Cyclin D3 interacts with human activating transcription factor 5 and potentiates its transcription activity.

abstract：:In the bone matrix, insulin-like growth factors (IGFs) are the most abundant growth factors and IGF binding protein 5 (IGFBP-5) is the major IGFBP. Our previous study suggested that IGFs stored in the bone matrix and prostate-specific antigen (PSA) play an important role in prostate cancer (PC) bone metastasis. Howeve...

journal_title：Biochemical and biophysical research communications

authors： Maeda H,Yonou H,Yano K,Ishii G,Saito S,Ochiai A

更新日期：2009-04-10 00:00:00

abstract：:High serum selenium levels have been associated epidemiologically with increased incidence of type 2 diabetes. The major fraction of total selenium in serum is represented by liver-derived selenoprotein P (SeP). This study was undertaken to test for a hypothesized effect of hyperglycemia and the antihyperglycemic drug...

journal_title：Biochemical and biophysical research communications

authors： Speckmann B,Sies H,Steinbrenner H

更新日期：2009-09-11 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) play crucial roles in tumor development of osteosarcoma (OS). LncRNA PCAT6 was involved in the progression of multiple human cancers. However, the biological function of PCAT6 in OS remains largely unknown. We found that PCAT6 was elevated in OS tissues relative to that in their adjacent ...

journal_title：Biochemical and biophysical research communications

authors： Zhu C,Huang L,Xu F,Li P,Li P,Hu F

更新日期：2020-01-08 00:00:00

abstract：:To understand the structural basis in the hormone-dependent transcriptional regulation of human beta 1 thyroid hormone receptor (h-TR beta 1), we characterized the region which interacted with the thyroid hormone, 3,3',5-triiodo-L-thyronine (T3). Using the hormone binding domain of h-TR beta 1 (K206-D461) as an immuno...

journal_title：Biochemical and biophysical research communications

authors： Bhat MK,McPhie P,Cheng SY

更新日期：1995-05-16 00:00:00

abstract：:The secretory proteins from adrenal chromaffin granules, chromogranins A, A1 and A2, were found to be excellent in vitro methyl acceptor proteins. The purified protein-carboxyl methylase (PCM) from bovine erythrocytes incorporated 660, 2540 and 7890 pmol of methyl group/10 min/mg protein in chromogranins A, A1 and A2,...

journal_title：Biochemical and biophysical research communications

authors： Veeraragavan K,Coulombe R,Gagnon C

更新日期：1988-04-29 00:00:00

abstract：:Mutants of mouse T-lymphoma S49 cells lacking thymidine kinase activity or deficient in nucleoside transport were selected by growth in the presence of 5'-fluorodeoxyuridine and their sensitivity to interferon tested. All five thymidine kinase and both transport deficient mutants were sensitive to the antiproliferativ...

journal_title：Biochemical and biophysical research communications

authors： Gewert DR,Cohen A,Williams BR

更新日期：1984-01-13 00:00:00

abstract：:Specification to primordial germ cells (PGCs) is mediated by mesoderm-induction signals during gastrulation. We found that Akt activation during in vitro mesodermal differentiation of embryonic stem cells (ESCs) generated self-renewing spheres with differentiation states between those of ESCs and PGCs. Essential regul...

journal_title：Biochemical and biophysical research communications

authors： Yamano N,Kimura T,Watanabe-Kushima S,Shinohara T,Nakano T

更新日期：2010-02-12 00:00:00

abstract：:The monoclonal antibody 6E2 raised against the embryonal carcinoma cell line NCR-G3 had been shown to also react with human germ cells. Thin-layer chromatography (TLC) immunostaining revealed that 6E2 specifically reacts with sialosylglobopenta osylceramide (sialylGb5), which carries an epitope of stage-specific embry...

journal_title：Biochemical and biophysical research communications

authors： Sato B,Katagiri YU,Miyado K,Akutsu H,Miyagawa Y,Horiuchi Y,Nakajima H,Okita H,Umezawa A,Hata J,Fujimoto J,Toshimori K,Kiyokawa N

更新日期：2007-12-28 00:00:00

abstract：:NADPH oxidases (NOX) - derived reactive oxygen species (ROS) contribute to oxidative injury in hypoxia-induced pulmonary arterial hypertension. This study aims to evaluate the status of NOX in endothelial progenitor cells (EPCs) under hypoxic condition and to determine whether NOX inhibitors could attenuate hypoxia-in...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Ren KD,Peng JJ,Li T,Luo XJ,Fan C,Yang JF,Peng J

更新日期：2017-01-22 00:00:00

abstract：:Recent reports have indicated that circular RNA (circRNA) may regulate Lung adenocarcinoma (LAC) development. Our previous studies showed that hsa_circ_0012673 was up-regulated in a circRNA microarray. However, its expression level in LAC has not been verified, and the underlying molecular mechanisms in LAC are unknow...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Zhu X,Zhang H,Wei S,Chen Y,Chen Y,Wang F,Fan X,Han S,Wu G

更新日期：2018-02-19 00:00:00

abstract：:We have studied the functional properties of an alternately spliced form of sheep testicular FSH receptor cDNA that codes for a protein similar to a previously described active receptor but differs in the carboxy terminus in sequence and is also shorter by 25 residues. The receptor expressed in HEK 293 cells fails to ...

journal_title：Biochemical and biophysical research communications

authors： Sairam MR,Jiang LG,Yarney TA,Khan H

更新日期：1996-09-24 00:00:00

abstract：:L1210/VCR cell line (R) was obtained by adaptation of the L1210 mouse leukaemia cells (S) to vincristine and showed P-glycoprotein (P-gp) mediated multidrug resistance (MDR). R cells were observed to be more sensitive to high external calcium as parental S. More pronounced calcium uptake was observed for R cells. More...

journal_title：Biochemical and biophysical research communications

authors： Sulová Z,Orlický J,Fiala R,Dovinová I,Uhrík B,Seres M,Gibalová L,Breier A

更新日期：2005-09-30 00:00:00

abstract：:One important criteria for a plasma circulating hemoglobin blood substitute is resistance to subunit dissociation. For this reason, cross-linked hemoglobins (with low oxygen affinities) are being specifically designed to serve as potential blood substitutes. An example is HbXL99 alpha, cross-linked between the alpha-s...

journal_title：Biochemical and biophysical research communications

authors： Hirsch RE,Friedman JM,Harrington JR,Scarlata SF,Harrington JP

更新日期：1994-05-16 00:00:00

abstract：:Ultrasound (US) has emerged as a promising noninvasive modality for neuromodulation. Despite previous evidence that US may mediate cellular response by activating mechanosensitive ion channels embedded in the cell membrane, the underlying mechanism is not well understood. In this work, we developed a vertically deploy...

journal_title：Biochemical and biophysical research communications

authors： Liao D,Li F,Lu D,Zhong P

更新日期：2019-10-20 00:00:00

abstract：:We generated a three-dimensional (3-D) model of human airway tissues in order to study initiation of inhalational form of anthrax infection. The system was designed to model the air-blood barrier of the respiratory tract represented by epithelial cells and macrophages. When grown on collagen/fibronectin gel support at...

journal_title：Biochemical and biophysical research communications

authors： Radyuk SN,Mericko PA,Popova TG,Grene E,Alibek K

更新日期：2003-06-06 00:00:00

abstract：:Wheat germ phosphoglycerate mutase, exposed to 3.4 M guanidinium chloride at 22 degrees C and pH 7.8, slowly undergoes time-dependent inactivation which can be fully reversed by adding excess Co2+ or Mn2+ to a 50-fold dilution of the denaturing medium. Titration of the denatured enzyme with either Co2+ or Mn2+ shows t...

journal_title：Biochemical and biophysical research communications

authors： Smith GC,McWilliams AD,Hass LF

更新日期：1986-04-14 00:00:00

abstract：:The gene encoding the human puromycin-sensitive aminopeptidase (PSA) has been cloned and characterized. The human PSA gene is composed of 23 exons and 22 introns and spans approximately 40 kb of chromosome 17 at the interval 17q12-21. An analysis of the 5' end of the human PSA transcript reveals that the translational...

journal_title：Biochemical and biophysical research communications

authors： Thompson MW,Tobler A,Fontana A,Hersh LB

更新日期：1999-05-10 00:00:00

abstract：:The Rv2477c protein of Mycobacterium tuberculosis (Mtb) belongs to the ATP-binding cassette (ABC) subfamily F that contains proteins with tandem nucleotide-binding domains but lacking transmembrane domains. ABC-F subfamily proteins have been implicated in diverse cellular processes such as translation, antibiotic resi...

journal_title：Biochemical and biophysical research communications

authors： Daniel J,Abraham L,Martin A,Pablo X,Reyes S

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The prognosis of patients after acute kidney injury (AKI) is poor and treatment is limited. AKI is mainly caused by renal ischemia/reperfusion injury (IRI). During the extension phase of IRI, endothelial damage may participate in ischemia and inflammation. Endothelin-1 (ET-1) which is mostly secreted by endo...

journal_title：Biochemical and biophysical research communications

authors： Arfian N,Emoto N,Vignon-Zellweger N,Nakayama K,Yagi K,Hirata K

更新日期：2012-08-24 00:00:00

abstract：:The effect of glucocorticoid hormones on the protein responsible for both nucleotide pyrophosphatase (EC 3.6.1.9) and alkaline phosphodiesterase I (EC 3.1.4.1) activities was examined in murine MOPC 315 plasmacytoma cells. Incubation of these cells with dexamethasone resulted in parallel increases in pyrophosphatase a...

journal_title：Biochemical and biophysical research communications

authors： Rebbe NF,Hickman S

更新日期：1991-03-15 00:00:00

abstract：:Cilia/flagella are evolutionarily conserved cellular organelles. In this study, we demonstrated that Dunaliella salina Peroxiredoxin 1 (DsPrdx1) localized to the flagella and basal bodies, and was involved in flagellar disassembly. The link between DsPrdx1 and flagella of Dunaliella salina (D. salina) encouraged us to...

journal_title：Biochemical and biophysical research communications

authors： Gong F,Liu H,Li J,Xue L,Zhang M

更新日期：2014-02-14 00:00:00

abstract：:The red-ox reactions of the dinuclear iron center of mouse R2 protein upon interaction with different reductants (dithionite alone and with mediators) and oxidants (PES, methylene blue, hydrogen peroxide and para-benzoquinone) have been studied by EPR and optical spectroscopy. The obtained results indicate that the tr...

journal_title：Biochemical and biophysical research communications

authors： Davydov A,Schmidt PP,Gräslund A

更新日期：1996-02-06 00:00:00

abstract：:Fecal supernatant or serum containing TT virus (TTV) of genotype 1a (10(5) copies/ml) from patients with acute TTV infection was inoculated intravenously into two naive chimpanzees. Serum samples were obtained weekly and tested for TTV DNA by genotype 1-specific polymerase chain reaction. TTV DNA was detected in chimp...

journal_title：Biochemical and biophysical research communications

authors： Tawara A,Akahane Y,Takahashi M,Nishizawa T,Ishikawa T,Okamoto H

更新日期：2000-11-19 00:00:00

abstract：:The enzymatic mechanism of a small ribosome-inactivating protein, gamma-momorcharin, purified from the seeds of Momordica charantia, has been characterized. By SDS-polyacrylamide and electrospray ionization mass spectrometry, its molecular weight was measured to be 11,500 daltons which is much lower than other RIPs kn...

journal_title：Biochemical and biophysical research communications

authors： Pu Z,Lu BY,Liu WY,Jin SW

更新日期：1996-12-04 00:00:00

abstract：:Using minimum energy calculations and molecular dynamics techniques the preferred conformational states of LHRH and its analogues have been reported to involve a modified beta-bend between residues 5 to 8. Based on some of these models cyclic peptide analogues of LHRH antagonists were synthesised using solid phase pep...

journal_title：Biochemical and biophysical research communications

authors： Dutta AS,Gormley JJ,McLachlan PF,Woodburn JR

更新日期：1989-03-31 00:00:00

abstract：:The DNA-dependent DNA polymerase (DDDP) and RNA-dependent DNA polymerase (RDDP) activities of hepadnavirus polymerases are both essential for viral replication. Human hepatitis B virus (HBV) polymerase has been successfully expressed in Escherichia coli as a fusion protein in frame with maltose-binding protein. The pr...

journal_title：Biochemical and biophysical research communications

authors： Jeong JH,Kwak DS,Rho HM,Jung G

更新日期：1996-06-14 00:00:00

abstract：:Major histocompatibility complex (MHC)-loading enhancers (MLE) have recently attracted attention because of their ability to enhance the efficacy of peptide immunotherapeutics. As small molecular weight compounds, they influence the loading of peptides in MHC molecules by converting them from a non-receptive to a rece...

journal_title：Biochemical and biophysical research communications

authors： Afridi S,Shaheen F,Roetzschke O,Shah ZA,Abbas SC,Siraj R,Makhmoor T

更新日期：2015-01-16 00:00:00

abstract：:Cripto is a cell surface protein highly expressed in certain solid tumors, and overexpression of Cripto protein is oncogenic. Cripto-1 protein is encoded by CRIPTO1 gene. CRIPTO3, a presumed pseudogene, has an open reading frame with six amino acid differences from Cripto-1. We show that CRIPTO3 mRNA is the CRIPTO mes...

journal_title：Biochemical and biophysical research communications

authors： Sun C,Orozco O,Olson DL,Choi E,Garber E,Tizard R,Szak S,Sanicola M,Carulli JP

更新日期：2008-12-05 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors are calcium-permeable ion channels assembled from four subunits that each have a common membrane topology. The intracellular carboxyl terminal domain (CTD) of each subunit varies in length, is least conserved between subunits, and binds multiple intracellular proteins. We defined ...

journal_title：Biochemical and biophysical research communications

authors： Bajaj G,Hau AM,Hsu P,Gafken PR,Schimerlik MI,Ishmael JE

更新日期：2014-02-21 00:00:00

abstract：:The Ca(2+)-binding S100A1 protein displays a specific and high expression level in the human myocardium and is considered to be an important regulator of heart contractility. Diminished protein levels detected in dilated cardiomyopathy possibly contribute to impaired Ca(2+) handling and contractility in heart failure....

journal_title：Biochemical and biophysical research communications

authors： Kiewitz R,Acklin C,Schäfer BW,Maco B,Uhrík B,Wuytack F,Erne P,Heizmann CW

更新日期：2003-06-27 00:00:00