Abstract：
:Perioral dermatitis is a unique skin disorder of childhood. Its exact origin is unknown; it is probably an idiosyncratic response to exogenous factors such as the use of a topical fluorinated corticosteroid or other substances on the face. It is uncommon but not rare. The age of affected children has ranged from 7 months to 13 years, with the median being in the prepubertal period. Boys and girls, blacks and whites are equally affected. Clinical features include the following: (1) absence of systemic symptoms; (2) periorificial distribution (perioral, perinasal, periorbital); (3) skin lesions that consist of flesh colored or erythematous inflammed papules, micronodules, and rare pustules; and (4) variable pruritus. Laboratory tests are negative. Histologically, it is indistinguishable from rosacea; there is a superficial perifollicular granuloma consisting of epitheliod cells, and lymphohistiocytic infiltrate, with occasional giant cells. The disease waxes and wanes for weeks and months. Treatment consists of discontinuing topical fluorinated corticosteroid use if any, and using topical metronidazole alone or in combination with either oral tetracycline or erythromycin depending on the child's age. A low-potency topical steroid may also be used to suppress the inflammation and to wean off the strong steroid. Perioral dermatitis in childhood is probably a juvenile form of rosacea.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Laude TA,Salvemini JNdoi
10.1016/s1085-5629(99)80018-2subject
Has Abstractpub_date
1999-09-01 00:00:00pages
206-9issue
3eissn
1085-5629issn
1558-0768pii
S1085-5629(99)80018-2journal_volume
18pub_type
杂志文章,评审abstract：:This review highlights important considerations in obtaining good skin biopsy specimens to optimize results of direct immunofluorescence (IF) studies and also summarizes the various patterns of cutaneous IF deposition and their associated diagnoses. IF findings of immunobullous diseases, lupus erythematosus, vasculiti...
journal_title：Seminars in cutaneous medicine and surgery
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abstract：:This article discusses the approach to the acute, generalized, blistering patient from the perspective of the dermatologic consultant. Initially, a case is presented, followed by a discussion of the relevant evaluation, differential diagnosis, and treatment options. ...
journal_title：Seminars in cutaneous medicine and surgery
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abstract：:Lasers frequently are used by dermatologists for their multiple aesthetic applications, but they also can be used to treat a variety of medical dermatology conditions. Conditions such as acne vulgaris, psoriasis, and vitiligo can all be successfully treated with laser, thereby providing the patient with additional the...
journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
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doi：10.1016/j.sder.2011.11.003
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abstract：:This is a very exciting time in cutaneous laser surgery with an ever-expanding therapeutic armamentarium and an increased sophistication of available technology. These recent trends have allowed for both a rapid development of interest and exploration of laser-assisted drug delivery and its potential applications. We ...
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journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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更新日期：2009-09-01 00:00:00
abstract：:Psoriasis is now recognized as an immunologically mediated systemic disease that may be expressed in cutaneous and joint symptoms. Medications that were once thought to control psoriasis by reducing keratinocyte proliferation are now known to act on immunologic pathways. In recent years, the emerging understanding of ...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
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abstract：:Dermatologists will enter into a number of different contracts during their professional careers. It is important that in each agreement they enter, dermatologists reap the benefits that they aspire for and understand the consequences of each provision. This article addresses just a few of the different issues that ar...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2005.05.004
更新日期：2005-09-01 00:00:00
abstract：:Patients with renal failure, usually end-stage renal disease (ESRD), commonly are afflicted by severe pruritus. The pathogenesis of ESRD pruritus is unknown, but improving the quality of dialysis can reduce the prevalence and severity of ESRD pruritus. Topical and systemic agents as well as broadband ultraviolet photo...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2011.04.005
更新日期：2011-06-01 00:00:00
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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更新日期：2003-03-01 00:00:00
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
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更新日期：2016-06-01 00:00:00
abstract：:Melanoma is a particularly aggressive type of skin cancer, and its incidence has been increasing steadily since the 1970s. This article will review the extensive epidemiologic data demonstrating that ultraviolet radiation (UVR) exposure, from the sun or artificial tanning beds, is the most important environmental risk...
journal_title：Seminars in cutaneous medicine and surgery
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更新日期：2011-12-01 00:00:00
abstract：:The term bed bug is applied to 2 species of genus Cimex: lectularius describes the common or temperate bed bug, and hemipterus its tropical cousin. Cimex lectularius is aptly named; its genus and species derive from the Latin words for bug and bed, respectively. Though the tiny pest is receiving increased public atten...
journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
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更新日期：2007-03-01 00:00:00
abstract：:The pathophysiology of atopic dermatitis (AD) is complex, and future treatment options will likely be incorporated in a multimodal approach to management. The new, directed therapies that have been developed will likely be used in conjunction with concomitant continuous or intermittent use of standard therapies; the g...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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更新日期：1998-12-01 00:00:00
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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更新日期：1996-12-01 00:00:00
abstract：:One of the most interesting medical conditions that now afflicts the baby boomer generation is photoaging. Clinical signs of photoaging of the skin include rhytids, lentigines, keratoses, telangiectasia, loss of translucency, loss of elasticity, and sallow color. A systematic classification of patient photoaging types...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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更新日期：1996-09-01 00:00:00
abstract：:The ThermaCool TC system is a radiofrequency device capable of delivering higher energy fluences to a greater volume of tissue than nonablative lasers, with no epidermal injury. It has been successful in treating periorbital rhytides and lifting eyebrows. Given these positive finding for treatment of the upper face, t...
journal_title：Seminars in cutaneous medicine and surgery
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journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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更新日期：2013-06-01 00:00:00
abstract：:Hair shaft abnormalities are fascinating and can provide a diagnostic challenge. Current knowledge of structural changes in hair has been amplified by scanning and transmission electron microscopy (SEM and TEM). Dermatologists using the light microscope and polarization in the office can diagnose the great majority of...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
doi：10.1016/j.sder.2006.01.004
更新日期：2006-03-01 00:00:00
abstract：:Cutaneous basal and squamous cell carcinomas are among the most frequent malignancies in the white population, with the annual incidence estimates ranging from 1 million to 3.5 million cases in the United States. These tumors can occur either sporadically or in the context of hereditary genodermatoses with cancer pred...
journal_title：Seminars in cutaneous medicine and surgery
pub_type： 杂志文章,评审
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更新日期：2012-12-01 00:00:00
