Abstract：
PURPOSE:Activity restriction (AR), one of the most common interventions used in high-risk pregnancies, may exacerbate loss of bone mass. The purpose of this study was to determine changes over time in bone resorption in hospitalized AR women during late pregnancy. METHODS:This was a short-term prospective study conducted in two tertiary-care obstetric hospitals. We measured urinary deoxypyridinoline (Dpd) excretion, a marker of bone resorption, once per week in a convenience sample of 14 hospitalized AR women in the third trimester and compared values at 28-31 and 34-36 weeks' gestation to those of 11 ambulatory control women. Both groups completed a bone-loading questionnaire, 3-day food intake record, and pedometer step counts at the same gestational age. RESULTS:Urinary Dpd excretion increased from Days 1-7 (2.60 ± 0.32 nmol/mmol creatinine) to Days 22-28 (5.36 ± 0.83 nmol/mmol creatinine; p ≤ .05). Dpd excretion was higher in AR women (4.51 ± 0.31 nmol/mmol creatinine) than ambulatory women (2.72 ± 0.39 nmol/mmol creatinine) at 34-36 weeks' gestation (p ≤ .05). Energy intake between ambulatory and AR women was not different (p ≥ .05). All women met the daily requirements for calcium and vitamin D intake during pregnancy. Average daily pedometer steps for the AR women were significantly less compared to controls (1,329 ± 936 and 8,024 ± 1,890 steps/day, respectively; p ≤ .05). CONCLUSIONS:AR leads to increased bone resorption in hospitalized pregnant women, which may impact future risk of developing osteopenia and osteoporosis.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Vanderspank D,Bernier SM,Sopper MM,Watson P,Mottola MFdoi
10.1177/1099800412463120subject
Has Abstractpub_date
2014-01-01 00:00:00pages
7-15issue
1eissn
1099-8004issn
1552-4175pii
1099800412463120journal_volume
16pub_type
杂志文章abstract：:Variations in sex hormones influence bone health in men. Aging in men is associated with a decrease in testosterone (T) levels. We examined the relationship between T levels and changes in bone health status as measured by quantitative ultrasound (QUS) at the phalanges and the os calcis and by peripheral bone mineral ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414532710
更新日期：2015-03-01 00:00:00
abstract：:Scientists and clinicians frequently use immunological methods (IMs) to investigate complex biological phenomena. Commonly used IMs include immunocytochemistry (IC), enzyme-linked immunosorbent assays (ELISA) and flow cytometry. Each of these methodologies exploits a common principle in IMs -the binding of an antibody...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800411402494
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:Eating disorders are a significant cause of morbidity and mortality. The etiology and maintenance of eating-disorder symptoms are not well understood. Evidence suggests that there may be gustatory alterations in patients with eating disorders. OBJECTIVE:This article systematically reviews research assessing...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800419872824
更新日期：2020-01-01 00:00:00
abstract：:Cytokines are small signaling proteins released from a variety of cells that influence virtually every aspect of growth and development and every host response to infection, injury, and inflammation. Because of their widespread and potent effects across the life span, cytokines without a doubt influence nursing resear...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/109980040000200105
更新日期：2000-07-01 00:00:00
abstract：OBJECTIVE:The sacral skin of bedridden older patients often develops a dysbiotic condition. To clarify whether the condition changes or is sustained over time, we analyzed the skin microbiome and the skin physiological functions of the sacral skin in patients who completed our 2017 study. METHODS:In 2019, we collected...
journal_title：Biological research for nursing
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abstract：PURPOSE:Sleep deficit affects neurobehavioral functioning, reduces attention and cognitive function, and negatively impacts occupational safety. This study investigated selective attention levels of nursing staff on different shifts. METHODS:Using a prospective, randomized parallel group study, selective attention was...
journal_title：Biological research for nursing
pub_type： 杂志文章,随机对照试验
doi：10.1177/1099800412445907
更新日期：2013-10-01 00:00:00
abstract：OBJECTIVE:To investigate the prevalence and patterns of and factors associated with hyperphagic behavior in Taiwanese patients with dementia living at home. METHODS:A cross-sectional and correlational design was used. A total of 104 patients with dementia and their primary caregivers were recruited from the geriatric,...
journal_title：Biological research for nursing
pub_type： 杂志文章
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abstract：:Survivors of aneurysmal subarachnoid hemorrhage (aSAH) often experience unfavorable functional outcomes that result in a reduced ability to independently perform activities of daily living. The apolipoprotein E gene ( APOE) encodes for a protein known to facilitate lipid transport and aid in neuronal repair within the...
journal_title：Biological research for nursing
pub_type： 杂志文章
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abstract：OBJECTIVE:We examined genomic variation potentially associated with the cortisol stress response in children having a painful medical procedure. DESIGN:Children 4-10 years old having a peripheral intravenous line inserted provided saliva samples for evaluation of the cortisol response as a biological measure of distre...
journal_title：Biological research for nursing
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更新日期：2019-03-01 00:00:00
abstract：:Self-management programs that include cognitive behavioral strategies have been shown to improve gastrointestinal (GI) symptoms, psychological distress, and quality of life (QoL) in persons with irritable bowel syndrome (IBS). However, less is known about the physiological impact of such a change. As part of a randomi...
journal_title：Biological research for nursing
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更新日期：2013-01-01 00:00:00
abstract：:The purposes of this quasi-experimental pilot study were to determine adherence to a 12-week group-based moderate-intensity walking program for sedentary adult outpatients with serious and persistent mental illness and to examine change from baseline to after the walking program in health status (mental and physical h...
journal_title：Biological research for nursing
pub_type： 临床试验,杂志文章
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更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:Roux-en-Y gastric bypass (RYGB) is considered the gold standard for gastric bypass, displaying better results for metabolic disorders than other surgical procedures over the long term. The aim of this study was to determine the effects of bariatric surgery, in particular the RYGB technique, on metabolic synd...
journal_title：Biological research for nursing
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更新日期：2017-03-01 00:00:00
abstract：:Military personnel experience posttraumatic stress disorder (PTSD), which is associated with differential DNA methylation across the whole genome. However, the relationship between these DNA methylation patterns and clinically relevant increases in PTSD severity is not yet clearly understood. The purpose of this study...
journal_title：Biological research for nursing
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更新日期：2018-05-01 00:00:00
abstract：:Depression is the leading cause of disability worldwide, and its prevalence is 2 times higher in women than in men. There is, however, a lack of data on sex-specific pathophysiology of this disorder. The purpose of this systematic review is to identify the biological sex differences found in major depressive disorder ...
journal_title：Biological research for nursing
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journal_title：Biological research for nursing
pub_type： 杂志文章,评审
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更新日期：2018-03-01 00:00:00
abstract：OBJECTIVE:Although the roles of testosterone and cortisol in various health problems have been extensively investigated, little is known about their associations with health outcomes in mothers and their very-low-birthweight (VLBW) infants when maternal testosterone and cortisol are examined together during the postpar...
journal_title：Biological research for nursing
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abstract：:Research that uses a psychoneuroimmunology (PNI) framework seeks to determine whether valid associations exist among stress, immune function, and health. These associations are difficult to conclusively determine due to the fact that PNI research is fraught with methodological difficulties. These difficulties arise fr...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/10900402003004002
更新日期：2002-04-01 00:00:00
abstract：:The psychophysiological phenomenon of pain is of tremendous concern to nurses because of its potential to adversely affect the mental, emotional, and physical health of patients. Increasingly appreciated is the ability of pain to influence immune variables including enumerative and functional measures of leukocyte sub...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
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更新日期：2006-04-01 00:00:00
abstract：:The current study was performed to evaluate the antinociceptive and antiedematogenic properties of andrographolide isolated from the leaves of Andrographis paniculata using two animal models. Antinociceptive activity was evaluated using the acetic acid- induced writhing and the hot-plate tests, while antiedematogenic ...
journal_title：Biological research for nursing
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更新日期：2010-01-01 00:00:00
abstract：:Abdominal pain is an important symptom in irritable bowel syndrome (IBS), but patients report typical pain intensities ranging from mild to very severe. In a sample of women, the authors sought to determine whether measures of systemic autonomic activity are related to self-reported pain intensity and the occurrence o...
journal_title：Biological research for nursing
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更新日期：2000-10-01 00:00:00
abstract：:The purpose of this study was to describe the sleep patterns and fatigue of both mothers and fathers before and after childbirth. The authors used wrist actigraphy and questionnaires to estimate sleep and fatigue in 72 couples during their last month of pregnancy and 1st month postpartum. Both parents experienced more...
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journal_title：Biological research for nursing
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更新日期：2013-04-01 00:00:00
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更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Drug addiction is a multifactorial disorder. Researchers have posited that an individual's inherited behavioral propensity or temperament contributes to the disorder by shaping a personality strongly linked with the risk of drug abuse. Further, they hypothesize that the polymorphism of dopamine D2 receptor i...
journal_title：Biological research for nursing
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更新日期：2012-04-01 00:00:00
abstract：:People with schizophrenia have a higher prevalence of obesity than the general population. Many people with this illness struggle with weight gain, due, in part, to medications and other factors that act as obstacles to exercise and healthy eating. Several studies have shown the benefits of behavioral weight loss prog...
journal_title：Biological research for nursing
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更新日期：2011-10-01 00:00:00
abstract：:Despite high efficacy rates, significant costs and logistical challenges associated with procuring stool from healthy donors for fecal microbiota transplantation (FMT) have presented barriers to broader institutional adoption and limited the availability of this life-saving treatment. Published outcomes for donor scre...
journal_title：Biological research for nursing
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更新日期：2021-01-01 00:00:00
abstract：:Benefits of daily physical activity are well known, but there are limited data to describe physical activity in heart failure patients who receive cardiac resynchronization therapy devices. The purpose of this pilot study was to evaluate changes in physical activity (PA) levels before and 3 months after Cardiac Resync...
journal_title：Biological research for nursing
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更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:Insulin resistance plays a determinant role in the development of metabolic syndrome in adolescents. The objective of the present study was to determine the influence of factors commonly associated with insulin resistance in a sample of adolescents. METHODS:This cross-sectional study included 976 adolescent...
journal_title：Biological research for nursing
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