Abstract:
PURPOSE:The purpose of this work was to determine whether the cellular components of Hairless-rat skin are affected by a chronic local exposure to non-ionizing radiations of Global Mobile Phone System: GSM-900 or -1800 radiations at specific absorption rate (SAR) 2.5 and 5 W/kg. MATERIALS AND METHODS:A selected part of the right back of five-week old female hairless rats was exposed or sham exposed (n = 8) for 2 h per day, 5 days a week, for 12 weeks to GSM-900 or -1800 signals using a loop-antenna. At the end of the experiment, skin biopsies were taken. RESULTS:Analyses of skin sections using hematoxylin eosin saffron (HES) coloration showed no significant difference in skin thickness among the groups. Immunohistochemical analysis of basal lamella cells in radiofrequency radiation (RFR)-exposed epidermis showed that the ratio of the antigen Ki-67 (cellular proliferation marker) positive cells to total lamella cells remained within the range of the normal proliferation ratio. No significant differences in the level of filaggrin, collagen, and elastin were observed among the different groups. CONCLUSIONS:The results of this 12-week chronic study do not demonstrate major histological variations in the skin of hairless rats exposed to RFR used in mobile telephony (GSM-900 or -1800).
journal_name
Int J Radiat Bioljournal_title
International journal of radiation biologyauthors
Sanchez S,Masuda H,Billaudel B,Haro E,Anane R,Lévêque P,Ruffie G,Lagroye I,Veyret Bdoi
10.1080/09553000600930087subject
Has Abstractpub_date
2006-09-01 00:00:00pages
675-80issue
9eissn
0955-3002issn
1362-3095pii
J428X51385243200journal_volume
82pub_type
杂志文章abstract:PURPOSE:To reduce retention and toxicity of the alpha particle emitter polonium-210 in rats by newly developed chelating agents. MATERIALS AND METHODS:Repeated subcutaneous chelation was conducted after intravenous injection of 210Po nitrate. For reduction of 210Po retention the treatment with vicinal dithiols meso-an...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553000050151691
更新日期:2000-10-01 00:00:00
abstract:PURPOSE:To identify and assess, among the participants in the RENEB (Realizing the European Network of Biodosimetry) project, the emergency preparedness, response capabilities and resources that can be deployed in the event of a radiological or nuclear accident/incident affecting a large number of individuals. These ca...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553002.2016.1227107
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To investigate within the framework of a multilaboratory study the suitability of FISH chromosome painting to measure so-called stable translocations in peripheral lymphocytes of Mayak nuclear-industrial workers (from the Southern Urals) and their use for retrospective biodosimetry. MATERIALS AND METHODS:Chrom...
journal_title:International journal of radiation biology
pub_type: 杂志文章,多中心研究
doi:10.1080/09553000010018693
更新日期:2001-03-01 00:00:00
abstract::The radiation response of 15 mammalian cell lines comprising 11 human tumour, two human fibroblast and two murine lymphoma cell lines, has been analysed using the linear-quadratic equation. As well as using conventional analysis of acute dose-survival curves to derive values for alpha and beta (termed alpha ac and bet...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553009214551241
更新日期:1992-04-01 00:00:00
abstract:PURPOSE:To determine the relationships between the frequencies of radiation-induced chromosomal alterations and the extent of apoptosis in G0 human lymphocytes. MATERIAL AND METHODS:G0 human peripheral blood lymphocytes (HPBL) were X or gamma-irradiated, in the presence or absence of the repair inhibitor cytosine arab...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553000500303690
更新日期:2005-08-01 00:00:00
abstract:PURPOSE:To study the natural radionuclides in the freshwater fish samples around the uranium mining areas of Bagjata and Banduhurang, East Singhbhum, Jharkhand, India. MATERIALS AND METHODS:The naturally occurring radioisotopes of uranium, U(nat), consisting of (234)U, (235)U and (238)U; (226)Ra, (230)Th and (210)Po w...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.3109/09553002.2010.492490
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To investigate physical and biophysical properties of proton tracks 1 keV-300 MeV using Monte Carlo track structure methods. MATERIALS AND METHODS:We present model calculations for cross sections and methods for simulations of full-slowing-down proton tracks. Protons and electrons were followed interaction-by-...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.3109/09553002.2010.518204
更新日期:2011-02-01 00:00:00
abstract:PURPOSE:To determine the contribution of intra-alveolar cells as opposed to cells fixed in the interstitium in the development of radiation-induced lung injury. MATERIALS AND METHODS:C3H/HeN mice were irradiated to the thorax with various doses of radiation. The cellular composition and cytokine production were assess...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/0955300031000076894
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:Effects of radiation on the differentiation of C2C12 myoblasts were studied using cell cultures in which the cells differentiated into either muscle cells or osteoblasts. MATERIALS AND METHODS:A mouse skeletal myoblast cell line, C2C12, was cultured and irradiated at confluence. Muscle differentiation was esti...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/095530000138745
更新日期:2000-03-01 00:00:00
abstract::The relative efficiencies of two types of densely ionizing particles were compared for the induction of mutations at two distinct genetic loci in human cells. Mutations to 6-thioguanine resistance (hgprt locus) or to trifluorothymidine resistance (tk) locus were scored in TK6 human lymphoblastoid cells exposed to grad...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553008914550961
更新日期:1989-06-01 00:00:00
abstract:PURPOSE:The hemorrhagic syndrome is a major cause of morbidity and mortality associated with the acute radiation syndrome (ARS). We previously characterized the dose-response relationship for total body irradiation (TBI)-induced ARS in the New Zealand White (NZW) rabbit. Thrombocytopenia, hemorrhage, and anemia were st...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553002.2020.1820601
更新日期:2020-10-16 00:00:00
abstract::The aim was to investigate further the relationship between radiation-induced mitotic delay and the expression of chromosome damage in V79 cells. Recently published data on the time-course of chromosome aberrations in V79 first-cycle metaphases after exposure to 10.4 MeV u(-1) Ar ions (LET = 1226 keV microm(-1)) were ...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553000400027902
更新日期:2005-01-01 00:00:00
abstract::We have measured clonal survival following gamma-irradiation of unstimulated (G0) T-lymphocytes from 35 donors, of 11 T-lymphocyte cell lines, of six lymphoblastoid cell lines, and of nine primary fibroblast strains for which we have G0 T-lymphocyte material from the same donor. Amongst the G0 lymphocytes we have resu...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553008814552331
更新日期:1988-12-01 00:00:00
abstract:PURPOSE:We already reported that levels of interferon (IFN)-γ have been shown to be markedly reduced in mice seven weeks after irradiation, resulting in a T helper (Th) 1/Th2 imbalance. To investigate whether the single or fractionated γ-irradiation induced an immune imbalance, we analysed the Th1-related immune respon...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.3109/09553002.2011.542540
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:The radiation-induced bystander effect (RIBE) has important implications for the efficiency of radiotherapy but the underlying role of cellular metabolism is widely unknown. The roles of synthesis of cytochrome c oxidase 2 (SCO2), a key effector for respiratory chain, and related signaling factors in α-particle...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.3109/09553002.2013.817706
更新日期:2013-12-01 00:00:00
abstract::Mouse C3H 10T1/2 cells are most sensitive to radiation-induced neoplastic transformation in the G2/M-phase of the cell cycle. When synchronized 10T1/2 cells were exposed to phorbol 12-myristate 13-acetate (TPA) after irradiation, transformation of cells not in the transformation-sensitive window was enhanced, but tran...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553009314551971
更新日期:1993-12-01 00:00:00
abstract::Intraoperative irradiation (IORT) is used to enhance local tumour control by using large, single doses while removing critical structures from the treatment field. Peripheral nerve remains a dose-limiting normal tissue that often cannot be removed from the field. To assess ultrastructural changes in canine sciatic ner...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553009514550941
更新日期:1995-07-01 00:00:00
abstract::The behaviour of polyamines (putrescine, spermidine and spermine) in the small intestine was studied in rats exposed to a single whole-body dose of 3 Gy administered at four different times of the day. Polyamine content decreased a few hours after irradiation but quickly returned to normal values. Putrescine levels re...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553008914551191
更新日期:1989-07-01 00:00:00
abstract:PURPOSE:Conditionally Replicative Adenovirus (CRAd) has been previously demonstrated to augment the activity of radiation, resulting in synergy of cell kill. However, previous models combining radiation with CRAd have not focused on the methods of radiation delivery. MATERIALS AND METHODS:We model the combination of a...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.3109/09553000903419338
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:Following ionizing radiation exposure, intestinal crypt regeneration is possible but it is still not known if regenerating crypts give rise to differentiated functional epithelial cells on villi. The aim of this study was to demonstrate that irradiated progeny of enterocytic precursor cells are capable of proli...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553000500091923
更新日期:2005-03-01 00:00:00
abstract::Wet heat shock (60 degrees C, 90 s) and caffeine (3.8 X 10(-4) M) afford significant radioprotection against post-irradiation O2-dependent damage which develops in seeds of approximately 3.5% moisture content. The damage was assessed in terms of seedling injury on the eighth day of growth. An increase in seedling inju...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553009114551101
更新日期:1991-05-01 00:00:00
abstract:PURPOSE:This study evaluates early changes in human mesenchymal stem cells (MSC) isolated from dental pulp and periodontal ligament after γ-irradiation and the effect of ataxia-telangiectasia mutated (ATM) inhibition. METHODS:MSC were irradiated with 2 and 20 Gy by (60)Co. For ATM inhibition, specific inhibitor KU5593...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.3109/09553002.2013.775530
更新日期:2013-07-01 00:00:00
abstract::Radiation survival curves have been obtained for crypts in the small and large intestine of male BDF1 mice using the microcolony assay. Four regions of the small intestine and three regions of the large intestine were studied. One of the major objectives was to determine the optimal conditions for the microcolony assa...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/095530097144265
更新日期:1997-02-01 00:00:00
abstract:PURPOSE:To obtain compounds that will effectively reduce the fixation of uranium in its main target organs: bone and kidney. There is an urgent need for a chelating agent that is suitable and available for human use. MATERIALS AND METHODS:The efficacy of ethane-1-hydroxy-1,1-bisphosphonate (EHBP), already in use as a ...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/095530099139331
更新日期:1999-11-01 00:00:00
abstract:PURPOSE:To compare colony-forming and comet assays on fibroblasts and lymphocytes of 32 breast cancer patients irradiated after breast-conserving operations and to correlate the results with acute clinical radiation reactions in the skin. MATERIAL AND METHODS:Skin fibroblasts were isolated and cultivated before radiot...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553000210126466
更新日期:2002-07-01 00:00:00
abstract::CHEF-electrophoresis was used as a technique to detect radiation-induced DNA breakage with special emphasis to biological relevant X-ray doses (0-10 Gy). Fluorescence detection of DNA-fragments using a sensitive image analysis system was directly compared with conventional scintillation counting of 3H-thymidine prelab...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553009314551361
更新日期:1993-08-01 00:00:00
abstract::The effect of local stimulation on mitotic activity and radiation tolerance was studied in mouse tongue mucosa. Silver nitrate solution (0.5-20%) was used for local conditioning. The most effective protocol comprised three daily treatments (days 0-2), yielding a delayed increase in 24 h mitotic counts by about 30% on ...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553009214551061
更新日期:1992-03-01 00:00:00
abstract:PURPOSE:The increased bioactivity 'windows' of GSM 900 and 1800 MHz radiations, (Global System for Mobile telecommunications) revealed recently by us and published in this issue, manifesting themselves as a maximum decrease in the reproductive capacity of the insect Drosophila melanogaster, were examined to discover wh...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.3109/09553000903567979
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:To investigate the p53 ionizing radiation-induced response, G1/S cell-cycle block and cytogenetic damage in Nijmegen breakage syndrome (NBS) cells characterized by different haplotypes. MATERIAL AND METHODS:Lymphoblastoid cell lines derived from three normals, five NBS and two ataxia telangiectasia (AT) indivi...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/095530099140221
更新日期:1999-05-01 00:00:00
abstract:PURPOSE:To evaluate the cumulative gamma-radiation personal exposure by analysing lymphocyte chromosome translocations using FISH painting and to compare FISH-derived biodoses with those derived from retrospective physical dose reconstruction in residents receiving chronic low dose-rate gamma-irradiation while living i...
journal_title:International journal of radiation biology
pub_type: 杂志文章
doi:10.1080/09553000110053873
更新日期:2001-07-01 00:00:00