Immunotherapy for melanoma.

abstract：:Deep morphea encompasses a variety of clinical entities in which inflammation and sclerosis are found in the deep dermis, panniculus, fascia, or superficial muscle. Morphea profunda, eosinophilic fasciitis, and disabling pansclerotic morphea of children are included in this group, but overlapping of the extent and dep...

journal_title：Seminars in cutaneous medicine and surgery

authors： Bielsa I,Ariza A

更新日期：2007-06-01 00:00:00

abstract：:The prevalence of onychomycosis in the United States is estimated to be at least 12%; prevalence increases with increasing age and is highest in individuals more than 65 years of age. Trichophyton rubrum, which also causes tinea pedis, is responsible for approximately 90% of cases of toenail onychomycosis. Risk factor...

journal_title：Seminars in cutaneous medicine and surgery

authors： Scher RK,Rich P,Pariser D,Elewski B

更新日期：2013-06-01 00:00:00

abstract：:Medical imaging has dramatically transformed the practice of medicine, especially the field of dermatology. Imaging is used to facilitate the transfer of information between providers, document cutaneous disease, assess response to therapy, and plays a crucial role in monitoring and diagnosing skin cancer. Advancement...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hibler BP,Qi Q,Rossi AM

更新日期：2016-03-01 00:00:00

abstract：:The signs and symptoms of atopic dermatitis can be safely and effectively controlled in most patients; in many cases, the disease can be improved to the point that signs and symptoms are absent or minimal. In addition, flares can be effectively controlled and, in some cases, prevented. New topical medications, improve...

journal_title：Seminars in cutaneous medicine and surgery

authors： Stein Gold LF,Eichenfield LF

更新日期：2017-03-01 00:00:00

abstract：:Spitz nevus (SN) and Spitzoid malignant melanoma (SMM) represent benign and malignant counterparts at both ends of the spectrum of Spitzoid lesions. Atypical Spitzoid neoplasm (ASN) is a poorly defined and characterized category of melanocytic tumors with histologic features of both benign Spitz nevi and malignant mel...

journal_title：Seminars in cutaneous medicine and surgery

authors： Miteva M,Lazova R

更新日期：2010-09-01 00:00:00

abstract：:This review highlights melanoma trends observed among African-, Asian-, Latino- and Native-American populations. Melanoma is the most lethal form of skin cancer, accounting for about 75% of all skin cancer deaths. Generally, incidence rates increase with age, peak after age 40, and are greater in men than women. Howev...

journal_title：Seminars in cutaneous medicine and surgery

authors： Shoo BA,Kashani-Sabet M

更新日期：2009-06-01 00:00:00

abstract：:The development of fractional photothermolysis is a milestone in the history of laser technology and cutaneous resurfacing. Based on the concept that skin is treated in a fractional manner, where narrow cylinders of tissue are thermally heated and normal adjacent skin is left unaffected, the fractional devices have sh...

journal_title：Seminars in cutaneous medicine and surgery

authors： Saedi N,Jalian HR,Petelin A,Zachary C

更新日期：2012-06-01 00:00:00

abstract：:This article discusses the approach to the acute, generalized, blistering patient from the perspective of the dermatologic consultant. Initially, a case is presented, followed by a discussion of the relevant evaluation, differential diagnosis, and treatment options. ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Carr DR,Houshmand E,Heffernan MP

更新日期：2007-09-01 00:00:00

abstract：:Hidradenitis suppurativa (HS) is a complex dermatological disease characterized by recurrent painful nodules and suppuration in areas such as the axilla and groin. The disease is poorly understood and treatment is not satisfactory. In October 2016, the Canadian and United States Hidradenitis Suppurativa Foundations or...

journal_title：Seminars in cutaneous medicine and surgery

authors： Hoffman LK,Ghias MH,Garg A,Hamzavi IH,Alavi A,Lowes MA

更新日期：2017-06-01 00:00:00

abstract：:The expansion of telemedicine nationwide has resulted in many states adopting specific telemedicine regulations to avoid the issue of requiring a full medical license to practice telemedicine. How these laws and regulations relate to the practice of telepathology and teledermatology has not been well delineated. It is...

journal_title：Seminars in cutaneous medicine and surgery

authors： Marsch A,High WA

更新日期：2013-12-01 00:00:00

abstract：:"Venous disease consists of a spectrum with significant medical and economic morbidities. For lack of exposure, however, it is a poorly understood subject. The evaluation and approach to diagnosing venous disease requires a firm understanding of venous anatomy and pathophysiology. With a targeted history and physical,...

journal_title：Seminars in cutaneous medicine and surgery

authors： Nguyen TH

更新日期：2005-12-01 00:00:00

abstract：:Teledermatology (TD) is a health care delivery modality that uses telecommunication technology to provide dermatologic care. It has grown to be a reliable and diagnostically accurate means of producing quality care while increasing access and reducing wait times in the outpatient setting. In the inpatient setting, TD ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Tull R,Wanat KA

更新日期：2017-03-01 00:00:00

abstract：:Closing surgical defects of the external ear poses unique challenges because of the convoluted shape and thin tethered skin. Choice of repair is often dictated by the site of the wound. If the defect is central and anterior with intact cartilage, most defects will do well by second intention healing or grafting. If th...

journal_title：Seminars in cutaneous medicine and surgery

authors： Olbricht S,Liégeois NJ

更新日期：2003-12-01 00:00:00

abstract：:Lasers frequently are used by dermatologists for their multiple aesthetic applications, but they also can be used to treat a variety of medical dermatology conditions. Conditions such as acne vulgaris, psoriasis, and vitiligo can all be successfully treated with laser, thereby providing the patient with additional the...

journal_title：Seminars in cutaneous medicine and surgery

authors： Railan D,Alster TS

更新日期：2008-12-01 00:00:00

abstract：:There are certain disorders of hyper- and hypopigmentation that are more common in children with skin of color. It is imperative that practitioners can swiftly and accurately diagnose these pigmentary disorders to prevent delay in treatment and enhance quality of life. Pigmentary disorders have many etiologies and may...

journal_title：Seminars in cutaneous medicine and surgery

authors： Ascha M,Irfan M

更新日期：2016-12-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a rare, aggressive, and often fatal cutaneous malignancy that is not usually suspected at the time of biopsy. Because of its increasing incidence and the discovery of a possible viral association, interest in MCC has escalated. Recent effort has broadened our breadth of knowledge regardi...

journal_title：Seminars in cutaneous medicine and surgery

authors： Wang TS,Byrne PJ,Jacobs LK,Taube JM

更新日期：2011-03-01 00:00:00

abstract：:The intraepidermal vesiculobullous disorders constitute a wide variety of pathogenically unrelated disorders that share in common the formation of cleft or bullae formation within the epithelium. The etiologic, pathogenic, clinical and, in particular, the histopathologic attributes of the most important intraepidermal...

journal_title：Seminars in cutaneous medicine and surgery

authors： Cassandra M,Morgan M

更新日期：2004-03-01 00:00:00

abstract：:Prognosis and survival for patients diagnosed with melanoma depends on a number of interrelated factors, including histological, clinical, immunologic, and surgical parameters. Tumor thickness and depth of invasion is the most important prognostic factor, and helps to guide treatment and management plans. Besides tumo...

journal_title：Seminars in cutaneous medicine and surgery

authors： Brown M

更新日期：1997-06-01 00:00:00

abstract：:In 1996, oral terbinafine joined itraconazole and fluconazole on the short list of systemic medications that could be used to treat onychomycosis (although fluconazole was not approved for this indication by the US Food and Drug Administration [FDA], it was commonly used for this purpose). In 1999, ciclopirox was the ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Rosen T,Stein Gold LF

更新日期：2016-03-01 00:00:00

abstract：:Cutaneous B-cell lymphomas (CBCLs) are a heterogeneous group of diseases that can have variable presentations, prognoses, and treatments. The proper identification of a CBCL hinges on proper histopathologic and clinical evaluation. Comprising 25% to 30% of the primary cutaneous lymphomas, incident cases of CBCL are ra...

journal_title：Seminars in cutaneous medicine and surgery

authors： Chen ST,Barnes J,Duncan L

更新日期：2018-03-01 00:00:00

abstract：:Bathing and moisturization to control dryness, applications of topical anti-inflammatory agents (including corticosteroids and calcineurin inhibitors [TCIs]) to control flares, minimization of the risk for infection, and relief of pruritus are the cornerstones of effective therapy for atopic dermatitis. Education of p...

journal_title：Seminars in cutaneous medicine and surgery

authors： Paller AS,Simpson EL,Eichenfield LF,Ellis CN,Mancini AJ

更新日期：2012-09-01 00:00:00

abstract：:Cutaneous infections are common in dermatology. They occur in all populations and all ages. This review will focus on 3 emerging infections encountered by dermatologists; community-acquired methicillin-resistant Staphylococcus aureus, Epstein-Barr virus infections, and the atypical mycobacterial infections. The backgr...

journal_title：Seminars in cutaneous medicine and surgery

authors： Jackson JM

更新日期：2006-12-01 00:00:00

abstract：:Stromal relationships are crucial to metastatic spread of solid malignancies. Some aspects of this stroma interaction are obviously associated with particular morphological features, which may carry prognostic significance. In cutaneous melanoma, level of invasion, arrangement of cells (horizontal or vertical growth p...

journal_title：Seminars in cutaneous medicine and surgery

authors： Smolle J,Hofmann-Wellenhof R,Fink-Puches R

更新日期：1996-12-01 00:00:00

abstract：:Cutaneous fibrosis is an integral component of a variety of human disorders including keloids, hypertrophic scar, and most notably, scleroderma. Each has its own etiology and unique clinical characteristics, but all involve the dysregulation of connective tissue metabolism, in particular, the activation of dermal fibr...

journal_title：Seminars in cutaneous medicine and surgery

authors： Liu B,Connolly MK

更新日期：1998-03-01 00:00:00

abstract：:Melanoma is a particularly aggressive type of skin cancer, and its incidence has been increasing steadily since the 1970s. This article will review the extensive epidemiologic data demonstrating that ultraviolet radiation (UVR) exposure, from the sun or artificial tanning beds, is the most important environmental risk...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kanavy HE,Gerstenblith MR

更新日期：2011-12-01 00:00:00

abstract：:Idiosyncratic reactions (type B) are a major complication of drug therapy, because they are related to both the drug and to individual factors in the host. In comparison with other organs, the skin is quite frequently a target of allergic reactions, which are mainly elicited by small molecular weight compounds. This i...

journal_title：Seminars in cutaneous medicine and surgery

authors： Merk HF,Hertl M

更新日期：1996-12-01 00:00:00

abstract：:Several nonsurgical strategies for managing hidradenitis suppurativa (HS) are used that are successful in many patients. The overall goals of pharmacologic therapy are to clear or reduce the number and extent of current lesions and to prevent new lesions from forming. No pharmacologic agent is universally effective in...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kerdel FA

更新日期：2014-06-01 00:00:00

abstract：:The ascomycin macrolactam derivative pimecrolimus (Elidel, SDZ ASM 981; Novartis Pharma AG, Basel Switzerland) is a cell-selective inhibitor of inflammatory cytokines specifically developed for the treatment of inflammatory skin diseases, such as atopic dermatitis, allergic contact dermatitis, irritant contact dermati...

journal_title：Seminars in cutaneous medicine and surgery

authors： Stuetz A,Grassberger M,Meingassner JG

更新日期：2001-12-01 00:00:00

abstract：:In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional gro...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kunz M

更新日期：2008-03-01 00:00:00

abstract：:Thalidomide, originally marketed as a sedative, was introduced in West Germany in 1956 and in numerous other countries soon thereafter. In part because it did not impair coordination or respiratory function, the drug rapidly became extremely popular. By 1961, however, there were mounting reports of phocomelia and othe...

journal_title：Seminars in cutaneous medicine and surgery

authors： Stirling DI

更新日期：1998-12-01 00:00:00