Abstract：
:Deep morphea encompasses a variety of clinical entities in which inflammation and sclerosis are found in the deep dermis, panniculus, fascia, or superficial muscle. Morphea profunda, eosinophilic fasciitis, and disabling pansclerotic morphea of children are included in this group, but overlapping of the extent and depth of cutaneous involvement in these various conditions precludes their distinction on the sole basis of clinical or even histologic examination. Furthermore, the limits between morphea profunda and generalized morphea, which usually are classified outside this group, are not clear. Histologically, all these disorders show similar inflammatory and sclerotic findings, the primary difference being the depth of these changes. Associated clinical findings, including arthralgias, arthritis, contractures, or carpal tunnel syndrome, are frequent. Although visceral complications are uncommon, pulmonary, esophageal, and even cardiac abnormalities have been reported. Eosinophilia, hypergammaglobulinemia, and increased erythrocyte sedimentation rate may be present with disease activity. Laboratory studies may demonstrate autoantibody production. Treatment is nonstandardized but UVA irradiation and antiinflammatory or immunosuppressive drugs (mainly antimalarial agents and corticosteroids) may be beneficial.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Bielsa I,Ariza Adoi
10.1016/j.sder.2007.02.005subject
Has Abstractpub_date
2007-06-01 00:00:00pages
90-5issue
2eissn
1085-5629issn
1558-0768pii
S1085-5629(07)00006-5journal_volume
26pub_type
杂志文章,评审abstract：:Teledermatology (TD) is a health care delivery modality that uses telecommunication technology to provide dermatologic care. It has grown to be a reliable and diagnostically accurate means of producing quality care while increasing access and reducing wait times in the outpatient setting. In the inpatient setting, TD ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2017.004
更新日期：2017-03-01 00:00:00
abstract：:Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in MCC has escalated. Recent effort has broadened our breadth of knowledge regardi...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2011.02.001
更新日期：2011-03-01 00:00:00
abstract：:Nonsurgical procedures have become very popular for the rejuvenation of the aging face. Trends now are for less invasive procedures as well as for more preventative intervention to slow the damage from ultraviolet light and environmental factors, as well as from intrinsic aging. The goal of these procedures is to elim...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2006.06.011
更新日期：2006-09-01 00:00:00
abstract：:The influences of information technology have touched almost all aspects of our lives, and health care delivery has been no exception. Law, policy, and regulation have driven the adoption of electronic medical records, particularly over the past decade, driving fundamental changes to the practice of medicine in genera...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2019.005
更新日期：2019-03-01 00:00:00
abstract：:In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional gro...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2007.12.004
更新日期：2008-03-01 00:00:00
abstract：:The use of video in the informed consent process has been well documented in the literature to improve patient satisfaction, understanding, comprehension, and to decrease anxiety. At the MD Anderson Mohs Surgery Unit, we use high-definition (HD) audiovisual (AV) modules to assist with the delivery of informed consent ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.1016/j.sder.2008.02.001
更新日期：2008-03-01 00:00:00
abstract：:The expansion of telemedicine nationwide has resulted in many states adopting specific telemedicine regulations to avoid the issue of requiring a full medical license to practice telemedicine. How these laws and regulations relate to the practice of telepathology and teledermatology has not been well delineated. It is...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.0037
更新日期：2013-12-01 00:00:00
abstract：:Cutaneous basal and squamous cell carcinomas are among the most frequent malignancies in the white population, with the annual incidence estimates ranging from 1 million to 3.5 million cases in the United States. These tumors can occur either sporadically or in the context of hereditary genodermatoses with cancer pred...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2012.08.005
更新日期：2012-12-01 00:00:00
abstract：:Dermatologic manifestations are among the most common signs of systemic lupus erythematosus (SLE). The Hopkins Lupus Cohort study is a prospective study in which patients with SLE are seen on a quarterly basis for measurement of disease activity, laboratory tests, and assessment of morbidity and quality of life. This ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.1016/s1085-5629(98)80017-5
更新日期：1998-09-01 00:00:00
abstract：:The term "epidermal nevus syndrome" (ENS) has been used to describe the association of epidermal hamartomas and extra-cutaneous abnormalities. Epidermal nevi follow the lines of Blaschko. The majority of the extra-cutaneous manifestations involve the brain, eye, and skeletal systems. Several subsets with characteristi...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2008.03.006
更新日期：2007-12-01 00:00:00
abstract：:Electronic billing systems make dermatology practices more efficient and productive. The decision to purchase and install such a system, however, involves a significant amount of time and is often accompanied by many mistakes. This article presents errors commonly made in the evaluation and purchase process and offers...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(00)80025-5
更新日期：2000-09-01 00:00:00
abstract：:Effective antimicrobials are critical in controlling one of the most common conditions encountered in medicine, namely, skin and skin structure infections. Unfortunately, the identification of appropriate and novel antimicrobials is continually challenged by the emergence of antimicrobial resistance among bacteria, fu...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2006.04.006
更新日期：2006-06-01 00:00:00
abstract：:The pathophysiology of atopic dermatitis (AD) is complex, and future treatment options will likely be incorporated in a multimodal approach to management. The new, directed therapies that have been developed will likely be used in conjunction with concomitant continuous or intermittent use of standard therapies; the g...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2016.044
更新日期：2016-06-01 00:00:00
abstract：:Idiosyncratic reactions (type B) are a major complication of drug therapy, because they are related to both the drug and to individual factors in the host. In comparison with other organs, the skin is quite frequently a target of allergic reactions, which are mainly elicited by small molecular weight compounds. This i...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(96)80035-6
更新日期：1996-12-01 00:00:00
abstract：:The intraepidermal vesiculobullous disorders constitute a wide variety of pathogenically unrelated disorders that share in common the formation of cleft or bullae formation within the epithelium. The etiologic, pathogenic, clinical and, in particular, the histopathologic attributes of the most important intraepidermal...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(03)00082-8
更新日期：2004-03-01 00:00:00
abstract：:The signs and symptoms of atopic dermatitis can be safely and effectively controlled in most patients; in many cases, the disease can be improved to the point that signs and symptoms are absent or minimal. In addition, flares can be effectively controlled and, in some cases, prevented. New topical medications, improve...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2017.011
更新日期：2017-03-01 00:00:00
abstract：:Superficial chemical peels and microdermabrasion are used for many dermatologic conditions. A common condition treated with these modalities is acne vulgaris. In this review, we discuss the theory behind the technique of these procedures and describe the application and complications of each of these procedures in the...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2008.06.003
更新日期：2008-09-01 00:00:00
abstract：:The techniques of noninvasive facial rejuvenation are forever being redefined and improved. This article will review historical as well as present approaches to resurfacing, discussing the nonablative tools that can complement resurfacing procedures. Current thoughts on the pre- and postoperative care of resurfacing p...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 历史文章,杂志文章
doi：
更新日期：2013-03-01 00:00:00
abstract：:The goal of treating the aging face is to restore facial balance and modify shadows. A facial evaluation should focus on areas of volume loss and opportunities to use neuromodulators (eg, botulinum toxin A) and the use of fillers. A thorough understanding of facial anatomy, including muscles, nerves, bone, and fat pad...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2016.038
更新日期：2016-06-01 00:00:00
abstract：:In 1996, oral terbinafine joined itraconazole and fluconazole on the short list of systemic medications that could be used to treat onychomycosis (although fluconazole was not approved for this indication by the US Food and Drug Administration [FDA], it was commonly used for this purpose). In 1999, ciclopirox was the ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2016.009
更新日期：2016-03-01 00:00:00
abstract：:Hair disorders include hair loss, increased hair growth, and hair structure defects with increased breakage, as well as unacceptable cosmetic appearance, such as reduced shine, strength, curliness, and elasticity. It is the task of the dermatologist to choose the right diagnostic tool depending on the suspected clinic...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2008.12.005
更新日期：2009-03-01 00:00:00
abstract：:Hidradenitis suppurativa (HS) is a complex dermatological disease characterized by recurrent painful nodules and suppuration in areas such as the axilla and groin. The disease is poorly understood and treatment is not satisfactory. In October 2016, the Canadian and United States Hidradenitis Suppurativa Foundations or...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.2017.024
更新日期：2017-06-01 00:00:00
abstract：:Atopic dermatitis (AD) is a chronic skin condition affecting children and adults, with a significant negative impact on patient and caregiver quality of life (QOL). Although effective treatments for AD are available, outcomes are often limited by poor adherence to treatment plans. Effective patient and caregiver educa...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2017.029
更新日期：2017-09-01 00:00:00
abstract：:The ascomycin macrolactam derivative pimecrolimus (Elidel, SDZ ASM 981; Novartis Pharma AG, Basel Switzerland) is a cell-selective inhibitor of inflammatory cytokines specifically developed for the treatment of inflammatory skin diseases, such as atopic dermatitis, allergic contact dermatitis, irritant contact dermati...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1053/sder.2001.29066
更新日期：2001-12-01 00:00:00
abstract：:Cellulite is a condition that affects the vast majority of women. Although it is of no danger to one's overall health, cellulite can be psychosocially debilitating. Consequently, much research has been devoted to understanding cellulite and its etiopathogenesis. With additional insights into the underlying causes of i...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2015.0169
更新日期：2015-09-01 00:00:00
abstract：:Cellulite is a common dermatologic condition and frequent cause of cosmetic concern among women. This paper aims to update what is known about the pathogenesis of cellulite and reviews targeted treatment modalities that address its underlying components of microvascular dysfunction, endocrine-mediated inflammation, an...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2018.056
更新日期：2018-12-01 00:00:00
abstract：:Although the majority of hemangiomas of infancy can be expected to follow a benign course, a significant subset may result in serious complications. Recently, hemangiomas of segmental morphology, or those which are large, plaque-like, and patterned in distribution, have been recognized as important markers for potenti...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2004.01.004
更新日期：2004-06-01 00:00:00
abstract：:Immunotherapy for the treatment of advanced melanoma has become a primary treatment in the clinic. Current therapies include systemic cytokines, immune checkpoint inhibitors, and localized intratumoral therapies. Checkpoint inhibitors block natural pathways that dampen or inhibit an immune response to stimulus. These ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.12788/j.sder.2018.028
更新日期：2018-06-01 00:00:00
abstract：:The history of resurfacing procedures used to treat the aging face is reviewed, and the place of laser resurfacing within this context is described. The changing medical reimbursement system and desire by "baby boomers" to maintain a youthful image have driven the technical development of laser resurfacing. Medical ma...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/s1085-5629(96)80052-6
更新日期：1996-09-01 00:00:00
abstract：:Safety remains paramount to the clinical utility of a therapy. Evaluation of safety is an ongoing process that does not end when a therapy becomes commercially available. This article reviews recent data pertaining to the safety profile of two therapeutic classes widely used in the treatment of psoriasis: inhibitors o...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
doi：10.12788/j.sder.0099
更新日期：2014-06-01 00:00:00
