Abstract:
:Self-management programs that include cognitive behavioral strategies have been shown to improve gastrointestinal (GI) symptoms, psychological distress, and quality of life (QoL) in persons with irritable bowel syndrome (IBS). However, less is known about the physiological impact of such a change. As part of a randomized controlled trial using a comprehensive self-management (CSM) intervention (n = 126) compared to usual care (UC; n = 62), cortisol levels were measured in 4 weekly first morning urine samples at baseline and at 3-, 6-, and 12-month follow-up. In addition, diary (28 days) ratings of stress were recorded at baseline, 3, 6, and 12 months. The omnibus test of all three outcome times showed no differences in urine cortisol levels between the CSM and UC groups (p = .400); however, at 3 months the CSM group had significantly higher cortisol levels than the UC group (p = .012). The CSM group reported lower daily stress levels (p = .046 from the omnibus test of all 3 time points) than the UC group, with the effect getting stronger over time. Despite marked improvements in reported stress and previously reported GI and psychological distress symptoms at later follow-ups, the CSM program did not reduce urine cortisol levels in adults with IBS. These results suggest that the first-void urine cortisol levels are not reflective of self-reported daily stress in this patient population.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Deechakawan W,Cain KC,Jarrett ME,Burr RL,Heitkemper MMdoi
10.1177/1099800411414047subject
Has Abstractpub_date
2013-01-01 00:00:00pages
26-36issue
1eissn
1099-8004issn
1552-4175pii
1099800411414047journal_volume
15pub_type
杂志文章abstract:PURPOSE:In recent years, researchers have noted an "obesity paradox," where individuals with obesity survive sepsis at higher rates than their nonobese counterparts. This systematic review summarizes the literature on studies examining the association between obesity and 1-year mortality among patients admitted with se...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800419876070
更新日期:2020-01-01 00:00:00
abstract::This article explores ethical concerns and emerging dilemmas associated with the proliferation of information resulting from the extraordinary advances in molecular genetics. It provides an overview of the ethical and legal challenges associated with predictive testing for inherited disease currently being addressed i...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/109980040100300104
更新日期:2001-07-01 00:00:00
abstract::Maternal posturing, in which a pregnant or laboring woman assumes specific postures with the intention of altering the position and/or presentation of the fetus within the uterus, is a safe alternative to operative procedures recommended in cases of fetal malpositions and malpresentations. Clinicians and researchers a...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800404268318
更新日期:2004-10-01 00:00:00
abstract::Delirium is a serious complication of acute illness. Little is known, however, regarding the neurobiology of delirium, largely due to challenges in studying the complex inpatient population. Neuroimaging is one noninvasive method that can be used to study structural and functional brain abnormalities associated with d...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800419849489
更新日期:2019-07-01 00:00:00
abstract::Postpartum depression (PPD) is a serious mood disorder that may carry life-long consequences for a woman and her family. Multiple risk factors for PPD have been identified, including psychosocial, situational, and biological stimuli, several of which are experienced by most, if not all, postpartum women. Given the com...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800410362112
更新日期:2010-07-01 00:00:00
abstract::Preterm birth (PTB; spontaneous delivery prior to 37 weeks gestation) affects one out of eight infants born in the United States and is the most common cause of neonatal morbidity and mortality. Although the pathogenesis of PTB is multifactorial, a growing body of literature supports the hypothesis that one cause of P...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
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更新日期:2010-04-01 00:00:00
abstract::For precision health care to be successful, an in-depth understanding of the biological mechanisms for symptom development and severity is essential. Omics-based research approaches facilitate identification of the biological underpinnings of symptoms. We reviewed literature for omics-based approaches and exemplar sym...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
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更新日期:2018-03-01 00:00:00
abstract::Multiple chemical sensitivity (MCS) is a chronic condition prevalent in women; the symptoms are reproducible with repeated low-level chemical exposure. Evidence gathered through clinical observations suggests that women with MCS may be at risk for autonomic nervous system dysfunction as evidenced by abnormal heart rat...
journal_title:Biological research for nursing
pub_type: 杂志文章
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更新日期:2009-01-01 00:00:00
abstract::Scientists and clinicians frequently use immunological methods (IMs) to investigate complex biological phenomena. Commonly used IMs include immunocytochemistry (IC), enzyme-linked immunosorbent assays (ELISA) and flow cytometry. Each of these methodologies exploits a common principle in IMs -the binding of an antibody...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800411402494
更新日期:2011-07-01 00:00:00
abstract::Interpretation of changes in health and health care utilization patterns across the life span depends on an understanding of the effects of age, period, and cohort. The purpose of this article is to illustrate differences among three generations of women in demographic factors, health risk factors, and health status i...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800410373804
更新日期:2010-10-01 00:00:00
abstract::Military personnel experience posttraumatic stress disorder (PTSD), which is associated with differential DNA methylation across the whole genome. However, the relationship between these DNA methylation patterns and clinically relevant increases in PTSD severity is not yet clearly understood. The purpose of this study...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800418758951
更新日期:2018-05-01 00:00:00
abstract::The focus on a cure for childhood leukemia over the last three decades has resulted in survival rates of more than 80%. However, efforts to manage leukemia-treatment symptoms have not kept pace with new therapies. Symptom toxicity during treatment can result in complications, treatment delays, and therapy dose reducti...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800418772907
更新日期:2018-07-01 00:00:00
abstract::The purpose of this study was to examine whether the hepatitis B seroconversion rates in a small sample of subjects reflected that of the published rates, regardless of HIV status, after a hepatitis B vaccination series was completed while following strict vaccine protocols. The study, which had a nonexperimental, cor...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800414524619
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To investigate associations between components of cumulative risk (CR) and physiological stress responses in African American adolescents and evaluate emotion regulation as a mediator and sex as a moderator of these associations. METHODS:Cortisol and salivary alpha amylase (sAA) were collected in adolescents...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417702742
更新日期:2017-07-01 00:00:00
abstract::Cytokines such as angiogenin (ANG) and interleukin (IL-8) have been shown to be related to depressive symptoms and inflammatory diseases like coronary heart disease. They may thus be used as stress biomarkers to identify and prevent health problems. To investigate the relationship between cytokines and nurses' job-rel...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800408323219
更新日期:2008-10-01 00:00:00
abstract::Abdominal pain is an important symptom in irritable bowel syndrome (IBS), but patients report typical pain intensities ranging from mild to very severe. In a sample of women, the authors sought to determine whether measures of systemic autonomic activity are related to self-reported pain intensity and the occurrence o...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/109980040000200203
更新日期:2000-10-01 00:00:00
abstract::Sickness behavior is a cluster of symptoms that occur as a response to an infection and alterations in the inflammatory response. Under normal circumstances, sickness behavior is fully reversible once the pathogen has been cleared. Aging and chronic illness such as heart failure are associated with enhanced inflammato...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800412466170
更新日期:2014-01-01 00:00:00
abstract::People with schizophrenia have a higher prevalence of obesity than the general population. Many people with this illness struggle with weight gain, due, in part, to medications and other factors that act as obstacles to exercise and healthy eating. Several studies have shown the benefits of behavioral weight loss prog...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800410393272
更新日期:2011-10-01 00:00:00
abstract::Bidirectional communication between the immune system and the brain and the implications of this communication are emerging concepts in pain research. Although representing a small portion of the disc degeneration syndromes, lumbar herniated discs can cause significant symptoms that may persist even after surgical int...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800404272221
更新日期:2005-01-01 00:00:00
abstract::Variations in sex hormones influence bone health in men. Aging in men is associated with a decrease in testosterone (T) levels. We examined the relationship between T levels and changes in bone health status as measured by quantitative ultrasound (QUS) at the phalanges and the os calcis and by peripheral bone mineral ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800414532710
更新日期:2015-03-01 00:00:00
abstract::Food intake and, subsequently, body weight are influenced by endogenous opioids acting in the central nervous system. Agonists for the opioid receptor increase food intake, whereas antagonists reduce food intake. Body weight, however, is the result of food consumed and energy expended. Although much has been reported ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800406298774
更新日期:2007-04-01 00:00:00
abstract::The primary purpose of this exploratory study was to compare percentages of natural killer (NK) cells and activated NK and T cells, and both cytotoxic and in vitro cytokine production activity in women with and without symptomatic irritable bowel syndrome (IBS). A secondary purpose was to examine the relationships of ...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800402004001005
更新日期:2002-07-01 00:00:00
abstract::Age-related changes in skeletal muscle, in combination with bed rest, may result in a poorer rehabilitation potential for an elderly patient. The purpose of this study was to determine the effects of non-weight bearing (hind limb unweighting [HU]) on the soleus and extensor digitorum longus (EDL) in older rats. Two no...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800403260693
更新日期:2004-01-01 00:00:00
abstract::The ability to maintain balance is often taken for granted, yet it is the foundation for mobility and overall functional independence throughout the life span. The purpose of this article is to define balance, review the components of balance, and describe common instruments used to measure balance. Clinical screening...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/109980040000100408
更新日期:2000-04-01 00:00:00
abstract::The purposes of this quasi-experimental pilot study were to determine adherence to a 12-week group-based moderate-intensity walking program for sedentary adult outpatients with serious and persistent mental illness and to examine change from baseline to after the walking program in health status (mental and physical h...
journal_title:Biological research for nursing
pub_type: 临床试验,杂志文章
doi:10.1177/1099800405278116
更新日期:2005-10-01 00:00:00
abstract::Sleep disturbance is a common and disturbing symptom in military personnel, with many individuals progressing to the development of insomnia, which is characterized by increased arousals, wakefulness after sleep onset, and distorted sleep architecture. The molecular mechanisms underlying insomnia remain elusive, limit...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800415575343
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Roux-en-Y gastric bypass (RYGB) is considered the gold standard for gastric bypass, displaying better results for metabolic disorders than other surgical procedures over the long term. The aim of this study was to determine the effects of bariatric surgery, in particular the RYGB technique, on metabolic synd...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800416675406
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Drug addiction is a multifactorial disorder. Researchers have posited that an individual's inherited behavioral propensity or temperament contributes to the disorder by shaping a personality strongly linked with the risk of drug abuse. Further, they hypothesize that the polymorphism of dopamine D2 receptor i...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800411405030
更新日期:2012-04-01 00:00:00
abstract::Listening to soothing music has been used as a complementary therapy to improve sleep quality. However, there is no empirical evidence for the effects of music videos (MVs) on sleep quality in adults with insomnia as assessed by polysomnography (PSG). In this randomized crossover controlled trial, we compared the effe...
journal_title:Biological research for nursing
pub_type: 杂志文章,随机对照试验
doi:10.1177/1099800414549237
更新日期:2015-05-01 00:00:00
abstract::Depression increases the risk of adverse cardiac events. Cardiovascular reactivity is defined as the pattern of cardiovascular responses to mental stress. An altered pattern of cardiovascular reactivity is an indicator of subsequent cardiovascular disease. Because depression and adverse cardiac events may have a dose-...
journal_title:Biological research for nursing
pub_type: 杂志文章
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更新日期:2016-03-01 00:00:00