WITHDRAWN: Expression of p53, p63, and p73 isoforms in squamous cell carcinoma and adenocarcinoma of esophagus☆,☆☆

abstract：:Brush border membrane vesicles (BBMVs) prepared from midguts of Choristoneura fumiferana larvae were pretreated separately with the three CryIA delta-endotoxins from Bacillus thuringiensis subsp. kurstaki HD-1. Crossed affinity immunoelectrophoresis of the solubilized toxin-BBMV complexes, using antibodies raised agai...

journal_title：Biochemical and biophysical research communications

authors： Pang AS

更新日期：1994-03-30 00:00:00

abstract：:Transient receptor potential (TRP) proteins are cation channels that comprise a superfamily of molecular sensors that enable animals to detect a wide variety of environmental stimuli. This versatility enables vertebrate and invertebrate TRP channels to function in a diversity of senses, ranging from vision to taste, s...

journal_title：Biochemical and biophysical research communications

authors： Liu C,Montell C

更新日期：2015-04-24 00:00:00

abstract：:Src homology 2 (SH2) domains mediate phosphotyrosine (pY)-dependent protein:protein interactions involved in signal transduction pathways. We have found that the SH2 domains of the 85-kDa alpha subunit (p85) of phosphatidylinositol 3-kinase (PI3 kinase) bind directly to the serine/threonine kinase A-Raf. In this repor...

journal_title：Biochemical and biophysical research communications

authors： Fang Y,Johnson LM,Mahon ES,Anderson DH

更新日期：2002-02-01 00:00:00

abstract：:The crude extracts from Sphingomonas paucimobilus containing 2-hydroxy fatty acid-rich sphingolipids were found to oxidize [1-14C]-myristate to 2-hydroxymyristate in the presence of NADH. The myristate-oxidation activity was partially purified about 290-fold from the cell-free extracts by ammonium sulfate fractionatio...

journal_title：Biochemical and biophysical research communications

authors： Matsunaga I,Kusunose E,Yano I,Ichihara K

更新日期：1994-06-30 00:00:00

abstract：:Hematopoiesis is a complex process tightly controlled by sets of transcription factors in a context-dependent and stage-specific manner. Smad2/3 transcription factor plays a central role in differentiation and survival of erythroid cells. Here we report that follistatin-like 1 (FSTL1) treatment impairs hemin-induced e...

journal_title：Biochemical and biophysical research communications

authors： Wu J,Dong Y,Teng X,Cheng M,Shen Z,Chen W

更新日期：2015-10-30 00:00:00

abstract：:Temozolomide (TMZ) is a methylating agent used in chemotherapy against glioblastoma. This work was designed to clarify details in repair pathways acting to remove DNA double-strand breaks (DSBs) induced by TMZ. Cultured mouse embryonic fibroblasts were used which were deficient in DSB repair genes such as homologous r...

journal_title：Biochemical and biophysical research communications

authors： Kondo N,Takahashi A,Mori E,Ohnishi K,McKinnon PJ,Sakaki T,Nakase H,Ohnishi T

更新日期：2009-10-02 00:00:00

abstract：:RBM39, also known as splicing factor HCC1.4, acts as a transcriptional coactivator for the steroid nuclear receptors JUN/AP-1, ESR1/ER-α and ESR2/ER-β. RBM39 is involved in the regulation of the transcriptional responses of these steroid nuclear receptors and promotes transcriptional initiation. In this paper, we repo...

journal_title：Biochemical and biophysical research communications

authors： Mai S,Qu X,Li P,Ma Q,Liu X,Cao C

更新日期：2016-04-22 00:00:00

abstract：:Mutual interactions between adipocytes and immune cells in white adipose tissue (WAT) are involved in modulation of lipid metabolism in the tissue and also in response to omega-3 polyunsaturated fatty acids (PUFA), which counteract adverse effects of obesity. This complex interplay depends in part on in situ formed an...

journal_title：Biochemical and biophysical research communications

authors： Kuda O,Rombaldova M,Janovska P,Flachs P,Kopecky J

更新日期：2016-01-15 00:00:00

abstract：:The antiherpetic agent 9-beta-D-arabinofuranosyladenine (araA) needs to be phosphorylated to its 5'-triphosphate to be effective as an inhibitor of herpes simplex virus replication. Adenosine kinase and deoxycytidine kinase are assumed to convert araA to its 5'-monophosphate. We now found that araAMP is converted to i...

journal_title：Biochemical and biophysical research communications

authors： Balzarini J,De Clercq E

更新日期：1990-12-31 00:00:00

abstract：:The biological function of hnRNP family proteins is widely diverse and involved in pre-mRNA processing, transcriptional regulation, recombination, and telomere maintenance. In the course of our study on the elucidation of biological functions of minisatellite DNA, we isolated several nuclear proteins that bind to the ...

journal_title：Biochemical and biophysical research communications

authors： Tanaka E,Fukuda H,Nakashima K,Tsuchiya N,Seimiya H,Nakagama H

更新日期：2007-06-29 00:00:00

abstract：:Sphingosine-1-phosphate (S1P)-induced migration and proliferation of endothelial cells are critical for angiogenesis. C2H2-zinc finger (ZNF) proteins usually play an essential role in altering gene expression and regulating the angiogenesis. The aim of this study is to investigate whether a novel human C2H2-zinc finge...

journal_title：Biochemical and biophysical research communications

authors： Sun HY,Wei SP,Xu RC,Xu PX,Zhang WC

更新日期：2010-05-07 00:00:00

abstract：:An apparently novel human plasma and urinary protein of low molecular weight was isolated from several highly purified preparations of protein HC by gel chromatography and high voltage electrophoresis with a yield of about 8 mg/g. The protein has a molecular weight of about 20,000, neutral electrophoretic mobility at ...

journal_title：Biochemical and biophysical research communications

authors： López-Otin C,Grubb AO,Méndez E

更新日期：1983-11-30 00:00:00

abstract：:We have developed a new and rapid immunofluorescent method for visualisation of replicated regions on fixed DNA fibers. Using this method we have found in 5-fluorodeoxyuridine (FrdU)-blocked human cells distinct replication units covering about 60 kb of DNA and corresponding in size to single replicons or chromatin lo...

journal_title：Biochemical and biophysical research communications

authors： Tomilin N,Rosanov Yu,Zenin V,Bozhkov V,Vig B

更新日期：1993-01-15 00:00:00

abstract：:DJ-1, a product of the DJ-1/PARK7 gene, has been suggested to play various functions involved in transcriptional regulation, protease activity, anti-oxidative stress activity, and regulation of mitochondrial complex I. Such a variety of functions of DJ-1 are supposed to be realized through interactions with different ...

journal_title：Biochemical and biophysical research communications

authors： Yasuda T,Kaji Y,Agatsuma T,Niki T,Arisawa M,Shuto S,Ariga H,Iguchi-Ariga SM

更新日期：2013-06-28 00:00:00

abstract：:Mycobacterium tuberculosis (TB) small heat shock protein Hsp16.3 was found to be a major membrane protein that is most predominantly expressed under oxidative stress and is localized to the thickened cell envelope. Gene knock-out studies indicate that the Hsp16.3 protein is required for TB to grow in its host macropha...

journal_title：Biochemical and biophysical research communications

authors： Abulimiti A,Qiu X,Chen J,Liu Y,Chang Z

更新日期：2003-05-23 00:00:00

abstract：:The serine proteinase catalyzed hydrolysis of N-ethoxycarbonyl-D-phenylalanyl-L-prolyl-alpha-azalysine p- nitrophenyl ester (Eoc-D-Phe-Pro-azaLys-ONp) was investigated at pH 6.2 and 21.0 degrees C. The results are consistent with the minimum three-step catalytic mechanism. The acylation step is rate limiting for human...

journal_title：Biochemical and biophysical research communications

authors： Balliano G,Milla P,Giordano C,Gallina C,Coletta M,Menegatti E,Rizzi M,Bolognesi M,Ascenzi P

更新日期：1996-08-14 00:00:00

abstract：:Interleukin 6 is a cytokine with growth and differentiation activities on a number of cell types. Human articular chondrocytes produce interleukin 6 and this production appears to be constitutive but can be stimulated in a dose-dependent manner by interleukin 1. Other stimulators of interleukin 6 production in chondro...

journal_title：Biochemical and biophysical research communications

authors： Bunning RA,Russell RG,Van Damme J

更新日期：1990-02-14 00:00:00

abstract：:Gastric cancer (GC) remains a serious threat to human health with a high cancer-related death rate and unsatisfactory treatment effects after curative resection, especially with advanced GC. Thus, exploration of the molecular mechanism of cisplatin (CDDP) resistance in GC is crucial. circCCDC66 (hsa_circ_0001313) expr...

journal_title：Biochemical and biophysical research communications

authors： Zhang Q,Miao Y,Fu Q,Hu H,Chen H,Zeng A,Jin Y,Jiang Y,Qian L,Wu L,Xu L,Wang G,Qiu L,Huang X,Xia Y

更新日期：2020-06-04 00:00:00

abstract：:c-Fes plays pivotal roles in angiogenic cellular responses of endothelial cells. Here we examined the role of c-Fes in vascular endothelial growth factor-A (VEGF-A)-mediated signaling pathways in endothelial cells. We introduced either wild-type or kinase-inactive c-Fes in porcine aortic endothelial (PAE) cell lines, ...

journal_title：Biochemical and biophysical research communications

authors： Kanda S,Mochizuki Y,Miyata Y,Kanetake H

更新日期：2003-07-11 00:00:00

abstract：:Preadipocytes constitutively express GATA-2 and GATA-3 that are required to halt the cells at the undifferentiated stage. However, we unexpectedly found that K-7174, a GATA-specific inhibitor, did not induce but rather inhibited differentiation of 3T3-L1 preadipocytes. It was associated with lack of lipid accumulation...

journal_title：Biochemical and biophysical research communications

authors： Shimada T,Hiramatsu N,Okamura M,Hayakawa K,Kasai A,Yao J,Kitamura M

更新日期：2007-11-16 00:00:00

abstract：:Transmissible spongiform encephalopathies are fatal neurodegenerative disorders thought to be transmitted by self-perpetuating conformational conversion of a neuronal membrane glycoprotein (PrP(C), for "cellular prion protein") into an abnormal state (PrP(Sc), for "scrapie prion protein"). Doppel (Dpl) is a protein th...

journal_title：Biochemical and biophysical research communications

authors： Erlich P,Cesbron JY,Lemaire-Vieille C,Curt A,Andrieu JP,Schoehn G,Jamin M,Gagnon J

更新日期：2008-01-18 00:00:00

abstract：:The mammalian-target-of-rapamycin (mTOR) is a multidomain protein that is important in regulating several components of the translational machinery. mTOR signalling is stimulated by hormones (e.g., insulin) and by amino acids. Our recent data suggest that TOR signalling responds to intracellular amino acids rather tha...

journal_title：Biochemical and biophysical research communications

authors： Proud CG

更新日期：2004-01-09 00:00:00

abstract：:The gene III protein (pIII) from phi Lf, a filamentous phage of Xanthomonas campestris pv.campestris, was purified by gel filtration with FPLC. The gIII coding region was amplified by PCR, which was then cloned into pUC18 and expressed in Escherichia coli. The size of both pIII, purified from phage particle and expres...

journal_title：Biochemical and biophysical research communications

authors： Liu TJ,You BY,Lin NT,Yang MT,Tseng YH

更新日期：1998-01-06 00:00:00

abstract：:Neonatal hypoxia can induce the persisting brain dysfunctions and subsequently result in the behavioral abnormalities in adulthood. Improving mitochondrial functions were suggested as the effective strategy for brain functional recovery. In this study, we tested the effects of physical exercise, a well-established way...

journal_title：Biochemical and biophysical research communications

authors： Sun L,Ye R,Liang R,Xing F

更新日期：2020-03-05 00:00:00

abstract：:The small GTPase Rheb binds and activates mTORC1, which plays a pivotal role in diverse cellular physiologies. To increase our understanding of how Rheb regulates mTORC1 signaling, we set out to identify Rheb binding proteins using shotgun proteomics approaches. In this study, we characterized HSP70, one of the identi...

journal_title：Biochemical and biophysical research communications

authors： Ryu HH,Ha SH

更新日期：2020-12-17 00:00:00

abstract：:This study provides evidence for the presence of large conductance Ca(2+)-dependent K-channels in guinea pig and human urinary bladder smooth muscle. A23187, a Ca(2+)-ionophore, increased charybdotoxin and iberiatoxin sensitive 42K efflux in human urinary bladder smooth muscle cells, suggesting that large conductance ...

journal_title：Biochemical and biophysical research communications

authors： Trivedi S,Potter-Lee L,Li JH,Yasay GD,Russell K,Ohnmacht CJ,Empfield JR,Trainor DA,Kau ST

更新日期：1995-08-15 00:00:00

abstract：:Diallyl trisulfide (DATS), one of the volatile constituents of garlic oil, has been reported to possess antioxidant, anti-inflammatory, and anti-carcinogenic properties. In this study, DATS (10μmol) given orally for 7days before and for another 7days after starting administration of 2.5% dextran sulfate sodium (DSS) i...

journal_title：Biochemical and biophysical research communications

authors： Lee HJ,Lee HG,Choi KS,Surh YJ,Na HK

更新日期：2013-07-26 00:00:00

abstract：:Gene delivery has become an important tool for biological research and gene therapy trials. Lentiviral vector (LV) mediated gene transfer is a preferred approach for stable, sustained transgenic expression. We report here step-wise development of an Indian human immunodeficiency virus type 2 (HIV-2) isolate derived th...

journal_title：Biochemical and biophysical research communications

authors： Santhosh CV,Tamhane MC,Kamat RH,Patel VV,Mukhopadhyaya R

更新日期：2008-07-04 00:00:00

abstract：:The Adriamycin analog, 3'-(3-cyano-4-morpholinyl)-3'-deaminoadriamycin, is 100- to 1000-fold more active than Adriamycin as an antitumor agent in vivo and in vitro. The interaction of 3'-(3-cyano-4-morpholinyl)-3'deaminoadriamycin and Adriamycin with DNA has been studied in HT-29 human colon carcinoma cells in vitro. ...

journal_title：Biochemical and biophysical research communications

authors： Begleiter A,Johnston JB

更新日期：1985-08-30 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The autophagy pathway has previously been suggested as an important protective factor in liver injury. The purpose of this study is to demonstrate the protective, autophagy-modulating effect of tri-iodothyronine (T3) on liver ischemia reperfusion injury. METHODS:Liver ischemia reperfusion was...

journal_title：Biochemical and biophysical research communications

authors： Yang J,Wang Y,Sui M,Liu F,Fu Z,Wang QX

更新日期：2015-11-27 00:00:00