Transmission of human TT virus of genotype 1a to chimpanzees with fecal supernatant or serum from patients with acute TTV infection.

abstract：:In cardiac myocytes, cromakalim (BRL 34915), a potassium channel opener, activates a time-independent K+ current exhibiting poor voltage-sensitivity. This effect of cromakalim is antagonized by low concentrations of glibenclamide, a specific blocker of ATP-dependent K+ channels in cardiac cells. Direct recording of th...

journal_title：Biochemical and biophysical research communications

authors： Escande D,Thuringer D,Leguern S,Cavero I

更新日期：1988-07-29 00:00:00

abstract：:Most studies characterizing H-ras have been conducted in constitutively expressing cell lines. To explore the early interaction between H-ras p21 and signal transduction systems we have utilized an NIH3T3 fibroblast line transfected with a steroid inducible MMTV H-ras vector. Exposure to dexamethasone resulted in tran...

journal_title：Biochemical and biophysical research communications

authors： Murphy SK,Lindberg JB,Prussack DA

更新日期：1994-12-15 00:00:00

abstract：:Six forms of cytochrome P-450 in the mitochondria of larvae from Musca domestica were isolated by solubilization with CHAPS followed by ammonium sulfate fractionation and HPLC on an anion-exchange column. Forms 1, 2, 3, 5, and 6 catalyzed the formation of 20-hydroxy-ecdysone from ecdysone in the presence of NADPH and ...

journal_title：Biochemical and biophysical research communications

authors： Srivatsan J,Weirich M,Agosin M

更新日期：1990-02-14 00:00:00

abstract：:The fungal AAL-toxin triggers programmed cell death (PCD) through perturbations of sphingolipid metabolism in AAL-toxin-sensitive plants. While Arabidopsis is relatively insensitive to the toxin, the loh2 mutant exhibits increased susceptibility to AAL-toxin due to the knockout of a gene involved in sphingolipid metab...

journal_title：Biochemical and biophysical research communications

authors： Gechev TS,Ferwerda MA,Mehterov N,Laloi C,Qureshi MK,Hille J

更新日期：2008-10-31 00:00:00

abstract：:An inactive form of acrosin was extracted from epididymal boar spermatozoa utilizing acid pH conditions. When subjected to activation in alkaline environment, this form turns into an enzymatically active species, which exhibits close-related electrophoretic characteristics. Both the precursor and the activated species...

journal_title：Biochemical and biophysical research communications

authors： Berruti G,Merigioli G,Martegani E

更新日期：1986-07-16 00:00:00

abstract：:The functional importance of mitochondrial protein translation has been recently documented in the context of various cancers but not renal cell carcinoma (RCC). In lines with these efforts, our work demonstrates that mitochondrial translation inhibition by tigecycline or depletion of EF-Tu mitochondrial translation f...

journal_title：Biochemical and biophysical research communications

authors： Wang B,Ao J,Yu D,Rao T,Ruan Y,Yao X

更新日期：2017-08-26 00:00:00

abstract：:Pterostilbene, a bioactive component of blueberries and grapes, shows structural similarity to resveratrol, and exhibits antioxidant, anti-inflammatory, anti-cancer, hypoglycemic, and cholesterol lowering effects. Recent evidence indicates that pterostilbene is an agonist of the nuclear receptor, peroxisome proliferat...

journal_title：Biochemical and biophysical research communications

authors： Ren G,Rimando AM,Mathews ST

更新日期：2018-04-06 00:00:00

abstract：:Transgenic mouse which produces human alpha-fetoprotein (AFP) ubiquitously was used to study carbohydrate structures of AFP produced by various tissues as well as that in the serum. A series of tissues from the transgenic mouse were cultured in vitro and the AFP produced was analyzed by affinity electrophoreses with 4...

journal_title：Biochemical and biophysical research communications

authors： Koyama Y,Sakai M,Kitagawa T,Taketa K,Nishi S

更新日期：1996-06-25 00:00:00

abstract：:Tuberous sclerosis complex 2 (TSC2) is a tumor-suppressor protein that is partially regulated by insulin, energy, oxygen, and growth factors. Mutations in the TSC2 gene and loss of TSC2 promote cell growth by the mammalian target of rapamycin complex 1 (mTORC1) activation. Furthermore, S-adenosylmethionine (SAM) senso...

journal_title：Biochemical and biophysical research communications

authors： Gen S,Matsumoto Y,Suzuki T,Inoue J,Yamamoto Y

更新日期：2021-01-19 00:00:00

abstract：:The in vitro heat effect on protein characteristics of thermostable enzyme was examined using a cyclodextrin glucanotransferase (CGTase, EC 2.4.1.19) from the hyperthermophilic archaeon Thermococcus sp. B1001 as a model protein. The recombinant form of CGTase was obtained as an inclusion body from Escherichia coli cel...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto T,Shiraki K,Fujiwara S,Takagi M,Fukui K,Imanaka T

更新日期：1999-11-01 00:00:00

abstract：:Serum prealbumin isolated from a Japanese patient with familial amyloidotic polyneuropathy (FAP) has been found to consist of a mixture of normal prealbumin and a prealbumin variant which contains a methionine for valine substitution at position 30. The prealbumin variant in the serum is identical to the prealbumin va...

journal_title：Biochemical and biophysical research communications

authors： Nakazato M,Kangawa K,Minamino N,Tawara S,Matsuo H,Araki S

更新日期：1984-07-31 00:00:00

abstract：:Glucocorticoids inhibit rodent alpha-fetoprotein (AFP) gene activity but stimulate expression of the human homologue. Like human, activity of the AFP promoter from other primates was stimulated by the synthetic glucocorticoid dexamethasone (Dex) in various cell lines. A glucocorticoid responsive element (GRE) is locat...

journal_title：Biochemical and biophysical research communications

authors： Nakabayashi H,Koyama Y,Sakai M,Li HM,Wong NC,Nishi S

更新日期：2001-09-14 00:00:00

abstract：:The ouabain-resistant and ouabain-sensitive alpha-subunit cRNAs in various molar ratios were injected into Xenopus oocytes together with cRNA for the beta-subunit. The ouabain-resistant ATPase activity, as well as ouabain-resistant Rb+ uptake, of the injected oocytes increased linearly with increasing the amount of cR...

journal_title：Biochemical and biophysical research communications

authors： Takeda K,Kawamura M

更新日期：2001-02-09 00:00:00

abstract：:Neutrophils stimulated with a low concentration of chemotactic peptide N-formyl-met-leu-phe respond with a brief pulse of actin polymerization and a persistent change in morphology from round to polarized. The recovery of the actin polymerization response is unlikely to be due to usual receptor desensitization mechani...

journal_title：Biochemical and biophysical research communications

authors： Model MA,Omann GM

更新日期：1996-07-16 00:00:00

abstract：:Mutations of the microtubule (MT)-associated protein Doublecortin X (DCX) gene disrupt cortical layering in brain development. Whilst many of these pathogenic DCX mutations are within the doublecortin domains (DC1 and DC2) that mediate direct DCX-MT association, a pathogenic mutation DCX E2K that causes cognitive impa...

journal_title：Biochemical and biophysical research communications

authors： Moslehi M,Ng DCH,Bogoyevitch MA

更新日期：2019-06-04 00:00:00

abstract：:Viral vectors displaying specific ligand binding moieties have raised an increasing interest in the area of targeted gene therapy. In this report, we describe baculovirus vectors displaying either a functional single chain antibody fragment (scFv) specific for the carcinoembryonic antigen (CEA) or the synthetic IgG bi...

journal_title：Biochemical and biophysical research communications

authors： Ojala K,Mottershead DG,Suokko A,Oker-Blom C

更新日期：2001-06-15 00:00:00

abstract：:The ATPase activity of F1 isolated from the thermophilic bacterium PS3 is stimulated at 30 degrees C by the anionic detergents cholate or deoxycholate. Maximal activity obtained with these detergents (35 mumol/min X mg) is similar to the activity reported for the optimal temperature, 75 degrees C. The activity is line...

journal_title：Biochemical and biophysical research communications

authors： Norling B

更新日期：1986-05-14 00:00:00

abstract：:We investigated the molecular mechanism underlying the neuroprotective effect of theanine, a green tea component, using primary cultured rat cortical neurons, focusing on group I metabotropic glutamate receptors (mGluRs). Theanine and a group I mGluR agonist, DHPG, inhibited the delayed death of neurons caused by brie...

journal_title：Biochemical and biophysical research communications

authors： Nagasawa K,Aoki H,Yasuda E,Nagai K,Shimohama S,Fujimoto S

更新日期：2004-07-16 00:00:00

abstract：:Explaining why type I collagens are preferentially preserved in the geological time scale remains a challenge. Several pieces of evidence indicate that its rich content in the bone and its unique, stable structure played key roles in its preservation. By considering the distinct thermal stability of amino acids, we re...

journal_title：Biochemical and biophysical research communications

authors： Wang SY,Cappellini E,Zhang HY

更新日期：2012-05-25 00:00:00

abstract：:The genetic encoding of synthetic or "non-natural" amino acids promises to diversify the functions and structures of proteins. We applied rapid codon-reassignment for creating Escherichia coli strains unable to terminate translation at the UAG "stop" triplet, but efficiently decoding it as various tyrosine and lysine ...

journal_title：Biochemical and biophysical research communications

authors： Mukai T,Yanagisawa T,Ohtake K,Wakamori M,Adachi J,Hino N,Sato A,Kobayashi T,Hayashi A,Shirouzu M,Umehara T,Yokoyama S,Sakamoto K

更新日期：2011-08-12 00:00:00

abstract：:The cell membrane and the nuclear membrane are two major barriers hindering the free movement of various macromolecules through animal cells. Nevertheless, some proteins can actively bypass these barriers by dint of intrinsic peptidic signals, so incorporation of these signals might improve the efficacy of artificial ...

journal_title：Biochemical and biophysical research communications

authors： Akuta T,Eguchi A,Okuyama H,Senda T,Inokuchi H,Suzuki Y,Nagoshi E,Mizuguchi H,Hayakawa T,Takeda K,Hasegawa M,Nakanishi M

更新日期：2002-10-04 00:00:00

abstract：:The regulated secretory pathway is a specialized form of protein secretion found in endocrine and neuroendocrine cell types. Pro-opiomelanocortin (POMC) is a pro-hormone that utilizes this pathway to be trafficked to dense core secretory granules (DCSGs). Within this organelle, POMC is processed to multiple bioactive ...

journal_title：Biochemical and biophysical research communications

authors： Dirk BS,End C,Pawlak EN,Van Nynatten LR,Jacob RA,Heit B,Dikeakos JD

更新日期：2018-12-09 00:00:00

abstract：:This article has been withdrawn consistent with Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). The Publisher apologizes for any inconvenience this may cause. ...

journal_title：Biochemical and biophysical research communications

authors： Cui R,He J,Mei R,de Fromentel CC,Martel-Planche G,Taniere P,Hainaut P

更新日期：2005-08-22 00:00:00

abstract：:Hsp16.3, a small heat shock protein from Mycobacterium tuberculosis (MTB), was originally identified as an immuno-dominant antigen and later found to be a major membrane protein. In vitro studies show that Hsp16.3 exists as nonamers and undergoes dynamic dissociation/re-association equilibrium in solutions. Neverthele...

journal_title：Biochemical and biophysical research communications

authors： Zhang H,Fu X,Jiao W,Zhang X,Liu C,Chang Z

更新日期：2005-05-20 00:00:00

abstract：:The role of hyaluronan binding protein 1 (HABP1) in cell signaling was investigated and in vitro kinase assay demonstrated that it is a substrate for MAP kinase. Phosphorylation of endogenous HABP1 was also observed following treatment of J774 cells with PMA. HABP1 was coimmunoprecipitated with activated ERK, confirmi...

journal_title：Biochemical and biophysical research communications

authors： Majumdar M,Meenakshi J,Goswami SK,Datta K

更新日期：2002-03-08 00:00:00

abstract：:Resident mouse peritoneal macrophages in culture spontaneously secrete lipoprotein lipase. Secretion of lipoprotein lipase was 10-fold greater in thioglycollate-elicited and 6-fold greater in mineral oil-elicited macrophages. The increase in enzyme secretion was dependent on protein synthesis and glycosylation of the ...

journal_title：Biochemical and biophysical research communications

authors： Goldberg DI,Khoo JC

更新日期：1987-01-15 00:00:00

abstract：:The objective of this study was to investigate the exact therapeutic effects of Verapamil on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the molecular mechanism involved, through using LPS-induced animal models as well as LPS-stimulated mouse primary peritoneal macrophages models. Our results demonstr...

journal_title：Biochemical and biophysical research communications

authors： Song Z,Li S,Zhang C,Yuan L,Han L,Liu Y

更新日期：2019-10-01 00:00:00

abstract：:Although leukotriene B4 (LTB4) has been reported to stimulate monocytes and neutrophils, its role on dendritic cell (DC) activity has not been examined. Here, we investigated the expression of LTB4 receptor and the effect of LTB4 on human DC chemotaxis. We analyzed LTB4 receptors, BLT1 and BLT2, by using RT-PCR. DCs e...

journal_title：Biochemical and biophysical research communications

authors： Shin EH,Lee HY,Bae YS

更新日期：2006-09-22 00:00:00

abstract：:Artificial DNA binding peptides recognizing separated sequences would expand varieties of the target genes for desirable transcriptional control. Here we demonstrated that polyarginine linker between two 3-zinc finger domains gives DNA binding selectivity to the separated target sequences. We created a six-zinc finger...

journal_title：Biochemical and biophysical research communications

authors： Imanishi M,Yan W,Morisaki T,Sugiura Y

更新日期：2005-07-22 00:00:00

abstract：:The membrane electroporation-induced inward current (IMEP) in pituitary tumor (GH3) cells was characterized. This current emerges irregularly when membrane hyperpolarizations to -200 mV with a holding potential of -80 mV were elicited. Neither E-4031 (10 μM), glibenclamide (30 μM), nor ZD7288 (30 μM) caused any effect...

journal_title：Biochemical and biophysical research communications

authors： Wu SN,Huang HC,Yeh CC,Yang WH,Lo YC

更新日期：2011-02-18 00:00:00