Treatment strategies for atopic dermatitis: optimizing the available therapeutic options.

Abstract:

:Bathing and moisturization to control dryness, applications of topical anti-inflammatory agents (including corticosteroids and calcineurin inhibitors [TCIs]) to control flares, minimization of the risk for infection, and relief of pruritus are the cornerstones of effective therapy for atopic dermatitis. Education of parents and patients is crucial to enhance adherence. Strategies for reduced Staphylococcus aureus colonization may help control re-emergence of flares following cessation of antimicrobial treatment for infection; these include dilute bleach baths and minimizing the risk for contamination of topical agents. In severe, refractory cases, more aggressive therapy with systemic immunosuppressants may be considered, but appropriate laboratory testing must be included as part of patient monitoring during treatment. The value of adjuvant therapy with wet wraps to "cool down" particularly erythematous and pruritic flares is becoming increasingly recognized.

journal_name

Semin Cutan Med Surg

authors

Paller AS,Simpson EL,Eichenfield LF,Ellis CN,Mancini AJ

doi

10.1016/j.sder.2012.07.004

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

S10-7

issue

3 Suppl

eissn

1085-5629

issn

1558-0768

journal_volume

31

pub_type

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