Abstract:
:Electrical impedance is one of the most often used parameters for characterizing material properties, especially in biomedical applications. Electrical impedance spectroscopy (EIS), used for revealing both resistive and capacitive characteristics, is good for use in tissue characterization. In this study, a portable and simple EIS system based on a commercially available chip was used to assess rat intestinal tissues following irradiation. The EIS results were fitted to a resistor and capacitor electrical circuit model to solve the electrical properties of the tissue. The variation in the tissue's electrical characteristics was compared to the morphological and histological findings. From the experimental results, it was clear that the electrical properties, based on receiver operation curve analysis, demonstrated good detection performance relative to the histological changes. The electrical parameters of the tissues could be used to distinguish the tissue's status for investigation, which introduced a concept of 'electrical biopsy', and this 'electrical biopsy' approach may be used to complement histological examinations.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Huang YJ,Huang EY,Lu YY,Chen CY,Cheng KSdoi
10.1088/0967-3334/32/9/010subject
Has Abstractpub_date
2011-09-01 00:00:00pages
1491-504issue
9eissn
0967-3334issn
1361-6579pii
S0967-3334(11)88301-2journal_volume
32pub_type
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