Automatic sleep-stage scoring based on photoplethysmographic signals.


OBJECTIVE:Sleep-stage scoring is important for sleep-quality evaluation and the diagnosis of related diseases. In this study, an automatic sleep-stage scoring method using photoplethysmographic (PPG) signals was proposed. APPROACH:To construct the classification model, we extracted 14 time-domain features, 17 frequency-domain features, and 20 pulse rate variability (PRV) features along with four SpO2 features from PPG signals. An artificial neural network classifier was used to integrate the results of ten binary support vector machine classifiers and realise sleep-stage classification. Leave-one-subject-out validation was applied to evaluate our proposed model. MAIN RESULTS:Thirty-one subjects were enrolled in the study, in which 21 subjects were with high sleep quality (sleep efficiencies ⩾85%). Our model achieved accuracies of 57% (κ = 0.39), 62% (κ = 0.41), and 78% (κ = 0.54) for the classification of five sleep stages (wake, N1, N2, N3, and rapid eye movement (REM) sleeps), four sleep stages (wake, light, deep, and REM sleeps) and three sleep stages (wake, non-rapid eye movement (NREM), and REM sleeps), respectively. For the remaining ten subjects with poor sleep quality, the results came to 55% (κ = 0.39), 62% (κ = 0.43), and 75% (κ = 0.52). SIGNIFICANCE:The satisfactory performance of our proposed model reveals the potential of PPG signals for sleep-stage scoring, which may contribute to automatic sleep monitoring in the home environment.


Physiol Meas


Wu X,Yang J,Pan Y,Zhang X,Luo Y




Has Abstract


2020-06-30 00:00:00












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    journal_title:Physiological measurement

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    authors: Belal SY,Taktak AF,Nevill A,Spencer A

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  • A measurement of pulmonary blood volume increase during systole in humans.

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    journal_title:Physiological measurement

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    journal_title:Physiological measurement

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    authors: Mensah-Brown NA,Lutter WJ,Comani S,Strasburger JF,Wakai RT

    更新日期:2011-01-01 00:00:00

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    abstract:OBJECTIVE:Accurate bladder size estimation is an important clinical parameter that assists physicians, enabling them to provide better treatment for patients who are suffering from urinary incontinence. Electrical impedance tomography (EIT) is a non-invasive medical imaging method that estimates organ boundaries assumi...

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    authors: Konki SK,Khambampati AK,Sharma SK,Kim KY

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    abstract::Measurement of the velocity of propagation and attenuation of ultrasound (200 kHz) is believed to be a useful non-invasive technique for assessing the mechanical properties of bone. A new method for the determination of ultrasound velocity and attenuation of longitudinal waves in cortical bone was used in vivo and in ...

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    authors: Saulgozis J,Pontaga I,Lowet G,Van der Perre G

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  • Reproducibility of regional lung ventilation distribution determined by electrical impedance tomography during mechanical ventilation.

    abstract::Electrical impedance tomography (EIT) has the potential to become a new tool for bedside monitoring of regional lung ventilation. The aim of our study was to assess the reproducibility of regional lung ventilation distribution determined by EIT during mechanical ventilation under identical ventilator settings. The exp...

    journal_title:Physiological measurement

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    authors: Frerichs I,Schmitz G,Pulletz S,Schädler D,Zick G,Scholz J,Weiler N

    更新日期:2007-07-01 00:00:00

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    abstract::Agitation is a significant problem in the intensive care unit (ICU), affecting 71% of sedated adult patients during 58% of ICU patient-days (Fraser and Riker 2001 NY Health-Syst. Pharm. 20 17-24). Subjective scale-based assessment methods are currently used to assess the level of patient agitation, but are limited in ...

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    authors: Chase JG,Starfinger C,Lam Z,Agogue F,Shaw GM

    更新日期:2004-08-01 00:00:00

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    abstract::Spectral analysis of heart rate variability (HRV) is used for the assessment of cardiovascular autonomic control. In this study, a data-driven adaptive technique called empirical mode decomposition (EMD) and the associated Hilbert spectrum has been used to evaluate the effect of local anaesthesia on HRV parameters in ...

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    authors: Shafqat K,Pal SK,Kumari S,Kyriacou PA

    更新日期:2011-04-01 00:00:00

  • Design considerations and performance of a prototype system for imaging neuronal depolarization in the brain using 'direct current' electrical resistance tomography.

    abstract::The ability to image the impedance changes that accompany neuronal depolarization in the brain would constitute a major advance in neuroscience technology. Unfortunately, these changes are likely to be small and rapid and so difficult to measure. The impedance change at frequencies above 10 kHz, as used by conventiona...

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    authors: Boone KG,Holder DS

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  • A method for modelling and optimizing an electrical impedance tomography system.

    abstract::Electrical impedance tomography (EIT) image reconstruction is an ill-posed problem requiring maximum measurement precision. Recent EIT systems claim 60 to 80 dB precision. Achieving higher values is hard in practice since measurements must be performed at relatively high frequency, on a living subject, while using com...

    journal_title:Physiological measurement

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    authors: Hartinger AE,Gagnon H,Guardo R

    更新日期:2006-05-01 00:00:00

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    abstract::Gastro-oesophageal pH measurements are routinely carried out to quantify and determine if levels of acid reflux are responsible for symptoms. Although considered the 'gold standard', evidence suggests that pH measurements do not correlate well with the degree of oesophagitis seen during endoscopy. In this study the cu...

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    authors: Haylett KR,Vales P,Lee SH,McCloy RF

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    authors: Spanel P,Wang T,Smith D

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    authors: Nuutinen J,Ikäheimo R,Lahtinen T

    更新日期:2004-04-01 00:00:00

  • Circuit modeling of the electrical impedance: II. Normal subjects and system reproducibility.

    abstract::Part I of this series showed that the five-element circuit model accurately mimics impedances measured using multi-frequency electrical impedance myography (MFEIM), focusing on changes brought on by disease. This paper addresses two requirements which must be met if the method is to qualify for clinical use. First, th...

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    authors: Hovorka R,Canonico V,Chassin LJ,Haueter U,Massi-Benedetti M,Orsini Federici M,Pieber TR,Schaller HC,Schaupp L,Vering T,Wilinska ME

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    abstract::Temporal changes in the impedance spectra of bioelectrodes in contact with skin provide useful data for comparisons between differing electrode materials and skin preparation methods. Traditional impedance measuring systems employ swept frequency methods which will distort results in the impedance spectra of a sample ...

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    authors: Searle A,Kirkup L

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    abstract::Measurement of intracranial pressure (ICP) can be invaluable in the management of critically ill patients. Cerebrospinal fluid is produced by the choroid plexus in the brain ventricles (a set of communicating chambers), after which it circulates through the different ventricles and exits into the subarachnoid space ar...

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    authors: Pelizzone M

    更新日期:1993-11-01 00:00:00

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    abstract::Cycling on an ergometer is one effective means of measuring cardiovascular function while applying stress on the heart. Bathing in a hot water bath applies a low stress to the heart. The electrocardiograms of a healthy adult male (aged 35 at the start of study) were recorded while taking a hot water bath with no elect...

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    authors: Ishijima M,Togawa T

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  • The influence of cardiac preload and positive end-expiratory pressure on the pre-ejection period.

    abstract::The pre-ejection period (PEP) has recently been described as a potential parameter for monitoring cardiac preload. This study further investigated the influence of changes in intravascular volume status and the application of positive end-expiratory pressure (PEEP) on the pre-ejection period. In ten pigs, ECG, arteria...

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    authors: Kubitz JC,Kemming GI,Schultheib G,Starke J,Podtschaske A,Goetz AE,Reuter DA

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  • In vivo bioimpedance changes during haemorrhagic and ischaemic stroke in rats: towards 3D stroke imaging using electrical impedance tomography.

    abstract::Electrical impedance tomography (EIT) could be used as a portable non-invasive means to image the development of ischaemic stroke or haemorrhage. The purpose of this study was to examine if this was possible using time difference imaging, in the anesthetised rat using 40 spring-loaded scalp electrodes with applied con...

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    authors: Dowrick T,Blochet C,Holder D

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  • Personalized automatic sleep staging with single-night data: a pilot study with Kullback-Leibler divergence regularization.

    abstract:OBJECTIVE:Brain waves vary between people. This work aims to improve automatic sleep staging for longitudinal sleep monitoring via personalization of algorithms based on individual characteristics extracted from sleep data recorded during the first night. APPROACH:As data from a single night are very small, thereby ma...

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    authors: Phan H,Mikkelsen K,Chén OY,Koch P,Mertins A,Kidmose P,De Vos M

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  • Effects of CO2 on dynamic cerebral autoregulation measurement.

    abstract::Arterial pCO2 is known to influence cerebral autoregulation but its effect on the dynamic relationship between mean arterial blood pressure (ABP) and mean cerebral blood flow velocity (CBFV), obtained from spontaneous fluctuations in ABP, has not been established. In 16 normal subjects, ABP was measured non-invasively...

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    authors: Panerai RB,Deverson ST,Mahony P,Hayes P,Evans DH

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  • A finite element model of needle electrode spatial sensitivity.

    abstract::We used the finite element (FE) method to estimate the spatial sensitivity of a needle electrode for bioimpedance measurements. This current conducting needle with an insulated shaft was inserted in a saline solution and the current was measured at the neutral electrode. Model resistance and reactance were calculated ...

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    authors: Høyum P,Kalvøy H,Martinsen ØG,Grimnes S

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  • Measurement of ventricular volume from blood conductance using two-dimensional finite element analysis.

    abstract::We used finite element analysis to study the relationship between the intraventricular blood conductance and the right ventricular volume. Previous studies reported a quasi-linear dependence between these two quantities. We quantified the effects of the resistivities of the surrounding tissues (e.g. heart wall, lungs)...

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    authors: Panescu D,Webster JG,Stratbucker RA

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    abstract::Automatic sleep stage classification with cardiorespiratory signals has attracted increasing attention. In contrast to the traditional manual scoring based on polysomnography, these signals can be measured using advanced unobtrusive techniques that are currently available, promising the application for personal and co...

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    authors: Fonseca P,Long X,Radha M,Haakma R,Aarts RM,Rolink J

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    pub_type: 杂志文章


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    abstract::A gamma fit facilitates smoothing and extrapolation of distorted tracer-dilution curves in blood flow studies. Theoretically based empirical estimators were developed as simple alternatives to direct regression approaches from simulated gamma distributions with a wide range of shape asymmetry. Key curve features of pe...

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    pub_type: 杂志文章


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