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On the enigma of pain and hyperalgesia: A molecular perspective.

Abstract：

:Pain is a common symptom of injuries and inflammatory-related conditions. The perception of pain, commonly known as nociception, depends on integrated receptors and molecular pathways. Inflammatory mediators are involved in the genesis, persistence, and severity of pain. Noxious stimuli can trigger a cascade of inflammatory loops that feedback onto sensory modalities and domains of the CNS, in an attempt to alert the brain of deregulated homeostasis. Understanding the mechanisms of pain continue to make nociception and hyperalgesia a burgeoning field of research.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Haddad JJ

doi

10.1016/j.bbrc.2006.12.032

subject

Has Abstract

pub_date

2007-02-09 00:00:00

pages

217-24

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(06)02685-4

journal_volume

353

pub_type

杂志文章,评审

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