Abstract:
:Effective antimicrobials are critical in controlling one of the most common conditions encountered in medicine, namely, skin and skin structure infections. Unfortunately, the identification of appropriate and novel antimicrobials is continually challenged by the emergence of antimicrobial resistance among bacteria, fungi, and parasites. This work will focus on describing novel antibacterials and antifungals approved by the United States Food and Drug Administration in the past 4 years.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Yang A,Kerdel FAdoi
10.1016/j.sder.2006.04.006subject
Has Abstractpub_date
2006-06-01 00:00:00pages
94-9issue
2eissn
1085-5629issn
1558-0768pii
S1085-5629(06)00034-4journal_volume
25pub_type
杂志文章,评审abstract::Lasers frequently are used by dermatologists for their multiple aesthetic applications, but they also can be used to treat a variety of medical dermatology conditions. Conditions such as acne vulgaris, psoriasis, and vitiligo can all be successfully treated with laser, thereby providing the patient with additional the...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1016/j.sder.2008.10.003
更新日期:2008-12-01 00:00:00
abstract::The last decade has witnessed a significant advance in the management of refractory moderate-to-severe psoriasis. This advance is the introduction of biological therapies to clinical practice. Three classes of biological therapies have been used. Of the first 2 classes to be introduced, the T-cell inhibitors and tumor...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2010.02.004
更新日期:2010-03-01 00:00:00
abstract::Thalidomide, originally marketed as a sedative, was introduced in West Germany in 1956 and in numerous other countries soon thereafter. In part because it did not impair coordination or respiratory function, the drug rapidly became extremely popular. By 1961, however, there were mounting reports of phocomelia and othe...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(98)80019-9
更新日期:1998-12-01 00:00:00
abstract::Atopic dermatitis (AD) is a chronic, pruritic, inflammatory skin condition that is associated with immune dysregulation and epidermal barrier dysfunction. The imbalance of the Th2 and Th1 pathways and their associated cytokines in AD presents as one facet of the pathogenic mechanisms. Changes in the T-cell populations...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.0018
更新日期:2013-09-01 00:00:00
abstract::Electronic billing systems make dermatology practices more efficient and productive. The decision to purchase and install such a system, however, involves a significant amount of time and is often accompanied by many mistakes. This article presents errors commonly made in the evaluation and purchase process and offers...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(00)80025-5
更新日期:2000-09-01 00:00:00
abstract::Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus. Topical and systemic agents as well as broadband ultraviolet photo...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2011.04.005
更新日期:2011-06-01 00:00:00
abstract::Congenital hemangiomas are rare solitary vascular tumors that do not proliferate after birth. They are characterized as either rapidly involuting congenital hemangiomas (RICHs) or noninvoluting congenital hemangiomas (NICHs) based on their clinical progression. NICHs have no associated complications, but are persisten...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2016.045
更新日期:2016-09-01 00:00:00
abstract::Bathing and moisturization to control dryness, applications of topical anti-inflammatory agents (including corticosteroids and calcineurin inhibitors [TCIs]) to control flares, minimization of the risk for infection, and relief of pruritus are the cornerstones of effective therapy for atopic dermatitis. Education of p...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2012.07.004
更新日期:2012-09-01 00:00:00
abstract::The ascomycin macrolactam derivative pimecrolimus (Elidel, SDZ ASM 981; Novartis Pharma AG, Basel Switzerland) is a cell-selective inhibitor of inflammatory cytokines specifically developed for the treatment of inflammatory skin diseases, such as atopic dermatitis, allergic contact dermatitis, irritant contact dermati...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1053/sder.2001.29066
更新日期:2001-12-01 00:00:00
abstract::One of the most interesting medical conditions that now afflicts the baby boomer generation is photoaging. Clinical signs of photoaging of the skin include rhytids, lentigines, keratoses, telangiectasia, loss of translucency, loss of elasticity, and sallow color. A systematic classification of patient photoaging types...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(96)80003-4
更新日期:1996-09-01 00:00:00
abstract::Superficial chemical peels and microdermabrasion are used for many dermatologic conditions. A common condition treated with these modalities is acne vulgaris. In this review, we discuss the theory behind the technique of these procedures and describe the application and complications of each of these procedures in the...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2008.06.003
更新日期:2008-09-01 00:00:00
abstract::This article discusses the approach to the acute, generalized, blistering patient from the perspective of the dermatologic consultant. Initially, a case is presented, followed by a discussion of the relevant evaluation, differential diagnosis, and treatment options. ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2007.09.006
更新日期:2007-09-01 00:00:00
abstract::The expansion of telemedicine nationwide has resulted in many states adopting specific telemedicine regulations to avoid the issue of requiring a full medical license to practice telemedicine. How these laws and regulations relate to the practice of telepathology and teledermatology has not been well delineated. It is...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.0037
更新日期:2013-12-01 00:00:00
abstract::Immunotherapy for the treatment of advanced melanoma has become a primary treatment in the clinic. Current therapies include systemic cytokines, immune checkpoint inhibitors, and localized intratumoral therapies. Checkpoint inhibitors block natural pathways that dampen or inhibit an immune response to stimulus. These ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2018.028
更新日期:2018-06-01 00:00:00
abstract::The pathophysiology of atopic dermatitis (AD) is complex, and future treatment options will likely be incorporated in a multimodal approach to management. The new, directed therapies that have been developed will likely be used in conjunction with concomitant continuous or intermittent use of standard therapies; the g...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2016.044
更新日期:2016-06-01 00:00:00
abstract::In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional gro...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2007.12.004
更新日期:2008-03-01 00:00:00
abstract::Safety remains paramount to the clinical utility of a therapy. Evaluation of safety is an ongoing process that does not end when a therapy becomes commercially available. This article reviews recent data pertaining to the safety profile of two therapeutic classes widely used in the treatment of psoriasis: inhibitors o...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.0099
更新日期:2014-06-01 00:00:00
abstract::Cutaneous infections are common in dermatology. They occur in all populations and all ages. This review will focus on 3 emerging infections encountered by dermatologists; community-acquired methicillin-resistant Staphylococcus aureus, Epstein-Barr virus infections, and the atypical mycobacterial infections. The backgr...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2006.08.003
更新日期:2006-12-01 00:00:00
abstract::Dermatologists will enter into a number of different contracts during their professional careers. It is important that in each agreement they enter, dermatologists reap the benefits that they aspire for and understand the consequences of each provision. This article addresses just a few of the different issues that ar...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2005.05.004
更新日期:2005-09-01 00:00:00
abstract::Lasers, both in single and multiple wavelength designs, have recently been introduced to enhance the results of liposuction. Safe parameters of fluence and temperature have not yet been described. In this study, I describe a series of laser lipolysis patients treated with a dual wavelength (1064/1319 nm) laser where i...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1016/j.sder.2009.11.002
更新日期:2009-12-01 00:00:00
abstract::Vitiligo involves a progressive loss of melanocytes from the epidermis and hair follicles. Milky-white patches appear resulting in cosmetic disfiguration that is most apparent in dark-skinned individuals. The disease is further classified according to distribution pattern and extent of depigmentation. The presence of ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(97)80030-2
更新日期:1997-03-01 00:00:00
abstract::The history of resurfacing procedures used to treat the aging face is reviewed, and the place of laser resurfacing within this context is described. The changing medical reimbursement system and desire by "baby boomers" to maintain a youthful image have driven the technical development of laser resurfacing. Medical ma...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(96)80052-6
更新日期:1996-09-01 00:00:00
abstract::Atopic dermatitis (AD) is a chronic skin condition affecting children and adults, with a significant negative impact on patient and caregiver quality of life (QOL). Although effective treatments for AD are available, outcomes are often limited by poor adherence to treatment plans. Effective patient and caregiver educa...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2017.029
更新日期:2017-09-01 00:00:00
abstract::The history of burn scars can best be found in military medical history. The care of wounded soldiers documented in the Illiad reflected the trauma of the weapons of war, arrow, spear, sword, and ax. The introduction of gunpowder in the 14th century, increasingly sophisticated explosives, and in modern times, petroleu...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2015.0140
更新日期:2015-03-01 00:00:00
abstract::The term "epidermal nevus syndrome" (ENS) has been used to describe the association of epidermal hamartomas and extra-cutaneous abnormalities. Epidermal nevi follow the lines of Blaschko. The majority of the extra-cutaneous manifestations involve the brain, eye, and skeletal systems. Several subsets with characteristi...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2008.03.006
更新日期:2007-12-01 00:00:00
abstract::Phototherapeutic modalities, including narrowband-UVB, broadband-UVB, PUVA photochemotherapy, and excimer laser therapy are valuable tools that can be used for photoresponsive dermatoses in children. As a systematically safer alternative compared with internal agents, including the prebiologic and biological therapies...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2010.03.006
更新日期:2010-06-01 00:00:00
abstract::Hidradenitis suppurativa (HS) is a complex dermatological disease characterized by recurrent painful nodules and suppuration in areas such as the axilla and groin. The disease is poorly understood and treatment is not satisfactory. In October 2016, the Canadian and United States Hidradenitis Suppurativa Foundations or...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2017.024
更新日期:2017-06-01 00:00:00
abstract::Artecoll was developed about 20 years ago and underwent a number of production changes until it recently became FDA approved under the new name of Artefill. This product contains 20% polymethyl methacrylate (PMMA) microspheres with a diameter of 30 to 40 microm, which are suspended in a 3.5% atelo-collagen solution. T...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2004.08.002
更新日期:2004-12-01 00:00:00
abstract::The development of fractional photothermolysis is a milestone in the history of laser technology and cutaneous resurfacing. Based on the concept that skin is treated in a fractional manner, where narrow cylinders of tissue are thermally heated and normal adjacent skin is left unaffected, the fractional devices have sh...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2012.02.003
更新日期:2012-06-01 00:00:00
abstract::Cutaneous basal and squamous cell carcinomas are among the most frequent malignancies in the white population, with the annual incidence estimates ranging from 1 million to 3.5 million cases in the United States. These tumors can occur either sporadically or in the context of hereditary genodermatoses with cancer pred...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2012.08.005
更新日期:2012-12-01 00:00:00