Comparison of autonomic nervous system indices based on abdominal pain reports in women with irritable bowel syndrome.

Abstract:

:Abdominal pain is an important symptom in irritable bowel syndrome (IBS), but patients report typical pain intensities ranging from mild to very severe. In a sample of women, the authors sought to determine whether measures of systemic autonomic activity are related to self-reported pain intensity and the occurrence of pain in the postprandial period. One hundred and six women with IBS and 41 controls completed bowel symptom and psychological distress questionnaires and wore 24-h Holter electrocardiogram monitors to estimate global heart rate variability measures of parasympathetic activity and sympathetic nervous system/parasympathetic nervous system balance. About one-third of the IBS sample reported severe or very severe abdominal pain (n = 34/106), and about one-half of the IBS sample reported postprandial pain (n = 52/106). Even after statistically controlling for age, body mass index, and psychological distress, vagal heart rate variability measures were markedly lower in women reporting high pain (P < 0.01) and markedly higher in women reporting postprandial pain (P < 0.02). The vagal component of heart rate variability appears to be reduced in women with severe abdominal pain, especially in those whose pain is not postprandial.

journal_name

Biol Res Nurs

authors

Burr RL,Heitkemper M,Jarrett M,Cain KC

doi

10.1177/109980040000200203

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

97-106

issue

2

eissn

1099-8004

issn

1552-4175

journal_volume

2

pub_type

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