,...

journal_title：Seminars in cutaneous medicine and surgery

authors： Nguyen TH

更新日期：2005-12-01 00:00:00

abstract：:Dermoscopy increases the clinician's diagnostic accuracy by as much as 30% over that of unaided visual clinical inspection alone and has been confirmed in 3 separate evidence-based publications using a meta-analysis of the literature. It can be viewed as an in vivo bridge between clinical morphology and histopathology...

journal_title：Seminars in cutaneous medicine and surgery

authors： Braun RP,Rabinovitz H,Tzu JE,Marghoob AA

更新日期：2009-09-01 00:00:00

abstract：:The development of fractional photothermolysis has revolutionized the treatment of skin scarring, rejuvenation, and tightening. By creating targeted microthermal zones and leaving surrounding tissue intact, this concept has provided the field with efficacious results, with less downtime and a better safety profile. Th...

journal_title：Seminars in cutaneous medicine and surgery

authors： Connolly D,Schilling L,Saedi N

更新日期：2017-12-01 00:00:00

abstract：:The development of fractional photothermolysis is a milestone in the history of laser technology and cutaneous resurfacing. Based on the concept that skin is treated in a fractional manner, where narrow cylinders of tissue are thermally heated and normal adjacent skin is left unaffected, the fractional devices have sh...

journal_title：Seminars in cutaneous medicine and surgery

authors： Saedi N,Jalian HR,Petelin A,Zachary C

更新日期：2012-06-01 00:00:00

abstract：:Cellulite is a condition that affects the vast majority of women. Although it is of no danger to one's overall health, cellulite can be psychosocially debilitating. Consequently, much research has been devoted to understanding cellulite and its etiopathogenesis. With additional insights into the underlying causes of i...

journal_title：Seminars in cutaneous medicine and surgery

authors： Green JB,Cohen JL,Kaufman J,Metelitsa AI,Kaminer MS

更新日期：2015-09-01 00:00:00

abstract：:Bathing and moisturization to control dryness, applications of topical anti-inflammatory agents (including corticosteroids and calcineurin inhibitors [TCIs]) to control flares, minimization of the risk for infection, and relief of pruritus are the cornerstones of effective therapy for atopic dermatitis. Education of p...

journal_title：Seminars in cutaneous medicine and surgery

authors： Paller AS,Simpson EL,Eichenfield LF,Ellis CN,Mancini AJ

更新日期：2012-09-01 00:00:00

abstract：:The intraepidermal vesiculobullous disorders constitute a wide variety of pathogenically unrelated disorders that share in common the formation of cleft or bullae formation within the epithelium. The etiologic, pathogenic, clinical and, in particular, the histopathologic attributes of the most important intraepidermal...

journal_title：Seminars in cutaneous medicine and surgery

authors： Cassandra M,Morgan M

更新日期：2004-03-01 00:00:00

abstract：:Nonsurgical procedures have become very popular for the rejuvenation of the aging face. Trends now are for less invasive procedures as well as for more preventative intervention to slow the damage from ultraviolet light and environmental factors, as well as from intrinsic aging. The goal of these procedures is to elim...

journal_title：Seminars in cutaneous medicine and surgery

authors： Lupo MP

更新日期：2006-09-01 00:00:00

abstract：:Cellulite is a common dermatologic condition and frequent cause of cosmetic concern among women. This paper aims to update what is known about the pathogenesis of cellulite and reviews targeted treatment modalities that address its underlying components of microvascular dysfunction, endocrine-mediated inflammation, an...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hogan S,Velez MW,Kaminer MS

更新日期：2018-12-01 00:00:00

abstract：:Medical imaging has dramatically transformed the practice of medicine, especially the field of dermatology. Imaging is used to facilitate the transfer of information between providers, document cutaneous disease, assess response to therapy, and plays a crucial role in monitoring and diagnosing skin cancer. Advancement...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hibler BP,Qi Q,Rossi AM

更新日期：2016-03-01 00:00:00

abstract：:There are many hair disorders, all of which involve alterations in normal hair biology. Essentially, hair disorders involve changes to hair fiber caliber, density per unit area, and/or the duration of anagen and telogen in the hair growth cycle. Hair disorders may be triggered by inflammation, genetics, the environmen...

journal_title：Seminars in cutaneous medicine and surgery

authors： Chu TW,Santos L,McElwee KJ

更新日期：2015-06-01 00:00:00

abstract：:The use of video in the informed consent process has been well documented in the literature to improve patient satisfaction, understanding, comprehension, and to decrease anxiety. At the MD Anderson Mohs Surgery Unit, we use high-definition (HD) audiovisual (AV) modules to assist with the delivery of informed consent ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Migden M,Chavez-Frazier A,Nguyen T

更新日期：2008-03-01 00:00:00