Abstract:
:Dermatologic manifestations are among the most common signs of systemic lupus erythematosus (SLE). The Hopkins Lupus Cohort study is a prospective study in which patients with SLE are seen on a quarterly basis for measurement of disease activity, laboratory tests, and assessment of morbidity and quality of life. This cohort has allowed unique insights into the epidemiologic factors of SLE, the presentation of dermatologic lupus, and morbidity, all of which are presented in this report. In addition, the dermatologic signs of antiphospholipid antibody syndrome (APS) are reviewed. Approaches to treatment of dermatologic lupus and APS are discussed.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Petri Mdoi
10.1016/s1085-5629(98)80017-5subject
Has Abstractpub_date
1998-09-01 00:00:00pages
219-27issue
3eissn
1085-5629issn
1558-0768pii
S1085-5629(98)80017-5journal_volume
17pub_type
杂志文章abstract::Soft tissue augmentation has become increasingly important as more individuals seek aesthetic improvement without major surgical procedures. The choice of an appropriate subcutaneous implant, whether solid or injectable, requires a thorough understanding of the materials available. This review of the literature addres...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(99)80036-4
更新日期:1999-06-01 00:00:00
abstract::The pathophysiology of atopic dermatitis (AD) is complex, and future treatment options will likely be incorporated in a multimodal approach to management. The new, directed therapies that have been developed will likely be used in conjunction with concomitant continuous or intermittent use of standard therapies; the g...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2016.044
更新日期:2016-06-01 00:00:00
abstract::Idiosyncratic reactions (type B) are a major complication of drug therapy, because they are related to both the drug and to individual factors in the host. In comparison with other organs, the skin is quite frequently a target of allergic reactions, which are mainly elicited by small molecular weight compounds. This i...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(96)80035-6
更新日期:1996-12-01 00:00:00
abstract::Oral mucosal bullous/desquamative/ulcerative diseases involve immunopathological mechanisms that account for loss of adhesion between contiguous keratinocytes or to structures within the basal lamina. Some are antibody mediated, in which specific adhesion molecules of the desmosome, hemidesmosome, and basement membran...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(97)80018-1
更新日期:1997-12-01 00:00:00
abstract::In an attempt to limit the prolonged postoperative healing associated with ablative laser skin resurfacing and in response to growing public interest in less invasive treatment modalities, nonablative laser and light source technology was developed. Over the past few years, several clinical and histologic research stu...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1053/sder.2002.36766
更新日期:2002-12-01 00:00:00
abstract::In dermatology, botulinum toxin is now most often used to reduce dynamic facial creases and treat primary focal hyperhidrosis. The exemplary safety record of this medication is such that after nearly 2 decades, it is not known to have any long-term adverse events. Transient adverse events, such as mild injection pain,...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1016/j.sder.2006.12.004
更新日期:2007-03-01 00:00:00
abstract::In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional gro...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2007.12.004
更新日期:2008-03-01 00:00:00
abstract::One of the most interesting medical conditions that now afflicts the baby boomer generation is photoaging. Clinical signs of photoaging of the skin include rhytids, lentigines, keratoses, telangiectasia, loss of translucency, loss of elasticity, and sallow color. A systematic classification of patient photoaging types...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(96)80003-4
更新日期:1996-09-01 00:00:00
abstract::The prevalence of onychomycosis in the United States is estimated to be at least 12%; prevalence increases with increasing age and is highest in individuals more than 65 years of age. Trichophyton rubrum, which also causes tinea pedis, is responsible for approximately 90% of cases of toenail onychomycosis. Risk factor...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.0014
更新日期:2013-06-01 00:00:00
abstract::The development of fractional photothermolysis has revolutionized the treatment of skin scarring, rejuvenation, and tightening. By creating targeted microthermal zones and leaving surrounding tissue intact, this concept has provided the field with efficacious results, with less downtime and a better safety profile. Th...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2017.039
更新日期:2017-12-01 00:00:00
abstract::The last decade has witnessed a significant advance in the management of refractory moderate-to-severe psoriasis. This advance is the introduction of biological therapies to clinical practice. Three classes of biological therapies have been used. Of the first 2 classes to be introduced, the T-cell inhibitors and tumor...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2010.02.004
更新日期:2010-03-01 00:00:00
abstract::This article discusses the approach to the acute, generalized, blistering patient from the perspective of the dermatologic consultant. Initially, a case is presented, followed by a discussion of the relevant evaluation, differential diagnosis, and treatment options. ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2007.09.006
更新日期:2007-09-01 00:00:00
abstract::Nonsurgical procedures have become very popular for the rejuvenation of the aging face. Trends now are for less invasive procedures as well as for more preventative intervention to slow the damage from ultraviolet light and environmental factors, as well as from intrinsic aging. The goal of these procedures is to elim...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2006.06.011
更新日期:2006-09-01 00:00:00
abstract::There are certain disorders of hyper- and hypopigmentation that are more common in children with skin of color. It is imperative that practitioners can swiftly and accurately diagnose these pigmentary disorders to prevent delay in treatment and enhance quality of life. Pigmentary disorders have many etiologies and may...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2016.064
更新日期:2016-12-01 00:00:00
abstract::Cellulite is a condition that affects the vast majority of women. Although it is of no danger to one's overall health, cellulite can be psychosocially debilitating. Consequently, much research has been devoted to understanding cellulite and its etiopathogenesis. With additional insights into the underlying causes of i...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2015.0169
更新日期:2015-09-01 00:00:00
abstract::Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus. Topical and systemic agents as well as broadband ultraviolet photo...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2011.04.005
更新日期:2011-06-01 00:00:00
abstract::Superficial chemical peels and microdermabrasion are used for many dermatologic conditions. A common condition treated with these modalities is acne vulgaris. In this review, we discuss the theory behind the technique of these procedures and describe the application and complications of each of these procedures in the...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2008.06.003
更新日期:2008-09-01 00:00:00
abstract::Nonpharmacologic management of psychodermatologic conditions includes both structured and unstructured interventions that may ameliorate skin disorders, reduce psychological distress, and improve the functional status of the affected individual. Nonpharmacologic techniques are often referred to as psychocutaneous inte...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.0011
更新日期:2013-06-01 00:00:00
abstract::"Venous disease consists of a spectrum with significant medical and economic morbidities. For lack of exposure, however, it is a poorly understood subject. The evaluation and approach to diagnosing venous disease requires a firm understanding of venous anatomy and pathophysiology. With a targeted history and physical,...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2005.10.001
更新日期:2005-12-01 00:00:00
abstract::Atopic dermatitis (AD) is a chronic skin condition affecting children and adults, with a significant negative impact on patient and caregiver quality of life (QOL). Although effective treatments for AD are available, outcomes are often limited by poor adherence to treatment plans. Effective patient and caregiver educa...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2017.029
更新日期:2017-09-01 00:00:00
abstract::Lasers, both in single and multiple wavelength designs, have recently been introduced to enhance the results of liposuction. Safe parameters of fluence and temperature have not yet been described. In this study, I describe a series of laser lipolysis patients treated with a dual wavelength (1064/1319 nm) laser where i...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1016/j.sder.2009.11.002
更新日期:2009-12-01 00:00:00
abstract::Artecoll was developed about 20 years ago and underwent a number of production changes until it recently became FDA approved under the new name of Artefill. This product contains 20% polymethyl methacrylate (PMMA) microspheres with a diameter of 30 to 40 microm, which are suspended in a 3.5% atelo-collagen solution. T...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2004.08.002
更新日期:2004-12-01 00:00:00
abstract::Hair shaft abnormalities are fascinating and can provide a diagnostic challenge. Current knowledge of structural changes in hair has been amplified by scanning and transmission electron microscopy (SEM and TEM). Dermatologists using the light microscope and polarization in the office can diagnose the great majority of...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2006.01.004
更新日期:2006-03-01 00:00:00
abstract::Cutaneous infections are common in dermatology. They occur in all populations and all ages. This review will focus on 3 emerging infections encountered by dermatologists; community-acquired methicillin-resistant Staphylococcus aureus, Epstein-Barr virus infections, and the atypical mycobacterial infections. The backgr...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2006.08.003
更新日期:2006-12-01 00:00:00
abstract::The term "epidermal nevus syndrome" (ENS) has been used to describe the association of epidermal hamartomas and extra-cutaneous abnormalities. Epidermal nevi follow the lines of Blaschko. The majority of the extra-cutaneous manifestations involve the brain, eye, and skeletal systems. Several subsets with characteristi...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2008.03.006
更新日期:2007-12-01 00:00:00
abstract::Electronic billing systems make dermatology practices more efficient and productive. The decision to purchase and install such a system, however, involves a significant amount of time and is often accompanied by many mistakes. This article presents errors commonly made in the evaluation and purchase process and offers...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(00)80025-5
更新日期:2000-09-01 00:00:00
abstract::Thalidomide, originally marketed as a sedative, was introduced in West Germany in 1956 and in numerous other countries soon thereafter. In part because it did not impair coordination or respiratory function, the drug rapidly became extremely popular. By 1961, however, there were mounting reports of phocomelia and othe...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(98)80019-9
更新日期:1998-12-01 00:00:00
abstract::The techniques of noninvasive facial rejuvenation are forever being redefined and improved. This article will review historical as well as present approaches to resurfacing, discussing the nonablative tools that can complement resurfacing procedures. Current thoughts on the pre- and postoperative care of resurfacing p...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 历史文章,杂志文章
doi:
更新日期:2013-03-01 00:00:00
abstract::Skin cancers are the most common form of malignancy. Early diagnosis and treatment provides the best chance for survival and reduced morbidity. However, some patients have recurrent or resistant lesions. In patients with basal cell carcinoma (BCC), prognosis is relatively good for all four types of lesions (superficia...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2011.11.003
更新日期:2011-12-01 00:00:00
abstract::Prognosis and survival for patients diagnosed with melanoma depends on a number of interrelated factors, including histological, clinical, immunologic, and surgical parameters. Tumor thickness and depth of invasion is the most important prognostic factor, and helps to guide treatment and management plans. Besides tumo...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(97)80005-3
更新日期:1997-06-01 00:00:00