Abstract:
:Fatigue is the most frequently reported symptom by cancer patients. Many of these patients perceive fatigue as the most distressing symptom associated with their illness because it imposes limitations on their physical activity level. Skeletal muscle wasting, which occurs as part of cancer cachexia, is one of the mechanisms that contribute to fatigue. Cancer-induced skeletal muscle wasting may occur despite normal food intake and is not prevented by nutritional supplementation. Evidence suggests that endurance exercise ameliorates cancer-related fatigue. There is no compelling evidence to support that exercise-induced reduction in fatigue is related to preservation of muscle mass. Resistance exercise attenuates muscle wasting associated with a variety of catabolic conditions. However, its effects on cancer-induced muscle wasting have not been adequately studied. This article describes the physiological mechanisms implicated in the induction of cancer-related muscle wasting, summarizes findings from endurance and resistance exercise studies in relation to fatigue and muscle wasting during cancer and selected clinical conditions, and proposes directions for future research.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
al-Majid S,McCarthy DOdoi
10.1177/109980040100200304subject
Has Abstractpub_date
2001-01-01 00:00:00pages
186-97issue
3eissn
1099-8004issn
1552-4175journal_volume
2pub_type
杂志文章,评审abstract::Sleep disturbance is a common and disturbing symptom in military personnel, with many individuals progressing to the development of insomnia, which is characterized by increased arousals, wakefulness after sleep onset, and distorted sleep architecture. The molecular mechanisms underlying insomnia remain elusive, limit...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800415575343
更新日期:2015-07-01 00:00:00
abstract::Approximately half of the Canadian adults have sedentary lifestyles that increase their risk of developing cardiovascular disease (CVD). Women are 10 times more likely to die from CVD than from any other disease. Their risk almost doubles with the onset of menopause, which may result in increased body iron burden and ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800413501717
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Application of a thermal stimulus is a common procedure used to promote venodilation for peripheral intravenous cannulation (PIVC); however, the effects of thermal stimulation on the duration of venodilation and skin temperature of the forearm are unclear. AIM:To investigate the duration of venodilation ind...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800416651145
更新日期:2017-03-01 00:00:00
abstract::Interpretation of changes in health and health care utilization patterns across the life span depends on an understanding of the effects of age, period, and cohort. The purpose of this article is to illustrate differences among three generations of women in demographic factors, health risk factors, and health status i...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800410373804
更新日期:2010-10-01 00:00:00
abstract:INTRODUCTION:Diabetes is a serious health problem affecting approximately 29.1 million individuals in the United States. Another 86 million have prediabetes. The development and implementation of lifestyle modifications such as physical activity for these persons are among the most effective methods for prevention and ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800418767572
更新日期:2018-07-01 00:00:00
abstract::Multiple chemical sensitivity (MCS) is a chronic condition prevalent in women; the symptoms are reproducible with repeated low-level chemical exposure. Evidence gathered through clinical observations suggests that women with MCS may be at risk for autonomic nervous system dysfunction as evidenced by abnormal heart rat...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800408324251
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:The sacral skin of bedridden older patients often develops a dysbiotic condition. To clarify whether the condition changes or is sustained over time, we analyzed the skin microbiome and the skin physiological functions of the sacral skin in patients who completed our 2017 study. METHODS:In 2019, we collected...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800420941151
更新日期:2021-01-01 00:00:00
abstract::The prevalence of obesity and obesity-related illnesses is higher among Hispanics (Latinos) than other racial and ethnic groups, and rates increase exponentially with the number of years living in the United States. Mounting evidence suggests that the origins of many chronic illnesses among disadvantaged minority grou...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800412457017
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Eating disorders are a significant cause of morbidity and mortality. The etiology and maintenance of eating-disorder symptoms are not well understood. Evidence suggests that there may be gustatory alterations in patients with eating disorders. OBJECTIVE:This article systematically reviews research assessing...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800419872824
更新日期:2020-01-01 00:00:00
abstract::Maternal posturing, in which a pregnant or laboring woman assumes specific postures with the intention of altering the position and/or presentation of the fetus within the uterus, is a safe alternative to operative procedures recommended in cases of fetal malpositions and malpresentations. Clinicians and researchers a...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800404268318
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:The purpose of this study was to explore gene expression changes in fatigued men with nonmetastatic prostate cancer receiving localized external beam radiation therapy (EBRT). METHODS:Fatigue was measured in 40 men with prostate cancer (20 receiving EBRT and 20 controls on active surveillance) using the Functi...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800415618786
更新日期:2016-05-01 00:00:00
abstract::For precision health care to be successful, an in-depth understanding of the biological mechanisms for symptom development and severity is essential. Omics-based research approaches facilitate identification of the biological underpinnings of symptoms. We reviewed literature for omics-based approaches and exemplar sym...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800417751069
更新日期:2018-03-01 00:00:00
abstract::Since the completion of the Human Genome Project, much has been uncovered about inheritance of various illnesses and disorders. There are two main types of inheritance: Mendelian and non-Mendelian. Mendelian inheritance includes autosomal dominant, autosomal recessive, X-linked, and Y-linked inheritance. Non-Mendelian...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417708616
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Depression and inflammation are concomitantly elevated in patients with lung cancer and may have collective survival implications. However, the longitudinal relationship between depression and inflammation in patients with metastatic lung cancer is not fully appreciated. We hypothesized that longitudinal cha...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800420959721
更新日期:2020-09-22 00:00:00
abstract:PURPOSE:In recent years, researchers have noted an "obesity paradox," where individuals with obesity survive sepsis at higher rates than their nonobese counterparts. This systematic review summarizes the literature on studies examining the association between obesity and 1-year mortality among patients admitted with se...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800419876070
更新日期:2020-01-01 00:00:00
abstract::Depression increases the risk of adverse cardiac events. Cardiovascular reactivity is defined as the pattern of cardiovascular responses to mental stress. An altered pattern of cardiovascular reactivity is an indicator of subsequent cardiovascular disease. Because depression and adverse cardiac events may have a dose-...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800415596227
更新日期:2016-03-01 00:00:00
abstract::Society has a rapidly growing accumulative sleep debt due to employment obligations and lifestyle choices that limit sleep opportunities. The degree to which poor sleep may set the stage for adverse symptom outcomes among more than 1.7 million persons who will be diagnosed with cancer is not entirely understood. Pacli...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800414539385
更新日期:2015-03-01 00:00:00
abstract::The theoretical constructs of allostasis and allostatic load (AL) have contributed to our understanding of how constantly changing social and environmental factors impact physiological functioning and shape health and aging disparities, particularly along socioeconomic, gendered, racial, and ethnic lines. AL represent...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800412455688
更新日期:2012-10-01 00:00:00
abstract::The primary purpose of this exploratory study was to compare percentages of natural killer (NK) cells and activated NK and T cells, and both cytotoxic and in vitro cytokine production activity in women with and without symptomatic irritable bowel syndrome (IBS). A secondary purpose was to examine the relationships of ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800402004001005
更新日期:2002-07-01 00:00:00
abstract::Vaccination is one of our most powerful antiviral strategies. Despite the emergence of deadly viruses such as Ebola virus, vaccination efforts have focused mainly on childhood communicable diseases. Although Ebola virus was once believed to be limited to isolated outbreaks in distant lands, forces of globalization pot...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800403252574
更新日期:2003-04-01 00:00:00
abstract::This article explores ethical concerns and emerging dilemmas associated with the proliferation of information resulting from the extraordinary advances in molecular genetics. It provides an overview of the ethical and legal challenges associated with predictive testing for inherited disease currently being addressed i...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/109980040100300104
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVE:Although the roles of testosterone and cortisol in various health problems have been extensively investigated, little is known about their associations with health outcomes in mothers and their very-low-birthweight (VLBW) infants when maternal testosterone and cortisol are examined together during the postpar...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417703704
更新日期:2017-07-01 00:00:00
abstract::The purpose of this study was to compare physiological and psychological reactions among Taiwanese women with different degrees of severity of nausea and vomiting (NV) during pregnancy. Based on their scores on the Index of Nausea, Vomiting, and Retching (INVR), 59 pregnant women ≥ 18 years of age, with single gestati...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800410388506
更新日期:2011-10-01 00:00:00
abstract::The purpose of this study was to longitudinally describe changes in heart rate variability (HRV) from 28 to 34 weeks postmenstrual age (PMA). A convenience sample of 31 low-risk preterm infants participated. HRV was quantified using a spectral analysis of heart periods and recorded during seven weekly test sessions fr...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800409341175
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:The Finnmarksløpet dogsled race lasts up to 7 days. Helpers, who keep time, coach, and transport equipment, have to be alert though they have little and fragmented sleep. This study investigated disruptions of the rest-activity rhythm among helpers. METHODS:10 helpers were monitored by actigraph a week befor...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800412475077
更新日期:2014-04-01 00:00:00
abstract::Cytokines such as angiogenin (ANG) and interleukin (IL-8) have been shown to be related to depressive symptoms and inflammatory diseases like coronary heart disease. They may thus be used as stress biomarkers to identify and prevent health problems. To investigate the relationship between cytokines and nurses' job-rel...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800408323219
更新日期:2008-10-01 00:00:00
abstract::Despite high efficacy rates, significant costs and logistical challenges associated with procuring stool from healthy donors for fecal microbiota transplantation (FMT) have presented barriers to broader institutional adoption and limited the availability of this life-saving treatment. Published outcomes for donor scre...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800420941185
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Drug addiction is a multifactorial disorder. Researchers have posited that an individual's inherited behavioral propensity or temperament contributes to the disorder by shaping a personality strongly linked with the risk of drug abuse. Further, they hypothesize that the polymorphism of dopamine D2 receptor i...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800411405030
更新日期:2012-04-01 00:00:00
abstract::Scientists and clinicians frequently use immunological methods (IMs) to investigate complex biological phenomena. Commonly used IMs include immunocytochemistry (IC), enzyme-linked immunosorbent assays (ELISA) and flow cytometry. Each of these methodologies exploits a common principle in IMs -the binding of an antibody...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800411402494
更新日期:2011-07-01 00:00:00
abstract::Preterm birth (PTB; spontaneous delivery prior to 37 weeks gestation) affects one out of eight infants born in the United States and is the most common cause of neonatal morbidity and mortality. Although the pathogenesis of PTB is multifactorial, a growing body of literature supports the hypothesis that one cause of P...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800409344620
更新日期:2010-04-01 00:00:00