Abstract:
:This review describes recent developments in microfabricated flow cytometers and related microfluidic devices that can detect, analyze, and sort cells or particles. The high-speed analytical capabilities of flow cytometry depend on the cooperative use of microfluidics, optics and electronics. Along with the improvement of other components, replacement of conventional glass capillary-based fluidics with microfluidic sample handling systems operating in microfabricated structures enables volume- and power-efficient, inexpensive and flexible analysis of particulate samples. In this review, we present various efforts that take advantage of novel microscale flow phenomena and microfabrication techniques to build microfluidic cell analysis systems.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Huh D,Gu W,Kamotani Y,Grotberg JB,Takayama Sdoi
10.1088/0967-3334/26/3/R02subject
Has Abstractpub_date
2005-06-01 00:00:00pages
R73-98issue
3eissn
0967-3334issn
1361-6579pii
S0967-3334(05)85153-6journal_volume
26pub_type
杂志文章,评审abstract::Non-contact vital sign monitoring enables the estimation of vital signs, such as heart rate, respiratory rate and oxygen saturation (SpO2), by measuring subtle color changes on the skin surface using a video camera. For patients in a hospital ward, the main challenges in the development of continuous and robust non-co...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab525c
更新日期:2019-12-02 00:00:00
abstract::In this study, the selection of coil configuration parameters (coil radius and coil centre shift) for induced current EIT using circular coils is investigated. An alternative coil configuration is suggested, which produces approximately linear (spatially) magnetic fields in order to strengthen the currents in the cent...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/15/2a/007
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Walking is a complex human behavior, usually performed in a dynamic environment. Gait parameters are thought to reflect this complexity. Re-Step™ is a therapy system in the form of a computerized shoe, originally developed for the training and rehabilitation of individuals with brain damage. Th...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/1361-6579/aab659
更新日期:2018-04-26 00:00:00
abstract::A new method for the measurement of pulmonary gas exchange during inhalational anaesthesia is described which measures fresh gas and exhaust gas flows using carbon dioxide as an extractable marker gas. The theoretical precision of the method was compared by Monte Carlo modelling with other approaches which use marker ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/25/1/001
更新日期:2004-02-01 00:00:00
abstract::Cooperative sensors is a novel measurement architecture that allows the acquiring of biopotential signals on patients in a comfortable and easy-to-integrate manner. The novel sensors are defined as cooperative in the sense that at least two of them work in concert to measure a target physiological signal, such as a mu...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/4/767
更新日期:2015-04-01 00:00:00
abstract::A gamma fit facilitates smoothing and extrapolation of distorted tracer-dilution curves in blood flow studies. Theoretically based empirical estimators were developed as simple alternatives to direct regression approaches from simulated gamma distributions with a wide range of shape asymmetry. Key curve features of pe...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/4/401
更新日期:2001-11-01 00:00:00
abstract::High-frequency (HF) oscillations in RR interval from 0.15-0.40 Hz are widely accepted as a measure of cardiac vagal outflow but the HF/RR relationship appears complex, particularly with longer RR intervals. The aim of this study was to evaluate the HF/RR interval relationship during free and paced breathing. HF power ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/7/008
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVE:Plots of blood volume measurements over time (profiles) may identify euvolemia during fluid removal for acute heart failure. We assessed agreement between two noninvasive measurements of blood volume profiles during mechanical fluid removal, which exemplifies the interstitial fluid shifts that occur during di...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab21af
更新日期:2019-07-01 00:00:00
abstract::Multiple frequency bio-electrical impedance analysis (MFBIA) may be useful for monitoring fluid balance in newborn infants or to provide early prediction of the outcome following perinatal asphyxia. A reference range of data is needed for identification of babies with abnormal impedance values. This was a cross-sectio...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/11/010
更新日期:2006-11-01 00:00:00
abstract::Urinary catheters (drainage tubes) are in widespread use. The most common type of long-term catheter is the Foley, which is made from natural or synthetic rubber. Foley catheters are passed into the bladder via the urethra or the suprapubic puncture channel (through the abdominal wall). A simulator for the abdominal w...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/3/308
更新日期:2001-08-01 00:00:00
abstract::A new method to image and quantify intra-abdominal haemorrhage using electrical impedance tomography (EIT) was tested in vivo. Supine peritoneal dialysis patients were monitored using an 8-electrode hemiarray placed on the anterior abdomen. EIT measurements were recorded using the EPack II data acquisition system befo...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/2/001
更新日期:2011-02-01 00:00:00
abstract::The back-projected independent components (BICs) of single-trial, auditory P300 and contingent negative variation (CNV) evoked potentials (EPs) were derived using independent component analysis (ICA) and cluster analysis. The method was tested in simulation including a study of the electric dipole equivalents of the s...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/8/001
更新日期:2007-08-01 00:00:00
abstract::This paper represents a reconstruction algorithm using a direct sensitivity matrix (DSM) approach for fast 3D image reconstruction in electrical impedance imaging. The boundary element method (BEM) is used in the construction of this matrix. The first images of a conductivity perturbation inside a sphere are reconstru...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/16/3a/012
更新日期:1995-08-01 00:00:00
abstract::In order to detect minute amounts of glucose in diluted urine, we applied the Raman spectroscopy method. To simulate abnormal diluted urine in a toilet bowl, we diluted normal urine ten-fold with water and added glucose up to 8 mg dl(-1). Data were collected using a low-resolution Raman spectrometer that was preproces...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/5/011
更新日期:2007-05-01 00:00:00
abstract::Electrical impedance tomography (EIT) has shown significant promise for lung imaging. One key challenge for EIT in this application is the movement of electrodes during breathing, which introduces artefacts in reconstructed images. Various approaches have been proposed to compensate for electrode movement, but no comp...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/6/1119
更新日期:2015-06-01 00:00:00
abstract::Electrical impedance spectroscopy has been developed as a potential method for the diagnosis of carcinoma in epithelial tissues. An understanding of the influence of structural changes in the tissue on the properties measured using this technique is essential for interpreting measured data and optimization of probe de...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/3/010
更新日期:2005-06-01 00:00:00
abstract::Temporal changes in the impedance spectra of bioelectrodes in contact with skin provide useful data for comparisons between differing electrode materials and skin preparation methods. Traditional impedance measuring systems employ swept frequency methods which will distort results in the impedance spectra of a sample ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/20/1/008
更新日期:1999-02-01 00:00:00
abstract::In this paper we present a method for recognising three fundamental movements of the human arm (reach and retrieve, lift cup to mouth, rotation of the arm) by determining the orientation of a tri-axial accelerometer located near the wrist. Our objective is to detect the occurrence of such movements performed with the ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/9/1751
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To compare a novel cardiovascular magnetic resonance technique for the assessment of left ventricular (LV) mechanical discoordination by characterizing the endocardial center motion (ECM) in short-axis cine MRI in healthy volunteers and heart failure patients with left bundle branch block (HF-LBBB). APPROACH...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaaaa0
更新日期:2018-02-28 00:00:00
abstract::An analytic solution of the potential distribution on a 2D homogeneous disk for electrical impedance tomography under the complete electrode model is expressed via an infinite system of linear equations. For the shunt electrode model with two electrodes, our solution coincides with the previously derived solution expr...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/9/008
更新日期:2011-09-01 00:00:00
abstract::External defibrillation requires the application of high voltage electrical impulses via large external electrodes, placed on selected locations on the thorax surface. The position of the electrodes is one of the major determinants of the transthoracic impedance (TTI) which influences the intracardiac current flow dur...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/10/007
更新日期:2006-10-01 00:00:00
abstract::Extension of the frequency range of electrical impedance myography (EIM) to 2 MHz discloses a major rise in the reactance of muscle above 3-500 kHz, together with a slow decrease in the resistance consonant with the Kramers-Kronig relations. This 'upturn' phenomenon is found when the distant current electrode configur...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/29/6/S29
更新日期:2008-06-01 00:00:00
abstract::Balance is the ability to maintain equilibrium while sitting or standing. There are a number of different methods which are used to assess balance: technical methods such as sway magnetometry, ataxia meter and force platforms, and clinical methods such as the functional reach test, Berg balance test and fall risk inde...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/21/4/309
更新日期:2000-11-01 00:00:00
abstract::Agitation is a significant problem in the intensive care unit (ICU), affecting 71% of sedated adult patients during 58% of ICU patient-days (Fraser and Riker 2001 NY Health-Syst. Pharm. 20 17-24). Subjective scale-based assessment methods are currently used to assess the level of patient agitation, but are limited in ...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/25/4/020
更新日期:2004-08-01 00:00:00
abstract::Neural gastric electrical stimulation (NGES) is a new method for invoking gastric contractions under microprocessor control. However, optimization of this technique using feedback mechanisms to minimize power consumption and maximize effectiveness has been lacking. The present pilot study proposes a prototype feedback...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/30/3/006
更新日期:2009-03-01 00:00:00
abstract::There are currently no objective means of quantifying chest wall vibrations during manual physiotherapy. The aims of the study were to (i) develop a method to quantify physiotherapy-applied forces and simultaneous changes in respiratory flow and pressure, (ii) assess the feasibility of using this method in ventilated ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/9/004
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:Non-contact physiological measurement is a growing research area that allows capturing vital signs such as heart rate (HR) and breathing rate (BR) comfortably and unobtrusively with remote devices. However, most of the approaches work only in bright environments in which subtle photoplethysmographic and balli...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aae625
更新日期:2018-10-30 00:00:00
abstract::In electrical impedance tomography (EIT) two-dimensional models continue to be applied despite their known inability to provide correct reconstruction. In this paper, a reconstruction algorithm that assumes a translationally invariant conductivity distribution is described. A more precise forward solver is obtained by...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/21/1/308
更新日期:2000-02-01 00:00:00
abstract::Twenty-nine patients were monitored overnight for breathing distress patterns during postoperative analgesia. Nasal flow apnoea monitoring and pulse oximetry data were recorded at 50 Hz. Respiratory inductive plethysmography (RIP) tracked tidal volume (TV) thoracoabdominal motion, and supplemented the flow monitoring ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/20/2/307
更新日期:1999-05-01 00:00:00
abstract::The aim of the study was to investigate whether body mass index (BMI) influences the estimation of extracellular volume (ECV) in hemodialysis (HD) patients when using segmental bioimpedance analysis (SBIA) compared to wrist-to-ankle bioimpedance analysis (WBIA) during HD with ultrafiltration (UF). Twenty five HD patie...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/26/2/009
更新日期:2005-04-01 00:00:00