Biology of the hair follicle and mechanisms of nonscarring and scarring alopecia.

abstract：:The pathophysiology of atopic dermatitis (AD) is complex, and future treatment options will likely be incorporated in a multimodal approach to management. The new, directed therapies that have been developed will likely be used in conjunction with concomitant continuous or intermittent use of standard therapies; the g...

journal_title：Seminars in cutaneous medicine and surgery

authors： Friedlander SF Md,Simpson EL Md McR,Irvine AD Md,Eichenfield LF Md

更新日期：2016-06-01 00:00:00

abstract：:Soft tissue augmentation has become increasingly important as more individuals seek aesthetic improvement without major surgical procedures. The choice of an appropriate subcutaneous implant, whether solid or injectable, requires a thorough understanding of the materials available. This review of the literature addres...

journal_title：Seminars in cutaneous medicine and surgery

authors： Krauss MC

更新日期：1999-06-01 00:00:00

abstract：:Spitz nevus (SN) and Spitzoid malignant melanoma (SMM) represent benign and malignant counterparts at both ends of the spectrum of Spitzoid lesions. Atypical Spitzoid neoplasm (ASN) is a poorly defined and characterized category of melanocytic tumors with histologic features of both benign Spitz nevi and malignant mel...

journal_title：Seminars in cutaneous medicine and surgery

authors： Miteva M,Lazova R

更新日期：2010-09-01 00:00:00

abstract：:Idiosyncratic reactions (type B) are a major complication of drug therapy, because they are related to both the drug and to individual factors in the host. In comparison with other organs, the skin is quite frequently a target of allergic reactions, which are mainly elicited by small molecular weight compounds. This i...

journal_title：Seminars in cutaneous medicine and surgery

authors： Merk HF,Hertl M

更新日期：1996-12-01 00:00:00

abstract：:Cutaneous fibrosis is an integral component of a variety of human disorders including keloids, hypertrophic scar, and most notably, scleroderma. Each has its own etiology and unique clinical characteristics, but all involve the dysregulation of connective tissue metabolism, in particular, the activation of dermal fibr...

journal_title：Seminars in cutaneous medicine and surgery

authors： Liu B,Connolly MK

更新日期：1998-03-01 00:00:00

abstract：:In recent years, DNA microarray technology has been used for the analysis of gene expression patterns in a variety of skin diseases, including malignant melanoma, psoriasis, lupus erythematosus, and systemic sclerosis. Many of the studies described herein confirmed earlier results on individual genes or functional gro...

journal_title：Seminars in cutaneous medicine and surgery

authors： Kunz M

更新日期：2008-03-01 00:00:00

abstract：:Phototherapeutic modalities, including narrowband-UVB, broadband-UVB, PUVA photochemotherapy, and excimer laser therapy are valuable tools that can be used for photoresponsive dermatoses in children. As a systematically safer alternative compared with internal agents, including the prebiologic and biological therapies...

journal_title：Seminars in cutaneous medicine and surgery

authors： Pugashetti R,Koo J

更新日期：2010-06-01 00:00:00

abstract：:There are certain disorders of hyper- and hypopigmentation that are more common in children with skin of color. It is imperative that practitioners can swiftly and accurately diagnose these pigmentary disorders to prevent delay in treatment and enhance quality of life. Pigmentary disorders have many etiologies and may...

journal_title：Seminars in cutaneous medicine and surgery

authors： Ascha M,Irfan M

更新日期：2016-12-01 00:00:00

abstract：:This article discusses the approach to the acute, generalized, blistering patient from the perspective of the dermatologic consultant. Initially, a case is presented, followed by a discussion of the relevant evaluation, differential diagnosis, and treatment options. ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Carr DR,Houshmand E,Heffernan MP

更新日期：2007-09-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic skin condition affecting children and adults, with a significant negative impact on patient and caregiver quality of life (QOL). Although effective treatments for AD are available, outcomes are often limited by poor adherence to treatment plans. Effective patient and caregiver educa...

journal_title：Seminars in cutaneous medicine and surgery

authors： LeBovidge J,Borok J,Udkoff J,Yosipovitch G,Eichenfield LF

更新日期：2017-09-01 00:00:00

abstract：:The last decade has witnessed a significant advance in the management of refractory moderate-to-severe psoriasis. This advance is the introduction of biological therapies to clinical practice. Three classes of biological therapies have been used. Of the first 2 classes to be introduced, the T-cell inhibitors and tumor...

journal_title：Seminars in cutaneous medicine and surgery

authors： Warren RB,Griffiths CE

更新日期：2010-03-01 00:00:00

abstract：:Prognosis and survival for patients diagnosed with melanoma depends on a number of interrelated factors, including histological, clinical, immunologic, and surgical parameters. Tumor thickness and depth of invasion is the most important prognostic factor, and helps to guide treatment and management plans. Besides tumo...

journal_title：Seminars in cutaneous medicine and surgery

authors： Brown M

更新日期：1997-06-01 00:00:00

abstract：:Atopic dermatitis (AD) is a chronic, pruritic, inflammatory skin condition that is associated with immune dysregulation and epidermal barrier dysfunction. The imbalance of the Th2 and Th1 pathways and their associated cytokines in AD presents as one facet of the pathogenic mechanisms. Changes in the T-cell populations...

journal_title：Seminars in cutaneous medicine and surgery

authors： Harskamp CT,Armstrong AW

更新日期：2013-09-01 00:00:00

abstract：:Closing surgical defects of the external ear poses unique challenges because of the convoluted shape and thin tethered skin. Choice of repair is often dictated by the site of the wound. If the defect is central and anterior with intact cartilage, most defects will do well by second intention healing or grafting. If th...

journal_title：Seminars in cutaneous medicine and surgery

authors： Olbricht S,Liégeois NJ

更新日期：2003-12-01 00:00:00

abstract：:Lasers, both in single and multiple wavelength designs, have recently been introduced to enhance the results of liposuction. Safe parameters of fluence and temperature have not yet been described. In this study, I describe a series of laser lipolysis patients treated with a dual wavelength (1064/1319 nm) laser where i...

journal_title：Seminars in cutaneous medicine and surgery

authors： Salzman MJ

更新日期：2009-12-01 00:00:00

abstract：:The history of burn scars can best be found in military medical history. The care of wounded soldiers documented in the Illiad reflected the trauma of the weapons of war, arrow, spear, sword, and ax. The introduction of gunpowder in the 14th century, increasingly sophisticated explosives, and in modern times, petroleu...

journal_title：Seminars in cutaneous medicine and surgery

authors： Petro JA

更新日期：2015-03-01 00:00:00

abstract：:Perioral dermatitis is a unique skin disorder of childhood. Its exact origin is unknown; it is probably an idiosyncratic response to exogenous factors such as the use of a topical fluorinated corticosteroid or other substances on the face. It is uncommon but not rare. The age of affected children has ranged from 7 mon...

journal_title：Seminars in cutaneous medicine and surgery

authors： Laude TA,Salvemini JN

更新日期：1999-09-01 00:00:00

abstract：:Dermatologic manifestations are among the most common signs of systemic lupus erythematosus (SLE). The Hopkins Lupus Cohort study is a prospective study in which patients with SLE are seen on a quarterly basis for measurement of disease activity, laboratory tests, and assessment of morbidity and quality of life. This ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Petri M

更新日期：1998-09-01 00:00:00

abstract：:Cutaneous basal and squamous cell carcinomas are among the most frequent malignancies in the white population, with the annual incidence estimates ranging from 1 million to 3.5 million cases in the United States. These tumors can occur either sporadically or in the context of hereditary genodermatoses with cancer pred...

journal_title：Seminars in cutaneous medicine and surgery

authors： Nikolaou V,Stratigos AJ,Tsao H

更新日期：2012-12-01 00:00:00

abstract：:Oral mucosal bullous/desquamative/ulcerative diseases involve immunopathological mechanisms that account for loss of adhesion between contiguous keratinocytes or to structures within the basal lamina. Some are antibody mediated, in which specific adhesion molecules of the desmosome, hemidesmosome, and basement membran...

journal_title：Seminars in cutaneous medicine and surgery

authors： Eversole LR

更新日期：1997-12-01 00:00:00

abstract：:Dermoscopy increases the clinician's diagnostic accuracy by as much as 30% over that of unaided visual clinical inspection alone and has been confirmed in 3 separate evidence-based publications using a meta-analysis of the literature. It can be viewed as an in vivo bridge between clinical morphology and histopathology...

journal_title：Seminars in cutaneous medicine and surgery

authors： Braun RP,Rabinovitz H,Tzu JE,Marghoob AA

更新日期：2009-09-01 00:00:00

abstract：:One of the most interesting medical conditions that now afflicts the baby boomer generation is photoaging. Clinical signs of photoaging of the skin include rhytids, lentigines, keratoses, telangiectasia, loss of translucency, loss of elasticity, and sallow color. A systematic classification of patient photoaging types...

journal_title：Seminars in cutaneous medicine and surgery

authors： Glogau RG

更新日期：1996-09-01 00:00:00

abstract：:The term bed bug is applied to 2 species of genus Cimex: lectularius describes the common or temperate bed bug, and hemipterus its tropical cousin. Cimex lectularius is aptly named; its genus and species derive from the Latin words for bug and bed, respectively. Though the tiny pest is receiving increased public atten...

journal_title：Seminars in cutaneous medicine and surgery

authors： Foulke GT,Anderson BE

更新日期：2014-09-01 00:00:00

abstract：:The development of fractional photothermolysis is a milestone in the history of laser technology and cutaneous resurfacing. Based on the concept that skin is treated in a fractional manner, where narrow cylinders of tissue are thermally heated and normal adjacent skin is left unaffected, the fractional devices have sh...

journal_title：Seminars in cutaneous medicine and surgery

authors： Saedi N,Jalian HR,Petelin A,Zachary C

更新日期：2012-06-01 00:00:00

abstract：:In an attempt to limit the prolonged postoperative healing associated with ablative laser skin resurfacing and in response to growing public interest in less invasive treatment modalities, nonablative laser and light source technology was developed. Over the past few years, several clinical and histologic research stu...

journal_title：Seminars in cutaneous medicine and surgery

authors： Alster TS,Lupton JR

更新日期：2002-12-01 00:00:00

abstract：:Topical retinoic acid was introduced for acne treatment three decades ago. Since that time, researchers have discovered thousands of retinoids, originally defined as chemical analogs of vitamin A. After the identification of nuclear retinoid receptors in 1987, the definition of this class expanded to include molecules...

journal_title：Seminars in cutaneous medicine and surgery

authors： Bershad S

更新日期：2001-09-01 00:00:00

abstract：:In 1996, oral terbinafine joined itraconazole and fluconazole on the short list of systemic medications that could be used to treat onychomycosis (although fluconazole was not approved for this indication by the US Food and Drug Administration [FDA], it was commonly used for this purpose). In 1999, ciclopirox was the ...

journal_title：Seminars in cutaneous medicine and surgery

authors： Rosen T,Stein Gold LF

更新日期：2016-03-01 00:00:00

abstract：:This review highlights melanoma trends observed among African-, Asian-, Latino- and Native-American populations. Melanoma is the most lethal form of skin cancer, accounting for about 75% of all skin cancer deaths. Generally, incidence rates increase with age, peak after age 40, and are greater in men than women. Howev...

journal_title：Seminars in cutaneous medicine and surgery

authors： Shoo BA,Kashani-Sabet M

更新日期：2009-06-01 00:00:00

abstract：:Nonpharmacologic management of psychodermatologic conditions includes both structured and unstructured interventions that may ameliorate skin disorders, reduce psychological distress, and improve the functional status of the affected individual. Nonpharmacologic techniques are often referred to as psychocutaneous inte...

journal_title：Seminars in cutaneous medicine and surgery

authors： Fried RG

更新日期：2013-06-01 00:00:00

abstract：:Infections with organisms of the genus Bartonella, for many years important only in South and Central America, have assumed significance in developing countries, especially in conjunction with the advent of the pandemic of the human immunodeficiency virus infection. New molecular and culture techniques have determined...

journal_title：Seminars in cutaneous medicine and surgery

authors： Wong R,Tappero J,Cockerell CJ

更新日期：1997-09-01 00:00:00