Abstract:
OBJECTIVE:It is accepted that changes in the peripheral pulse waveform characteristics occur with ageing. Pulse risetime is one important feature which has clinical value. However, it is unclear how it varies across the full age spectrum from child to senior and for different peripheral measurement sites. The objectives of this study were to determine the association between age and pulse risetime characteristics over an 8-decade age range at the ears, fingers, and toes, and to consider effects arising from differences in systolic blood pressure (SBP), height and heart rate. APPROACH:Multi-site photoplethysmography (MPPG) pulse waveforms were recorded non-invasively from the right and left ears, fingers, and toes of 304 normal healthy human subjects (range 6-87 years; 156 male and 148 female). SBP, height, and heart rate were also measured. Multi-site PPG pulse risetimes, and their site differences, were determined. MAIN RESULTS:Univariate regression analysis showed positive correlations with risetime for age (ears, fingers and toes: + 0.8, + 1.9, and + 1.1 ms/year, respectively), SBP (+0.5, + 1.3, and + 0.9 ms/mmHg) and height (+0.5, + 1.2, and + 1.0 ms/cm), but with a clear inverse association with heart rate (-1.8, - 2.5, and - 1.6 ms min) (P < 0.0001). No significant differences between male and female subjects were found for pulse risetime. SIGNIFICANCE:Normative multi-site PPG risetime characteristics have been defined in over 300 subjects and are shown to increase with age linearly up to the 8th decade. In contrast, we have shown that heart rate has a clear inverse relationship with risetime for all measurement sites.
journal_name
Physiol Measjournal_title
Physiological measurementauthors
Allen J,O'Sullivan J,Stansby G,Murray Adoi
10.1088/1361-6579/ab9b67subject
Has Abstractpub_date
2020-08-11 00:00:00pages
074001issue
7eissn
0967-3334issn
1361-6579journal_volume
41pub_type
杂志文章abstract::A nonlinear model predictive controller has been developed to maintain normoglycemia in subjects with type 1 diabetes during fasting conditions such as during overnight fast. The controller employs a compartment model, which represents the glucoregulatory system and includes submodels representing absorption of subcut...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/25/4/010
更新日期:2004-08-01 00:00:00
abstract::The purpose of this study was to examine the performance of dual-energy computed tomography (DECT) for the quantification of liver fat content (LFC). We prepared two phantoms: homogenized mixtures of porcine liver and fat and homogeneous mixtures of liver- and fat-equivalent solutions. Tubes containing mixtures with k...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/4/597
更新日期:2014-04-01 00:00:00
abstract::Non-invasive in vivo neutron activation analysis (NAA) was used to measure the fluorine concentration in 35 people in Hamilton, Ontario, Canada. Measurement and precision data of this second generation NAA system were determined in 2013, and the results were compared with the performance of a first generation system u...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/3/465
更新日期:2015-03-01 00:00:00
abstract:OBJECTIVE:An artefact-free electrocardiogram (ECG) is essential during cardiac arrest to decide therapy such as defibrillation. Mechanical cardiopulmonary resuscitation (CPR) devices cause movement artefacts that alter the ECG. This study analyzes the effectiveness of mechanical CPR artefact suppression filters to rest...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab9e53
更新日期:2020-11-06 00:00:00
abstract:OBJECTIVE:Plots of blood volume measurements over time (profiles) may identify euvolemia during fluid removal for acute heart failure. We assessed agreement between two noninvasive measurements of blood volume profiles during mechanical fluid removal, which exemplifies the interstitial fluid shifts that occur during di...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab21af
更新日期:2019-07-01 00:00:00
abstract::Although people spend a third of their day engaged in sedentary activities, research on heart activity during sitting is almost nonexistent because of the discomfort experienced when electrocardiogram (ECG) measurement electrodes are attached to the body. Accordingly, in this study, a system was developed to monitor h...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/3/N61
更新日期:2015-03-01 00:00:00
abstract::A new image reconstruction algorithm is proposed to visualize static conductivity images of a subject in magnetic resonance electrical impedance tomography (MREIT). Injecting electrical current into the subject through surface electrodes, we can measure the induced internal magnetic flux density B = (Bx, By, Bz) using...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/25/1/030
更新日期:2004-02-01 00:00:00
abstract::Measurement of the velocity of propagation and attenuation of ultrasound (200 kHz) is believed to be a useful non-invasive technique for assessing the mechanical properties of bone. A new method for the determination of ultrasound velocity and attenuation of longitudinal waves in cortical bone was used in vivo and in ...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/17/3/006
更新日期:1996-08-01 00:00:00
abstract::A photoacoustic technique is used for studying topically applied substance absorption in human skin. The proposed method utilizes a double-chamber PA cell. The absorption determination was obtained through the measurement of the thermal effusivity of the binary system substance-skin. The theoretical model assumes that...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/23/3/304
更新日期:2002-08-01 00:00:00
abstract::Previous studies demonstrate that it is possible to evaluate a heart graft rejection condition using a bioimpedance technique by means of an intracavitary catheter. We propose to use a less invasive technique consisting in the use of a transoesophageal catheter and two standard ECG electrodes on the thorax. The aim of...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/7/S10
更新日期:2011-07-01 00:00:00
abstract::The measurement of the complex respiratory impedance at a high temporal resolution is described. The measurement of impedance is correlated with the breathing cycle using electrical transthoracic impedance. This allows the determination of the complex impedance at any fixed point in the respiratory cycle, which result...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/14/3/019
更新日期:1993-08-01 00:00:00
abstract::A study of the concentrations of the common breath metabolites ammonia, acetone, isoprene, ethanol and acetaldehyde in the breath of five subjects over a period of 30 days has been carried out. Breath samples were taken and analysed in the early morning on arrival at the laboratory. The real time analyses of three con...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/24/1/308
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:Using raw, sub-second-level accelerometry data, we propose and validate a method for identifying and characterizing walking in the free-living environment. We focus on sustained harmonic walking (SHW), which we define as walking for at least 10 s with low variability of step frequency. APPROACH:We utilize th...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/aaa74d
更新日期:2018-02-28 00:00:00
abstract::Multiple frequency bio-electrical impedance analysis (MFBIA) may be useful for monitoring fluid balance in newborn infants or to provide early prediction of the outcome following perinatal asphyxia. A reference range of data is needed for identification of babies with abnormal impedance values. This was a cross-sectio...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/27/11/010
更新日期:2006-11-01 00:00:00
abstract::Cooperative sensors is a novel measurement architecture that allows the acquiring of biopotential signals on patients in a comfortable and easy-to-integrate manner. The novel sensors are defined as cooperative in the sense that at least two of them work in concert to measure a target physiological signal, such as a mu...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/4/767
更新日期:2015-04-01 00:00:00
abstract::A new algorithm for classifying ECG recording quality based on the detection of commonly observed ECG contaminants which often render the ECG unusable for diagnostic purposes was evaluated. Contaminants (baseline drift, flat line, QRS-artefact, spurious spikes, amplitude stepwise changes, noise) were detected on indiv...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/33/9/1435
更新日期:2012-09-01 00:00:00
abstract::Electrical impedance tomography (EIT) is expected to become a valuable tool for monitoring mechanically ventilated patients due to its ability to continuously assess regional lung ventilation and aeration. Several sources of interference with EIT examinations exist in intensive care units (ICU). Our objectives are to ...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/32/12/F01
更新日期:2011-12-01 00:00:00
abstract::Idiopathic normal pressure hydrocephalus (INPH) patients have a disturbance in the dynamics of the cerebrospinal fluid (CSF) system. The outflow conductance, C, of the CSF system has been suggested to be prognostic for positive outcome after treatment with a CSF shunt. All current methods for estimation of C have draw...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/11/003
更新日期:2007-11-01 00:00:00
abstract::We present a method for location of fetal QRS in maternal abdominal ECG recordings. This method's initial, global approach was proposed in the context of the 2013 PhysioNet/Computing in Cardiology Challenge where it was tested on the 447 four channel one-minute recordings.The first step is filtering to eliminate basel...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/8/1699
更新日期:2014-08-01 00:00:00
abstract::Non-contact vital sign monitoring enables the estimation of vital signs, such as heart rate, respiratory rate and oxygen saturation (SpO2), by measuring subtle color changes on the skin surface using a video camera. For patients in a hospital ward, the main challenges in the development of continuous and robust non-co...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/1361-6579/ab525c
更新日期:2019-12-02 00:00:00
abstract::Balance is the ability to maintain equilibrium while sitting or standing. There are a number of different methods which are used to assess balance: technical methods such as sway magnetometry, ataxia meter and force platforms, and clinical methods such as the functional reach test, Berg balance test and fall risk inde...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/21/4/309
更新日期:2000-11-01 00:00:00
abstract::The goal of the present study was to develop and evaluate a new method for the prediction of unexplained syncope occurrences. Diagnosis of syncope is currently based on the reproduction of symptoms in combination with hypotension and bradycardia induced by a 45 min 60-70 degrees head-upright tilt test (HUTT). The main...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/28/2/007
更新日期:2007-02-01 00:00:00
abstract::Monitoring the brain state in anaesthesia is crucial for clinical doctors. In this study, we propose a novel nonlinear method, the permutation Lempel-Ziv complexity (PLZC) index, which describes the complexity in the electroencephalographic (EEG) signal to quantify the effect of GABAergic anaesthetics on brain activit...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/36/12/2483
更新日期:2015-12-01 00:00:00
abstract::There has been a surge of interest in using electrical impedance tomography (EIT) for monitoring regional lung ventilation, however, EIT is an ill-conditioned problem, and errors/noise in the boundary voltages can have an undesirable effect on the quality of the final image. Most EIT systems in clinical usage use seri...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/34/6/659
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Walking is a complex human behavior, usually performed in a dynamic environment. Gait parameters are thought to reflect this complexity. Re-Step™ is a therapy system in the form of a computerized shoe, originally developed for the training and rehabilitation of individuals with brain damage. Th...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/1361-6579/aab659
更新日期:2018-04-26 00:00:00
abstract::The activPAL™ activity monitor has potential for use in youth with Cerebral Palsy (CP) as it has demonstrated acceptable validity for the assessment of sedentary and physical activity in other populations. This study determined the validity of the activPAL™ activity monitor for the measurement of sitting, standing, wa...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/35/11/2307
更新日期:2014-11-01 00:00:00
abstract::The ability to image the impedance changes that accompany neuronal depolarization in the brain would constitute a major advance in neuroscience technology. Unfortunately, these changes are likely to be small and rapid and so difficult to measure. The impedance change at frequencies above 10 kHz, as used by conventiona...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/16/3a/009
更新日期:1995-08-01 00:00:00
abstract::Although previous studies have established the feasibility of monitoring esophageal temperature during radiofrequency cardiac ablation using an esophageal temperature probe (ETP), some questions remain regarding its efficacy. The aims of this study were to study the effect of the location of the ETP on the temperature...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/28/5/001
更新日期:2007-05-01 00:00:00
abstract::There is considerable interest in unobtrusive and portable methods of monitoring sleepiness outside the laboratory setting. This study evaluates the usefulness of combined electrocardiogram (ECG) and photoplethysmogram (PPG) measurements for estimating psychomotor vigilance. The psychomotor vigilance test (PVT) was pe...
journal_title:Physiological measurement
pub_type: 杂志文章
doi:10.1088/0967-3334/29/8/001
更新日期:2008-08-01 00:00:00
abstract::In the present study, laser Doppler measurement was used to quantitatively investigate the microcirculatory effects of contact pressure stimulation (PS) underneath the Hoku acupoint and its nearby nonacupoint, to improve the understanding of the mechanisms underlying acupressure therapy. A control group (no PS applied...
journal_title:Physiological measurement
pub_type: 临床试验,杂志文章
doi:10.1088/0967-3334/31/6/007
更新日期:2010-06-01 00:00:00