Abstract：
PURPOSE:In recent years, researchers have noted an "obesity paradox," where individuals with obesity survive sepsis at higher rates than their nonobese counterparts. This systematic review summarizes the literature on studies examining the association between obesity and 1-year mortality among patients admitted with sepsis, severe sepsis, or septic shock. MATERIALS AND METHODS:Using a comprehensive search strategy, a systematic review was conducted to identify studies examining the association of obesity and sepsis mortality. PubMed, Cumulative Index of Nursing and Allied Health Literature, and Elton B. Stephens Company host databases were searched for the terms sepsis, obesity, mortality, and adult. RESULTS:The initial search identified 189 studies, 9 of which met inclusion criteria. Of these, four provided evidence that obese or very obese patients with sepsis have lower mortality than nonobese patients. Methodologic differences in the remaining five studies, which reported conflicting results, limit generalizability. CONCLUSION:This systematic review on the association of obesity and sepsis mortality found three studies that demonstrated lower sepsis mortality among obese patients in the first 30 days and one showing that this protective effect extends up to 1 year. Given the increased number of patients surviving sepsis, it is important to consider long-term mortality and further describe the variables associated with increased survival.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Robinson J,Swift-Scanlan T,Salyer Jdoi
10.1177/1099800419876070subject
Has Abstractpub_date
2020-01-01 00:00:00pages
103-113issue
1eissn
1099-8004issn
1552-4175journal_volume
22pub_type
杂志文章abstract：:Survivors of aneurysmal subarachnoid hemorrhage (aSAH) often experience unfavorable functional outcomes that result in a reduced ability to independently perform activities of daily living. The apolipoprotein E gene ( APOE) encodes for a protein known to facilitate lipid transport and aid in neuronal repair within the...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800417746504
更新日期：2018-03-01 00:00:00
abstract：:To examine the effects of exercise and vitamin E supplementation on oxidative stress in older adults, 59 participants, age 76.3 +/- 4.2 years, were randomly assigned to 1 of 4 groups: an exercise group taking placebos (EGP) or vitamin E (EGE) or a sedentary group taking placebos (SGP) or vitamin E (SGE). Measures incl...
journal_title：Biological research for nursing
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1177/1099800403005001005
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:Leptin and adiponectin, two adipokines involved in glucose and lipid metabolism, have been linked to regulation of growth in early infancy, energy balance, and metabolic disorders in childhood. The aim of this study was to determine if concentrations of leptin and adiponectin could be measured reliably in in...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800420973366
更新日期：2020-11-28 00:00:00
abstract：:The purpose of this study was to evaluate for differences in variations in pro- and anti-inflammatory cytokine genes between participants who were classified as having low and high levels of morning and evening fatigue and to evaluate for differences in phenotypic characteristics between these two groups. In a sample ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414534313
更新日期：2015-03-01 00:00:00
abstract：:The ability to maintain balance is often taken for granted, yet it is the foundation for mobility and overall functional independence throughout the life span. The purpose of this article is to define balance, review the components of balance, and describe common instruments used to measure balance. Clinical screening...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/109980040000100408
更新日期：2000-04-01 00:00:00
abstract：AIM:The purpose of this paper is to review the techniques and implications of laser capture microdissection (LCM) to isolate tissue and DNA of interest using breast biopsy tissue as an example. BACKGROUND:Tissues are a heterogeneous mix of different cell types, and molecular alterations are often specific to a single ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800411402054
更新日期：2011-07-01 00:00:00
abstract：:Night-shift workers are prone to sleep deprivation, misalignment of circadian rhythms, and subsequent sleepiness and sleep-related performance deficits. The purpose of this narrative systematic review is to critically review and synthesize the scientific literature regarding improvements in sleepiness and sleep-relate...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800413476571
更新日期：2014-04-01 00:00:00
abstract：:Benefits of daily physical activity are well known, but there are limited data to describe physical activity in heart failure patients who receive cardiac resynchronization therapy devices. The purpose of this pilot study was to evaluate changes in physical activity (PA) levels before and 3 months after Cardiac Resync...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800413481619
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVES:To explore whether newborns born via Cesarean section have a weaker intraoral vacuum compared with those born vaginally and to determine whether a weaker intraoral vacuum is related to a delayed onset of lactation. METHODS:For this prospective cohort study, 71 mother-infant dyads were enrolled and divided i...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416636687
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Persistent organic pollutants (POPs), dispersed in all environmental compartments, are associated with increased adipogenesis and body weight. These lipophilic toxicants bioaccumulate in the human body and get transferred from mothers to their offspring via the placental circulation and breast milk. The curr...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800420909151
更新日期：2020-04-01 00:00:00
abstract：RESULTS:hs-CRP correlated significantly with SLEDAI-2K (p = .036), SDI (p = .00), anti-dsDNA titers (p = .034), diabetes (p = .005), and obesity (p = .027). hs-CRP and Hcy correlated with triglyceride (TG) levels (p = .032 and p < .001, respectively), TG/high-density lipoprotein cholesterol index (p = .020 and p = .001...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800419889192
更新日期：2020-04-01 00:00:00
abstract：:Postpartum depression (PPD) is a serious mood disorder that may carry life-long consequences for a woman and her family. Multiple risk factors for PPD have been identified, including psychosocial, situational, and biological stimuli, several of which are experienced by most, if not all, postpartum women. Given the com...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800410362112
更新日期：2010-07-01 00:00:00
abstract：INTRODUCTION:Diabetes is a serious health problem affecting approximately 29.1 million individuals in the United States. Another 86 million have prediabetes. The development and implementation of lifestyle modifications such as physical activity for these persons are among the most effective methods for prevention and ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800418767572
更新日期：2018-07-01 00:00:00
abstract：:Cytokines such as angiogenin (ANG) and interleukin (IL-8) have been shown to be related to depressive symptoms and inflammatory diseases like coronary heart disease. They may thus be used as stress biomarkers to identify and prevent health problems. To investigate the relationship between cytokines and nurses' job-rel...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800408323219
更新日期：2008-10-01 00:00:00
abstract：:This article explores ethical concerns and emerging dilemmas associated with the proliferation of information resulting from the extraordinary advances in molecular genetics. It provides an overview of the ethical and legal challenges associated with predictive testing for inherited disease currently being addressed i...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/109980040100300104
更新日期：2001-07-01 00:00:00
abstract：:Shift work schedules, intensive physical exercise late in the day, psychological stress, or a busy lifestyle might induce disorders of the circadian structure, which can affect health on both the physiological and neurobehavioral levels. Rest-activity rhythm is strongly connected with an organism's circadian structure...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800411416224
更新日期：2013-01-01 00:00:00
abstract：:The purpose of this study was to examine whether the hepatitis B seroconversion rates in a small sample of subjects reflected that of the published rates, regardless of HIV status, after a hepatitis B vaccination series was completed while following strict vaccine protocols. The study, which had a nonexperimental, cor...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414524619
更新日期：2015-01-01 00:00:00
abstract：:African American (AA) women are nearly twice as likely as non-Hispanic White (NHW) women to develop atherosclerosis associated with cardiovascular disease. Compelling evidence demonstrates that stress-related biomarkers, such as heat shock protein-70 (HSP70), are associated with increased atherosclerosis risk. Yet lit...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800413491422
更新日期：2014-07-01 00:00:00
abstract：:For precision health care to be successful, an in-depth understanding of the biological mechanisms for symptom development and severity is essential. Omics-based research approaches facilitate identification of the biological underpinnings of symptoms. We reviewed literature for omics-based approaches and exemplar sym...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800417751069
更新日期：2018-03-01 00:00:00
abstract：:The psychophysiological phenomenon of pain is of tremendous concern to nurses because of its potential to adversely affect the mental, emotional, and physical health of patients. Increasingly appreciated is the ability of pain to influence immune variables including enumerative and functional measures of leukocyte sub...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800405286071
更新日期：2006-04-01 00:00:00
abstract：:The integration of molecular genetics approaches into the study of complex health phenomena is an increasingly important and available strategy for researchers across the health science disciplines. Pain sensation and response to painful stimuli are examples of complex health phenomena that are particularly amenable t...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800406289909
更新日期：2006-07-01 00:00:00
abstract：:The effects of a 12-week low-intensity exercise conditioning program (walking) on blood pressure (BP), heart rate (HR), rate-pressure product (RPP), and cardiac autonomic function were measured in 40 sedentary women with hypertension. Women were assigned to either an exercise group (n = 20) or a control group (n = 20)...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800412461562
更新日期：2013-10-01 00:00:00
abstract：:The current study was performed to evaluate the antinociceptive and antiedematogenic properties of andrographolide isolated from the leaves of Andrographis paniculata using two animal models. Antinociceptive activity was evaluated using the acetic acid- induced writhing and the hot-plate tests, while antiedematogenic ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800409343311
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Application of a thermal stimulus is a common procedure used to promote venodilation for peripheral intravenous cannulation (PIVC); however, the effects of thermal stimulation on the duration of venodilation and skin temperature of the forearm are unclear. AIM:To investigate the duration of venodilation ind...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416651145
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Our program of research focuses on thermal and circulatory stability in extremely premature infants. In prior studies, we found that infants have long periods of time in which foot temperature (FT) is higher than central temperature. We thus wanted to determine whether blood flow in the foot is increased whe...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416656914
更新日期：2017-01-01 00:00:00
abstract：:The prevalence of vascular dementia continues to increase with no cure. Thus, it is important identify the aggravating factors of vascular dementia to delay disease progression in patients. Obesity is a well-known risk factor for vascular dementia and causes mild cognitive impairment. In the present study, we evaluate...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800420951633
更新日期：2020-08-26 00:00:00
abstract：:Paclitaxel (PAC) treatment is associated with persistent, debilitating neuropathic pain that affects the hands and feet. Female sex and biological stress responsivity are risk factors for persistent pain, but it is unclear whether these important biologically based factors confer risk for PAC-induced neuropathic pain....
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800415609418
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVES:The objectives of this study were to determine the change in gene expression between two time points following stroke and to identify biomarkers of stroke recovery through gene expression profiling and pathway analysis. METHODS:Peripheral blood was collected from 34 ischemic stroke patients (confirmed by ma...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414546492
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Insulin resistance plays a determinant role in the development of metabolic syndrome in adolescents. The objective of the present study was to determine the influence of factors commonly associated with insulin resistance in a sample of adolescents. METHODS:This cross-sectional study included 976 adolescent...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416648207
更新日期：2016-10-01 00:00:00
abstract：:Sleep disturbance is a common and disturbing symptom in military personnel, with many individuals progressing to the development of insomnia, which is characterized by increased arousals, wakefulness after sleep onset, and distorted sleep architecture. The molecular mechanisms underlying insomnia remain elusive, limit...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800415575343
更新日期：2015-07-01 00:00:00
