Sudden cardiac death. How to reduce the number of victims?

abstract：:The efficacy of nifedipine and prazosin in the treatment of Raynaud's phenomenon was assessed in a prospective double-blind randomized cross-over trial in 15 patients. Each patient received one week of nifedipine 20 mg TID, one week of prazosin 1 mg TID, and 2 weeks of placebo. Nifedipine was shown to be effective in ...

journal_title：European heart journal

authors： Kahan A,Foult JM,Weber S,Amor B,Menkes CJ,Degeorges M

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:There is much interest in reported associations between serum C-reactive protein and incident ischaemic heart disease. It is uncertain what this association represents. We aimed to assess the effect of confounding from a number of different sources in the Caerphilly Prospective Heart Disease Study and in par...

journal_title：European heart journal

authors： Mendall MA,Strachan DP,Butland BK,Ballam L,Morris J,Sweetnam PM,Elwood PC

更新日期：2000-10-01 00:00:00

abstract：AIMS:Our aims were to evaluate the distribution of troponin I concentrations in population cohorts across Europe, to characterize the association with cardiovascular outcomes, to determine the predictive value beyond the variables used in the ESC SCORE, to test a potentially clinically relevant cut-off value, and to ev...

journal_title：European heart journal

authors： Blankenberg S,Salomaa V,Makarova N,Ojeda F,Wild P,Lackner KJ,Jørgensen T,Thorand B,Peters A,Nauck M,Petersmann A,Vartiainen E,Veronesi G,Brambilla P,Costanzo S,Iacoviello L,Linden G,Yarnell J,Patterson CC,Everett BM

更新日期：2016-08-07 00:00:00

abstract：:This overview provides a Europe-wide update on the current burden of cardiovascular disease, and specifically of coronary heart disease and stroke. Cardiovascular disease continues to cause a large proportion of deaths and disability in Europe, and places a substantial burden on the health care systems and economies o...

journal_title：European heart journal

authors： Nichols M,Townsend N,Scarborough P,Rayner M

更新日期：2013-10-01 00:00:00

abstract：AIMS:Genome-wide association studies have previously identified INSIG2 as a candidate gene for plasma low-density lipoprotein cholesterol (LDL-c). However, we suspect a role for CCDC93 in the same locus because of its involvement in the recycling of the LDL-receptor (LDLR). METHODS AND RESULTS:Characterization of the ...

journal_title：European heart journal

authors： Rimbert A,Dalila N,Wolters JC,Huijkman N,Smit M,Kloosterhuis N,Riemsma M,van der Veen Y,Singla A,van Dijk F,Biobank-Based Integrative Omics Studies Consortium.,Frikke-Schmidt R,Burstein E,Tybjærg-Hansen A,van de Sluis B,Kui

更新日期：2020-03-01 00:00:00

abstract：AIMS:Carotid-femoral pulse wave velocity (PWV), a direct measure of aortic stiffness, has become increasingly important for total cardiovascular (CV) risk estimation. Its application as a routine tool for clinical patient evaluation has been hampered by the absence of reference values. The aim of the present study is t...

journal_title：European heart journal

authors： Reference Values for Arterial Stiffness' Collaboration.

更新日期：2010-10-01 00:00:00

abstract：:Thrombolytic therapy is a practical, effective approach to the management of acute myocardial infarction that is widely used in Europe today. Early European trials demonstrated a clear reduction in mortality in patients who received thrombolytic therapy compared with those given conventional treatment. The findings of...

journal_title：European heart journal

authors： Vahanian A

更新日期：1996-09-01 00:00:00

abstract：:AIMS Pre-treatment with clopidogrel results in a reduction of ischaemic events in non-ST-elevation acute coronary syndromes. Data on upstream clopidogrel in the setting of primary percutaneous coronary intervention (PCI) are limited. The aim of this study was to investigate whether clopidogrel loading before arrival a...

journal_title：European heart journal

authors： Dörler J,Edlinger M,Alber HF,Altenberger J,Benzer W,Grimm G,Huber K,Pachinger O,Schuchlenz H,Siostrzonek P,Zenker G,Weidinger F,Austrian Acute PCI Investigators.

更新日期：2011-12-01 00:00:00

abstract：AIMS:To evaluate clinical disease expression, non-invasive diagnosis, and prognosis in families with dominant vs. recessive arrhythmogenic right ventricular cardiomyopathy (ARVC) due to mutations in related desmosomal proteins plakophilin-2 (PKP2) and plakoglobin (JUP), respectively. METHODS AND RESULTS:One hundred an...

journal_title：European heart journal

authors： Antoniades L,Tsatsopoulou A,Anastasakis A,Syrris P,Asimaki A,Panagiotakos D,Zambartas C,Stefanadis C,McKenna WJ,Protonotarios N

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Recently, a new exercise test criterion diagnosing coronary artery disease was proposed, based on a composite of changes in Q-, R- and S-waves: the QRS score. We compared this new criterion with conventional ST-segment depression and other compositions of Q-, R- and S-wave changes in patients and normals and...

journal_title：European heart journal

authors： van Campen CM,Visser FC,Visser CA

更新日期：1996-05-01 00:00:00

abstract：:Promising approaches towards new therapeutic strategies in coronary heart disease might emerge from an improved pathophysiological understanding of the role of certain peptides, which require a localizing event for their accumulation or expression in the coronary vasculature. Temporal myocardial ischaemia or hypoperfu...

journal_title：European heart journal

authors： Holtz J,Goetz RM

更新日期：1991-12-01 00:00:00

abstract：:This report describes a patient with left atrial ball thrombus which was detected during echocardiographic evaluation of combined mitral-aortic valve disease. Surgical correction was performed entirely on the basis of the echocardiographic diagnosis. ...

journal_title：European heart journal

authors： Schäfer RO,Evers G,Morgan P,Thiel H

更新日期：1992-02-01 00:00:00

abstract：:Food constituents can either promote cardiovascular health or serve in its demise. In view of the lack of more effective pharmacological interventions in cardiovascular disease (CVDs), attention has focused on the potential protective effects of diet. Food components and their metabolites are emerging as major regulat...

journal_title：European heart journal

authors： Lionetti V,Tuana BS,Casieri V,Parikh M,Pierce GN

更新日期：2019-02-14 00:00:00

abstract：:Thrombolytic treatment efficacy is greater when the delay between onset of pain and treatment is short. One way to shorten this delay is to give treatment at home, but one cannot recommend this technique if it has not been demonstrated first, that pre-hospital thrombolysis is feasible and safe, and second, that it is ...

journal_title：European heart journal

authors： Castaigne AD,Hervé C,Duval-Moulin AM,Gaillard M,Dubois-Randé JL,Lellouche D

更新日期：1990-08-01 00:00:00

abstract：AIMS:Whether the association between fibrinogen and cardiovascular events reflects an association with advanced atherosclerosis in general, or rupture-prone plaques in particular, is unclear. We examined whether fibrinogen predicts incidence of ischaemic stroke, advanced atherosclerosis (measured as carotid artery sten...

journal_title：European heart journal

authors： Kofoed SC,Wittrup HH,Sillesen H,Nordestgaard BG

更新日期：2003-03-01 00:00:00

abstract：AIMS:This study was designed to characterise both the systolic and diastolic mechanical properties of regions with different degrees of myocardial ischaemic injury after reperfused acute myocardial infarction (AMI). METHODS AND RESULTS:Fourteen dogs underwent 90-min coronary artery occlusion followed by reperfusion. I...

journal_title：European heart journal

authors： Azevedo CF,Amado LC,Kraitchman DL,Gerber BL,Osman NF,Rochitte CE,Edvardsen T,Lima JA

更新日期：2004-08-01 00:00:00

abstract：AIMS:Hypertrophic cardiomyopathy (HCM) is a disease with marked regional differences in wall thickness. However, the relation between myocardial function and wall thickness has not been well studied. Ultrasonic strain rate (SR) imaging makes it possible to study the regional myocardial deformation. We investigated whet...

journal_title：European heart journal

authors： Ganame J,Mertens L,Eidem BW,Claus P,D'hooge J,Havemann LM,McMahon CJ,Elayda MA,Vaughn WK,Towbin JA,Ayres NA,Pignatelli RH

更新日期：2007-12-01 00:00:00

abstract：:The natriuretic peptides (NPs) family, including atrial, B-type, and C-type NPs, is a group of hormones possessing relevant haemodynamic and anti-remodelling actions in the cardiovascular (CV) system. Due to their diuretic, natriuretic, vasorelaxant, anti-proliferative, and anti-hypertrophic effects, they are involved...

journal_title：European heart journal

authors： Volpe M,Rubattu S,Burnett J Jr

更新日期：2014-02-01 00:00:00

abstract：:Advances in molecular genetics present new opportunities and challenges for cardiologists who manage patients and families with cardiomyopathies. The aims of this position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases are to review the general issues related to ge...

journal_title：European heart journal

authors： Charron P,Arad M,Arbustini E,Basso C,Bilinska Z,Elliott P,Helio T,Keren A,McKenna WJ,Monserrat L,Pankuweit S,Perrot A,Rapezzi C,Ristic A,Seggewiss H,van Langen I,Tavazzi L,European Society of Cardiology Working Group on

更新日期：2010-11-01 00:00:00

abstract：:Falipamil hydrochloride (AQA 39) is a new antiarrhythmic agent structurally related to verapamil. We evaluated the electrophysiologic properties of intravenous falipamil (1.5 mg kg-1 within 20 minutes) in 12 patients. The spontaneous cycle length was significantly (P less than 0.001) prolonged (+79 +/- 59 ms). Atriove...

journal_title：European heart journal

authors： Lévy S,Mètge M,Hilaire J,Cointe R,Bru P,Eychenne JL,Gérard R

更新日期：1987-11-01 00:00:00

abstract：:Haemodynamic effects of pharmacological doses of insulin during acute ischaemic heart failure were studied in 8 dogs. Severe depression of left ventricular function was induced by the injection of 50 micron plastic microspheres into the left main coronary artery. This was demonstrated by a significant increase in left...

journal_title：European heart journal

authors： Reikerås O,Gunnes P,Sørlie D,Ekroth R,Jorde R,Mjøs OD

更新日期：1985-05-01 00:00:00

abstract：Aims:The ESC-EHRA Atrial Fibrillation Ablation Long-Term registry is a prospective, multinational study that aims at providing an accurate picture of contemporary real-world ablation for atrial fibrillation (AFib) and its outcome. Methods and results:A total of 104 centres in 27 European countries participated and wer...

journal_title：European heart journal

authors： Arbelo E,Brugada J,Blomström-Lundqvist C,Laroche C,Kautzner J,Pokushalov E,Raatikainen P,Efremidis M,Hindricks G,Barrera A,Maggioni A,Tavazzi L,Dagres N,on the behalf of the ESC-EHRA Atrial Fibrillation Ablation Long-term Regis

更新日期：2017-05-01 00:00:00

abstract：:The present review summarizes the available information on the effects of the three major classes of antianginal agents (nitrates, calcium and beta-blockers) on myocardial energy metabolism. It also discusses the role of some new molecules (L-carnitine, trimetazidine and ranolazine) that have been proposed as an alter...

journal_title：European heart journal

authors： Chierchia SL,Fragasso G

更新日期：1993-11-01 00:00:00

abstract：:To analyse quantitatively a coronary arterial segment from a cineangiogram, an end-diastolic or neighbouring frame is usually selected. However, different cardiologists may select other (although usually neighbouring) frames, even when the same selection criteria are followed. It is also possible that the frames are s...

journal_title：European heart journal

authors： Reiber JH,van Eldik-Helleman P,Kooijman CJ,Tijssen JG,Serruys PW

更新日期：1989-11-01 00:00:00

abstract：AIMS:Despite advances in the treatment of acute coronary syndromes based on randomized trial data and published guidelines, the extent to which such treatments are applied in practice remains uncertain. Data from clinical trials derive from selected geographical areas and in highly selected populations of patients, and...

journal_title：European heart journal

authors： Fox KA,Goodman SG,Klein W,Brieger D,Steg PG,Dabbous O,Avezum A

更新日期：2002-08-01 00:00:00

abstract：AIMS:There have been substantial declines in cerebrovascular disease mortality across much of Europe, mirroring trends in deaths from cardiovascular disease as a whole. No study has investigated trends in cerebrovascular disease, and its subtypes within all European countries. This study aimed to examine sex-specific t...

journal_title：European heart journal

authors： Shah R,Wilkins E,Nichols M,Kelly P,El-Sadi F,Wright FL,Townsend N

更新日期：2019-03-01 00:00:00

abstract：AIMS:In the dual antiplatelet therapy (DAPT) study, continued thienopyridine beyond 12 months after drug-eluting stent placement was associated with increased mortality compared with placebo. We sought to evaluate factors related to mortality in randomized patients receiving either drug-eluting or bare metal stents in ...

journal_title：European heart journal

authors： Mauri L,Elmariah S,Yeh RW,Cutlip DE,Steg PG,Windecker S,Wiviott SD,Cohen DJ,Massaro JM,D'Agostino RB Sr,Braunwald E,Kereiakes DJ,DAPT Study Investigators.

更新日期：2016-01-21 00:00:00

abstract：:Increased QT dispersion, which has been proposed as a marker of ventricular repolarization inhomogeneity, may predispose to ventricular arrhythmias. Data on QT dispersion in patients with congestive heart failure are scarce. In this study, conventional 12-lead ECGs were recorded in 135 consecutive patients with conges...

journal_title：European heart journal

authors： Fei L,Goldman JH,Prasad K,Keeling PJ,Reardon K,Camm AJ,McKenna WJ

更新日期：1996-02-01 00:00:00

abstract：:A group of investigators met for two days in Santorini, Greece, to discuss progress in the field of identification and treatment of high risk/vulnerable atherosclerotic plaques and patients. Many differences in the manner in which terms are being utilized were noted. It was recognized that increased understanding of t...

journal_title：European heart journal

authors： Schaar JA,Muller JE,Falk E,Virmani R,Fuster V,Serruys PW,Colombo A,Stefanadis C,Ward Casscells S,Moreno PR,Maseri A,van der Steen AF

更新日期：2004-06-01 00:00:00

abstract：AIMS:Prophylactic administration of N-acetylcysteine (NAC) (600mg orally twice daily), along with hydration, prevents contrast agent-associated nephrotoxicity (CAN) induced by a low dose of non-ionic, low-osmolality contrast dye. We tested whether a double dose of NAC is more effective to prevent CAN. METHODS AND RESU...

journal_title：European heart journal

authors： Briguori C,Colombo A,Violante A,Balestrieri P,Manganelli F,Paolo Elia P,Golia B,Lepore S,Riviezzo G,Scarpato P,Focaccio A,Librera M,Bonizzoni E,Ricciardelli B

更新日期：2004-02-01 00:00:00