Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis.

Abstract:

:Studies of the prevalence of atopic dermatitis (AD) have provided insights into associated environmental risk factors, demonstrating the complex interactions between the presence of filaggrin (FLG) gene defects and environment. Among other important findings is that elevated transepidermal water loss (TEWL) in newborns is a strong predictor of AD, regardless of FLG status. Recently recognized predictors of disease course and severity include onset of AD signs and symptoms before 12 months of age and the presence of an FLG mutation and concomitant immunoglobulin E sensitization early in life. Semin Cutan Med Surg 35(supp5):S84-S88.

journal_name

Semin Cutan Med Surg

authors

Simpson EL Md McR,Irvine AD Md,Eichenfield LF Md,Friedlander SF Md

doi

10.12788/j.sder.2016.041

subject

Has Abstract

pub_date

2016-06-01 00:00:00

pages

S84-8

issue

5 Suppl

eissn

1085-5629

issn

1558-0768

journal_volume

35

pub_type

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