Ustekinumab for the treatment of psoriasis: an evidence update.

Abstract:

:Ustekinumab is an interleukin-12/23 inhibitor used for the treatment of moderate-to-severe psoriasis. Here, we review new evidence since ustekinumab was licensed for relative efficacy in comparison with other biologic therapies from head-to-head randomized controlled trials and network meta-analyses for the treatment of psoriasis. We also review observational data emerging from psoriasis registries reporting the effectiveness and safety of ustekinumab. Overall, new evidence suggests that ustekinumab has a favorable balance between efficacy/effectiveness, safety, and tolerability and should remain a first-line biologic therapy option for patients with severe psoriasis at present.

journal_name

Semin Cutan Med Surg

authors

Yiu ZZ,Warren RB

doi

10.12788/j.sder.2018.040

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

143-147

issue

3

eissn

1085-5629

issn

1558-0768

journal_volume

37

pub_type

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