A double-blind, parallel-group comparison of flosequinan and enalapril in the treatment of chronic heart failure.

abstract：BACKGROUND:In the acute phase of myocardial infarction (acute MI) marked endothelial damage occurs within the first 24h following thrombolysis with streptokinase. We investigated whether this is associated with a change in levels of vascular endothelial growth factor (VEGF, possibly marking angiogenesis) in the first 2...

journal_title：European heart journal

authors： Chung NA,Lydakis C,Belgore F,Blann AD,Lip GY

更新日期：2002-10-01 00:00:00

abstract：AIMS:The aim of this study is to compare the efficacy of sirolimus-eluting stents (SES) on neointimal growth and vessel remodelling for in-stent restenosis versus de novo coronary artery lesions using serial intravascular ultrasound (IVUS). METHODS AND RESULTS:The study population consisted of 86 patients with in-sten...

journal_title：European heart journal

authors： Degertekin M,Lemos PA,Lee CH,Tanabe K,Sousa JE,Abizaid A,Regar E,Sianos G,van der Giessen WJ,de Feyter PJ,Wuelfert E,Popma JJ,Serruys PW

更新日期：2004-01-01 00:00:00

abstract：AIMS:To investigate the association of estimated total daily sleep duration and daytime nap duration with deaths and major cardiovascular events. METHODS AND RESULTS:We estimated the durations of total daily sleep and daytime naps based on the amount of time in bed and self-reported napping time and examined the assoc...

journal_title：European heart journal

authors： Wang C,Bangdiwala SI,Rangarajan S,Lear SA,AlHabib KF,Mohan V,Teo K,Poirier P,Tse LA,Liu Z,Rosengren A,Kumar R,Lopez-Jaramillo P,Yusoff K,Monsef N,Krishnapillai V,Ismail N,Seron P,Dans AL,Kruger L,Yeates K,Leach

更新日期：2019-05-21 00:00:00

abstract：:To assess if cold-induced vasoconstriction may persist during exercise and contribute to the development of myocardial ischaemia, we studied 11 patients with exertional angina and angiographically proven coronary artery disease, in all cases involving the proximal portion of the left anterior descending artery. Great ...

journal_title：European heart journal

authors： de Servi S,Mussini A,Angoli L,Ferrario M,Bramucci E,Gavazzi A,Ghio S,Ardissino D,Specchia G

更新日期：1985-03-01 00:00:00

abstract：:From a clinicopharmacological standpoint, the urinary excretory potency of diuretics should be assessed comparatively, on the basis of placebo-controlled changes in 24 h natriuresis, following single oral doses administered to healthy adult subjects who are in steady-state habitual external sodium balance. The potency...

journal_title：European heart journal

authors： Reyes AJ

更新日期：1992-12-01 00:00:00

abstract：AIMS:Hitherto, sudden cardiac death in children (SCDc)-defined as sudden cardiac death (SCD) in the 1-18 years old-has been incompletely described in the general population. Knowledge on incidence rates, causes of death and symptoms prior to death is sparse and has been affected by reporting and referral bias. METHODS...

journal_title：European heart journal

authors： Winkel BG,Risgaard B,Sadjadieh G,Bundgaard H,Haunsø S,Tfelt-Hansen J

更新日期：2014-04-01 00:00:00

abstract：Aims:To date, clinical evidence of microvascular dysfunction in patients with heart failure (HF) with preserved ejection fraction (HFpEF) has been limited. We aimed to investigate the prevalence of coronary microvascular dysfunction (CMD) and its association with systemic endothelial dysfunction, HF severity, and myoca...

journal_title：European heart journal

authors： Shah SJ,Lam CSP,Svedlund S,Saraste A,Hage C,Tan RS,Beussink-Nelson L,Ljung Faxén U,Fermer ML,Broberg MA,Gan LM,Lund LH

更新日期：2018-10-01 00:00:00

abstract：:Intracoronary ultrasound was performed at diagnostic coronary angiography and 10 days later in a 45-year-old patient with a 3-day history of acute inferior myocardial infarction. Coronary angiography showed considerable stenosis (80%) in the distal right coronary artery (RCA) (pre the crux) and what appeared to be a d...

journal_title：European heart journal

authors： Ge J,Haude M,Görge G,Liu F,Erbel R

更新日期：1995-08-01 00:00:00

abstract：AIMS:Current data concerning the influence of X-ray contrast media on the incidence of thrombotic complications in interventional cardiology are controversial. The effect of ionic contrast media on acute (< or =72 h) and subacute (< or =30 days) stent thrombosis has not been investigated. METHODS:Three thousand, nine ...

journal_title：European heart journal

authors： Scheller B,Hennen B,Pohl A,Schieffer H,Markwirth T

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:The pathophysiology of myocardial infarction (MI) may differ depending on whether it occurs early or late in life. We tested the hypothesis that risk factor pattern differs according to the age at MI. METHODS:We performed a matched case-control study in the population-based Malmö Preventive Project (n = 33 ...

journal_title：European heart journal

authors： Gränsbo K,Almgren P,Nilsson PM,Hedblad B,Engström G,Melander O

更新日期：2016-07-01 00:00:00

abstract：:The non-invasive quantification of mitral and aortic regurgitation using the left-to-right stroke count ratio (SCR) calculated with gated equilibrium radionuclide ventriculography (RNV), is affected by the overlap of atria and ventricles and the consequent difficult definition of the ventricular regions of interest (R...

journal_title：European heart journal

authors： Sciagrà R,Voth E,Tebbe U,Schicha H,Neuhaus KL

更新日期：1987-10-01 00:00:00

abstract：AIMS:To investigate the efficacy and outcome of emergency percutaneous coronary interventions (PCI) in patients with stent thrombosis. METHODS AND RESULTS:Between 1995 and 2003, 6058 patients underwent bare-metal stent implantation, of which 95 (1.6%) patients suffered from stent thrombosis. The timing of stent thromb...

journal_title：European heart journal

authors： Wenaweser P,Rey C,Eberli FR,Togni M,Tüller D,Locher S,Remondino A,Seiler C,Hess OM,Meier B,Windecker S

更新日期：2005-06-01 00:00:00

abstract：Aim:Hypertrophic cardiomyopathy (HCM) exhibits genetic heterogeneity that is dominated by variation in eight sarcomeric genes. Genetic variation in a large number of non-sarcomeric genes has also been implicated in HCM but not formally assessed. Here we used very large case and control cohorts to determine the extent t...

journal_title：European heart journal

authors： Walsh R,Buchan R,Wilk A,John S,Felkin LE,Thomson KL,Chiaw TH,Loong CCW,Pua CJ,Raphael C,Prasad S,Barton PJ,Funke B,Watkins H,Ware JS,Cook SA

更新日期：2017-12-07 00:00:00

abstract：:The alterations of the beta-adrenoceptor adenylyl cyclase are reviewed. In failing myocardium, the down-regulation of beta 1-adrenoceptors is accompanied by a decrease in steady state mRNA levels, as studied with quantitative polymerase chain reactions in dilated and ischaemic cardiomyopathy. The density of beta 2-adr...

journal_title：European heart journal

authors： Böhm M,Lohse MJ

更新日期：1994-12-01 00:00:00

abstract：:Large-scale trials have demonstrated a consistent mortality reduction from angiotensin converting enzyme (ACE) inhibitor therapy for chronic heart failure. Nonetheless, the pharmacologic and physiologic mechanisms of this favourable affect and the appropriate target population remain controversial. ACE inhibitors exer...

journal_title：European heart journal

authors： Cohn JN

更新日期：1995-12-01 00:00:00

abstract：:Hereditary factors may have a part to play in the development of bicuspid aortic valve. This report concerns a pair of identical twins, probably monozygotic, who required aortic valve replacement as a result of aortic stenosis occurring in bicuspid aortic valves. This supports the contention that there may be a geneti...

journal_title：European heart journal

authors： Godden DJ,Sandhu PS,Kerr F

更新日期：1987-03-01 00:00:00

abstract：:Early treatment with ACE inhibitors of even moderate heart failure is clinically beneficial, even though haemodynamic measurements cannot adequately quantitate such improvement. Neurohumoral assessment is, however, supposed to be more accurate. In 55 patients with moderate heart failure (ejection fraction < or = 35%),...

journal_title：European heart journal

authors： Nussberger J,Fleck E,Bahrmann H,Delius W,Schultheiss HP,Brunner HR

更新日期：1994-12-01 00:00:00

abstract：Aims:Atrial fibrillation (AFib) and atrial flutter (AFlut) are common arrhythmias with increased use of invasive procedures. A steady re-evaluation of relevant safety endpoints is recommended and both quality management and pay-for-performance programs are evolving. Therefore, the aims of this study were (i) to investi...

journal_title：European heart journal

authors： König S,Ueberham L,Schuler E,Wiedemann M,Reithmann C,Seyfarth M,Sause A,Tebbenjohanns J,Schade A,Shin DI,Staudt A,Zacharzowsky U,Andrié R,Wetzel U,Neuser H,Wunderlich C,Kuhlen R,Tijssen JGP,Hindricks G,Bollmann A

更新日期：2018-11-21 00:00:00

abstract：:The clinical expert consensus statement on takotsubo syndrome (TTS) part II focuses on the diagnostic workup, outcome, and management. The recommendations are based on interpretation of the limited clinical trial data currently available and experience of international TTS experts. It summarizes the diagnostic approac...

journal_title：European heart journal

authors： Ghadri JR,Wittstein IS,Prasad A,Sharkey S,Dote K,Akashi YJ,Cammann VL,Crea F,Galiuto L,Desmet W,Yoshida T,Manfredini R,Eitel I,Kosuge M,Nef HM,Deshmukh A,Lerman A,Bossone E,Citro R,Ueyama T,Corrado D,Kurisu S,

更新日期：2018-06-07 00:00:00

abstract：AIMS:The aim of this study was to determine the outcome benefits in those originally assigned atorvastatin in the Anglo-Scandinavian Cardiac Outcomes Trial-8 years after closure of the lipid-lowering arm (LLA) of the trial (ASCOT-LLA) among the U.K. population. METHODS AND RESULTS:ASCOT-LLA was a factorially designed ...

journal_title：European heart journal

authors： Sever PS,Chang CL,Gupta AK,Whitehouse A,Poulter NR,ASCOT Investigators.

更新日期：2011-10-01 00:00:00

abstract：:We studied the effects of angiotensin (Ang) I and II in a variety of isolated human cardiac tissues contracting under physiological conditions (37 degrees C, 60 beats.min-1). Ang I and II consistently increased the peak developed force of human atrial muscles by 30-40%, an effect that was completely blocked by 10(-6) ...

journal_title：European heart journal

authors： Holubarsch C,Schmidt-Schweda S,Knorr A,Duis J,Pieske B,Ruf T,Fasol R,Hasenfuss G,Just H

更新日期：1994-12-01 00:00:00

abstract：AIMS:Atrial fibrillation (AF) is associated with abnormal sarcoplasmic reticulum (SR) calcium release, which is promoted by adenosine A(2A) receptor (A(2A)R) activation. Here, we tested the hypothesis that abnormal calcium release in AF is linked to A(2A)R remodelling. METHODS AND RESULTS:Western blotting and quantita...

journal_title：European heart journal

authors： Llach A,Molina CE,Prat-Vidal C,Fernandes J,Casadó V,Ciruela F,Lluís C,Franco R,Cinca J,Hove-Madsen L

更新日期：2011-03-01 00:00:00

abstract：AIM:Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) has been suggested as an independent predictor of cardiovascular events in epidemiological studies. We sought to evaluate Lp-PLA(2) as a risk factor for future cardiovascular events in patients with acute coronary syndromes (ACS) and to elucidate the relationshi...

journal_title：European heart journal

authors： Oldgren J,James SK,Siegbahn A,Wallentin L

更新日期：2007-03-01 00:00:00

abstract：AIMS:Women, particularly younger women, hospitalized with acute myocardial infarction have been found to have poorer prognosis than men. A large proportion of deaths due to myocardial infarction, however, occur in the pre-hospital phase. We set out to analyse age-specific sex differences in survival after myocardial in...

journal_title：European heart journal

authors： Rosengren A,Spetz CL,Köster M,Hammar N,Alfredsson L,Rosén M

更新日期：2001-02-01 00:00:00

abstract：:In a prospective trial in 124 patients with acute myocardial infarction, Holter and surface ECG recordings were obtained simultaneously and compared for their ability to assess thrombolysis-induced ST segment changes. Accuracy in predicting patency of the infarct-related artery was evaluated in both methods. Success o...

journal_title：European heart journal

authors： Zabel M,Hohnloser SH,Parussel A,Just H

更新日期：1992-12-01 00:00:00

abstract：:This report concerns a patient with cardiac manifestation of Whipple's disease. For the first time, the gene that encodes the 16s rRNA of Tropheryma whippelii was identified in a native aortic valve by means of a polymerase chain reaction technique. DNA amplification gives evidence of Tropheryma whippelii as a causati...

journal_title：European heart journal

authors： Wendler D,Mendoza E,Schleiffer T,Zander M,Maier M

更新日期：1995-03-01 00:00:00

abstract：AIMS:Major guidelines recommend lowering systolic blood pressure (SBP) to <140 mmHg in all hypertensives, but evidence is missing whether this is beneficial in (i) uncomplicated hypertensives, (ii) grade 1 hypertensives, and (iii) elderly hypertensives. Providing this missing evidence is important to justify efforts an...

journal_title：European heart journal

authors： Zhang Y,Zhang X,Liu L,Zanchetti A,FEVER Study Group.

更新日期：2011-06-01 00:00:00

abstract：AIMS:Urinary albumin excretion increases during acute myocardial infarction but little is known on the prognostic significance and the pathophysiological mechanisms of microalbuminuria in this clinical setting. The primary aim of the study was to examine whether urinary albumin excretion has predictive power for 1-year...

journal_title：European heart journal

authors： Berton G,Cordiano R,Palmieri R,Cucchini F,De Toni R,Palatini P

更新日期：2001-08-01 00:00:00

abstract：:Haemodynamic effects of pharmacological doses of insulin during acute ischaemic heart failure were studied in 8 dogs. Severe depression of left ventricular function was induced by the injection of 50 micron plastic microspheres into the left main coronary artery. This was demonstrated by a significant increase in left...

journal_title：European heart journal

authors： Reikerås O,Gunnes P,Sørlie D,Ekroth R,Jorde R,Mjøs OD

更新日期：1985-05-01 00:00:00

abstract：AIMS:To investigate whether the benefit of thrombolytic therapy was sustained beyond the first decade. We report the 10-14 year outcome of 533 patients who were randomized to treatment with intracoronary streptokinase or to conventional therapy during the years 1980-1985. METHODS AND RESULTS:Details of survival and ca...

journal_title：European heart journal

authors： Maas AC,van Domburg RT,Deckers JW,Vermeer F,Remme WJ,Kamp O,Manger Cats V,Simoons ML

更新日期：1999-06-01 00:00:00