Abstract:
:Fetal hiccups emerge as early as nine weeks post-conception, being the predominant diaphragmatic movement before 26 weeks of gestation. They are considered as a programmed isometric inspiratory muscle exercise of the fetus in preparation for the post-natal respiratory function, or a manifestation of a reflex circuitry underlying the development of suckling and gasping patterns. The present paper provides the first evidence of non-invasive biomagnetic measurements of the diaphragm spasmodic contractions associated with fetal hiccups. The magnetic field patterns generated by fetal hiccups exhibit well-defined morphological features, consisting of an initial high frequency transient waveform followed by a more prolonged low frequency component. This pattern is consistent across recordings obtained from two fetal subjects, and it is confirmed by signals recorded in a neonatal subject. These results demonstrate that fetal biomagnetometry can provide insights into the electrophysiological mechanisms of diaphragm motor function in the fetus. Additionally, we study the correlation between hiccup events and fetal cardiac rhythm and provide evidence that hiccups may modulate the fetal heart rate during the last trimester of pregnancy.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Popescu EA,Popescu M,Bennett TL,Lewine JD,Drake WB,Gustafson KMdoi
10.1088/0967-3334/28/6/005subject
Has Abstractpub_date
2007-06-01 00:00:00pages
665-76issue
6eissn
0967-3334issn
1361-6579pii
S0967-3334(07)45602-7journal_volume
28pub_type
杂志文章abstract::The objective of this study was to adapt a novel near-infrared diffuse correlation spectroscopy (DCS) flow-oximeter for simultaneous and continuous monitoring of relative changes in cerebral blood flow (rCBF) and cerebral oxygenation (i.e. oxygenated/deoxygenated/total hemoglobin concentration: Δ[HbO2]/Δ[Hb]/ΔTHC) dur...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/10/2135
更新日期:2014-10-01 00:00:00
abstract::Balance is the ability to maintain equilibrium while sitting or standing. There are a number of different methods which are used to assess balance: technical methods such as sway magnetometry, ataxia meter and force platforms, and clinical methods such as the functional reach test, Berg balance test and fall risk inde...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/21/4/309
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:Accurate bladder size estimation is an important clinical parameter that assists physicians, enabling them to provide better treatment for patients who are suffering from urinary incontinence. Electrical impedance tomography (EIT) is a non-invasive medical imaging method that estimates organ boundaries assumi...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abaa56
更新日期:2020-12-18 00:00:00
abstract::Long-term electrocardiography (ECG) featuring adequate atrial and ventricular signal quality is highly desirable. Routinely used surface leads are limited in atrial signal sensitivity and recording capability impeding complete ECG delineation, i.e. in the presence of supraventricular arrhythmias. Long-term esophageal ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/4/517
更新日期:2014-04-01 00:00:00
abstract::The aim of this study was to analyse the feasibility of long-term measurements of cerebral (crSO2) and peripheral (prSO2) regional tissue oxygen saturation on the first day of life by determining the amount of artefacts and their influence on rSO2. Near infrared spectroscopy (NIRS) measurements were performed fronto-p...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/7/1349
更新日期:2014-07-01 00:00:00
abstract::This observational study investigated digital auscultation for the purpose of assessing the clinical feasibility of monitoring vascular sounds in pregnancy. The study was performed at the Regional Hospital Viborg, Denmark, and included 29 pregnant women, 10 non-pregnant women and 10 male participants. Digital ausculta...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/7/1163
更新日期:2016-07-01 00:00:00
abstract::An accurate reproducible measurement of left ventricular volume is important in the evaluation of cardiac disease. Four methods of left ventricular volume measurement by radionuclide ventriculography have been compared and their reproducibility assessed in a patient group. The methods studied were a geometric method, ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/14/1/004
更新日期:1993-02-01 00:00:00
abstract::The paper describes the development of an electrical impedance tomography (EIT) system for gynecologic research. The GIT (gynecological impedance tomography) system has 48 electrodes and is embedded on a small space (30 mm diameter and 20 mm height) inside of the vaginal probe. The system provides real-time (one shot ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/33/5/849
更新日期:2012-05-01 00:00:00
abstract::Cardiac output (CO) monitoring is not only essential for critically ill patients in the hospital, but also for patients at home and those undergoing cardiopulmonary exercise testing. However, CO is difficult to monitor during daily activities and exercise. In this paper, we aim at developing a novel CO estimation meth...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/31/5/008
更新日期:2010-05-01 00:00:00
abstract::Twenty-nine patients were monitored overnight for breathing distress patterns during postoperative analgesia. Nasal flow apnoea monitoring and pulse oximetry data were recorded at 50 Hz. Respiratory inductive plethysmography (RIP) tracked tidal volume (TV) thoracoabdominal motion, and supplemented the flow monitoring ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/20/2/307
更新日期:1999-05-01 00:00:00
abstract::The pre-ejection period (PEP) has recently been described as a potential parameter for monitoring cardiac preload. This study further investigated the influence of changes in intravascular volume status and the application of positive end-expiratory pressure (PEEP) on the pre-ejection period. In ten pigs, ECG, arteria...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/26/6/012
更新日期:2005-12-01 00:00:00
abstract::Energy scavenging has increasingly become an interesting option for powering electronic devices because of the almost infinite lifetime and the non-dependence on fuels for energy generation. Moreover, the rise of wireless technologies promises new applications in medical monitoring systems, but these still face limita...
journal_title:Physiological measurement
pub_type: 杂志文章,评审
doi:10.1088/0967-3334/30/9/R01
更新日期:2009-09-01 00:00:00
abstract::Thermal sweating manikins are used to analyse the heat and mass transfer phenomena in the skin-clothing-environment system. However, the limiting factor of present thermal manikins is their inability to simulate adequately the human thermal behaviour, which has a significant effect on the clothing microenvironment. A ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/2/002
更新日期:2008-02-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to monitor the physiological changes and cytotoxic effects of exogenous contrast agents during photoacoustic imaging (PAI) and photothermal therapy (PTT). In this paper, a low-power telemetric device for mouse vital signs monitoring was designed and demonstrated. APPROACH:The power ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aba6a1
更新日期:2021-01-01 00:00:00
abstract::There is a lack of studies that examine the dynamics of heat-induced shrinkage of organ tissues. Clinical procedures such as radiofrequency ablation, microwave ablation or high-intensity focused ultrasound, use heat to treat diseases such as cancer and cardiac arrhythmia. When heat is applied to tissues, shrinkage occ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/1/55
更新日期:2014-01-01 00:00:00
abstract::Previous studies demonstrate that it is possible to evaluate a heart graft rejection condition using a bioimpedance technique by means of an intracavitary catheter. We propose to use a less invasive technique consisting in the use of a transoesophageal catheter and two standard ECG electrodes on the thorax. The aim of...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/7/S10
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:Currently, continuous blood pressure (BP) measurements are mostly based on multi-sensor combinations and datasets with limited BP ranges. Besides, most BP-related features derive from the photoplethysmogram (PPG) signal. The mechanism of PPG signal formation is not considered. We aimed to design a noninvasive...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abc8dd
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Physical activity has been shown to impact future health outcomes in adults, but little is known about the long-term impact of physical activity in toddlers. Accurately measuring the specific types and amounts of physical activity in toddlers will help us to understand, predict, and better affect their future...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab6ebb
更新日期:2020-03-06 00:00:00
abstract:OBJECTIVE:Non-contact physiological measurement is a growing research area that allows capturing vital signs such as heart rate (HR) and breathing rate (BR) comfortably and unobtrusively with remote devices. However, most of the approaches work only in bright environments in which subtle photoplethysmographic and balli...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aae625
更新日期:2018-10-30 00:00:00
abstract::Capillary refill time (CRT) is a simple means of cardiovascular assessment which is widely used in clinical care. Currently, CRT is measured through manual assessment of the time taken for skin tone to return to normal colour following blanching of the skin surface. There is evidence to suggest that manually assessed ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/1/83
更新日期:2016-01-01 00:00:00
abstract::Infant multiple breath washout (MBW) testing serves as a primary outcome in clinical studies. However, it is still unknown whether current software algorithms allow between-centre comparisons. In this study of healthy infants, we quantified MBW measurement errors and tried to improve data quality by simply changing so...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/37/3/L1
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:Brain-computer interfaces (BCIs) are aimed at providing a new way of communication between the human brain and external devices. One of the major tasks associated with the BCI system is to improve classification performance of the motor imagery (MI) signal. Electroencephalogram (EEG) signals are widely used f...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aba07b
更新日期:2020-08-11 00:00:00
abstract::The results of a preliminary clinical evaluation of a one-frequency electrical impedance tomography (EIT) system enabling static in vivo imaging are presented. The design of the measuring system and image reconstruction software are described. Thirty-one subjects were examined and divided into four clinical groups. Th...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/23/1/304
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVE:Tensiomyography (TMG) and myotonometry (MMT) are two novel technologies that measure neuromuscular properties. These two devices measure the stiffness of the soft tissue as well as other variables. The aim of this study is to analyze if there is any correlation between maximal radial displacement (Dm) and Sti...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/abcdf4
更新日期:2020-12-31 00:00:00
abstract::The aim of this study was to investigate masticatory muscle activity during deliberately performed functional and non-functional oral tasks. Electromyographic (EMG) surface activity was recorded unilaterally from the masseter, anterior temporalis and suprahyoid muscles in 11 subjects (5 men, 6 women; age = 34.6 +/- 10...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/12/004
更新日期:2008-12-01 00:00:00
abstract::The postural stability of 30 normal subjects in the age range 15 to 64 years was measured on five separate occasions, using the sway magnetometry technique, to determine the day-to-day repeatability of this measurement technique. On each occasion the pathlength and area enclosed by movement of the hips in a horizontal...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/19/2/003
更新日期:1998-05-01 00:00:00
abstract::Body temperature measurement is an important clinical parameter. The performance of a number of non-invasive thermometers was measured by comparing intra- and inter-operator variability (n = 100) and clinical accuracy (n = 61). Variability was elevated in febrile compared to normothermic subjects for axillary and oral...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/31/9/003
更新日期:2010-09-01 00:00:00
abstract::The goal of the present study was to develop and evaluate a new method for the prediction of unexplained syncope occurrences. Diagnosis of syncope is currently based on the reproduction of symptoms in combination with hypotension and bradycardia induced by a 45 min 60-70 degrees head-upright tilt test (HUTT). The main...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/28/2/007
更新日期:2007-02-01 00:00:00
abstract::Measurement of the velocity of propagation and attenuation of ultrasound (200 kHz) is believed to be a useful non-invasive technique for assessing the mechanical properties of bone. A new method for the determination of ultrasound velocity and attenuation of longitudinal waves in cortical bone was used in vivo and in ...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/17/3/006
更新日期:1996-08-01 00:00:00
abstract::High-frequency (HF) oscillations in RR interval from 0.15-0.40 Hz are widely accepted as a measure of cardiac vagal outflow but the HF/RR relationship appears complex, particularly with longer RR intervals. The aim of this study was to evaluate the HF/RR interval relationship during free and paced breathing. HF power ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/7/008
更新日期:2008-07-01 00:00:00