Abstract：
:Postpartum depression (PPD) affects at least 10% to 15% of postpartum women, including more than 600,000 American mothers in 2003 alone. Dramatic changes in the hypothalamic-pituitary-adrenal (HPA) system in the transition from pregnancy to postpartum coupled with research on the psychobiology of depression provided the foundation for this study. The purpose of this study was to compare the reactivity and regulation of the HPA axis components, adrenocorticotropic hormone (ACTH) and cortisol, in depressed and nondepressed postpartum women. A comparative, longitudinal study design was used with 22 normal, healthy, nondepressed pregnant women. Physiologic and postpartum depression data were collected at 6 and 12 weeks postpartum at a university clinical research center. Maximal treadmill exercise stimulated plasma ACTH and serum cortisol levels which were measured before, during, and after 20 min of exercise. Postpartum depression was measured with the Postpartum Depression Screening Scale. Lag within-subject ACTH levels predicting cortisol regression slopes were significantly different between the depressed and nondepressed groups at both 6 and 12 weeks. The depressed group showed no relationship between their ACTH and cortisol levels, with higher ACTH and lower cortisol levels when compared with the nondepressed group. The expected regulated relationship with cortisol levels rising in response to rising ACTH levels was found in the non-depressed group. These findings indicate that the HPA axis was dysregulated in the depressed group, but regulated in the nondepressed group at 6 and 12 weeks postpartum. This pattern of higher ACTH levels to stimulate less cortisol is similar to patterns found in women with early life stresses.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Jolley SN,Elmore S,Barnard KE,Carr DBdoi
10.1177/1099800406294598subject
Has Abstractpub_date
2007-01-01 00:00:00pages
210-22issue
3eissn
1099-8004issn
1552-4175pii
8/3/210journal_volume
8pub_type
杂志文章abstract：:The theoretical constructs of allostasis and allostatic load (AL) have contributed to our understanding of how constantly changing social and environmental factors impact physiological functioning and shape health and aging disparities, particularly along socioeconomic, gendered, racial, and ethnic lines. AL represent...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800412455688
更新日期：2012-10-01 00:00:00
abstract：:Interpretation of changes in health and health care utilization patterns across the life span depends on an understanding of the effects of age, period, and cohort. The purpose of this article is to illustrate differences among three generations of women in demographic factors, health risk factors, and health status i...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800410373804
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abstract：:The integration of molecular genetics approaches into the study of complex health phenomena is an increasingly important and available strategy for researchers across the health science disciplines. Pain sensation and response to painful stimuli are examples of complex health phenomena that are particularly amenable t...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800406289909
更新日期：2006-07-01 00:00:00
abstract：:Delirium is a serious complication of acute illness. Little is known, however, regarding the neurobiology of delirium, largely due to challenges in studying the complex inpatient population. Neuroimaging is one noninvasive method that can be used to study structural and functional brain abnormalities associated with d...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800419849489
更新日期：2019-07-01 00:00:00
abstract：:Vaccination is one of our most powerful antiviral strategies. Despite the emergence of deadly viruses such as Ebola virus, vaccination efforts have focused mainly on childhood communicable diseases. Although Ebola virus was once believed to be limited to isolated outbreaks in distant lands, forces of globalization pot...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800403252574
更新日期：2003-04-01 00:00:00
abstract：BACKGROUND:Our program of research focuses on thermal and circulatory stability in extremely premature infants. In prior studies, we found that infants have long periods of time in which foot temperature (FT) is higher than central temperature. We thus wanted to determine whether blood flow in the foot is increased whe...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800416656914
更新日期：2017-01-01 00:00:00
abstract：:Cancer-related fatigue (CRF) is a multifactorial, biobehavioral phenomenon experienced by the majority of persons with cancer. It has negative consequences on the individual's physical functioning and quality of life. An array of biological, psychobehavioral, and functional mechanisms contributes to its occurrence. A ...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/1099800408324431
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Leptin and adiponectin, two adipokines involved in glucose and lipid metabolism, have been linked to regulation of growth in early infancy, energy balance, and metabolic disorders in childhood. The aim of this study was to determine if concentrations of leptin and adiponectin could be measured reliably in in...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800420973366
更新日期：2020-11-28 00:00:00
abstract：:The ability to maintain balance is often taken for granted, yet it is the foundation for mobility and overall functional independence throughout the life span. The purpose of this article is to define balance, review the components of balance, and describe common instruments used to measure balance. Clinical screening...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
doi：10.1177/109980040000100408
更新日期：2000-04-01 00:00:00
abstract：:Variations in sex hormones influence bone health in men. Aging in men is associated with a decrease in testosterone (T) levels. We examined the relationship between T levels and changes in bone health status as measured by quantitative ultrasound (QUS) at the phalanges and the os calcis and by peripheral bone mineral ...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800414532710
更新日期：2015-03-01 00:00:00
abstract：:The focus on a cure for childhood leukemia over the last three decades has resulted in survival rates of more than 80%. However, efforts to manage leukemia-treatment symptoms have not kept pace with new therapies. Symptom toxicity during treatment can result in complications, treatment delays, and therapy dose reducti...
journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2018-07-01 00:00:00
abstract：:The purposes of this quasi-experimental pilot study were to determine adherence to a 12-week group-based moderate-intensity walking program for sedentary adult outpatients with serious and persistent mental illness and to examine change from baseline to after the walking program in health status (mental and physical h...
journal_title：Biological research for nursing
pub_type： 临床试验,杂志文章
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更新日期：2005-10-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2017-07-01 00:00:00
abstract：:African American (AA) women are nearly twice as likely as non-Hispanic White (NHW) women to develop atherosclerosis associated with cardiovascular disease. Compelling evidence demonstrates that stress-related biomarkers, such as heat shock protein-70 (HSP70), are associated with increased atherosclerosis risk. Yet lit...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800413491422
更新日期：2014-07-01 00:00:00
abstract：:Benefits of daily physical activity are well known, but there are limited data to describe physical activity in heart failure patients who receive cardiac resynchronization therapy devices. The purpose of this pilot study was to evaluate changes in physical activity (PA) levels before and 3 months after Cardiac Resync...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800413481619
更新日期：2014-01-01 00:00:00
abstract：:Self-management programs that include cognitive behavioral strategies have been shown to improve gastrointestinal (GI) symptoms, psychological distress, and quality of life (QoL) in persons with irritable bowel syndrome (IBS). However, less is known about the physiological impact of such a change. As part of a randomi...
journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:We examined genomic variation potentially associated with the cortisol stress response in children having a painful medical procedure. DESIGN:Children 4-10 years old having a peripheral intravenous line inserted provided saliva samples for evaluation of the cortisol response as a biological measure of distre...
journal_title：Biological research for nursing
pub_type： 杂志文章
doi：10.1177/1099800419826315
更新日期：2019-03-01 00:00:00
abstract：:The purpose of this study was to compare physiological and psychological reactions among Taiwanese women with different degrees of severity of nausea and vomiting (NV) during pregnancy. Based on their scores on the Index of Nausea, Vomiting, and Retching (INVR), 59 pregnant women ≥ 18 years of age, with single gestati...
journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:To report the complexity and richness of study variables within biological nursing research, authors often use tables; however, the ease with which consumers understand, synthesize, evaluate, and build upon findings depends partly upon table design. OBJECTIVES:To assess and compare table characteristics wit...
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pub_type： 杂志文章
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更新日期：2018-01-01 00:00:00
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journal_title：Biological research for nursing
pub_type： 杂志文章
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abstract：:The effects of a 12-week low-intensity exercise conditioning program (walking) on blood pressure (BP), heart rate (HR), rate-pressure product (RPP), and cardiac autonomic function were measured in 40 sedentary women with hypertension. Women were assigned to either an exercise group (n = 20) or a control group (n = 20)...
journal_title：Biological research for nursing
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journal_title：Biological research for nursing
pub_type： 杂志文章
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abstract：INTRODUCTION:Plasma concentrations of lipids (i.e., total cholesterol, high-density cholesterol, low-density cholesterol, and triglycerides) are amenable to therapeutic intervention and remain important factors for assessing risk of cardiovascular diseases. Some of the observed variability in serum lipid concentrations...
journal_title：Biological research for nursing
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更新日期：2018-03-01 00:00:00
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journal_title：Biological research for nursing
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更新日期：2014-01-01 00:00:00
abstract：:Fatigue is the most frequently reported symptom by cancer patients. Many of these patients perceive fatigue as the most distressing symptom associated with their illness because it imposes limitations on their physical activity level. Skeletal muscle wasting, which occurs as part of cancer cachexia, is one of the mech...
journal_title：Biological research for nursing
pub_type： 杂志文章,评审
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更新日期：2001-01-01 00:00:00
abstract：OBJECTIVE:The Finnmarksløpet dogsled race lasts up to 7 days. Helpers, who keep time, coach, and transport equipment, have to be alert though they have little and fragmented sleep. This study investigated disruptions of the rest-activity rhythm among helpers. METHODS:10 helpers were monitored by actigraph a week befor...
journal_title：Biological research for nursing
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更新日期：2014-04-01 00:00:00
abstract：:Abdominal pain is an important symptom in irritable bowel syndrome (IBS), but patients report typical pain intensities ranging from mild to very severe. In a sample of women, the authors sought to determine whether measures of systemic autonomic activity are related to self-reported pain intensity and the occurrence o...
journal_title：Biological research for nursing
pub_type： 杂志文章
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更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:Proinflammatory activity has been suggested as one of the psychophysiological mechanisms responsible for the health risks associated with stress and mood disorders. There have been limited studies evaluating central immune and hypothalamic- pituitary-adrenal (HPA) axis responses to experimental stress in heal...
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更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Depression and inflammation are concomitantly elevated in patients with lung cancer and may have collective survival implications. However, the longitudinal relationship between depression and inflammation in patients with metastatic lung cancer is not fully appreciated. We hypothesized that longitudinal cha...
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更新日期：2020-09-22 00:00:00
abstract：OBJECTIVE:The sacral skin of bedridden older patients often develops a dysbiotic condition. To clarify whether the condition changes or is sustained over time, we analyzed the skin microbiome and the skin physiological functions of the sacral skin in patients who completed our 2017 study. METHODS:In 2019, we collected...
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更新日期：2021-01-01 00:00:00
