Abstract:
:Prognosis and survival for patients diagnosed with melanoma depends on a number of interrelated factors, including histological, clinical, immunologic, and surgical parameters. Tumor thickness and depth of invasion is the most important prognostic factor, and helps to guide treatment and management plans. Besides tumor thickness, other histological criteria include melanoma growth phase (nodal v. vertical), host response, angiolymphatic invasion, mitotic rate, regression, satellitosis, and neurotropism. Important clinical prognostic factors include anatomic location of the melanoma and the patient's age and sex. Surgical factors to be examined involve excisional margin size, and elective lymph node dissection. Finally, the staging of patients with melanomas (nodal or visceral metastases) helps to define survival.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Brown Mdoi
10.1016/s1085-5629(97)80005-3subject
Has Abstractpub_date
1997-06-01 00:00:00pages
113-21issue
2eissn
1085-5629issn
1558-0768pii
S1085-5629(97)80005-3journal_volume
16pub_type
杂志文章,评审abstract::Hidradenitis suppurativa (HS) is a complex dermatological disease characterized by recurrent painful nodules and suppuration in areas such as the axilla and groin. The disease is poorly understood and treatment is not satisfactory. In October 2016, the Canadian and United States Hidradenitis Suppurativa Foundations or...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2017.024
更新日期:2017-06-01 00:00:00
abstract::The pathophysiology of atopic dermatitis (AD) is complex, and future treatment options will likely be incorporated in a multimodal approach to management. The new, directed therapies that have been developed will likely be used in conjunction with concomitant continuous or intermittent use of standard therapies; the g...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2016.044
更新日期:2016-06-01 00:00:00
abstract::In dermatology, botulinum toxin is now most often used to reduce dynamic facial creases and treat primary focal hyperhidrosis. The exemplary safety record of this medication is such that after nearly 2 decades, it is not known to have any long-term adverse events. Transient adverse events, such as mild injection pain,...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1016/j.sder.2006.12.004
更新日期:2007-03-01 00:00:00
abstract::Stromal relationships are crucial to metastatic spread of solid malignancies. Some aspects of this stroma interaction are obviously associated with particular morphological features, which may carry prognostic significance. In cutaneous melanoma, level of invasion, arrangement of cells (horizontal or vertical growth p...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(96)80046-0
更新日期:1996-12-01 00:00:00
abstract::Mycosis fungoides is a peripheral non-Hodgkin's T-cell neoplastic process, representing the most common type of primary cutaneous malignant lymphoma. Neoplastic lesions classically show skin predilection and characteristic clinical and histologic features in patch, plaque, and tumor stages. In addition, several clinic...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(00)80005-x
更新日期:2000-06-01 00:00:00
abstract::The development of fractional photothermolysis has revolutionized the treatment of skin scarring, rejuvenation, and tightening. By creating targeted microthermal zones and leaving surrounding tissue intact, this concept has provided the field with efficacious results, with less downtime and a better safety profile. Th...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2017.039
更新日期:2017-12-01 00:00:00
abstract::There are certain disorders of hyper- and hypopigmentation that are more common in children with skin of color. It is imperative that practitioners can swiftly and accurately diagnose these pigmentary disorders to prevent delay in treatment and enhance quality of life. Pigmentary disorders have many etiologies and may...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2016.064
更新日期:2016-12-01 00:00:00
abstract::Effective antimicrobials are critical in controlling one of the most common conditions encountered in medicine, namely, skin and skin structure infections. Unfortunately, the identification of appropriate and novel antimicrobials is continually challenged by the emergence of antimicrobial resistance among bacteria, fu...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2006.04.006
更新日期:2006-06-01 00:00:00
abstract::Medical imaging has dramatically transformed the practice of medicine, especially the field of dermatology. Imaging is used to facilitate the transfer of information between providers, document cutaneous disease, assess response to therapy, and plays a crucial role in monitoring and diagnosing skin cancer. Advancement...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2016.001
更新日期:2016-03-01 00:00:00
abstract::This review highlights melanoma trends observed among African-, Asian-, Latino- and Native-American populations. Melanoma is the most lethal form of skin cancer, accounting for about 75% of all skin cancer deaths. Generally, incidence rates increase with age, peak after age 40, and are greater in men than women. Howev...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2009.04.005
更新日期:2009-06-01 00:00:00
abstract::This is a very exciting time in cutaneous laser surgery with an ever-expanding therapeutic armamentarium and an increased sophistication of available technology. These recent trends have allowed for both a rapid development of interest and exploration of laser-assisted drug delivery and its potential applications. We ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.0119
更新日期:2014-12-01 00:00:00
abstract::Psoriasis is now recognized as an immunologically mediated systemic disease that may be expressed in cutaneous and joint symptoms. Medications that were once thought to control psoriasis by reducing keratinocyte proliferation are now known to act on immunologic pathways. In recent years, the emerging understanding of ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.0067
更新日期:2014-03-01 00:00:00
abstract::The expansion of telemedicine nationwide has resulted in many states adopting specific telemedicine regulations to avoid the issue of requiring a full medical license to practice telemedicine. How these laws and regulations relate to the practice of telepathology and teledermatology has not been well delineated. It is...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.0037
更新日期:2013-12-01 00:00:00
abstract::Infections with organisms of the genus Bartonella, for many years important only in South and Central America, have assumed significance in developing countries, especially in conjunction with the advent of the pandemic of the human immunodeficiency virus infection. New molecular and culture techniques have determined...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(97)80042-9
更新日期:1997-09-01 00:00:00
abstract::The ascomycin macrolactam derivative pimecrolimus (Elidel, SDZ ASM 981; Novartis Pharma AG, Basel Switzerland) is a cell-selective inhibitor of inflammatory cytokines specifically developed for the treatment of inflammatory skin diseases, such as atopic dermatitis, allergic contact dermatitis, irritant contact dermati...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1053/sder.2001.29066
更新日期:2001-12-01 00:00:00
abstract::The intraepidermal vesiculobullous disorders constitute a wide variety of pathogenically unrelated disorders that share in common the formation of cleft or bullae formation within the epithelium. The etiologic, pathogenic, clinical and, in particular, the histopathologic attributes of the most important intraepidermal...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(03)00082-8
更新日期:2004-03-01 00:00:00
abstract::The use of video in the informed consent process has been well documented in the literature to improve patient satisfaction, understanding, comprehension, and to decrease anxiety. At the MD Anderson Mohs Surgery Unit, we use high-definition (HD) audiovisual (AV) modules to assist with the delivery of informed consent ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.1016/j.sder.2008.02.001
更新日期:2008-03-01 00:00:00
abstract::One of the most interesting medical conditions that now afflicts the baby boomer generation is photoaging. Clinical signs of photoaging of the skin include rhytids, lentigines, keratoses, telangiectasia, loss of translucency, loss of elasticity, and sallow color. A systematic classification of patient photoaging types...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(96)80003-4
更新日期:1996-09-01 00:00:00
abstract::Among the newer medications for treating psoriasis are the interleukin-17A inhibitor secukinumab and the phosphodiesterase 4 inhibitor apremilast. Secukinumab offers a level of efficacy greater than that of the tumor necrosis factor-α inhibitor adalimumab. Apremilast is associated with lower levels of efficacy than th...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.2016.020
更新日期:2016-06-01 00:00:00
abstract::Superficial chemical peels and microdermabrasion are used for many dermatologic conditions. A common condition treated with these modalities is acne vulgaris. In this review, we discuss the theory behind the technique of these procedures and describe the application and complications of each of these procedures in the...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/j.sder.2008.06.003
更新日期:2008-09-01 00:00:00
abstract::The history of resurfacing procedures used to treat the aging face is reviewed, and the place of laser resurfacing within this context is described. The changing medical reimbursement system and desire by "baby boomers" to maintain a youthful image have driven the technical development of laser resurfacing. Medical ma...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(96)80052-6
更新日期:1996-09-01 00:00:00
abstract::Several nonsurgical strategies for managing hidradenitis suppurativa (HS) are used that are successful in many patients. The overall goals of pharmacologic therapy are to clear or reduce the number and extent of current lesions and to prevent new lesions from forming. No pharmacologic agent is universally effective in...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.0094
更新日期:2014-06-01 00:00:00
abstract::Studies of the prevalence of atopic dermatitis (AD) have provided insights into associated environmental risk factors, demonstrating the complex interactions between the presence of filaggrin (FLG) gene defects and environment. Among other important findings is that elevated transepidermal water loss (TEWL) in newborn...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2016.041
更新日期:2016-06-01 00:00:00
abstract::The influences of information technology have touched almost all aspects of our lives, and health care delivery has been no exception. Law, policy, and regulation have driven the adoption of electronic medical records, particularly over the past decade, driving fundamental changes to the practice of medicine in genera...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2019.005
更新日期:2019-03-01 00:00:00
abstract::There has been a dramatic increase in the incidence of malignant melanoma in most parts of the world. Because the tumor thickness is the most important prognostic factor for the prognosis of the malignant melanoma, the early detection of thin melanomas is essential. Dermatoscopy allows the physician to discriminate be...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1053/sder.2003.50001
更新日期:2003-03-01 00:00:00
abstract::Cutaneous B-cell lymphomas (CBCLs) are a heterogeneous group of diseases that can have variable presentations, prognoses, and treatments. The proper identification of a CBCL hinges on proper histopathologic and clinical evaluation. Comprising 25% to 30% of the primary cutaneous lymphomas, incident cases of CBCL are ra...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2018.014
更新日期:2018-03-01 00:00:00
abstract::Perioral dermatitis is a unique skin disorder of childhood. Its exact origin is unknown; it is probably an idiosyncratic response to exogenous factors such as the use of a topical fluorinated corticosteroid or other substances on the face. It is uncommon but not rare. The age of affected children has ranged from 7 mon...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(99)80018-2
更新日期:1999-09-01 00:00:00
abstract::The term bed bug is applied to 2 species of genus Cimex: lectularius describes the common or temperate bed bug, and hemipterus its tropical cousin. Cimex lectularius is aptly named; its genus and species derive from the Latin words for bug and bed, respectively. Though the tiny pest is receiving increased public atten...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章
doi:10.12788/j.sder.0106
更新日期:2014-09-01 00:00:00
abstract::Immunotherapy for the treatment of advanced melanoma has become a primary treatment in the clinic. Current therapies include systemic cytokines, immune checkpoint inhibitors, and localized intratumoral therapies. Checkpoint inhibitors block natural pathways that dampen or inhibit an immune response to stimulus. These ...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.12788/j.sder.2018.028
更新日期:2018-06-01 00:00:00
abstract::Electronic billing systems make dermatology practices more efficient and productive. The decision to purchase and install such a system, however, involves a significant amount of time and is often accompanied by many mistakes. This article presents errors commonly made in the evaluation and purchase process and offers...
journal_title:Seminars in cutaneous medicine and surgery
pub_type: 杂志文章,评审
doi:10.1016/s1085-5629(00)80025-5
更新日期:2000-09-01 00:00:00