Abstract:
:African American (AA) women are nearly twice as likely as non-Hispanic White (NHW) women to develop atherosclerosis associated with cardiovascular disease. Compelling evidence demonstrates that stress-related biomarkers, such as heat shock protein-70 (HSP70), are associated with increased atherosclerosis risk. Yet little is known about how social factors such as perceived discrimination, subjective social status, and socioeconomic status contribute to the levels of these biomarkers in women with atherosclerosis. The aims of this pilot study were to (1) describe perceived everyday discrimination, subjective social status, perceived stress, and HSP70 level in AA and NHW women diagnosed with coronary or carotid artery disease requiring intervention and (2) determine the extent to which perceived discrimination, subjective social status, and perceived stress are associated with HSP70 level, controlling for age, education, and race. The sample for this cross-sectional, descriptive pilot study consisted of 10 AA and 21 NHW women admitted to the hospital for elective percutaneous cardiac intervention or carotid endarterectomy. Participants completed questionnaires measuring psychosocial variables and provided blood samples for analysis of HSP70. Race, age, education, perceived stress, perceived discrimination, and subjective social status significantly (p = .022) explained 34% of the variance in HSP70 levels. However, only subjective social status (p = .031) and AA race (p = .031) were significant independent predictors of HSP70 levels, with lower subjective social status and AA race associated with higher HSP70. Although larger studies are needed to confirm these results, findings imply that race and subjective social status may play an important role in predicting stress biomarker levels.
journal_name
Biol Res Nursjournal_title
Biological research for nursingauthors
Saban KL,Hoppensteadt D,Bryant FB,DeVon HAdoi
10.1177/1099800413491422subject
Has Abstractpub_date
2014-07-01 00:00:00pages
258-65issue
3eissn
1099-8004issn
1552-4175pii
1099800413491422journal_volume
16pub_type
杂志文章abstract::Survivors of aneurysmal subarachnoid hemorrhage (aSAH) often experience unfavorable functional outcomes that result in a reduced ability to independently perform activities of daily living. The apolipoprotein E gene ( APOE) encodes for a protein known to facilitate lipid transport and aid in neuronal repair within the...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417746504
更新日期:2018-03-01 00:00:00
abstract::During the menopausal transition and early postmenopause, participants in the Seattle Midlife Women's Health Study (SMWHS) experienced one of the three symptom severity clusters identified through latent class analysis: severe hot flashes with moderate sleep, mood, cognitive, and pain symptoms (high-severity hot flash...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417753536
更新日期:2018-03-01 00:00:00
abstract::To examine the effects of exercise and vitamin E supplementation on oxidative stress in older adults, 59 participants, age 76.3 +/- 4.2 years, were randomly assigned to 1 of 4 groups: an exercise group taking placebos (EGP) or vitamin E (EGE) or a sedentary group taking placebos (SGP) or vitamin E (SGE). Measures incl...
journal_title:Biological research for nursing
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/1099800403005001005
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVE:Although the roles of testosterone and cortisol in various health problems have been extensively investigated, little is known about their associations with health outcomes in mothers and their very-low-birthweight (VLBW) infants when maternal testosterone and cortisol are examined together during the postpar...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800417703704
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abstract::The ability to maintain balance is often taken for granted, yet it is the foundation for mobility and overall functional independence throughout the life span. The purpose of this article is to define balance, review the components of balance, and describe common instruments used to measure balance. Clinical screening...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/109980040000100408
更新日期:2000-04-01 00:00:00
abstract::Cytokines such as angiogenin (ANG) and interleukin (IL-8) have been shown to be related to depressive symptoms and inflammatory diseases like coronary heart disease. They may thus be used as stress biomarkers to identify and prevent health problems. To investigate the relationship between cytokines and nurses' job-rel...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800408323219
更新日期:2008-10-01 00:00:00
abstract::Research that uses a psychoneuroimmunology (PNI) framework seeks to determine whether valid associations exist among stress, immune function, and health. These associations are difficult to conclusively determine due to the fact that PNI research is fraught with methodological difficulties. These difficulties arise fr...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/10900402003004002
更新日期:2002-04-01 00:00:00
abstract:OBJECTIVE:The Finnmarksløpet dogsled race lasts up to 7 days. Helpers, who keep time, coach, and transport equipment, have to be alert though they have little and fragmented sleep. This study investigated disruptions of the rest-activity rhythm among helpers. METHODS:10 helpers were monitored by actigraph a week befor...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800412475077
更新日期:2014-04-01 00:00:00
abstract::Depression is the leading cause of disability worldwide, and its prevalence is 2 times higher in women than in men. There is, however, a lack of data on sex-specific pathophysiology of this disorder. The purpose of this systematic review is to identify the biological sex differences found in major depressive disorder ...
journal_title:Biological research for nursing
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doi:10.1177/1099800418776082
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journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800403262142
更新日期:2004-04-01 00:00:00
abstract::The current study was performed to evaluate the antinociceptive and antiedematogenic properties of andrographolide isolated from the leaves of Andrographis paniculata using two animal models. Antinociceptive activity was evaluated using the acetic acid- induced writhing and the hot-plate tests, while antiedematogenic ...
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journal_title:Biological research for nursing
pub_type: 杂志文章,随机对照试验
doi:10.1177/1099800412445907
更新日期:2013-10-01 00:00:00
abstract::Depression increases the risk of adverse cardiac events. Cardiovascular reactivity is defined as the pattern of cardiovascular responses to mental stress. An altered pattern of cardiovascular reactivity is an indicator of subsequent cardiovascular disease. Because depression and adverse cardiac events may have a dose-...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800415596227
更新日期:2016-03-01 00:00:00
abstract::The aim of this study was to investigate the effects of a resistance training program (RTP) in older overweight women (OOW) using two different types of elastic devices. METHODS:This study was a randomized controlled trial with pre- and postintervention measures. Participants included OOW, aged 60-85 years, with no m...
journal_title:Biological research for nursing
pub_type: 杂志文章,随机对照试验
doi:10.1177/1099800418757676
更新日期:2018-05-01 00:00:00
abstract::Scientists and clinicians frequently use immunological methods (IMs) to investigate complex biological phenomena. Commonly used IMs include immunocytochemistry (IC), enzyme-linked immunosorbent assays (ELISA) and flow cytometry. Each of these methodologies exploits a common principle in IMs -the binding of an antibody...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
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更新日期:2011-07-01 00:00:00
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journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800410362112
更新日期:2010-07-01 00:00:00
abstract::Society has a rapidly growing accumulative sleep debt due to employment obligations and lifestyle choices that limit sleep opportunities. The degree to which poor sleep may set the stage for adverse symptom outcomes among more than 1.7 million persons who will be diagnosed with cancer is not entirely understood. Pacli...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800414539385
更新日期:2015-03-01 00:00:00
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journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800418767572
更新日期:2018-07-01 00:00:00
abstract::Shift work schedules, intensive physical exercise late in the day, psychological stress, or a busy lifestyle might induce disorders of the circadian structure, which can affect health on both the physiological and neurobehavioral levels. Rest-activity rhythm is strongly connected with an organism's circadian structure...
journal_title:Biological research for nursing
pub_type: 杂志文章
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abstract::Despite high efficacy rates, significant costs and logistical challenges associated with procuring stool from healthy donors for fecal microbiota transplantation (FMT) have presented barriers to broader institutional adoption and limited the availability of this life-saving treatment. Published outcomes for donor scre...
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journal_title:Biological research for nursing
pub_type: 杂志文章,评审
doi:10.1177/1099800408320970
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:Application of a thermal stimulus is a common procedure used to promote venodilation for peripheral intravenous cannulation (PIVC); however, the effects of thermal stimulation on the duration of venodilation and skin temperature of the forearm are unclear. AIM:To investigate the duration of venodilation ind...
journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800416651145
更新日期:2017-03-01 00:00:00
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journal_title:Biological research for nursing
pub_type: 杂志文章
doi:10.1177/1099800409341175
更新日期:2010-01-01 00:00:00
abstract::The integration of molecular genetics approaches into the study of complex health phenomena is an increasingly important and available strategy for researchers across the health science disciplines. Pain sensation and response to painful stimuli are examples of complex health phenomena that are particularly amenable t...
journal_title:Biological research for nursing
pub_type: 杂志文章,评审
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更新日期:2006-07-01 00:00:00
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journal_title:Biological research for nursing
pub_type: 杂志文章
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更新日期:2019-03-01 00:00:00
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journal_title:Biological research for nursing
pub_type: 临床试验,杂志文章
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