Abstract：
:Among the newer medications for treating psoriasis are the interleukin-17A inhibitor secukinumab and the phosphodiesterase 4 inhibitor apremilast. Secukinumab offers a level of efficacy greater than that of the tumor necrosis factor-α inhibitor adalimumab. Apremilast is associated with lower levels of efficacy than the biologic therapies for psoriasis. Apremilast may cause diarrhea and nausea and is associated with weight loss and rare instances of depression. Semin Cutan Med Surg 35(supp4):S71-S73.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Strober BEdoi
10.12788/j.sder.2016.020subject
Has Abstractpub_date
2016-06-01 00:00:00pages
S71-S73issue
4Seissn
1085-5629issn
1558-0768journal_volume
35pub_type
杂志文章abstract：:Soft tissue augmentation has become increasingly important as more individuals seek aesthetic improvement without major surgical procedures. The choice of an appropriate subcutaneous implant, whether solid or injectable, requires a thorough understanding of the materials available. This review of the literature addres...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(99)80036-4
更新日期：1999-06-01 00:00:00
abstract：:Cutaneous B-cell lymphomas (CBCLs) are a heterogeneous group of diseases that can have variable presentations, prognoses, and treatments. The proper identification of a CBCL hinges on proper histopathologic and clinical evaluation. Comprising 25% to 30% of the primary cutaneous lymphomas, incident cases of CBCL are ra...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2018.014
更新日期：2018-03-01 00:00:00
abstract：:Medical imaging has dramatically transformed the practice of medicine, especially the field of dermatology. Imaging is used to facilitate the transfer of information between providers, document cutaneous disease, assess response to therapy, and plays a crucial role in monitoring and diagnosing skin cancer. Advancement...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2016.001
更新日期：2016-03-01 00:00:00
abstract：:One of the most interesting medical conditions that now afflicts the baby boomer generation is photoaging. Clinical signs of photoaging of the skin include rhytids, lentigines, keratoses, telangiectasia, loss of translucency, loss of elasticity, and sallow color. A systematic classification of patient photoaging types...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(96)80003-4
更新日期：1996-09-01 00:00:00
abstract：:Bathing and moisturization to control dryness, applications of topical anti-inflammatory agents (including corticosteroids and calcineurin inhibitors [TCIs]) to control flares, minimization of the risk for infection, and relief of pruritus are the cornerstones of effective therapy for atopic dermatitis. Education of p...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2012.07.004
更新日期：2012-09-01 00:00:00
abstract：:In 1996, oral terbinafine joined itraconazole and fluconazole on the short list of systemic medications that could be used to treat onychomycosis (although fluconazole was not approved for this indication by the US Food and Drug Administration [FDA], it was commonly used for this purpose). In 1999, ciclopirox was the ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2016.009
更新日期：2016-03-01 00:00:00
abstract：:This review highlights important considerations in obtaining good skin biopsy specimens to optimize results of direct immunofluorescence (IF) studies and also summarizes the various patterns of cutaneous IF deposition and their associated diagnoses. IF findings of immunobullous diseases, lupus erythematosus, vasculiti...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(99)80006-6
更新日期：1999-03-01 00:00:00
abstract：:Superficial chemical peels and microdermabrasion are used for many dermatologic conditions. A common condition treated with these modalities is acne vulgaris. In this review, we discuss the theory behind the technique of these procedures and describe the application and complications of each of these procedures in the...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2008.06.003
更新日期：2008-09-01 00:00:00
abstract：:Cellulite is a common dermatologic condition and frequent cause of cosmetic concern among women. This paper aims to update what is known about the pathogenesis of cellulite and reviews targeted treatment modalities that address its underlying components of microvascular dysfunction, endocrine-mediated inflammation, an...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2018.056
更新日期：2018-12-01 00:00:00
abstract：:Prognosis and survival for patients diagnosed with melanoma depends on a number of interrelated factors, including histological, clinical, immunologic, and surgical parameters. Tumor thickness and depth of invasion is the most important prognostic factor, and helps to guide treatment and management plans. Besides tumo...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(97)80005-3
更新日期：1997-06-01 00:00:00
abstract：:Effective antimicrobials are critical in controlling one of the most common conditions encountered in medicine, namely, skin and skin structure infections. Unfortunately, the identification of appropriate and novel antimicrobials is continually challenged by the emergence of antimicrobial resistance among bacteria, fu...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2006.04.006
更新日期：2006-06-01 00:00:00
abstract：:The term "epidermal nevus syndrome" (ENS) has been used to describe the association of epidermal hamartomas and extra-cutaneous abnormalities. Epidermal nevi follow the lines of Blaschko. The majority of the extra-cutaneous manifestations involve the brain, eye, and skeletal systems. Several subsets with characteristi...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2008.03.006
更新日期：2007-12-01 00:00:00
abstract：:Propionibacterium acnes is a key pathogenic factor in the development of acne. Antibiotics are the first choice of treatment for mild-to-moderate, mixed, papular/pustular, and moderate nodular acne, and an alternative choice in severe, nodular/conglobate acne. The emergence of resistance to the currently available ant...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2016.031
更新日期：2016-06-01 00:00:00
abstract：:Nonpharmacologic management of psychodermatologic conditions includes both structured and unstructured interventions that may ameliorate skin disorders, reduce psychological distress, and improve the functional status of the affected individual. Nonpharmacologic techniques are often referred to as psychocutaneous inte...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.0011
更新日期：2013-06-01 00:00:00
abstract：:Immunotherapy for the treatment of advanced melanoma has become a primary treatment in the clinic. Current therapies include systemic cytokines, immune checkpoint inhibitors, and localized intratumoral therapies. Checkpoint inhibitors block natural pathways that dampen or inhibit an immune response to stimulus. These ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2018.028
更新日期：2018-06-01 00:00:00
abstract：:The ascomycin macrolactam derivative pimecrolimus (Elidel, SDZ ASM 981; Novartis Pharma AG, Basel Switzerland) is a cell-selective inhibitor of inflammatory cytokines specifically developed for the treatment of inflammatory skin diseases, such as atopic dermatitis, allergic contact dermatitis, irritant contact dermati...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1053/sder.2001.29066
更新日期：2001-12-01 00:00:00
abstract：:Melanoma is a particularly aggressive type of skin cancer, and its incidence has been increasing steadily since the 1970s. This article will review the extensive epidemiologic data demonstrating that ultraviolet radiation (UVR) exposure, from the sun or artificial tanning beds, is the most important environmental risk...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2011.08.003
更新日期：2011-12-01 00:00:00
abstract：:The term bed bug is applied to 2 species of genus Cimex: lectularius describes the common or temperate bed bug, and hemipterus its tropical cousin. Cimex lectularius is aptly named; its genus and species derive from the Latin words for bug and bed, respectively. Though the tiny pest is receiving increased public atten...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.0106
更新日期：2014-09-01 00:00:00
abstract：:Hair shaft abnormalities are fascinating and can provide a diagnostic challenge. Current knowledge of structural changes in hair has been amplified by scanning and transmission electron microscopy (SEM and TEM). Dermatologists using the light microscope and polarization in the office can diagnose the great majority of...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2006.01.004
更新日期：2006-03-01 00:00:00
abstract：:Electronic billing systems make dermatology practices more efficient and productive. The decision to purchase and install such a system, however, involves a significant amount of time and is often accompanied by many mistakes. This article presents errors commonly made in the evaluation and purchase process and offers...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(00)80025-5
更新日期：2000-09-01 00:00:00
abstract：:The influences of information technology have touched almost all aspects of our lives, and health care delivery has been no exception. Law, policy, and regulation have driven the adoption of electronic medical records, particularly over the past decade, driving fundamental changes to the practice of medicine in genera...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2019.005
更新日期：2019-03-01 00:00:00
abstract：:The use of video in the informed consent process has been well documented in the literature to improve patient satisfaction, understanding, comprehension, and to decrease anxiety. At the MD Anderson Mohs Surgery Unit, we use high-definition (HD) audiovisual (AV) modules to assist with the delivery of informed consent ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.1016/j.sder.2008.02.001
更新日期：2008-03-01 00:00:00
abstract：:The last decade has witnessed a significant advance in the management of refractory moderate-to-severe psoriasis. This advance is the introduction of biological therapies to clinical practice. Three classes of biological therapies have been used. Of the first 2 classes to be introduced, the T-cell inhibitors and tumor...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2010.02.004
更新日期：2010-03-01 00:00:00
abstract：:The prevalence of onychomycosis in the United States is estimated to be at least 12%; prevalence increases with increasing age and is highest in individuals more than 65 years of age. Trichophyton rubrum, which also causes tinea pedis, is responsible for approximately 90% of cases of toenail onychomycosis. Risk factor...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.0014
更新日期：2013-06-01 00:00:00
abstract：:Cutaneous infections are common in dermatology. They occur in all populations and all ages. This review will focus on 3 emerging infections encountered by dermatologists; community-acquired methicillin-resistant Staphylococcus aureus, Epstein-Barr virus infections, and the atypical mycobacterial infections. The backgr...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2006.08.003
更新日期：2006-12-01 00:00:00
abstract：:This article discusses the approach to the acute, generalized, blistering patient from the perspective of the dermatologic consultant. Initially, a case is presented, followed by a discussion of the relevant evaluation, differential diagnosis, and treatment options. ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2007.09.006
更新日期：2007-09-01 00:00:00
abstract：:Closing surgical defects of the external ear poses unique challenges because of the convoluted shape and thin tethered skin. Choice of repair is often dictated by the site of the wound. If the defect is central and anterior with intact cartilage, most defects will do well by second intention healing or grafting. If th...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/S1085-5629(03)00077-4
更新日期：2003-12-01 00:00:00
abstract：:Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in MCC has escalated. Recent effort has broadened our breadth of knowledge regardi...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2011.02.001
更新日期：2011-03-01 00:00:00
abstract：:Hidradenitis suppurativa (HS) is a complex dermatological disease characterized by recurrent painful nodules and suppuration in areas such as the axilla and groin. The disease is poorly understood and treatment is not satisfactory. In October 2016, the Canadian and United States Hidradenitis Suppurativa Foundations or...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2017.024
更新日期：2017-06-01 00:00:00
abstract：:Cutaneous fibrosis is an integral component of a variety of human disorders including keloids, hypertrophic scar, and most notably, scleroderma. Each has its own etiology and unique clinical characteristics, but all involve the dysregulation of connective tissue metabolism, in particular, the activation of dermal fibr...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(98)80055-2
更新日期：1998-03-01 00:00:00
