Abstract：
:Food intake and, subsequently, body weight are influenced by endogenous opioids acting in the central nervous system. Agonists for the opioid receptor increase food intake, whereas antagonists reduce food intake. Body weight, however, is the result of food consumed and energy expended. Although much has been reported about the effect of opioid antagonism on food intake, less has been reported about its effect on energy expended. This study investigated the effect of selective antagonism of the kappa opioid receptor on food intake, body weight, and indicators of energy expenditure in male obese Zucker rats (n=10). Energy expenditure was measured by indirect calorimetry, whereas general activity and body temperature were measured by implanted radio frequency telemetry. Central administration of 30 microg of the kappa opioid receptor (KOR) antagonist norbinaltorphamine resulted in a significant 34% reduction in food intake (p =.001), a small reduction in body weight, a reduction in resting energy expenditure (p = .06), a reduction in respiratory quotient (p =.06), a 14% reduction in general activity, and a reduction in core body temperature. Reduction in body weight as a result of KOR inhibition in this study was related to a decrease in food intake but not related to an increase in energy expended or activity.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Jarosz PAdoi
10.1177/1099800406298774subject
Has Abstractpub_date
2007-04-01 00:00:00pages
294-9issue
4eissn
1099-8004issn
1552-4175pii
8/4/294journal_volume
8pub_type
杂志文章abstract：:The purpose of this study was to describe the sleep patterns and fatigue of both mothers and fathers before and after childbirth. The authors used wrist actigraphy and questionnaires to estimate sleep and fatigue in 72 couples during their last month of pregnancy and 1st month postpartum. Both parents experienced more...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800403262142
更新日期：2004-04-01 00:00:00
abstract：:Over the last 10 years, interest in the analysis of saliva as a biomarker for a variety of systemic diseases or for potential disease has soared. There are numerous advantages to using saliva as a biological fluid, particularly for nurse researchers working with vulnerable populations, such as frail older adults. Most...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800411404211
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:Application of a thermal stimulus is a common procedure used to promote venodilation for peripheral intravenous cannulation (PIVC); however, the effects of thermal stimulation on the duration of venodilation and skin temperature of the forearm are unclear. AIM:To investigate the duration of venodilation ind...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416651145
更新日期：2017-03-01 00:00:00
abstract：:Approximately half of the Canadian adults have sedentary lifestyles that increase their risk of developing cardiovascular disease (CVD). Women are 10 times more likely to die from CVD than from any other disease. Their risk almost doubles with the onset of menopause, which may result in increased body iron burden and ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800413501717
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:This study examined adherence to a personalized, community-based exercise intervention by sedentary adolescents with type 1 or type 2 diabetes or those with obesity. RESEARCH DESIGN AND METHODS:We conducted a pretest-posttest investigation to explore the application of an individualized exercise prescription...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800413500064
更新日期：2014-01-01 00:00:00
abstract：:Sleep disturbance is a common and disturbing symptom in military personnel, with many individuals progressing to the development of insomnia, which is characterized by increased arousals, wakefulness after sleep onset, and distorted sleep architecture. The molecular mechanisms underlying insomnia remain elusive, limit...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800415575343
更新日期：2015-07-01 00:00:00
abstract：:The purposes of this quasi-experimental pilot study were to determine adherence to a 12-week group-based moderate-intensity walking program for sedentary adult outpatients with serious and persistent mental illness and to examine change from baseline to after the walking program in health status (mental and physical h...
journal_title：Biological research for nursing
pub_type： 临床试验,杂志文章
doi：10.1177/1099800405278116
更新日期：2005-10-01 00:00:00
abstract：:Vaccination is one of our most powerful antiviral strategies. Despite the emergence of deadly viruses such as Ebola virus, vaccination efforts have focused mainly on childhood communicable diseases. Although Ebola virus was once believed to be limited to isolated outbreaks in distant lands, forces of globalization pot...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800403252574
更新日期：2003-04-01 00:00:00
abstract：:The aim of this study was to investigate the effects of a resistance training program (RTP) in older overweight women (OOW) using two different types of elastic devices. METHODS:This study was a randomized controlled trial with pre- and postintervention measures. Participants included OOW, aged 60-85 years, with no m...
journal_title：Biological research for nursing
pub_type： 杂志文章,随机对照试验
doi：10.1177/1099800418757676
更新日期：2018-05-01 00:00:00
abstract：:Central nervous system (CNS)-directed treatment for acute lymphoblastic leukemia, used to prevent disease recurrence in the brain, is essential for survival. Systemic and intrathecal methotrexate, commonly used for CNS-directed treatment, have been associated with cognitive problems during and after treatment. The cor...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416644780
更新日期：2016-10-01 00:00:00
abstract：:Caring, a core tenet of nursing practice, grew out of a holistic approach. Nurse theorists often note the establishment of a therapeutic relationship as the beginning point of caring, with subsequent nursing interventions reliant upon this relationship for effectiveness. Relational exchange serves as a source of eithe...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800412450505
更新日期：2012-10-01 00:00:00
abstract：:The purpose of this study was to evaluate for differences in variations in pro- and anti-inflammatory cytokine genes between participants who were classified as having low and high levels of morning and evening fatigue and to evaluate for differences in phenotypic characteristics between these two groups. In a sample ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414534313
更新日期：2015-03-01 00:00:00
abstract：:Cytokines such as angiogenin (ANG) and interleukin (IL-8) have been shown to be related to depressive symptoms and inflammatory diseases like coronary heart disease. They may thus be used as stress biomarkers to identify and prevent health problems. To investigate the relationship between cytokines and nurses' job-rel...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800408323219
更新日期：2008-10-01 00:00:00
abstract：:Self-management programs that include cognitive behavioral strategies have been shown to improve gastrointestinal (GI) symptoms, psychological distress, and quality of life (QoL) in persons with irritable bowel syndrome (IBS). However, less is known about the physiological impact of such a change. As part of a randomi...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800411414047
更新日期：2013-01-01 00:00:00
abstract：RESULTS:hs-CRP correlated significantly with SLEDAI-2K (p = .036), SDI (p = .00), anti-dsDNA titers (p = .034), diabetes (p = .005), and obesity (p = .027). hs-CRP and Hcy correlated with triglyceride (TG) levels (p = .032 and p < .001, respectively), TG/high-density lipoprotein cholesterol index (p = .020 and p = .001...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800419889192
更新日期：2020-04-01 00:00:00
abstract：:Night-shift workers are prone to sleep deprivation, misalignment of circadian rhythms, and subsequent sleepiness and sleep-related performance deficits. The purpose of this narrative systematic review is to critically review and synthesize the scientific literature regarding improvements in sleepiness and sleep-relate...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800413476571
更新日期：2014-04-01 00:00:00
abstract：:Delirium is a serious complication of acute illness. Little is known, however, regarding the neurobiology of delirium, largely due to challenges in studying the complex inpatient population. Neuroimaging is one noninvasive method that can be used to study structural and functional brain abnormalities associated with d...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800419849489
更新日期：2019-07-01 00:00:00
abstract：:Paclitaxel (PAC) treatment is associated with persistent, debilitating neuropathic pain that affects the hands and feet. Female sex and biological stress responsivity are risk factors for persistent pain, but it is unclear whether these important biologically based factors confer risk for PAC-induced neuropathic pain....
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800415609418
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Incidence rates of both type 1 and type 2 diabetes mellitus (DM) are increasing in youth and may eventually contribute to premature heart disease in early adulthood. This investigation explored the influence of type of diabetes, gender, body mass index (BMI), metabolic control (HbA1c), exercise beliefs and p...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800405275202
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVES:The objectives of this study were to determine the change in gene expression between two time points following stroke and to identify biomarkers of stroke recovery through gene expression profiling and pathway analysis. METHODS:Peripheral blood was collected from 34 ischemic stroke patients (confirmed by ma...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414546492
更新日期：2015-05-01 00:00:00
abstract：:Scientists and clinicians frequently use immunological methods (IMs) to investigate complex biological phenomena. Commonly used IMs include immunocytochemistry (IC), enzyme-linked immunosorbent assays (ELISA) and flow cytometry. Each of these methodologies exploits a common principle in IMs -the binding of an antibody...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800411402494
更新日期：2011-07-01 00:00:00
abstract：:Maternal posturing, in which a pregnant or laboring woman assumes specific postures with the intention of altering the position and/or presentation of the fetus within the uterus, is a safe alternative to operative procedures recommended in cases of fetal malpositions and malpresentations. Clinicians and researchers a...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800404268318
更新日期：2004-10-01 00:00:00
abstract：:This article explores ethical concerns and emerging dilemmas associated with the proliferation of information resulting from the extraordinary advances in molecular genetics. It provides an overview of the ethical and legal challenges associated with predictive testing for inherited disease currently being addressed i...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/109980040100300104
更新日期：2001-07-01 00:00:00
abstract：:Nausea and vomiting are the most common side effects of antineoplastic chemotherapy. However, only a small number of studies have been conducted in Taiwan to determine the efficacy of acupressure in treating these side effects in cancer patients receiving chemotherapy. In this quasi-experimental study, we aimed to exp...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416683801
更新日期：2017-03-01 00:00:00
abstract：:Postpartum depression (PPD) affects at least 10% to 15% of postpartum women, including more than 600,000 American mothers in 2003 alone. Dramatic changes in the hypothalamic-pituitary-adrenal (HPA) system in the transition from pregnancy to postpartum coupled with research on the psychobiology of depression provided t...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800406294598
更新日期：2007-01-01 00:00:00
abstract：:Since the completion of the Human Genome Project, much has been uncovered about inheritance of various illnesses and disorders. There are two main types of inheritance: Mendelian and non-Mendelian. Mendelian inheritance includes autosomal dominant, autosomal recessive, X-linked, and Y-linked inheritance. Non-Mendelian...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800417708616
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:To investigate the prevalence and patterns of and factors associated with hyperphagic behavior in Taiwanese patients with dementia living at home. METHODS:A cross-sectional and correlational design was used. A total of 104 patients with dementia and their primary caregivers were recruited from the geriatric,...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414562025
更新日期：2015-10-01 00:00:00
abstract：:For precision health care to be successful, an in-depth understanding of the biological mechanisms for symptom development and severity is essential. Omics-based research approaches facilitate identification of the biological underpinnings of symptoms. We reviewed literature for omics-based approaches and exemplar sym...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800417751069
更新日期：2018-03-01 00:00:00
abstract：:Benefits of daily physical activity are well known, but there are limited data to describe physical activity in heart failure patients who receive cardiac resynchronization therapy devices. The purpose of this pilot study was to evaluate changes in physical activity (PA) levels before and 3 months after Cardiac Resync...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800413481619
更新日期：2014-01-01 00:00:00
abstract：:Interpretation of changes in health and health care utilization patterns across the life span depends on an understanding of the effects of age, period, and cohort. The purpose of this article is to illustrate differences among three generations of women in demographic factors, health risk factors, and health status i...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800410373804
更新日期：2010-10-01 00:00:00
