Abstract:
:Since the completion of the Human Genome Project, much has been uncovered about inheritance of various illnesses and disorders. There are two main types of inheritance: Mendelian and non-Mendelian. Mendelian inheritance includes autosomal dominant, autosomal recessive, X-linked, and Y-linked inheritance. Non-Mendelian inheritance includes mitochondrial and multifactorial inheritance. Nurses must understand the types of inheritance in order to identify red flags that may indicate the possibility of a hereditary disorder in a patient or family.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Aiello LB,Chiatti BDdoi
10.1177/1099800417708616subject
Has Abstractpub_date
2017-07-01 00:00:00pages
465-472issue
4eissn
1099-8004issn
1552-4175journal_volume
19pub_type
杂志文章abstract::MicroRNAs (miRs) are epigenetic regulators of messenger RNAs' (mRNA) expression of polypeptides. As such, miRs represent an intriguing mechanism by which gene-environment interactions are hypothesized to occur on the level of epigenetic control over gene expression. In addition to promising findings from in vitro stud...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800411430380
更新日期:2013-04-01 00:00:00
abstract::For precision health care to be successful, an in-depth understanding of the biological mechanisms for symptom development and severity is essential. Omics-based research approaches facilitate identification of the biological underpinnings of symptoms. We reviewed literature for omics-based approaches and exemplar sym...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800417751069
更新日期:2018-03-01 00:00:00
abstract::The current study was performed to evaluate the antinociceptive and antiedematogenic properties of andrographolide isolated from the leaves of Andrographis paniculata using two animal models. Antinociceptive activity was evaluated using the acetic acid- induced writhing and the hot-plate tests, while antiedematogenic ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800409343311
更新日期:2010-01-01 00:00:00
abstract::The purpose of this study was to describe the sleep patterns and fatigue of both mothers and fathers before and after childbirth. The authors used wrist actigraphy and questionnaires to estimate sleep and fatigue in 72 couples during their last month of pregnancy and 1st month postpartum. Both parents experienced more...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800403262142
更新日期:2004-04-01 00:00:00
abstract:INTRODUCTION:Plasma concentrations of lipids (i.e., total cholesterol, high-density cholesterol, low-density cholesterol, and triglycerides) are amenable to therapeutic intervention and remain important factors for assessing risk of cardiovascular diseases. Some of the observed variability in serum lipid concentrations...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417752246
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:Proinflammatory activity has been suggested as one of the psychophysiological mechanisms responsible for the health risks associated with stress and mood disorders. There have been limited studies evaluating central immune and hypothalamic- pituitary-adrenal (HPA) axis responses to experimental stress in heal...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800410383558
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Many chronic conditions, including heart disease, cancer, and rheumatoid arthritis, are associated with underlying chronic inflammatory processes. Literature reviews have analyzed a variety of integrative therapies and their relationships with chronic inflammation. This systematic review is unique in reporti...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800418820162
更新日期:2019-03-01 00:00:00
abstract::The psychophysiological phenomenon of pain is of tremendous concern to nurses because of its potential to adversely affect the mental, emotional, and physical health of patients. Increasingly appreciated is the ability of pain to influence immune variables including enumerative and functional measures of leukocyte sub...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800405286071
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:Drug addiction is a multifactorial disorder. Researchers have posited that an individual's inherited behavioral propensity or temperament contributes to the disorder by shaping a personality strongly linked with the risk of drug abuse. Further, they hypothesize that the polymorphism of dopamine D2 receptor i...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800411405030
更新日期:2012-04-01 00:00:00
abstract::Fatigue is the most frequently reported symptom by cancer patients. Many of these patients perceive fatigue as the most distressing symptom associated with their illness because it imposes limitations on their physical activity level. Skeletal muscle wasting, which occurs as part of cancer cachexia, is one of the mech...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/109980040100200304
更新日期:2001-01-01 00:00:00
abstract::Cytokines are small signaling proteins released from a variety of cells that influence virtually every aspect of growth and development and every host response to infection, injury, and inflammation. Because of their widespread and potent effects across the life span, cytokines without a doubt influence nursing resear...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/109980040000200105
更新日期:2000-07-01 00:00:00
abstract::The American Academy of Pediatrics recently removed nicotine from the list of drugs contraindicated during breastfeeding. The objective of this study was to evaluate the feasibility of determining the effect of a smoking hygiene intervention on infants of breastfeeding mothers who smoke cigarettes. An experimental des...
journal_title:Biological research for nursing
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1099800406290643
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:There are documented associations between elevated maternal corticotropin-releasing hormone (CRH) levels and adverse pregnancy outcomes. However, reports of these findings often lack sufficient detail and rationale regarding the bioassay methodology. This shortcoming can be problematic for researchers who do...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800408320970
更新日期:2008-07-01 00:00:00
abstract::Maternal posturing, in which a pregnant or laboring woman assumes specific postures with the intention of altering the position and/or presentation of the fetus within the uterus, is a safe alternative to operative procedures recommended in cases of fetal malpositions and malpresentations. Clinicians and researchers a...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800404268318
更新日期:2004-10-01 00:00:00
abstract::Benefits of daily physical activity are well known, but there are limited data to describe physical activity in heart failure patients who receive cardiac resynchronization therapy devices. The purpose of this pilot study was to evaluate changes in physical activity (PA) levels before and 3 months after Cardiac Resync...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800413481619
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to determine the change in gene expression between two time points following stroke and to identify biomarkers of stroke recovery through gene expression profiling and pathway analysis. METHODS:Peripheral blood was collected from 34 ischemic stroke patients (confirmed by ma...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800414546492
更新日期:2015-05-01 00:00:00
abstract:PURPOSE:In recent years, researchers have noted an "obesity paradox," where individuals with obesity survive sepsis at higher rates than their nonobese counterparts. This systematic review summarizes the literature on studies examining the association between obesity and 1-year mortality among patients admitted with se...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800419876070
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Depression and inflammation are concomitantly elevated in patients with lung cancer and may have collective survival implications. However, the longitudinal relationship between depression and inflammation in patients with metastatic lung cancer is not fully appreciated. We hypothesized that longitudinal cha...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800420959721
更新日期:2020-09-22 00:00:00
abstract::Survivors of aneurysmal subarachnoid hemorrhage (aSAH) often experience unfavorable functional outcomes that result in a reduced ability to independently perform activities of daily living. The apolipoprotein E gene ( APOE) encodes for a protein known to facilitate lipid transport and aid in neuronal repair within the...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417746504
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:To explore whether newborns born via Cesarean section have a weaker intraoral vacuum compared with those born vaginally and to determine whether a weaker intraoral vacuum is related to a delayed onset of lactation. METHODS:For this prospective cohort study, 71 mother-infant dyads were enrolled and divided i...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800416636687
更新日期:2016-07-01 00:00:00
abstract::The prevalence of vascular dementia continues to increase with no cure. Thus, it is important identify the aggravating factors of vascular dementia to delay disease progression in patients. Obesity is a well-known risk factor for vascular dementia and causes mild cognitive impairment. In the present study, we evaluate...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800420951633
更新日期:2020-08-26 00:00:00
abstract:PURPOSE:Sleep deficit affects neurobehavioral functioning, reduces attention and cognitive function, and negatively impacts occupational safety. This study investigated selective attention levels of nursing staff on different shifts. METHODS:Using a prospective, randomized parallel group study, selective attention was...
journal_title:Biological research for nursing
pub_type: 杂志文章,随机对照试验
doi:10.1177/1099800412445907
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Leptin and adiponectin, two adipokines involved in glucose and lipid metabolism, have been linked to regulation of growth in early infancy, energy balance, and metabolic disorders in childhood. The aim of this study was to determine if concentrations of leptin and adiponectin could be measured reliably in in...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800420973366
更新日期:2020-11-28 00:00:00
abstract::The purpose of this study was to evaluate for differences in variations in pro- and anti-inflammatory cytokine genes between participants who were classified as having low and high levels of morning and evening fatigue and to evaluate for differences in phenotypic characteristics between these two groups. In a sample ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800414534313
更新日期:2015-03-01 00:00:00
abstract::Sickness behavior is a cluster of symptoms that occur as a response to an infection and alterations in the inflammatory response. Under normal circumstances, sickness behavior is fully reversible once the pathogen has been cleared. Aging and chronic illness such as heart failure are associated with enhanced inflammato...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800412466170
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:Activity restriction (AR), one of the most common interventions used in high-risk pregnancies, may exacerbate loss of bone mass. The purpose of this study was to determine changes over time in bone resorption in hospitalized AR women during late pregnancy. METHODS:This was a short-term prospective study conduc...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800412463120
更新日期:2014-01-01 00:00:00
abstract::Approximately half of the Canadian adults have sedentary lifestyles that increase their risk of developing cardiovascular disease (CVD). Women are 10 times more likely to die from CVD than from any other disease. Their risk almost doubles with the onset of menopause, which may result in increased body iron burden and ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800413501717
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:The sacral skin of bedridden older patients often develops a dysbiotic condition. To clarify whether the condition changes or is sustained over time, we analyzed the skin microbiome and the skin physiological functions of the sacral skin in patients who completed our 2017 study. METHODS:In 2019, we collected...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800420941151
更新日期:2021-01-01 00:00:00
abstract::Preterm birth (PTB; spontaneous delivery prior to 37 weeks gestation) affects one out of eight infants born in the United States and is the most common cause of neonatal morbidity and mortality. Although the pathogenesis of PTB is multifactorial, a growing body of literature supports the hypothesis that one cause of P...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800409344620
更新日期:2010-04-01 00:00:00
abstract::Night-shift workers are prone to sleep deprivation, misalignment of circadian rhythms, and subsequent sleepiness and sleep-related performance deficits. The purpose of this narrative systematic review is to critically review and synthesize the scientific literature regarding improvements in sleepiness and sleep-relate...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800413476571
更新日期:2014-04-01 00:00:00