Abstract:
:A critical molecular requirement underlying many forms of long-lasting synaptic plasticity and memory is the de novo synthesis of mRNAs and proteins. In a recent paper in Cell, Costa-Mattioli et al. present data from a pharmacogenetic study that places a key regulatory event in the "neural decision" to undergo these persistent neuronal changes under translational control mediated by eIF2alpha.
journal_name
Neuronjournal_title
Neuronauthors
Hoeffer CA,Klann Edoi
10.1016/j.neuron.2007.04.003subject
Has Abstractpub_date
2007-04-19 00:00:00pages
186-9issue
2eissn
0896-6273issn
1097-4199pii
S0896-6273(07)00253-Xjournal_volume
54pub_type
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