Abstract：
:Approximately half of the Canadian adults have sedentary lifestyles that increase their risk of developing cardiovascular disease (CVD). Women are 10 times more likely to die from CVD than from any other disease. Their risk almost doubles with the onset of menopause, which may result in increased body iron burden and oxidative stress in sedentary women. Body iron burden may catalyze the production of cytotoxic oxygen species in vivo. We hypothesized that postmenopausal women who engage in moderate forms of aerobic exercise for at least 30 min three or more times per week would have significantly (i) lower levels of body iron burden, (ii) increased glutathione peroxidase (GPx) activity, and (iii) decreased oxidative stress in comparison to sedentary controls. An age-matched, case-control study was employed to examine the effects of active (N = 25) versus sedentary (N = 25) lifestyles in women aged 55-65 years on measures of body iron burden as quantified by total serum iron, transferrin saturation, and serum ferritin levels; GPx activity; and oxidative stress as quantified by 4-hydroxynonenal, malondialdehyde, and hexanal. Measures of body iron burden were significantly elevated in sedentary women in comparison to active women (p < .001). Red cell GPx activity was higher in active women compared to sedentary women (p < .001). Measures of oxidative stress were significantly higher in sedentary versus active women (p < .001). These findings suggest that aerobic forms of exercise may mitigate the risk of developing CVD in postmenopausal women by improving antioxidant capacity and decreasing body iron burden.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Bartfay W,Bartfay Edoi
10.1177/1099800413501717subject
Has Abstractpub_date
2014-01-01 00:00:00pages
38-45issue
1eissn
1099-8004issn
1552-4175pii
1099800413501717journal_volume
16pub_type
杂志文章abstract：:Fatigue is the most frequently reported symptom by cancer patients. Many of these patients perceive fatigue as the most distressing symptom associated with their illness because it imposes limitations on their physical activity level. Skeletal muscle wasting, which occurs as part of cancer cachexia, is one of the mech...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/109980040100200304
更新日期：2001-01-01 00:00:00
abstract：:The American Academy of Pediatrics recently removed nicotine from the list of drugs contraindicated during breastfeeding. The objective of this study was to evaluate the feasibility of determining the effect of a smoking hygiene intervention on infants of breastfeeding mothers who smoke cigarettes. An experimental des...
journal_title：Biological research for nursing
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1177/1099800406290643
更新日期：2006-10-01 00:00:00
abstract：:The purpose of this study was to evaluate for differences in variations in pro- and anti-inflammatory cytokine genes between participants who were classified as having low and high levels of morning and evening fatigue and to evaluate for differences in phenotypic characteristics between these two groups. In a sample ...
journal_title：Biological research for nursing
pub_type： 杂志文章
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journal_title：Biological research for nursing
pub_type： 杂志文章
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abstract：:Stress during pregnancy has been associated with a number of adverse outcomes. This study compared and correlated neuroendocrine parameters in women (n=8) who self-reported battering during their pregnancy to those in women who did not (n=8). Women who identified themselves as having a violent relationship with an int...
journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:The objectives of this study were to determine the change in gene expression between two time points following stroke and to identify biomarkers of stroke recovery through gene expression profiling and pathway analysis. METHODS:Peripheral blood was collected from 34 ischemic stroke patients (confirmed by ma...
journal_title：Biological research for nursing
pub_type： 杂志文章
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abstract：AIM:The purpose of this paper is to review the techniques and implications of laser capture microdissection (LCM) to isolate tissue and DNA of interest using breast biopsy tissue as an example. BACKGROUND:Tissues are a heterogeneous mix of different cell types, and molecular alterations are often specific to a single ...
journal_title：Biological research for nursing
pub_type： 杂志文章
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pub_type： 杂志文章,随机对照试验
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更新日期：2016-05-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2010-10-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2000-10-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章,评审
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更新日期：2009-04-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章
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journal_title：Biological research for nursing
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更新日期：2014-01-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章,评审
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journal_title：Biological research for nursing
pub_type： 杂志文章
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journal_title：Biological research for nursing
pub_type： 杂志文章,评审
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更新日期：2014-04-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章,评审
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journal_title：Biological research for nursing
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journal_title：Biological research for nursing
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journal_title：Biological research for nursing
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journal_title：Biological research for nursing
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journal_title：Biological research for nursing
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