Abstract:
:In a prospective trial in 124 patients with acute myocardial infarction, Holter and surface ECG recordings were obtained simultaneously and compared for their ability to assess thrombolysis-induced ST segment changes. Accuracy in predicting patency of the infarct-related artery was evaluated in both methods. Success or failure of thrombolysis was determined angiographically 90 min after the start of therapy. For both methods, sensitivity, specificity, and positive predictive value for correct prediction of the perfusion status ranged between 64% and 92%. However, the negative predictive value was considerably lower (40-53%). There were no significant differences in any parameter evaluated for either method. Thus, two surface ECG recordings before and 2 h after the start of therapy yield the same predictive value as continuous Holter monitoring with respect to thrombolysis-induced coronary artery reperfusion. However, for triage of patients to early coronary interventions, more sophisticated methods are needed for non-invasive prediction of coronary artery patency due to the low negative predictive value of ST segment analysis.
journal_name
Eur Heart Jjournal_title
European heart journalauthors
Zabel M,Hohnloser SH,Parussel A,Just Hdoi
10.1093/oxfordjournals.eurheartj.a060114subject
Has Abstractpub_date
1992-12-01 00:00:00pages
1619-25issue
12eissn
0195-668Xissn
1522-9645journal_volume
13pub_type
杂志文章abstract:AIMS:Trans-fatty acids (TFAs) are generated by the food industry and also occur naturally in trace amounts in dairy products. For the latter, beneficial health effects have been claimed, while there are numerous reports about TFA of industrial origin being hazardous to human health. Therefore, we aimed to investigate t...
journal_title:European heart journal
pub_type: 杂志文章
doi:10.1093/eurheartj/ehv446
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更新日期:1989-08-01 00:00:00
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journal_title:European heart journal
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更新日期:2012-07-01 00:00:00
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pub_type: 共识发展会议,杂志文章
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更新日期:1996-12-01 00:00:00
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journal_title:European heart journal
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1992-08-01 00:00:00
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更新日期:1994-09-01 00:00:00
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