Abstract：
:: We report heritabilities for individual differences in female pubertal development at the age of 12. Tanner data on breast and pubic hair development in girls and data on menarche were obtained from a total of 184 pairs of monozygotic and dizygotic twins. Genetic correlations were estimated to determine to what extent the same genes are involved in different aspects of physical development in puberty. A Bayesian estimation approach was taken, using Markov-chain Monte Carlo simulation to estimate model parameters. All three phenotypes were to a significant extent heritable and showed high genetic correlations, suggesting that a common set of genes is involved in the timing of puberty in general. However, gonadarche (menarche and breast development) and adrenarche (pubic hair) are affected by different environmental factors, which does not support the three phenotypes to be regarded as indicators of a unitary physiological factor.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
van den Berg SM,Setiawan A,Bartels M,Polderman TJ,van der Vaart AW,Boomsma DIdoi
10.1007/s10519-005-9022-ysubject
Has Abstractpub_date
2006-03-01 00:00:00pages
261-70issue
2eissn
0001-8244issn
1573-3297journal_volume
36pub_type
杂志文章abstract：:Biometric studies have shown that happiness is strongly affected by genes. The findings are mainly based on twin data, however, and the full validity of the results has been debated. To overcome some limitations in classical twin research, we examined aetiological sources of subjective well-being (SWB), using two inde...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9365-x
更新日期：2010-09-01 00:00:00
abstract：:A genetic analysis of differences in reactivity to early exposure of female BALB/cBy and C57BL/6By mice to testosterone was performed using the C x B recombinant-inbred (RI) strains. RI female mice were given a single injection of 1 mg of testosterone propionate on day 4 of life and observed in adulthood in the presen...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01070741
更新日期：1990-01-01 00:00:00
abstract：:The zebrafish enjoys several advantages over other model organisms. It is small, easy to maintain, prolific, and numerous genetic tools are available for it. For example, forward genetic screens have allowed investigators to identify important genes potentially involved in a variety of functions from embryogenesis to ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-016-9818-y
更新日期：2017-01-01 00:00:00
abstract：:We report analyses of data on body fat from a cohort of 34 separated monozygotic twin pairs (MZA) and a matched sample of 38 pairs of monozygotic twins reared together (MZT) originally studied by James Shields. The correlation for MZA pairs was .61 and the correlation for MZT pairs was .75. These correlations did not ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01067662
更新日期：1991-01-01 00:00:00
abstract：:Latent variable models are used in biological and social sciences to investigate characteristics that are not directly measurable. The generation of individual scores of latent variables can simplify subsequent analyses. However, missing measurements in real data complicate the calculation of scores. Missing observati...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-006-9123-2
更新日期：2007-03-01 00:00:00
abstract：:Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9-14 to examine the reliability and heritab...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-016-9831-1
更新日期：2017-03-01 00:00:00
abstract：:Parameters of quantitative genetic models have traditionally been estimated by either algebraic manipulation of familial correlations (or familial mean squares), biometric model fitting, or multiple-group covariance structure analysis. With few exceptions, researchers who have used these methods for the analysis of tw...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066662
更新日期：1992-05-01 00:00:00
abstract：:Interpretation of studies using single gene mutants is complicated by possible epistatic interactions with genetic background. Dopamine D2 receptor (Drd2) knockout mice on a C57BL/6 (B6) background show decreased basal locomotion, ethanol preference and ethanol-induced ataxia. Epistatic interactions were studied by ex...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1023450625826
更新日期：2003-05-01 00:00:00
abstract：:Chickens homozygous for the Dominant white or wild-type allele of PMEL17 were subjected to a broad phenotyping in order to detect consistent differences between genotypes. To exclude feather pecking, the chickens were individually housed without physical contact, from the day of hatching, and tested for social, aggres...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9379-4
更新日期：2011-03-01 00:00:00
abstract：:A genome-wide linkage scan of 795 microsatellite markers (761 autosomal, 34 X chromosome) was performed on Multidimensional Aptitude Battery subtests and verbal, performance and full scale scores, the WAIS-R Digit Symbol subtest, and two word-recognition tests (Schonell Graded Word Reading Test, Cambridge Contextual R...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-005-9003-1
更新日期：2006-01-01 00:00:00
abstract：:To study the relationship between genetics and epilepsy, Wistar rats susceptible to audiogenic seizure were selected from the main breeding stock of the Ribeirão Preto School of Medicine at the University of São Paulo, Brazil, and inbred. The criteria for selection were the highest seizure severity index (SI) and shor...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1021099432759
更新日期：2003-01-01 00:00:00
abstract：:Feather pecking (FP) is a serious economic and welfare problem in the domestic fowl. It has recently been shown that the distribution of FP bouts within groups is heterogeneous and contains a sub-population of extreme feather peckers (EFP). The present study proposed a novel model to detect EFP hens. A mixture of two ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-019-09971-w
更新日期：2020-01-01 00:00:00
abstract：:Cannabis use is linked to positive and negative outcomes. Identifying genetic targets of susceptibility to the negative effects of cannabinoid use is of growing importance. The current study sought to complete short-term selective breeding for adolescent sensitivity and resistance to the locomotor effects of a single ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-018-9894-2
更新日期：2018-05-01 00:00:00
abstract：:The non-synonymous SNP rs2228145 in the IL6R gene on chromosome 1q21.3 is associated with a wide range of common diseases, including asthma, rheumatoid arthritis, type 1 diabetes and coronary heart disease. We examined the contribution of this functional IL6R gene polymorphism rs2228145 versus other genome-wide SNPs t...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9656-8
更新日期：2014-07-01 00:00:00
abstract：:Two separate genome-wide association studies were conducted to identify single nucleotide polymorphisms (SNPs) associated with social and nonsocial autistic-like traits. We predicted that we would find SNPs associated with social and non-social autistic-like traits and that different SNPs would be associated with soci...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-009-9308-6
更新日期：2010-01-01 00:00:00
abstract：:Substantial progress has been made recently in analyses of longitudinal twin and family data, principally for two reasons. The first is the continuing development of more refined models for describing longitudinal data; the second is the widespread availability of analytic methods (e.g. LISREL) with which to implement...
journal_title：Behavior genetics
pub_type： 评论,杂志文章
doi：10.1007/BF01067000
更新日期：1992-03-01 00:00:00
abstract：:Here we provide a detailed description of the genome-wide information available on the National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pair subsample (Harris et al. in Twin Res Hum Genet 16:391-398, 2013). A total of 2,020 samples were genotyped (including duplicates) arising from 1946 A...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9692-4
更新日期：2015-01-01 00:00:00
abstract：:Genome wide complex trait analysis (GCTA) is extended to include environmental effects of the maternal genotype on offspring phenotype ("maternal effects", M-GCTA). The model includes parameters for the direct effects of the offspring genotype, maternal effects and the covariance between direct and maternal effects. A...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9666-6
更新日期：2014-09-01 00:00:00
abstract：:The region containing ROBO1 (Chromosome 3p12.3) has been implicated as a susceptibility gene for reading disorder and language deficit by translocation and linkage data. No association studies have yet been reported supporting any candidate gene. Here we report the first association of this gene with language deficits...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-010-9402-9
更新日期：2011-01-01 00:00:00
abstract：:Manipulation of endogenous levels of the GABAergic neurosteroid allopregnanolone alters sensitivity to some effects of ethanol. Chronic ethanol withdrawal decreases activity and expression of 5α-reductase-1, an important enzyme in allopregnanolone biosynthesis encoded by the 5α-reductase-1 gene (Srd5a1). The present s...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-014-9691-5
更新日期：2015-05-01 00:00:00
abstract：:We examined longitudinally collected behavioral reports by teachers on a unique twin sample at the ages of 7, 8, 9, 10, 11, and 12 years. As twin and adoption studies implicate the role of genetic influence on behavioral problems found to be stable in epidemiological samples, the current study employs a developmental ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-004-1747-5
更新日期：2005-07-01 00:00:00
abstract：:During middle childhood, continuous changes occur in electroencephalogram (EEG) coherence, an index of cortico-cortical connectivity of the brain. In the gradual development of EEG coher ence, occasional "growth spurts" are observed which coincide with periods of discontinuous development in cognition. Discontinuous d...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1013357714500
更新日期：2001-11-01 00:00:00
abstract：:The amygdala integrates and coordinates emotional and autonomic responses. The genetics that underlie variation in amygdala structure may be coupled to variation in levels of aggression, fear, anxiety, and affiliated behaviors. We systematically quantified the volume and cell populations of the basolateral amygdala co...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-006-9122-3
更新日期：2007-01-01 00:00:00
abstract：:The transmission of social attitudes has been investigated as a possible model of cultural inheritance in a sample of 3810 twin pairs from the Australian National Health and Medical Research Twin Registry. Six social attitude factors were identified and univariate genetic models fitted to scores on each factor. A join...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01066792
更新日期：1992-01-01 00:00:00
abstract：:The conditioned and reflex parameters in rat lines selected for the threshold of excitability (a fundamental characteristics of the functional state of the nervous system) were estimated. This measure is based on the response of the tibial nerve to electrical stimulation, which gives a general indication of the level ...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01067986
更新日期：1993-09-01 00:00:00
abstract：:Fingerprints and handedness were measured in 2169 subjects. Left-handers were more likely to have an increased number of arches and radial loops, while having fewer whorls and lower pattern intensity than right-handers. Analyzing by hand and digit, the differences were most marked on the left hand, which showed signif...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/BF01067817
更新日期：1994-03-01 00:00:00
abstract：:In an investigation into the effects of developmental isolation from all conspecifics, the Drosophila willistoni group of six sibling species responded to differing degrees: all six are reproductively isolated from D. paulistorum, the tester species. Drosophila pavlovskiana, a narrow endemic, proved the most vulnerabl...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1023/a:1021494023660
更新日期：1999-01-01 00:00:00
abstract：:The facts concerning Kammerer's case are reviewed. Koestler's view that Krammerer was unjustly accused is presented and shown to be incorrect. ...
journal_title：Behavior genetics
pub_type： 传,历史文章,杂志文章
doi：10.1007/BF01066805
更新日期：1975-04-01 00:00:00
abstract：:Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats are selected and bred for extreme divergence in two-way active avoidance acquisition. In addition, compared to RLA/Verh rats, RHA/Verh rats are (behaviorally and physiologically) less anxious or reactive to stressors, show increased novelty (sensation)-seeking...
journal_title：Behavior genetics
pub_type： 杂志文章,评审
doi：10.1023/a:1021400830503
更新日期：1997-11-01 00:00:00
abstract：:Testis specific protein, Y-encoded-like 2 (TSPYL2) regulates the expression of genes encoding glutamate receptors. Glutamate pathology is implicated in neurodevelopmental conditions such as autism spectrum disorder, attention deficit hyperactivity disorder (ADHD) and schizophrenia. In line with this, a microduplicatio...
journal_title：Behavior genetics
pub_type： 杂志文章
doi：10.1007/s10519-015-9777-8
更新日期：2016-07-01 00:00:00
