When to request immunofluorescence: practical hints.

abstract：:The history of resurfacing procedures used to treat the aging face is reviewed, and the place of laser resurfacing within this context is described. The changing medical reimbursement system and desire by "baby boomers" to maintain a youthful image have driven the technical development of laser resurfacing. Medical ma...

journal_title：Seminars in cutaneous medicine and surgery

authors： Roenigk HH Jr

更新日期：1996-09-01 00:00:00

abstract：:Effective antimicrobials are critical in controlling one of the most common conditions encountered in medicine, namely, skin and skin structure infections. Unfortunately, the identification of appropriate and novel antimicrobials is continually challenged by the emergence of antimicrobial resistance among bacteria, fu...

journal_title：Seminars in cutaneous medicine and surgery

authors： Yang A,Kerdel FA

更新日期：2006-06-01 00:00:00

abstract：:Melanoma is a particularly aggressive type of skin cancer, and its incidence has been increasing steadily since the 1970s. This article will review the extensive epidemiologic data demonstrating that ultraviolet radiation (UVR) exposure, from the sun or artificial tanning beds, is the most important environmental risk...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kanavy HE,Gerstenblith MR

更新日期：2011-12-01 00:00:00

abstract：:Nonsurgical procedures have become very popular for the rejuvenation of the aging face. Trends now are for less invasive procedures as well as for more preventative intervention to slow the damage from ultraviolet light and environmental factors, as well as from intrinsic aging. The goal of these procedures is to elim...

journal_title：Seminars in cutaneous medicine and surgery

authors： Lupo MP

更新日期：2006-09-01 00:00:00

abstract：:Studies of the prevalence of atopic dermatitis (AD) have provided insights into associated environmental risk factors, demonstrating the complex interactions between the presence of filaggrin (FLG) gene defects and environment. Among other important findings is that elevated transepidermal water loss (TEWL) in newborn...

journal_title：Seminars in cutaneous medicine and surgery

authors： Simpson EL Md McR,Irvine AD Md,Eichenfield LF Md,Friedlander SF Md

更新日期：2016-06-01 00:00:00

abstract：:Stromal relationships are crucial to metastatic spread of solid malignancies. Some aspects of this stroma interaction are obviously associated with particular morphological features, which may carry prognostic significance. In cutaneous melanoma, level of invasion, arrangement of cells (horizontal or vertical growth p...

journal_title：Seminars in cutaneous medicine and surgery

authors： Smolle J,Hofmann-Wellenhof R,Fink-Puches R

更新日期：1996-12-01 00:00:00

abstract：:The development of fractional photothermolysis is a milestone in the history of laser technology and cutaneous resurfacing. Based on the concept that skin is treated in a fractional manner, where narrow cylinders of tissue are thermally heated and normal adjacent skin is left unaffected, the fractional devices have sh...

journal_title：Seminars in cutaneous medicine and surgery

authors： Saedi N,Jalian HR,Petelin A,Zachary C

更新日期：2012-06-01 00:00:00

abstract：:Lasers frequently are used by dermatologists for their multiple aesthetic applications, but they also can be used to treat a variety of medical dermatology conditions. Conditions such as acne vulgaris, psoriasis, and vitiligo can all be successfully treated with laser, thereby providing the patient with additional the...

journal_title：Seminars in cutaneous medicine and surgery

authors： Railan D,Alster TS

更新日期：2008-12-01 00:00:00

abstract：:Oral mucosal bullous/desquamative/ulcerative diseases involve immunopathological mechanisms that account for loss of adhesion between contiguous keratinocytes or to structures within the basal lamina. Some are antibody mediated, in which specific adhesion molecules of the desmosome, hemidesmosome, and basement membran...

journal_title：Seminars in cutaneous medicine and surgery

authors： Eversole LR

更新日期：1997-12-01 00:00:00

abstract：:Immunotherapy for the treatment of advanced melanoma has become a primary treatment in the clinic. Current therapies include systemic cytokines, immune checkpoint inhibitors, and localized intratumoral therapies. Checkpoint inhibitors block natural pathways that dampen or inhibit an immune response to stimulus. These ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Cuevas LM,Daud AI

更新日期：2018-06-01 00:00:00

abstract：:The history of burn scars can best be found in military medical history. The care of wounded soldiers documented in the Illiad reflected the trauma of the weapons of war, arrow, spear, sword, and ax. The introduction of gunpowder in the 14th century, increasingly sophisticated explosives, and in modern times, petroleu...

journal_title：Seminars in cutaneous medicine and surgery

authors： Petro JA

更新日期：2015-03-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic, pruritic, inflammatory skin condition that is associated with immune dysregulation and epidermal barrier dysfunction. The imbalance of the Th2 and Th1 pathways and their associated cytokines in AD presents as one facet of the pathogenic mechanisms. Changes in the T-cell populations...

journal_title：Seminars in cutaneous medicine and surgery

authors： Harskamp CT,Armstrong AW

更新日期：2013-09-01 00:00:00

abstract：:"Venous disease consists of a spectrum with significant medical and economic morbidities. For lack of exposure, however, it is a poorly understood subject. The evaluation and approach to diagnosing venous disease requires a firm understanding of venous anatomy and pathophysiology. With a targeted history and physical,...

journal_title：Seminars in cutaneous medicine and surgery

authors： Nguyen TH

更新日期：2005-12-01 00:00:00

abstract：:Soft tissue augmentation has become increasingly important as more individuals seek aesthetic improvement without major surgical procedures. The choice of an appropriate subcutaneous implant, whether solid or injectable, requires a thorough understanding of the materials available. This review of the literature addres...

journal_title：Seminars in cutaneous medicine and surgery

authors： Krauss MC

更新日期：1999-06-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in MCC has escalated. Recent effort has broadened our breadth of knowledge regardi...

journal_title：Seminars in cutaneous medicine and surgery

authors： Wang TS,Byrne PJ,Jacobs LK,Taube JM

更新日期：2011-03-01 00:00:00

abstract：:Cutaneous infections are common in dermatology. They occur in all populations and all ages. This review will focus on 3 emerging infections encountered by dermatologists; community-acquired methicillin-resistant Staphylococcus aureus, Epstein-Barr virus infections, and the atypical mycobacterial infections. The backgr...

journal_title：Seminars in cutaneous medicine and surgery

authors： Jackson JM

更新日期：2006-12-01 00:00:00

abstract：:Hair disorders include hair loss, increased hair growth, and hair structure defects with increased breakage, as well as unacceptable cosmetic appearance, such as reduced shine, strength, curliness, and elasticity. It is the task of the dermatologist to choose the right diagnostic tool depending on the suspected clinic...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hillmann K,Blume-Peytavi U

更新日期：2009-03-01 00:00:00

abstract：:Idiosyncratic reactions (type B) are a major complication of drug therapy, because they are related to both the drug and to individual factors in the host. In comparison with other organs, the skin is quite frequently a target of allergic reactions, which are mainly elicited by small molecular weight compounds. This i...

journal_title：Seminars in cutaneous medicine and surgery

authors： Merk HF,Hertl M

更新日期：1996-12-01 00:00:00

abstract：:Medical imaging has dramatically transformed the practice of medicine, especially the field of dermatology. Imaging is used to facilitate the transfer of information between providers, document cutaneous disease, assess response to therapy, and plays a crucial role in monitoring and diagnosing skin cancer. Advancement...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hibler BP,Qi Q,Rossi AM

更新日期：2016-03-01 00:00:00

abstract：:In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional gro...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kunz M

更新日期：2008-03-01 00:00:00

abstract：:The goal of treating the aging face is to restore facial balance and modify shadows. A facial evaluation should focus on areas of volume loss and opportunities to use neuromodulators (eg, botulinum toxin A) and the use of fillers. A thorough understanding of facial anatomy, including muscles, nerves, bone, and fat pad...

journal_title：Seminars in cutaneous medicine and surgery

authors： Solish N

更新日期：2016-06-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic skin condition affecting children and adults, with a significant negative impact on patient and caregiver quality of life (QOL). Although effective treatments for AD are available, outcomes are often limited by poor adherence to treatment plans. Effective patient and caregiver educa...

journal_title：Seminars in cutaneous medicine and surgery

authors： LeBovidge J,Borok J,Udkoff J,Yosipovitch G,Eichenfield LF

更新日期：2017-09-01 00:00:00

abstract：:Skin cancers are the most common form of malignancy. Early diagnosis and treatment provides the best chance for survival and reduced morbidity. However, some patients have recurrent or resistant lesions. In patients with basal cell carcinoma (BCC), prognosis is relatively good for all four types of lesions (superficia...

journal_title：Seminars in cutaneous medicine and surgery

authors： Marghoob AA

更新日期：2011-12-01 00:00:00

abstract：:Mycosis fungoides is a peripheral non-Hodgkin's T-cell neoplastic process, representing the most common type of primary cutaneous malignant lymphoma. Neoplastic lesions classically show skin predilection and characteristic clinical and histologic features in patch, plaque, and tumor stages. In addition, several clinic...

journal_title：Seminars in cutaneous medicine and surgery

authors： Howard MS,Smoller BR

更新日期：2000-06-01 00:00:00

abstract：:The term "epidermal nevus syndrome" (ENS) has been used to describe the association of epidermal hamartomas and extra-cutaneous abnormalities. Epidermal nevi follow the lines of Blaschko. The majority of the extra-cutaneous manifestations involve the brain, eye, and skeletal systems. Several subsets with characteristi...

journal_title：Seminars in cutaneous medicine and surgery

authors： Sugarman JL

更新日期：2007-12-01 00:00:00

abstract：:Cutaneous fibrosis is an integral component of a variety of human disorders including keloids, hypertrophic scar, and most notably, scleroderma. Each has its own etiology and unique clinical characteristics, but all involve the dysregulation of connective tissue metabolism, in particular, the activation of dermal fibr...

journal_title：Seminars in cutaneous medicine and surgery

authors： Liu B,Connolly MK

更新日期：1998-03-01 00:00:00

abstract：:The use of video in the informed consent process has been well documented in the literature to improve patient satisfaction, understanding, comprehension, and to decrease anxiety. At the MD Anderson Mohs Surgery Unit, we use high-definition (HD) audiovisual (AV) modules to assist with the delivery of informed consent ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Migden M,Chavez-Frazier A,Nguyen T

更新日期：2008-03-01 00:00:00

abstract：:Topical retinoic acid was introduced for acne treatment three decades ago. Since that time, researchers have discovered thousands of retinoids, originally defined as chemical analogs of vitamin A. After the identification of nuclear retinoid receptors in 1987, the definition of this class expanded to include molecules...

journal_title：Seminars in cutaneous medicine and surgery

authors： Bershad S

更新日期：2001-09-01 00:00:00

abstract：:The ascomycin macrolactam derivative pimecrolimus (Elidel, SDZ ASM 981; Novartis Pharma AG, Basel Switzerland) is a cell-selective inhibitor of inflammatory cytokines specifically developed for the treatment of inflammatory skin diseases, such as atopic dermatitis, allergic contact dermatitis, irritant contact dermati...

journal_title：Seminars in cutaneous medicine and surgery

authors： Stuetz A,Grassberger M,Meingassner JG

更新日期：2001-12-01 00:00:00

abstract：:Cutaneous B-cell lymphomas (CBCLs) are a heterogeneous group of diseases that can have variable presentations, prognoses, and treatments. The proper identification of a CBCL hinges on proper histopathologic and clinical evaluation. Comprising 25% to 30% of the primary cutaneous lymphomas, incident cases of CBCL are ra...

journal_title：Seminars in cutaneous medicine and surgery

authors： Chen ST,Barnes J,Duncan L

更新日期：2018-03-01 00:00:00