Abstract:
:Spirometry is the gold standard to determine the presence of airflow obstruction, but it requires volitional participation and needs qualified supervision. The forced oscillation technique (FOT) measures respiratory input impedance (Zrs) during spontaneous breathing and it could be useful for unsupervised monitoring of airway obstruction. We developed a FOT device for home monitoring of Zrs which transmits the data through the Internet. Its accuracy, stability and reliability were evaluated in a pilot study measuring the Zrs in the unsupervised self-measurements of five healthy subjects. Finally, to explore the applicability of the concept, 36 consecutive daily home measurements were recorded from one healthy subject and one chronic obstructive pulmonary disease (COPD) patient. The accuracy of the device fulfilled FOT guidelines, and the reliability test showed a mean discrepancy of resistance of 0.10 +/- 0.01 cmH(2)O s L(-1). The data from the healthy subjects demonstrated high repeatability in assessing Zrs. The measurements on the healthy subjects and the patient with COPD suggest the feasibility of unsupervised FOT measurements. The healthy subjects showed minimal daily variations in Zrs, whereas the patient with COPD had large differences in mean values and important fluctuations over day-to-day measurements. The results of the pilot study demonstrate that unsupervised home monitoring of Zrs using the FOT yields accurate and reproducible data. It could provide new insights into the dynamics of airway obstruction and improve the understanding and management of obstructive diseases.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Dellacà RL,Gobbi A,Pastena M,Pedotti A,Celli Bdoi
10.1088/0967-3334/31/4/N01subject
Has Abstractpub_date
2010-04-01 00:00:00pages
N11-24issue
4eissn
0967-3334issn
1361-6579pii
S0967-3334(10)33232-3journal_volume
31pub_type
杂志文章abstract::Temporal changes in the impedance spectra of bioelectrodes in contact with skin provide useful data for comparisons between differing electrode materials and skin preparation methods. Traditional impedance measuring systems employ swept frequency methods which will distort results in the impedance spectra of a sample ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/20/1/008
更新日期:1999-02-01 00:00:00
abstract::Although cardiac arrhythmias have been studied extensively, little is known about arrhythmic phenomena in the gastrointestinal (GI) system. In this study, we demonstrate for the first time that the onset of GI arrhythmias is associated with statistically significant fluctuations in the information dimension of the ass...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/5/N01
更新日期:2008-05-01 00:00:00
abstract::The electrocardiogram is a representative signal containing information about the condition of the heart. The shape and size of the P-QRS-T wave, the time intervals between its various peaks, etc may contain useful information about the nature of disease affecting the heart. However, the human observer cannot directly...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/25/5/005
更新日期:2004-10-01 00:00:00
abstract::False intensive care unit (ICU) alarms induce stress in both patients and clinical staff and decrease the quality of care, thus significantly increasing both the hospital recovery time and rehospitalization rates. In the PhysioNet/CinC Challenge 2015 for reducing false arrhythmia alarms in ICU bedside monitor data, th...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/8/1273
更新日期:2016-08-01 00:00:00
abstract::Non-invasive in vivo neutron activation analysis (NAA) was used to measure the fluorine concentration in 35 people in Hamilton, Ontario, Canada. Measurement and precision data of this second generation NAA system were determined in 2013, and the results were compared with the performance of a first generation system u...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/3/465
更新日期:2015-03-01 00:00:00
abstract::Previous studies have proved that the baroreceptor reflex (baroreflex) control of heart rate can be used for stratification of post-infarction population and, in general, cardiovascular disease populations. Many methods have been proposed to estimate the so-called baroreflex sensitivity (BRS) expressed as ms mmhg-1. M...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/38/1/63
更新日期:2017-01-01 00:00:00
abstract::Capnography is a continuous and noninvasive method for carbon dioxide (CO2) measurement, and it has become the standard of care for basic respiratory monitoring for intubated patients in the intensive care unit. In addition, it has been used to adjust ventilatory parameters during mechanical ventilation (MV). However,...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/2/231
更新日期:2015-02-01 00:00:00
abstract::Gated SPECT (GSPECT) was evaluated for the measurement of left ventricular ejection fraction (LVEF) by comparing with equilibrium gated radionuclide ventriculography (RNVG). A total of 99 subjects underwent GSPECT and RNVG imaging. All studies were acquired in list mode with GSPECT studies processed to give 16- and 8-...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/22/2/312
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:Accurate bladder size estimation is an important clinical parameter that assists physicians, enabling them to provide better treatment for patients who are suffering from urinary incontinence. Electrical impedance tomography (EIT) is a non-invasive medical imaging method that estimates organ boundaries assumi...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abaa56
更新日期:2020-12-18 00:00:00
abstract:OBJECTIVE:Plots of blood volume measurements over time (profiles) may identify euvolemia during fluid removal for acute heart failure. We assessed agreement between two noninvasive measurements of blood volume profiles during mechanical fluid removal, which exemplifies the interstitial fluid shifts that occur during di...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab21af
更新日期:2019-07-01 00:00:00
abstract::Peripheral vasculature disease is strongly correlated with cardiovascular-associated mortality. Monitoring circulation health, especially in the peripheral limbs, is vital to detecting clinically significant disease at a stage when it can still be addressed through medical intervention. Electrical impedance tomography...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/3/006
更新日期:2008-03-01 00:00:00
abstract::Automatic sleep stage classification with cardiorespiratory signals has attracted increasing attention. In contrast to the traditional manual scoring based on polysomnography, these signals can be measured using advanced unobtrusive techniques that are currently available, promising the application for personal and co...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/10/2027
更新日期:2015-10-01 00:00:00
abstract::In this study, the selection of coil configuration parameters (coil radius and coil centre shift) for induced current EIT using circular coils is investigated. An alternative coil configuration is suggested, which produces approximately linear (spatially) magnetic fields in order to strengthen the currents in the cent...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/15/2a/007
更新日期:1994-05-01 00:00:00
abstract::The purpose of this study was to determine the validity and reliability of a timed 5 km cycle ergometer ride to predict maximum oxygen uptake (VO2max). Fifty-two healthy volunteers had their VO2max determined during a maximal treadmill run. They also performed a timed 5 km cycle ergometer ride. The resistance setting ...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1088/0967-3334/17/4/009
更新日期:1996-11-01 00:00:00
abstract::A simple wearable device for sit-to-stand timing detection was designed and constructed with rate gyroscopes and accelerometers and a dedicated adaptive algorithm. The method was validated by comparison with optoelectronic equipment. Results from the comparison showed a maximal error always lower than 2.5 x 10(-2) s f...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/8/006
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVE:This paper aims to report on the accuracy of estimating sleep stages using a wrist-worn device that measures movement using a 3D accelerometer and an optical pulse photoplethysmograph (PPG). APPROACH:Overnight recordings were obtained from 60 adult participants wearing these devices on their left and right w...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aa9047
更新日期:2017-10-31 00:00:00
abstract::We used finite element analysis to study the relationship between the intraventricular blood conductance and the right ventricular volume. Previous studies reported a quasi-linear dependence between these two quantities. We quantified the effects of the resistivities of the surrounding tissues (e.g. heart wall, lungs)...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/15/1/004
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:In this study, electroencephalography activity recorded during monotonous driving was investigated to examine the predictive capability of monopolar EEG analysis for fatigue/sleepiness in a cohort of train drivers. APPROACH:Sixty-three train drivers participated in the study, where 32- lead monopolar EEG dat...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aae42e
更新日期:2018-10-30 00:00:00
abstract::Body temperature measurement is an important clinical parameter. The performance of a number of non-invasive thermometers was measured by comparing intra- and inter-operator variability (n = 100) and clinical accuracy (n = 61). Variability was elevated in febrile compared to normothermic subjects for axillary and oral...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/31/9/003
更新日期:2010-09-01 00:00:00
abstract::Energy scavenging has increasingly become an interesting option for powering electronic devices because of the almost infinite lifetime and the non-dependence on fuels for energy generation. Moreover, the rise of wireless technologies promises new applications in medical monitoring systems, but these still face limita...
journal_title:Physiological measurement
pub_type: 杂志文章,评审
doi:10.1088/0967-3334/30/9/R01
更新日期:2009-09-01 00:00:00
abstract::Neuromagnetic recordings were used to check if electrical stimulation of the auditory nerve in cochlear-implant patients activates cortical auditory areas in a similar manner as acoustic stimulation in normal hearing subjects or whether the excitation processes are different. The waveform of the evoked magnetic field ...
journal_title:Physiological measurement
pub_type: 杂志文章,评审
doi:10.1088/0967-3334/14/4a/014
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:As the global burden of cardiovascular disease increases, proactive cardiovascular healthcare by means of accurate, precise, continuous, and non-invasive monitoring is becoming crucial. However, no current device is able to provide cardiac hemodynamic monitoring with the aforementioned criterion. Electrical i...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abb141
更新日期:2020-10-06 00:00:00
abstract::Electrical impedance tomography (EIT) could be significantly advantageous to continuous monitoring of lung development in newborn and, in particular, preterm infants as it is non-invasive and safe to use within the intensive care unit. It has been demonstrated that accurate boundary form of the forward model is import...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/6/1149
更新日期:2014-06-01 00:00:00
abstract::In this paper we present the concept, the design and the test procedure for a DSP-based high-precision and high-performance wide-band (up to 10 MHz) bioimpedance analyser module for application in EIT or bioimpedance spectroscopy. The module implements a digital concept with appropriate signal conditioning hardware fo...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/22/1/303
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:Video and sound acquisition and processing technologies have seen great improvements in recent decades, with many applications in the biomedical area. The aim of this paper is to review the overall state of the art of advances within these topics in paediatrics and to evaluate their potential application for ...
journal_title:Physiological measurement
pub_type: 杂志文章,评审
doi:10.1088/1361-6579/ab0096
更新日期:2019-02-26 00:00:00
abstract::High-frequency (HF) oscillations in RR interval from 0.15-0.40 Hz are widely accepted as a measure of cardiac vagal outflow but the HF/RR relationship appears complex, particularly with longer RR intervals. The aim of this study was to evaluate the HF/RR interval relationship during free and paced breathing. HF power ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/7/008
更新日期:2008-07-01 00:00:00
abstract::False alarm (FA) rates as high as 86% have been reported in intensive care unit monitors. High FA rates decrease quality of care by slowing staff response times while increasing patient burdens and stresses. In this study, we proposed a rule-based and multi-channel information fusion method for accurately classifying ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/8/1298
更新日期:2016-08-01 00:00:00
abstract::We have developed an eight-channel telemetry system for studying experimental models of chronic cardiovascular disease. The system is an extension of a previous device that has been miniaturized, reduced in power consumption and provided with increased functionality. We added sensors for ventricular dimension, and cor...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/3/002
更新日期:2007-03-01 00:00:00
abstract::Monitoring the brain state in anaesthesia is crucial for clinical doctors. In this study, we propose a novel nonlinear method, the permutation Lempel-Ziv complexity (PLZC) index, which describes the complexity in the electroencephalographic (EEG) signal to quantify the effect of GABAergic anaesthetics on brain activit...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/12/2483
更新日期:2015-12-01 00:00:00
abstract::Gastro-oesophageal pH measurements are routinely carried out to quantify and determine if levels of acid reflux are responsible for symptoms. Although considered the 'gold standard', evidence suggests that pH measurements do not correlate well with the degree of oesophagitis seen during endoscopy. In this study the cu...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/24/4/006
更新日期:2003-11-01 00:00:00