Abstract:
:Measurement of the velocity of propagation and attenuation of ultrasound (200 kHz) is believed to be a useful non-invasive technique for assessing the mechanical properties of bone. A new method for the determination of ultrasound velocity and attenuation of longitudinal waves in cortical bone was used in vivo and in situ on intact and fractured human tibiae. The measured ultrasound attenuation and velocity were found to be unaffected by the soft tissue between transducers and bone. The ultrasound velocity in vivo on control tibiae was 3614 +/- 32 m s-1 and the attenuation was 5.52 +/- 0.43 dB MHz-1 cm-1. The ultrasound velocity in fractured tibiae was considerably lower 1 week after fracture (2375 +/- 82 m s-1), but had significantly increased after 3 weeks (to 2882 +/- 90 m s-1). A higher attenuation was measured 1 week after fracture (17.81 +/- 3.91 dB MHz-1 cm-1), but it had decreased again 3 weeks after fracture (10.42 +/- 3.56 dB MHz-1 cm-1). In situ studies under well-defined conditions confirmed the in vivo results. The effects of internal plate fixation and gradually cutting through the cortex on the ultrasound velocity and attenuation were studied in situ. These results demonstrate the clinical potential of this technique for the non-invasive assessment of bone fracture healing.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Saulgozis J,Pontaga I,Lowet G,Van der Perre Gdoi
10.1088/0967-3334/17/3/006subject
Has Abstractpub_date
1996-08-01 00:00:00pages
201-11issue
3eissn
0967-3334issn
1361-6579journal_volume
17pub_type
临床试验,杂志文章abstract::Spirometry is the gold standard to determine the presence of airflow obstruction, but it requires volitional participation and needs qualified supervision. The forced oscillation technique (FOT) measures respiratory input impedance (Zrs) during spontaneous breathing and it could be useful for unsupervised monitoring o...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/31/4/N01
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVE:Transfer function analysis (TFA) of dynamic cerebral autoregulation (dCA) requires smoothing of spectral estimates using segmentation of the data (SD). Systematic studies are required to elucidate the potential influence of SD on dCA parameters. APPROACH:Healthy subjects (HS, n = 237) and acute ischaemic str...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab7ddf
更新日期:2020-04-17 00:00:00
abstract::We aim to investigate whether phase shift between respiratory oscillations in cerebral blood flow velocity (CBFV) and arterial blood pressure (ABP) is associated with changes in cerebral autoregulation (CA) or reflects the mechano-elastic properties of the cerebrovascular bed. The relationships between respiratory pha...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/38/2/310
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to explore the feasibility of titrating tidal volume (V T) and positive end-expiratory pressure (PEEP) during one-lung ventilation (OLV) based on ventilation distribution and oxygenation. APPROACH:Twenty-four consecutive patients requiring intubation with a double-lumen tube and subs...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaaeb2
更新日期:2018-03-29 00:00:00
abstract::We used finite element analysis to study the relationship between the intraventricular blood conductance and the right ventricular volume. Previous studies reported a quasi-linear dependence between these two quantities. We quantified the effects of the resistivities of the surrounding tissues (e.g. heart wall, lungs)...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/15/1/004
更新日期:1994-02-01 00:00:00
abstract::Temporal changes in the impedance spectra of bioelectrodes in contact with skin provide useful data for comparisons between differing electrode materials and skin preparation methods. Traditional impedance measuring systems employ swept frequency methods which will distort results in the impedance spectra of a sample ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/20/1/008
更新日期:1999-02-01 00:00:00
abstract::A major problem confronting application of impedance techniques to studies of disease is the extraction of intrinsic properties of the tissue from the measured impedances, which unavoidably involve geometric factors as well. Amongst the foremost are the sizes and locations of the measuring electrode arrays, and this p...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/34/11/1513
更新日期:2013-11-01 00:00:00
abstract::The standard electrocardiogram (ECG) is the most common non-invasive way to study atrial fibrillation (AF). In this respect, previous works have shown that the surface lead V(1) reflects mainly the dominant atrial frequency (DAF) of the right atrium (RA), which has been widely used to study AF. In a similar way, AF or...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/1/007
更新日期:2011-01-01 00:00:00
abstract::Objective assessment of stroke-patients' ability to control arm movements is vital for evidence-based therapy and progress monitoring. This study compares three different indices to quantify the quality of wrist movement during a task involving tracking a target on a screen. Each method is assessed in terms of agreeme...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/8/011
更新日期:2007-08-01 00:00:00
abstract::In this paper a description is given of the development, characterisation and first results of a thermal imaging device aimed at significantly reducing the incidence of diabetic foot ulceration (DFU). These devices will be used in three clinical centres and in two preliminary clinical trials. The first will be on heal...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aa56b1
更新日期:2017-03-01 00:00:00
abstract::The outflow conductance (C(out)) of the cerebrospinal fluid (CSF) system is a parameter considered to be predictive in selection for hydrocephalus surgery. C(out) can be determined through an infusion test. A new apparatus for performing infusion tests in a standardized and automated way was developed. The objective w...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/6/022
更新日期:2005-12-01 00:00:00
abstract::The specific heat capacity of tissue is a critical parameter for thermal therapies that act over a long period of time. It is also critical for thermoacoustic signal generation. We present ex vivo measurements of specific heat capacity performed by a dual-pin probe with tight temperature control of the specimen. One 3...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/11/N02
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:Brain waves vary between people. This work aims to improve automatic sleep staging for longitudinal sleep monitoring via personalization of algorithms based on individual characteristics extracted from sleep data recorded during the first night. APPROACH:As data from a single night are very small, thereby ma...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab921e
更新日期:2020-07-01 00:00:00
abstract::A new algorithm for classifying ECG recording quality based on the detection of commonly observed ECG contaminants which often render the ECG unusable for diagnostic purposes was evaluated. Contaminants (baseline drift, flat line, QRS-artefact, spurious spikes, amplitude stepwise changes, noise) were detected on indiv...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/33/9/1435
更新日期:2012-09-01 00:00:00
abstract::Arterial pCO2 is known to influence cerebral autoregulation but its effect on the dynamic relationship between mean arterial blood pressure (ABP) and mean cerebral blood flow velocity (CBFV), obtained from spontaneous fluctuations in ABP, has not been established. In 16 normal subjects, ABP was measured non-invasively...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/20/3/304
更新日期:1999-08-01 00:00:00
abstract::Polysomnography (PSG) has been extensively studied for sleep staging, where sleep stages are usually classified as wake, rapid-eye-movement (REM) sleep, or non-REM (NREM) sleep (including light and deep sleep). Respiratory information has been proven to correlate with autonomic nervous activity that is related to slee...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/12/2529
更新日期:2014-12-01 00:00:00
abstract::There are currently no objective means of quantifying chest wall vibrations during manual physiotherapy. The aims of the study were to (i) develop a method to quantify physiotherapy-applied forces and simultaneous changes in respiratory flow and pressure, (ii) assess the feasibility of using this method in ventilated ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/9/004
更新日期:2007-09-01 00:00:00
abstract::Vital signs monitoring is ubiquitous in clinical environments and emerging in home-based healthcare applications. Still, since current monitoring methods require uncomfortable sensors, respiration rate remains the least measured vital sign. In this paper, we propose a video-based respiration monitoring method that aut...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/1/100
更新日期:2016-01-01 00:00:00
abstract::Sedentary behaviour (SB) is associated with a number of adverse health outcomes. Studies that have used ActiGraph monitors to define sedentary time tend to use a threshold of <100 counts per minute (cpm) for classifying SB; however, this cut-point was not empirically derived for adults. It is not known whether ActiGr...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/10/1669
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:Evoked tympanic membrane displacement (TMD) is a non-invasive technique for assessing intracranial pressure (ICP). The aim of this study was to define reference intervals (RIs) in the healthy population. APPROACH:Measurements were made in 154 healthy adults. Results were quantified by V m, which is the most ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaa1d3
更新日期:2018-01-31 00:00:00
abstract::The measurement of the complex respiratory impedance at a high temporal resolution is described. The measurement of impedance is correlated with the breathing cycle using electrical transthoracic impedance. This allows the determination of the complex impedance at any fixed point in the respiratory cycle, which result...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/14/3/019
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVE:To investigate if modern seismocardiography (SCG) and ballistocardiography (BCG) are useful in the detection of hemodynamic changes occurring during simulated obstructive apneic events. METHODS:Forty-seven healthy volunteers performed a voluntary maximum Mueller maneuver (MM) for 10 s, and SCG and BCG signal...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab924b
更新日期:2020-07-09 00:00:00
abstract:OBJECTIVE:Cognitive reserve (CR) refers to the capacity of the brain to actively cope with damage via the implementation of remedial cognitive processes. Traditional CR measurements focus on static proxies, which may not be able to appropriately estimate dynamic changes in CR. This study therefore investigated the cogn...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab979e
更新日期:2020-07-07 00:00:00
abstract::We present a method for location of fetal QRS in maternal abdominal ECG recordings. This method's initial, global approach was proposed in the context of the 2013 PhysioNet/Computing in Cardiology Challenge where it was tested on the 447 four channel one-minute recordings.The first step is filtering to eliminate basel...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/8/1699
更新日期:2014-08-01 00:00:00
abstract::Patients with claudication have an inadequate haemodynamic response to exercise. Blood flow response will not only have a magnitude, but also a rate of change. There is scope for investigating these parameters, as manipulation of the factors which control them may benefit work to improve the treatment for claudication...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/26/6/002
更新日期:2005-12-01 00:00:00
abstract::A nonlinear model predictive controller has been developed to maintain normoglycemia in subjects with type 1 diabetes during fasting conditions such as during overnight fast. The controller employs a compartment model, which represents the glucoregulatory system and includes submodels representing absorption of subcut...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/25/4/010
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:An artefact-free electrocardiogram (ECG) is essential during cardiac arrest to decide therapy such as defibrillation. Mechanical cardiopulmonary resuscitation (CPR) devices cause movement artefacts that alter the ECG. This study analyzes the effectiveness of mechanical CPR artefact suppression filters to rest...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab9e53
更新日期:2020-11-06 00:00:00
abstract::The assessment and diagnosis of lower limb peripheral arterial occlusive disease (PAOD) is important since it can lead progressively to disabling claudication, ischaemic rest pain and gangrene. Historically, the first assessment has been palpation of the peripheral pulse since it can become damped, delayed and diminis...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/5/018
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:This paper aims to present how physiological signals can be processed based on wavelet decomposition to calculate multiple physiological parameters in real-time on an embedded platform. APPROACH:An ECG and PPG are decomposed to the appropriate scale based on a quadratic spline wavelet base in order to obtain...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab6f52
更新日期:2020-03-06 00:00:00
abstract::The purpose of this study was to examine the performance of dual-energy computed tomography (DECT) for the quantification of liver fat content (LFC). We prepared two phantoms: homogenized mixtures of porcine liver and fat and homogeneous mixtures of liver- and fat-equivalent solutions. Tubes containing mixtures with k...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/4/597
更新日期:2014-04-01 00:00:00