Abstract:
:Studies of the prevalence of atopic dermatitis (AD) have provided insights into associated environmental risk factors, demonstrating the complex interactions between the presence of filaggrin (FLG) gene defects and environment. Among other important findings is that elevated transepidermal water loss (TEWL) in newborns is a strong predictor of AD, regardless of FLG status. Recently recognized predictors of disease course and severity include onset of AD signs and symptoms before 12 months of age and the presence of an FLG mutation and concomitant immunoglobulin E sensitization early in life. Semin Cutan Med Surg 35(supp5):S84-S88.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Simpson EL Md McR,Irvine AD Md,Eichenfield LF Md,Friedlander SF Mddoi
10.12788/j.sder.2016.041subject
Has Abstractpub_date
2016-06-01 00:00:00pages
S84-8issue
5 Suppleissn
1085-5629issn
1558-0768journal_volume
35pub_type
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